JP2009526794A5 - - Google Patents
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- Publication number
- JP2009526794A5 JP2009526794A5 JP2008554654A JP2008554654A JP2009526794A5 JP 2009526794 A5 JP2009526794 A5 JP 2009526794A5 JP 2008554654 A JP2008554654 A JP 2008554654A JP 2008554654 A JP2008554654 A JP 2008554654A JP 2009526794 A5 JP2009526794 A5 JP 2009526794A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkoxy
- independently
- group
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC(C1)CN2C1CC(CC(CC1)C3C1CN(*)C3)C2 Chemical compound CC(C1)CN2C1CC(CC(CC1)C3C1CN(*)C3)C2 0.000 description 16
- MUGSKSNNEORSJG-UHFFFAOYSA-N C1C=CCOC1 Chemical compound C1C=CCOC1 MUGSKSNNEORSJG-UHFFFAOYSA-N 0.000 description 2
- NDJHJSODIHFOMT-UHFFFAOYSA-N C1NC(C2CCNCC2)NC1 Chemical compound C1NC(C2CCNCC2)NC1 NDJHJSODIHFOMT-UHFFFAOYSA-N 0.000 description 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N C1NCCOC1 Chemical compound C1NCCOC1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 description 2
- VBOVKNXVKDRXIB-UHFFFAOYSA-N C1OCC([O]2CCCCC2)=C1 Chemical compound C1OCC([O]2CCCCC2)=C1 VBOVKNXVKDRXIB-UHFFFAOYSA-N 0.000 description 2
- CRCRUNUNNSAEEN-UHFFFAOYSA-N COCC1C(CCCC2)N2CCC1 Chemical compound COCC1C(CCCC2)N2CCC1 CRCRUNUNNSAEEN-UHFFFAOYSA-N 0.000 description 2
- MBFDHESEJDXGPW-UHFFFAOYSA-N CN(C(CC1)C2)C1CC2OC Chemical compound CN(C(CC1)C2)C1CC2OC MBFDHESEJDXGPW-UHFFFAOYSA-N 0.000 description 1
- ZSXGLVDWWRXATF-UHFFFAOYSA-N CN(C)C(OC)OC Chemical compound CN(C)C(OC)OC ZSXGLVDWWRXATF-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006007049 | 2006-02-15 | ||
| PCT/EP2007/001213 WO2007093365A2 (en) | 2006-02-15 | 2007-02-13 | Novel amino alcohol-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009526794A JP2009526794A (ja) | 2009-07-23 |
| JP2009526794A5 true JP2009526794A5 (https=) | 2010-04-02 |
Family
ID=38069213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008554654A Pending JP2009526794A (ja) | 2006-02-15 | 2007-02-13 | 新規なアミノアルコール置換アリールチエノピリミジノン、それらの製造方法及び薬剤としてそれらの使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8853208B2 (https=) |
| EP (1) | EP1987042B1 (https=) |
| JP (1) | JP2009526794A (https=) |
| KR (1) | KR20080096670A (https=) |
| CN (1) | CN101384605A (https=) |
| AR (1) | AR059520A1 (https=) |
| AU (1) | AU2007214710A1 (https=) |
| BR (1) | BRPI0707870A2 (https=) |
| CA (1) | CA2636879A1 (https=) |
| IL (1) | IL193342A0 (https=) |
| TW (1) | TW200801022A (https=) |
| UY (1) | UY30164A1 (https=) |
| WO (1) | WO2007093365A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2018380T3 (pl) * | 2006-05-19 | 2012-05-31 | Abbvie Bahamas Ltd | Skondensowane azabicykliczne pochodne alkanowe podstawione bicykloheterocyklem o aktywności wobec OUN |
| UY31968A (es) | 2008-07-09 | 2010-01-29 | Sanofi Aventis | Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos |
| AU2010276441B2 (en) * | 2009-07-21 | 2015-07-02 | Gilead Sciences, Inc. | Inhibitors of Flaviviridae viruses |
| WO2011031669A1 (en) | 2009-09-09 | 2011-03-17 | Gilead Sciences, Inc. | Inhibitors of flaviviridae viruses |
| US8524764B2 (en) | 2010-01-15 | 2013-09-03 | Gilead Sciences, Inc. | Inhibitors of Flaviviridae viruses |
| MX2012008211A (es) | 2010-01-15 | 2012-08-08 | Gilead Sciences Inc | Inhibidores de virus flaviviridae. |
| HUP1100241A3 (en) | 2011-05-06 | 2013-12-30 | Richter Gedeon Nyrt | Oxetane substituted pyrimidones |
| PT2734515E (pt) | 2011-07-13 | 2016-03-11 | Gilead Sciences Inc | Derivados de ácido tiofen-2-carboxílico úteis como inibidores de vírus flaviviridae |
| US8759544B2 (en) | 2012-08-17 | 2014-06-24 | Gilead Sciences, Inc. | Synthesis of an antiviral compound |
| US8927741B2 (en) | 2012-08-17 | 2015-01-06 | Gilead Sciences, Inc. | Synthesis of an antiviral compound |
| US8841340B2 (en) | 2012-08-17 | 2014-09-23 | Gilead Sciences, Inc. | Solid forms of an antiviral compound |
| SG11201804901WA (en) | 2015-12-22 | 2018-07-30 | SHY Therapeutics LLC | Compounds for the treatment of cancer and inflammatory disease |
| EA201992780A1 (ru) | 2017-06-21 | 2020-06-02 | ШАЙ ТЕРАПЬЮТИКС ЭлЭлСи | Соединения, которые взаимодействуют с суперсемейством ras, для лечения рака, воспалительных заболеваний, ras-опатий и фиброзного заболевания |
| US12391705B2 (en) | 2018-12-19 | 2025-08-19 | Shy Therapeutics, Llc | Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0124627D0 (en) * | 2001-10-15 | 2001-12-05 | Smithkline Beecham Plc | Novel compounds |
| AU2002360387B2 (en) * | 2001-11-13 | 2008-08-07 | Emisphere Technologies, Inc. | Phenoxy amine compounds and compositions for delivering active agents |
| DE10233817A1 (de) * | 2002-07-25 | 2004-02-12 | Aventis Pharma Deutschland Gmbh | Substituierte Diarylheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| DE10238865A1 (de) * | 2002-08-24 | 2004-03-11 | Boehringer Ingelheim International Gmbh | Neue Carbonsäureamid-Verbindungen mit MCH-antagonistischer Wirkung, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| AU2003287880A1 (en) * | 2002-12-11 | 2004-06-30 | 7Tm Pharma A/S | Cyclic quinoline compounds for use in mch receptor related disorders |
| DE10306250A1 (de) * | 2003-02-14 | 2004-09-09 | Aventis Pharma Deutschland Gmbh | Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| JP2007509158A (ja) * | 2003-10-23 | 2007-04-12 | グラクソ グループ リミテッド | 肥満、糖尿病、うつ病及び不安を治療するためのｍｃｈｒ１アンタゴニストとしての３−（４−アミノフェニル）チエノピリミド−４−オン誘導体 |
| CN1930126A (zh) * | 2004-03-05 | 2007-03-14 | 万有制药株式会社 | 吡啶酮衍生物 |
| WO2005103039A1 (en) * | 2004-04-15 | 2005-11-03 | Neurocrine Biosciences, Inc. | 2- (3-aminopyrrolidin-1-yl) pyridines as melanin-concentrating hormone receptor an tagonists |
-
2007
- 2007-02-13 WO PCT/EP2007/001213 patent/WO2007093365A2/en not_active Ceased
- 2007-02-13 EP EP07711519.4A patent/EP1987042B1/en not_active Not-in-force
- 2007-02-13 KR KR1020087020095A patent/KR20080096670A/ko not_active Withdrawn
- 2007-02-13 TW TW096105357A patent/TW200801022A/zh unknown
- 2007-02-13 CN CNA2007800056310A patent/CN101384605A/zh active Pending
- 2007-02-13 CA CA002636879A patent/CA2636879A1/en not_active Abandoned
- 2007-02-13 JP JP2008554654A patent/JP2009526794A/ja active Pending
- 2007-02-13 AU AU2007214710A patent/AU2007214710A1/en not_active Abandoned
- 2007-02-13 BR BRPI0707870-6A patent/BRPI0707870A2/pt not_active IP Right Cessation
- 2007-02-15 AR ARP070100659A patent/AR059520A1/es not_active Application Discontinuation
- 2007-02-15 UY UY30164A patent/UY30164A1/es unknown
-
2008
- 2008-08-10 IL IL193342A patent/IL193342A0/en unknown
- 2008-08-14 US US12/191,678 patent/US8853208B2/en not_active Expired - Fee Related
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