JP2009526010A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009526010A5 JP2009526010A5 JP2008553739A JP2008553739A JP2009526010A5 JP 2009526010 A5 JP2009526010 A5 JP 2009526010A5 JP 2008553739 A JP2008553739 A JP 2008553739A JP 2008553739 A JP2008553739 A JP 2008553739A JP 2009526010 A5 JP2009526010 A5 JP 2009526010A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- monoclonal antibody
- antibody
- hgfr
- cdr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06101345.4 | 2006-02-06 | ||
| EP06101345 | 2006-02-06 | ||
| PCT/EP2007/051066 WO2007090807A1 (en) | 2006-02-06 | 2007-02-05 | Anti-met monoclonal antibody, fragments and vectors thereof, for the treatment of tumors and corresponding products |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009526010A JP2009526010A (ja) | 2009-07-16 |
| JP2009526010A5 true JP2009526010A5 (enExample) | 2010-02-25 |
| JP5306828B2 JP5306828B2 (ja) | 2013-10-02 |
Family
ID=36616994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008553739A Active JP5306828B2 (ja) | 2006-02-06 | 2007-02-05 | 腫瘍の治療のための、抗metモノクローナル抗体、フラグメント及びそのベクター、並びに対応する製品 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US8388958B2 (enExample) |
| EP (2) | EP2192188A1 (enExample) |
| JP (1) | JP5306828B2 (enExample) |
| KR (1) | KR101429297B1 (enExample) |
| CN (1) | CN101379192B (enExample) |
| AT (1) | ATE514715T1 (enExample) |
| AU (1) | AU2007213804B2 (enExample) |
| BR (1) | BRPI0707480A8 (enExample) |
| CA (1) | CA2638889C (enExample) |
| CY (1) | CY1111884T1 (enExample) |
| DK (1) | DK1981981T3 (enExample) |
| EA (1) | EA015580B1 (enExample) |
| ES (1) | ES2368864T3 (enExample) |
| IL (1) | IL192879A (enExample) |
| MX (1) | MX2008009833A (enExample) |
| PL (1) | PL1981981T3 (enExample) |
| PT (1) | PT1981981E (enExample) |
| SG (2) | SG169383A1 (enExample) |
| SI (1) | SI1981981T1 (enExample) |
| WO (1) | WO2007090807A1 (enExample) |
| ZA (1) | ZA200806559B (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2014681A1 (en) | 2007-07-12 | 2009-01-14 | Pierre Fabre Medicament | Novel antibodies inhibiting c-met dimerization, and uses thereof |
| IL198545A0 (en) | 2008-05-14 | 2011-07-31 | Metheresis Translational Res Sa | High affinity binding site of hgfr and methods for identification of antagonists thereof |
| EP2127683A1 (en) * | 2008-05-29 | 2009-12-02 | Metheresis Translational Research SA | Anti-Met monoclonal antibody, fragments and derivatives thereof for use in tumor imaging, corresponding compositions and kits |
| PA8849001A1 (es) | 2008-11-21 | 2010-06-28 | Lilly Co Eli | Anticuerpos de c-met |
| EP2287197A1 (en) * | 2009-08-21 | 2011-02-23 | Pierre Fabre Medicament | Anti-cMET antibody and its use for the detection and the diagnosis of cancer |
| KR101671378B1 (ko) * | 2009-10-30 | 2016-11-01 | 삼성전자 주식회사 | c-Met에 특이적으로 결합하는 항체 및 그의 용도 |
| KR101748707B1 (ko) | 2009-11-27 | 2017-06-20 | 삼성전자주식회사 | c-Met에 특이적으로 결합하는 항체 및 그를 이용한 암 진단용 키트 |
| KR101814571B1 (ko) | 2010-03-10 | 2018-01-04 | 젠맵 에이/에스 | C―met에 대한 모노클로날 항체 |
| WO2011125458A1 (ja) | 2010-04-02 | 2011-10-13 | 富士レビオ株式会社 | 抗癌剤の効果の診断用マーカー |
| US9169329B2 (en) * | 2010-06-01 | 2015-10-27 | Ludwig Institute For Cancer Research | Antibodies directed to the receptor tyrosine kinase c-Met |
| CA2809677A1 (en) * | 2010-09-03 | 2012-03-08 | Academia Sinica | Anti-c-met antibody and methods of use thereof |
| WO2012059561A1 (en) | 2010-11-03 | 2012-05-10 | Argen-X-Bv | Anti c-met antibodies |
| PL2500036T3 (pl) * | 2011-03-18 | 2014-10-31 | Metheresis Translational Res Sa | Inhibitory met do zwiększania skuteczności radioterapii |
| EP2758430A4 (en) | 2011-09-20 | 2015-06-03 | Lilly Co Eli | ANTI-C-MET ANTIBODY |
| WO2013064700A2 (en) | 2011-11-03 | 2013-05-10 | Argen-X B.V. | Chimeric polypeptides and methods of use |
| CN104066748A (zh) | 2011-11-21 | 2014-09-24 | 霍夫曼-拉罗奇有限公司 | 抗c-met抗体的纯化 |
| EP2785741A1 (en) | 2011-12-02 | 2014-10-08 | Cancer Research Technology Limited | Antibodies against hgf - receptor and uses |
| US8900582B2 (en) | 2011-12-22 | 2014-12-02 | Samsung Electronics Co., Ltd. | Deimmunized anti c-Met humanized antibodies and uses thereof |
| CN103382223B (zh) * | 2012-04-01 | 2015-06-10 | 上海益杰生物技术有限公司 | 针对表皮生长因子受体隐蔽表位和t细胞抗原的多功能抗体多肽 |
| CA2877573A1 (en) * | 2012-06-21 | 2013-12-27 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind c-met |
| ITTO20130012A1 (it) | 2013-01-09 | 2014-07-10 | Metheresis Translational Res S A | Nuovi frammenti anticorpali, relative composizioni ed usi |
| CN107001471B (zh) | 2014-09-16 | 2022-01-18 | 西福根有限公司 | 抗met抗体和组合物 |
| WO2016149116A1 (en) * | 2015-03-13 | 2016-09-22 | University Of Maryland, Baltimore | Antibodies targeting s100b and methods of use |
| KR20170136536A (ko) | 2015-03-16 | 2017-12-11 | 셀덱스 쎄라퓨틱스, 인크. | 항-met 항체 및 그 사용 방법 |
| GB201611123D0 (en) | 2016-06-27 | 2016-08-10 | Euremab Srl | Anti met antibodiesand uses thereof |
| IT201800000534A1 (it) * | 2018-01-03 | 2019-07-03 | Procedimenti per la promozione della crescita cellulare degli isolotti pancreatici. | |
| TWI770065B (zh) * | 2016-09-29 | 2022-07-11 | 日商田邊三菱製藥股份有限公司 | Cmet單株結合劑、其藥物複合體及其用途 |
| TWI782930B (zh) | 2016-11-16 | 2022-11-11 | 美商再生元醫藥公司 | 抗met抗體,結合met之雙特異性抗原結合分子及其使用方法 |
| CN106872695B (zh) * | 2017-01-20 | 2019-06-11 | 中山大学 | 一种h7亚型禽流感病毒血凝素抗体间接elisa检测试剂盒 |
| IT201800000535A1 (it) | 2018-01-03 | 2019-07-03 | Procedimenti per la cura del cancro. | |
| IT201800003875A1 (it) * | 2018-03-22 | 2019-09-22 | Metis Prec Medicine Sb S R L | Nuova combinazione di agenti terapeutici per il trattamento di un tumore e/o metastasi |
| AU2019243764B2 (en) * | 2018-03-28 | 2025-07-24 | Mitsubishi Tanabe Pharma Corporation | Drug conjugates of cMET monoclonal binding agents, and uses thereof |
| IT201800009282A1 (it) | 2018-10-09 | 2020-04-09 | Metis Prec Medicine Sb Srl | Nuovo agente terapeutico per il trattamento di un tumore e/o metastasi |
| WO2021055350A1 (en) | 2019-09-16 | 2021-03-25 | Regeneron Pharmaceuticals, Inc. | Radiolabeled met binding proteins for immuno-pet imaging |
| WO2024246356A1 (en) | 2023-06-01 | 2024-12-05 | Pierre Fabre Medicament | Silenced antibody-based anti-met constructs for the treatment of tumors and metastasis |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CU22545A1 (es) * | 1994-11-18 | 1999-03-31 | Centro Inmunologia Molecular | Obtención de un anticuerpo quimérico y humanizado contra el receptor del factor de crecimiento epidérmico para uso diagnóstico y terapéutico |
| US6814962B1 (en) | 1994-06-02 | 2004-11-09 | Aventis Pharma S.A. | Recombinant viruses and their use for treatment of atherosclerosis and other forms of coronary artery disease and method, reagent, and kit for evaluating susceptibility to same |
| US6214344B1 (en) * | 1995-06-02 | 2001-04-10 | Genetech, Inc. | Hepatocyte growth factor receptor antagonists and uses thereof |
| HN2004000285A (es) | 2003-08-04 | 2006-04-27 | Pfizer Prod Inc | ANTICUERPOS DIRIGIDOS A c-MET |
-
2007
- 2007-02-05 ES ES07704350T patent/ES2368864T3/es active Active
- 2007-02-05 DK DK07704350.3T patent/DK1981981T3/da active
- 2007-02-05 PT PT07704350T patent/PT1981981E/pt unknown
- 2007-02-05 CA CA2638889A patent/CA2638889C/en active Active
- 2007-02-05 AT AT07704350T patent/ATE514715T1/de active
- 2007-02-05 EA EA200870234A patent/EA015580B1/ru not_active IP Right Cessation
- 2007-02-05 KR KR1020087016543A patent/KR101429297B1/ko active Active
- 2007-02-05 CN CN2007800047097A patent/CN101379192B/zh active Active
- 2007-02-05 MX MX2008009833A patent/MX2008009833A/es active IP Right Grant
- 2007-02-05 PL PL07704350T patent/PL1981981T3/pl unknown
- 2007-02-05 SI SI200730720T patent/SI1981981T1/sl unknown
- 2007-02-05 WO PCT/EP2007/051066 patent/WO2007090807A1/en not_active Ceased
- 2007-02-05 BR BRPI0707480A patent/BRPI0707480A8/pt not_active Application Discontinuation
- 2007-02-05 SG SG201100806-7A patent/SG169383A1/en unknown
- 2007-02-05 AU AU2007213804A patent/AU2007213804B2/en active Active
- 2007-02-05 US US12/223,623 patent/US8388958B2/en active Active
- 2007-02-05 EP EP10151809A patent/EP2192188A1/en not_active Withdrawn
- 2007-02-05 EP EP07704350A patent/EP1981981B1/en active Active
- 2007-02-05 SG SG201100805-9A patent/SG169382A1/en unknown
- 2007-02-05 JP JP2008553739A patent/JP5306828B2/ja active Active
-
2008
- 2008-07-17 IL IL192879A patent/IL192879A/en active IP Right Grant
- 2008-07-28 ZA ZA2008/06559A patent/ZA200806559B/en unknown
-
2011
- 2011-09-26 CY CY20111100926T patent/CY1111884T1/el unknown
- 2011-11-04 US US13/373,101 patent/US8729043B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009526010A5 (enExample) | ||
| KR102470294B1 (ko) | 암을 치료하기 위한 항-pd1 항체 및 방사선의 조합 | |
| Jeong et al. | Novel anti-4-1BB× PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockade | |
| CN116077647B (zh) | 喹啉衍生物与抗体的药物组合 | |
| US20200392239A1 (en) | Use of a multimeric anti-dr5 binding molecule in combination with a chemotherapeutic agent for treating cancer | |
| JP2010531140A5 (enExample) | ||
| CN110382532B (zh) | 抗g-csf抗体及其用途 | |
| TW202045539A (zh) | 抗ceacam5免疫偶聯物用於治療肺癌的用途 | |
| AU2021271647A1 (en) | Use of a multimeric anti-DR5 binding molecule in combination with a cancer therapy for treating cancer | |
| JP2018536682A (ja) | Egfr及び/またはerbb3遮断に耐性のある腫瘍の成長を低減または防止するための方法 | |
| JP7422070B2 (ja) | 癌の治療のための配合剤 | |
| CN105828841A (zh) | 抗-efna4抗体-药物缀合物 | |
| WO2024148339A1 (en) | Use of a multimeric anti-dr5 antibody for treating cancer | |
| TW202430209A (zh) | 單獨使用雙特異性EGFR x CD28抗體或其與抗PD-1抗體組合使用治療癌症之方法 | |
| CN110152014B (zh) | 抗trailr2抗体-毒素-偶联物及其在抗肿瘤治疗中的药物用途 | |
| WO2025067400A1 (en) | Combination of anti-claudin 18.2/anti-4-1bb antibodies and second therapeutic agent in treatment of cancer | |
| CN106963950B (zh) | 用于治疗肿瘤的联合用药物 | |
| US20250388682A1 (en) | Degradation of egfr using a bispecific binding agent | |
| Burke | Targeting T-cells to Acute Myeloid Leukemia with a Novel Bispecific Antibody Format | |
| WO2025021073A1 (zh) | 抗Nectin4抗体药物偶联物和抗PD-1抗体的药物组合以及其用途 | |
| KR20230061499A (ko) | Pd-1 저해제 투여에 의한 암 통증 치료 방법 | |
| KR20250029133A (ko) | 암 치료를 위한 표피성장인자 수용체 티로신 키나제 억제제를 포함하는 조합물 | |
| EP4619437A2 (en) | Degradation of cmet using a bispecific binding agent | |
| JP2025526112A (ja) | 二特異性結合剤を使用するegfrの分解 | |
| Stringer et al. | American Society of Hematology 60th Annual Meeting and Exposition. San Diego, California, USA-December 1-4, 2018 |