BRPI0707870A2 - ariltienopirimidinonas substituÍdas com amino Álcool, processo para sua preparaÇço e seu uso como medicamentos - Google Patents

Info

Publication number

BRPI0707870A2

BRPI0707870A2 BRPI0707870-6A BRPI0707870A BRPI0707870A2 BR PI0707870 A2 BRPI0707870 A2 BR PI0707870A2 BR PI0707870 A BRPI0707870 A BR PI0707870A BR PI0707870 A2 BRPI0707870 A2 BR PI0707870A2

Authority

BR

Brazil

Prior art keywords

alkyl

formula

alkoxy

independently

hydroxy

Prior art date

2006-02-15

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• 238000000034 method Methods 0.000 title claims abstract description 172
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• 229940079593 drug Drugs 0.000 title claims abstract description 17
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• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 title 1
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• 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 252
• 150000001875 compounds Chemical class 0.000 claims description 251
• -1 (C 1 -C 6 alkyl Chemical group 0.000 claims description 223
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• 229910052760 oxygen Inorganic materials 0.000 claims description 100
• 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims description 91
• 125000005842 heteroatom Chemical group 0.000 claims description 90
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• 125000004433 nitrogen atom Chemical group N* 0.000 claims description 72
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• IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 60
• QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 54
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• 125000004122 cyclic group Chemical group 0.000 claims description 51
• 239000004480 active ingredient Substances 0.000 claims description 43
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 40
• 125000001424 substituent group Chemical group 0.000 claims description 40
• NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 29
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• 125000000217 alkyl group Chemical group 0.000 claims description 28
• 238000011282 treatment Methods 0.000 claims description 28
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• 238000006243 chemical reaction Methods 0.000 claims description 23
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• 125000003118 aryl group Chemical group 0.000 claims description 22
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• 125000000623 heterocyclic group Chemical group 0.000 claims description 11
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