PL1981981T3 - Przeciwciało monoklonalne anty-Met, jego fragmenty i wektory do leczenia nowotworów oraz odpowiednie produkty - Google Patents
Przeciwciało monoklonalne anty-Met, jego fragmenty i wektory do leczenia nowotworów oraz odpowiednie produktyInfo
- Publication number
- PL1981981T3 PL1981981T3 PL07704350T PL07704350T PL1981981T3 PL 1981981 T3 PL1981981 T3 PL 1981981T3 PL 07704350 T PL07704350 T PL 07704350T PL 07704350 T PL07704350 T PL 07704350T PL 1981981 T3 PL1981981 T3 PL 1981981T3
- Authority
- PL
- Poland
- Prior art keywords
- monoclonal antibody
- tumors
- vectors
- treatment
- met monoclonal
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 title abstract 2
- 239000013598 vector Substances 0.000 title abstract 2
- 102000003745 Hepatocyte Growth Factor Human genes 0.000 abstract 1
- 108090000100 Hepatocyte Growth Factor Proteins 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940043355 kinase inhibitor Drugs 0.000 abstract 1
- 210000005170 neoplastic cell Anatomy 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/867—Retroviral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06101345 | 2006-02-06 | ||
| EP07704350A EP1981981B1 (en) | 2006-02-06 | 2007-02-05 | Anti-met monoclonal antibody, fragments and vectors thereof, for the treatment of tumors and corresponding products |
| PCT/EP2007/051066 WO2007090807A1 (en) | 2006-02-06 | 2007-02-05 | Anti-met monoclonal antibody, fragments and vectors thereof, for the treatment of tumors and corresponding products |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1981981T3 true PL1981981T3 (pl) | 2011-11-30 |
Family
ID=36616994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07704350T PL1981981T3 (pl) | 2006-02-06 | 2007-02-05 | Przeciwciało monoklonalne anty-Met, jego fragmenty i wektory do leczenia nowotworów oraz odpowiednie produkty |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US8388958B2 (pl) |
| EP (2) | EP2192188A1 (pl) |
| JP (1) | JP5306828B2 (pl) |
| KR (1) | KR101429297B1 (pl) |
| CN (1) | CN101379192B (pl) |
| AT (1) | ATE514715T1 (pl) |
| AU (1) | AU2007213804B2 (pl) |
| BR (1) | BRPI0707480A8 (pl) |
| CA (1) | CA2638889C (pl) |
| CY (1) | CY1111884T1 (pl) |
| DK (1) | DK1981981T3 (pl) |
| EA (1) | EA015580B1 (pl) |
| ES (1) | ES2368864T3 (pl) |
| IL (1) | IL192879A (pl) |
| MX (1) | MX2008009833A (pl) |
| PL (1) | PL1981981T3 (pl) |
| PT (1) | PT1981981E (pl) |
| SG (2) | SG169383A1 (pl) |
| SI (1) | SI1981981T1 (pl) |
| WO (1) | WO2007090807A1 (pl) |
| ZA (1) | ZA200806559B (pl) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2014681A1 (en) | 2007-07-12 | 2009-01-14 | Pierre Fabre Medicament | Novel antibodies inhibiting c-met dimerization, and uses thereof |
| IL198545A0 (en) * | 2008-05-14 | 2011-07-31 | Metheresis Translational Res Sa | High affinity binding site of hgfr and methods for identification of antagonists thereof |
| EP2127683A1 (en) * | 2008-05-29 | 2009-12-02 | Metheresis Translational Research SA | Anti-Met monoclonal antibody, fragments and derivatives thereof for use in tumor imaging, corresponding compositions and kits |
| PA8849001A1 (es) | 2008-11-21 | 2010-06-28 | Lilly Co Eli | Anticuerpos de c-met |
| EP2287197A1 (en) * | 2009-08-21 | 2011-02-23 | Pierre Fabre Medicament | Anti-cMET antibody and its use for the detection and the diagnosis of cancer |
| KR101671378B1 (ko) | 2009-10-30 | 2016-11-01 | 삼성전자 주식회사 | ｃ-Ｍｅｔ에 특이적으로 결합하는 항체 및 그의 용도 |
| KR101748707B1 (ko) * | 2009-11-27 | 2017-06-20 | 삼성전자주식회사 | ｃ-Ｍｅｔ에 특이적으로 결합하는 항체 및 그를 이용한 암 진단용 키트 |
| CN103003307B (zh) | 2010-03-10 | 2017-08-11 | 根马布股份公司 | 抗c‑MEt的单克隆抗体 |
| WO2011125458A1 (ja) * | 2010-04-02 | 2011-10-13 | 富士レビオ株式会社 | 抗癌剤の効果の診断用マーカー |
| AU2011261161A1 (en) * | 2010-06-01 | 2013-01-10 | Ludwig Institute For Cancer Research Limited | Antibodies directed to the unprocessed receptor tyrosine kinase c-Met |
| KR20140019284A (ko) * | 2010-09-03 | 2014-02-14 | 아카데미아 시니카 | 항-C-Met 항체 및 이의 이용 방법들 |
| EP3165538A1 (en) | 2010-11-03 | 2017-05-10 | Argen-X Nv | Anti c-met antibodies |
| EP2500036B1 (en) * | 2011-03-18 | 2014-05-07 | Metheresis Translational Research SA | MET inhibitors for enhancing radiotherapy efficacy |
| WO2013043452A1 (en) | 2011-09-20 | 2013-03-28 | Eli Lilly And Company | Anti-c-met antibodies |
| EP2773660A2 (en) | 2011-11-03 | 2014-09-10 | Argen-X B.V. | Chimeric human-camel antigens and their use |
| US20130129718A1 (en) | 2011-11-21 | 2013-05-23 | Genentech, Inc. | Purification of anti-c-met antibodies |
| EP2785741A1 (en) | 2011-12-02 | 2014-10-08 | Cancer Research Technology Limited | Antibodies against hgf - receptor and uses |
| US8900582B2 (en) | 2011-12-22 | 2014-12-02 | Samsung Electronics Co., Ltd. | Deimmunized anti c-Met humanized antibodies and uses thereof |
| CN103382223B (zh) * | 2012-04-01 | 2015-06-10 | 上海益杰生物技术有限公司 | 针对表皮生长因子受体隐蔽表位和t细胞抗原的多功能抗体多肽 |
| US10377827B2 (en) * | 2012-06-21 | 2019-08-13 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind c-met |
| ITTO20130012A1 (it) | 2013-01-09 | 2014-07-10 | Metheresis Translational Res S A | Nuovi frammenti anticorpali, relative composizioni ed usi |
| IL250902B (en) | 2014-09-16 | 2022-08-01 | Symphogen As | Anti-met antibodies and compositions |
| WO2016149116A1 (en) * | 2015-03-13 | 2016-09-22 | University Of Maryland, Baltimore | Antibodies targeting s100b and methods of use |
| WO2016149265A1 (en) * | 2015-03-16 | 2016-09-22 | Kolltan Pharmaceuticals, Inc. | Anti-met antibodies and methods of use thereof |
| GB201611123D0 (en) | 2016-06-27 | 2016-08-10 | Euremab Srl | Anti met antibodiesand uses thereof |
| IT201800000534A1 (it) * | 2018-01-03 | 2019-07-03 | Procedimenti per la promozione della crescita cellulare degli isolotti pancreatici. | |
| CN116731177A (zh) | 2016-09-29 | 2023-09-12 | 田边三菱制药株式会社 | cMET单克隆结合剂、其药物缀合物及其用途 |
| TWI782930B (zh) | 2016-11-16 | 2022-11-11 | 美商再生元醫藥公司 | 抗ｍｅｔ抗體，結合ｍｅｔ之雙特異性抗原結合分子及其使用方法 |
| CN106872695B (zh) * | 2017-01-20 | 2019-06-11 | 中山大学 | 一种h7亚型禽流感病毒血凝素抗体间接elisa检测试剂盒 |
| IT201800000535A1 (it) | 2018-01-03 | 2019-07-03 | Procedimenti per la cura del cancro. | |
| IT201800003875A1 (it) | 2018-03-22 | 2019-09-22 | Metis Prec Medicine Sb S R L | Nuova combinazione di agenti terapeutici per il trattamento di un tumore e/o metastasi |
| KR20200138288A (ko) * | 2018-03-28 | 2020-12-09 | 미쓰비시 타나베 파마 코퍼레이션 | cMET 모노클로날 결합제의 약물 접합체, 및 그의 용도 |
| IT201800009282A1 (it) | 2018-10-09 | 2020-04-09 | Metis Prec Medicine Sb Srl | Nuovo agente terapeutico per il trattamento di un tumore e/o metastasi |
| KR20220063185A (ko) | 2019-09-16 | 2022-05-17 | 리제너론 파마슈티칼스 인코포레이티드 | 면역-pet 영상화를 위한 방사성 표지된 met 결합 단백질 |
| WO2024246356A1 (en) | 2023-06-01 | 2024-12-05 | Pierre Fabre Medicament | Silenced antibody-based anti-met constructs for the treatment of tumors and metastasis |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CU22545A1 (es) * | 1994-11-18 | 1999-03-31 | Centro Inmunologia Molecular | Obtención de un anticuerpo quimérico y humanizado contra el receptor del factor de crecimiento epidérmico para uso diagnóstico y terapéutico |
| US6814962B1 (en) | 1994-06-02 | 2004-11-09 | Aventis Pharma S.A. | Recombinant viruses and their use for treatment of atherosclerosis and other forms of coronary artery disease and method, reagent, and kit for evaluating susceptibility to same |
| US6214344B1 (en) | 1995-06-02 | 2001-04-10 | Genetech, Inc. | Hepatocyte growth factor receptor antagonists and uses thereof |
| HN2004000285A (es) * | 2003-08-04 | 2006-04-27 | Pfizer Prod Inc | ANTICUERPOS DIRIGIDOS A c-MET |
-
2007
- 2007-02-05 KR KR1020087016543A patent/KR101429297B1/ko active Active
- 2007-02-05 SG SG201100806-7A patent/SG169383A1/en unknown
- 2007-02-05 BR BRPI0707480A patent/BRPI0707480A8/pt not_active Application Discontinuation
- 2007-02-05 US US12/223,623 patent/US8388958B2/en active Active
- 2007-02-05 MX MX2008009833A patent/MX2008009833A/es active IP Right Grant
- 2007-02-05 PT PT07704350T patent/PT1981981E/pt unknown
- 2007-02-05 EP EP10151809A patent/EP2192188A1/en not_active Withdrawn
- 2007-02-05 SI SI200730720T patent/SI1981981T1/sl unknown
- 2007-02-05 JP JP2008553739A patent/JP5306828B2/ja active Active
- 2007-02-05 WO PCT/EP2007/051066 patent/WO2007090807A1/en not_active Ceased
- 2007-02-05 AU AU2007213804A patent/AU2007213804B2/en active Active
- 2007-02-05 CA CA2638889A patent/CA2638889C/en active Active
- 2007-02-05 CN CN2007800047097A patent/CN101379192B/zh active Active
- 2007-02-05 EP EP07704350A patent/EP1981981B1/en active Active
- 2007-02-05 AT AT07704350T patent/ATE514715T1/de active
- 2007-02-05 EA EA200870234A patent/EA015580B1/ru not_active IP Right Cessation
- 2007-02-05 ES ES07704350T patent/ES2368864T3/es active Active
- 2007-02-05 SG SG201100805-9A patent/SG169382A1/en unknown
- 2007-02-05 PL PL07704350T patent/PL1981981T3/pl unknown
- 2007-02-05 DK DK07704350.3T patent/DK1981981T3/da active
-
2008
- 2008-07-17 IL IL192879A patent/IL192879A/en active IP Right Grant
- 2008-07-28 ZA ZA2008/06559A patent/ZA200806559B/en unknown
-
2011
- 2011-09-26 CY CY20111100926T patent/CY1111884T1/el unknown
- 2011-11-04 US US13/373,101 patent/US8729043B2/en active Active
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