JP2009526010A5 - - Google Patents

Download PDF

Info

Publication number
JP2009526010A5
JP2009526010A5 JP2008553739A JP2008553739A JP2009526010A5 JP 2009526010 A5 JP2009526010 A5 JP 2009526010A5 JP 2008553739 A JP2008553739 A JP 2008553739A JP 2008553739 A JP2008553739 A JP 2008553739A JP 2009526010 A5 JP2009526010 A5 JP 2009526010A5
Authority
JP
Japan
Prior art keywords
seq
monoclonal antibody
antibody
hgfr
cdr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008553739A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009526010A (ja
JP5306828B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2007/051066 external-priority patent/WO2007090807A1/en
Publication of JP2009526010A publication Critical patent/JP2009526010A/ja
Publication of JP2009526010A5 publication Critical patent/JP2009526010A5/ja
Application granted granted Critical
Publication of JP5306828B2 publication Critical patent/JP5306828B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2008553739A 2006-02-06 2007-02-05 腫瘍の治療のための、抗metモノクローナル抗体、フラグメント及びそのベクター、並びに対応する製品 Active JP5306828B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06101345.4 2006-02-06
EP06101345 2006-02-06
PCT/EP2007/051066 WO2007090807A1 (en) 2006-02-06 2007-02-05 Anti-met monoclonal antibody, fragments and vectors thereof, for the treatment of tumors and corresponding products

Publications (3)

Publication Number Publication Date
JP2009526010A JP2009526010A (ja) 2009-07-16
JP2009526010A5 true JP2009526010A5 (enExample) 2010-02-25
JP5306828B2 JP5306828B2 (ja) 2013-10-02

Family

ID=36616994

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008553739A Active JP5306828B2 (ja) 2006-02-06 2007-02-05 腫瘍の治療のための、抗metモノクローナル抗体、フラグメント及びそのベクター、並びに対応する製品

Country Status (21)

Country Link
US (2) US8388958B2 (enExample)
EP (2) EP2192188A1 (enExample)
JP (1) JP5306828B2 (enExample)
KR (1) KR101429297B1 (enExample)
CN (1) CN101379192B (enExample)
AT (1) ATE514715T1 (enExample)
AU (1) AU2007213804B2 (enExample)
BR (1) BRPI0707480A8 (enExample)
CA (1) CA2638889C (enExample)
CY (1) CY1111884T1 (enExample)
DK (1) DK1981981T3 (enExample)
EA (1) EA015580B1 (enExample)
ES (1) ES2368864T3 (enExample)
IL (1) IL192879A (enExample)
MX (1) MX2008009833A (enExample)
PL (1) PL1981981T3 (enExample)
PT (1) PT1981981E (enExample)
SG (2) SG169383A1 (enExample)
SI (1) SI1981981T1 (enExample)
WO (1) WO2007090807A1 (enExample)
ZA (1) ZA200806559B (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2014681A1 (en) 2007-07-12 2009-01-14 Pierre Fabre Medicament Novel antibodies inhibiting c-met dimerization, and uses thereof
IL198545A0 (en) 2008-05-14 2011-07-31 Metheresis Translational Res Sa High affinity binding site of hgfr and methods for identification of antagonists thereof
EP2127683A1 (en) * 2008-05-29 2009-12-02 Metheresis Translational Research SA Anti-Met monoclonal antibody, fragments and derivatives thereof for use in tumor imaging, corresponding compositions and kits
PA8849001A1 (es) 2008-11-21 2010-06-28 Lilly Co Eli Anticuerpos de c-met
EP2287197A1 (en) * 2009-08-21 2011-02-23 Pierre Fabre Medicament Anti-cMET antibody and its use for the detection and the diagnosis of cancer
KR101671378B1 (ko) * 2009-10-30 2016-11-01 삼성전자 주식회사 c-Met에 특이적으로 결합하는 항체 및 그의 용도
KR101748707B1 (ko) 2009-11-27 2017-06-20 삼성전자주식회사 c-Met에 특이적으로 결합하는 항체 및 그를 이용한 암 진단용 키트
KR101814571B1 (ko) 2010-03-10 2018-01-04 젠맵 에이/에스 C―met에 대한 모노클로날 항체
WO2011125458A1 (ja) 2010-04-02 2011-10-13 富士レビオ株式会社 抗癌剤の効果の診断用マーカー
US9169329B2 (en) * 2010-06-01 2015-10-27 Ludwig Institute For Cancer Research Antibodies directed to the receptor tyrosine kinase c-Met
CA2809677A1 (en) * 2010-09-03 2012-03-08 Academia Sinica Anti-c-met antibody and methods of use thereof
WO2012059561A1 (en) 2010-11-03 2012-05-10 Argen-X-Bv Anti c-met antibodies
PL2500036T3 (pl) * 2011-03-18 2014-10-31 Metheresis Translational Res Sa Inhibitory met do zwiększania skuteczności radioterapii
EP2758430A4 (en) 2011-09-20 2015-06-03 Lilly Co Eli ANTI-C-MET ANTIBODY
WO2013064700A2 (en) 2011-11-03 2013-05-10 Argen-X B.V. Chimeric polypeptides and methods of use
CN104066748A (zh) 2011-11-21 2014-09-24 霍夫曼-拉罗奇有限公司 抗c-met抗体的纯化
EP2785741A1 (en) 2011-12-02 2014-10-08 Cancer Research Technology Limited Antibodies against hgf - receptor and uses
US8900582B2 (en) 2011-12-22 2014-12-02 Samsung Electronics Co., Ltd. Deimmunized anti c-Met humanized antibodies and uses thereof
CN103382223B (zh) * 2012-04-01 2015-06-10 上海益杰生物技术有限公司 针对表皮生长因子受体隐蔽表位和t细胞抗原的多功能抗体多肽
CA2877573A1 (en) * 2012-06-21 2013-12-27 Sorrento Therapeutics, Inc. Antigen binding proteins that bind c-met
ITTO20130012A1 (it) 2013-01-09 2014-07-10 Metheresis Translational Res S A Nuovi frammenti anticorpali, relative composizioni ed usi
CN107001471B (zh) 2014-09-16 2022-01-18 西福根有限公司 抗met抗体和组合物
WO2016149116A1 (en) * 2015-03-13 2016-09-22 University Of Maryland, Baltimore Antibodies targeting s100b and methods of use
KR20170136536A (ko) 2015-03-16 2017-12-11 셀덱스 쎄라퓨틱스, 인크. 항-met 항체 및 그 사용 방법
GB201611123D0 (en) 2016-06-27 2016-08-10 Euremab Srl Anti met antibodiesand uses thereof
IT201800000534A1 (it) * 2018-01-03 2019-07-03 Procedimenti per la promozione della crescita cellulare degli isolotti pancreatici.
TWI770065B (zh) * 2016-09-29 2022-07-11 日商田邊三菱製藥股份有限公司 Cmet單株結合劑、其藥物複合體及其用途
TWI782930B (zh) 2016-11-16 2022-11-11 美商再生元醫藥公司 抗met抗體,結合met之雙特異性抗原結合分子及其使用方法
CN106872695B (zh) * 2017-01-20 2019-06-11 中山大学 一种h7亚型禽流感病毒血凝素抗体间接elisa检测试剂盒
IT201800000535A1 (it) 2018-01-03 2019-07-03 Procedimenti per la cura del cancro.
IT201800003875A1 (it) * 2018-03-22 2019-09-22 Metis Prec Medicine Sb S R L Nuova combinazione di agenti terapeutici per il trattamento di un tumore e/o metastasi
AU2019243764B2 (en) * 2018-03-28 2025-07-24 Mitsubishi Tanabe Pharma Corporation Drug conjugates of cMET monoclonal binding agents, and uses thereof
IT201800009282A1 (it) 2018-10-09 2020-04-09 Metis Prec Medicine Sb Srl Nuovo agente terapeutico per il trattamento di un tumore e/o metastasi
WO2021055350A1 (en) 2019-09-16 2021-03-25 Regeneron Pharmaceuticals, Inc. Radiolabeled met binding proteins for immuno-pet imaging
WO2024246356A1 (en) 2023-06-01 2024-12-05 Pierre Fabre Medicament Silenced antibody-based anti-met constructs for the treatment of tumors and metastasis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU22545A1 (es) * 1994-11-18 1999-03-31 Centro Inmunologia Molecular Obtención de un anticuerpo quimérico y humanizado contra el receptor del factor de crecimiento epidérmico para uso diagnóstico y terapéutico
US6814962B1 (en) 1994-06-02 2004-11-09 Aventis Pharma S.A. Recombinant viruses and their use for treatment of atherosclerosis and other forms of coronary artery disease and method, reagent, and kit for evaluating susceptibility to same
US6214344B1 (en) * 1995-06-02 2001-04-10 Genetech, Inc. Hepatocyte growth factor receptor antagonists and uses thereof
HN2004000285A (es) 2003-08-04 2006-04-27 Pfizer Prod Inc ANTICUERPOS DIRIGIDOS A c-MET

Similar Documents

Publication Publication Date Title
JP2009526010A5 (enExample)
KR102470294B1 (ko) 암을 치료하기 위한 항-pd1 항체 및 방사선의 조합
Jeong et al. Novel anti-4-1BB× PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockade
CN116077647B (zh) 喹啉衍生物与抗体的药物组合
US20200392239A1 (en) Use of a multimeric anti-dr5 binding molecule in combination with a chemotherapeutic agent for treating cancer
JP2010531140A5 (enExample)
CN110382532B (zh) 抗g-csf抗体及其用途
TW202045539A (zh) 抗ceacam5免疫偶聯物用於治療肺癌的用途
AU2021271647A1 (en) Use of a multimeric anti-DR5 binding molecule in combination with a cancer therapy for treating cancer
JP2018536682A (ja) Egfr及び/またはerbb3遮断に耐性のある腫瘍の成長を低減または防止するための方法
JP7422070B2 (ja) 癌の治療のための配合剤
CN105828841A (zh) 抗-efna4抗体-药物缀合物
WO2024148339A1 (en) Use of a multimeric anti-dr5 antibody for treating cancer
TW202430209A (zh) 單獨使用雙特異性EGFR x CD28抗體或其與抗PD-1抗體組合使用治療癌症之方法
CN110152014B (zh) 抗trailr2抗体-毒素-偶联物及其在抗肿瘤治疗中的药物用途
WO2025067400A1 (en) Combination of anti-claudin 18.2/anti-4-1bb antibodies and second therapeutic agent in treatment of cancer
CN106963950B (zh) 用于治疗肿瘤的联合用药物
US20250388682A1 (en) Degradation of egfr using a bispecific binding agent
Burke Targeting T-cells to Acute Myeloid Leukemia with a Novel Bispecific Antibody Format
WO2025021073A1 (zh) 抗Nectin4抗体药物偶联物和抗PD-1抗体的药物组合以及其用途
KR20230061499A (ko) Pd-1 저해제 투여에 의한 암 통증 치료 방법
KR20250029133A (ko) 암 치료를 위한 표피성장인자 수용체 티로신 키나제 억제제를 포함하는 조합물
EP4619437A2 (en) Degradation of cmet using a bispecific binding agent
JP2025526112A (ja) 二特異性結合剤を使用するegfrの分解
Stringer et al. American Society of Hematology 60th Annual Meeting and Exposition. San Diego, California, USA-December 1-4, 2018