|
US5585344A
(en)
*
|
1984-03-19 |
1996-12-17 |
The Rockefeller University |
Liver-derived receptors for advanced glycosylation endproducts and uses thereof
|
|
US4774321A
(en)
*
|
1986-12-01 |
1988-09-27 |
Massachusetts Institute Of Technology |
DP100 EGF and insulin-binding protein from Drosophila cells
|
|
AU627423B2
(en)
|
1987-04-06 |
1992-08-27 |
Celtrix Pharmaceuticals, Inc. |
Human somatomedin carrier protein subunits and process for producing them
|
|
US5200509A
(en)
*
|
1987-04-06 |
1993-04-06 |
Celtrix Pharmaceuticals, Inc. |
Human somatomedin carrier protein subunits and process for producing them; recombinant DNA molecules, hosts, processes and human somatomedin carrier protein-like polypeptides
|
|
WO1989006692A1
(en)
|
1988-01-12 |
1989-07-27 |
Genentech, Inc. |
Method of treating tumor cells by inhibiting growth factor receptor function
|
|
GB8826451D0
(en)
|
1988-11-11 |
1988-12-14 |
Sandoz Ltd |
Improvements in/relating to organic compounds
|
|
US5571714A
(en)
*
|
1988-12-22 |
1996-11-05 |
Celtrix Pharmaceuticals, Inc. |
Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use
|
|
IL92816A0
(en)
|
1988-12-22 |
1990-09-17 |
Biogrowth Inc |
Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides
|
|
US5705157A
(en)
*
|
1989-07-27 |
1998-01-06 |
The Trustees Of The University Of Pennsylvania |
Methods of treating cancerous cells with anti-receptor antibodies
|
|
US5977307A
(en)
*
|
1989-09-07 |
1999-11-02 |
Alkermes, Inc. |
Transferrin receptor specific ligand-neuropharmaceutical agent fusion proteins
|
|
WO1992003152A1
(en)
*
|
1990-08-28 |
1992-03-05 |
Chiron Corporation |
New insulin-like growth factor binding protein (igfbp-4)
|
|
AU661533B2
(en)
|
1992-01-20 |
1995-07-27 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
US5262308A
(en)
*
|
1992-01-28 |
1993-11-16 |
Thomas Jefferson University |
Cell lines which constitutively express IGF-1 and IGF-1 R
|
|
US5597563A
(en)
*
|
1992-09-04 |
1997-01-28 |
Beschorner; William E. |
Method induction of antigen-specific immune tolerance
|
|
US5869337A
(en)
*
|
1993-02-12 |
1999-02-09 |
President And Fellows Of Harvard College |
Regulated transcription of targeted genes and other biological events
|
|
JPH08508409A
(ja)
*
|
1993-04-06 |
1996-09-10 |
シーダーズ − サイナイ メディカル センター |
変異インスリン様増殖因子▲ｉ▼受容体サブユニットおよびそれらの使用方法
|
|
AU1518595A
(en)
*
|
1994-01-14 |
1995-08-01 |
Genentech Inc. |
Antagonists to insulin receptor tyrosine kinase inhibitor
|
|
US5532159A
(en)
*
|
1994-04-01 |
1996-07-02 |
The Ohio State University |
Monoclonal antibody to canine placental oncofetal protein for detecting cancer
|
|
US5597700A
(en)
*
|
1994-04-28 |
1997-01-28 |
California Research, Llc |
Method for detecting free insulin-like growth-factor-binding protein 1 and a test device for detecting the ruptures of fetal membranes using the above method
|
|
WO1996000084A1
(en)
*
|
1994-06-24 |
1996-01-04 |
Torchilin Vladimir P |
Use of autoantibodies for tumor therapy and prophylaxis
|
|
US5939269A
(en)
*
|
1994-12-28 |
1999-08-17 |
The Regents Of The University Of California |
Antagonists to insulin receptor tyrosine kinase inhibitor
|
|
MX9707453A
(es)
|
1995-03-30 |
1997-12-31 |
Pfizer |
Derivados de quinazolina.
|
|
AU6267896A
(en)
|
1995-06-07 |
1996-12-30 |
Imclone Systems Incorporated |
Antibody and antibody fragments for inhibiting the growth oftumors
|
|
EP0861267A4
(en)
*
|
1995-11-14 |
2000-02-02 |
Univ Jefferson |
INDUCTION AND RESISTANCE TO TUMOR GROWTH BY MEANS OF SOLUBLE IGF-1
|
|
AUPN999096A0
(en)
|
1996-05-22 |
1996-06-13 |
Northstar Biologicals Pty Ltd |
Peptides, antibodies, vaccines & uses thereof
|
|
US5798266A
(en)
*
|
1996-08-27 |
1998-08-25 |
K-Quay Enterprises, Llc |
Methods and kits for obtaining and assaying mammary fluid samples for breast diseases, including cancer
|
|
US6071891A
(en)
*
|
1996-11-22 |
2000-06-06 |
Regents Of The University Of Minnesota |
Insulin-like growth factor 1 receptors (IGF-1R) antisense oligonucleotide cells composition
|
|
US5968895A
(en)
*
|
1996-12-11 |
1999-10-19 |
Praecis Pharmaceuticals, Inc. |
Pharmaceutical formulations for sustained drug delivery
|
|
TR200000415T2
(tr)
*
|
1997-08-15 |
2000-08-21 |
Cephalon Inc. |
Prostat kanserinin tedavi edilmesi için birleşimler.
|
|
ZA200007412B
(en)
*
|
1998-05-15 |
2002-03-12 |
Imclone Systems Inc |
Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases.
|
|
US6875741B2
(en)
*
|
1998-09-02 |
2005-04-05 |
Renuka Pillutla |
Insulin and IGF-1 receptor agonists and antagonists
|
|
IL141868A0
(en)
*
|
1998-10-05 |
2002-03-10 |
M & E Biotech As |
Novel methods for therapeutic vaccination
|
|
EP1006184A1
(en)
*
|
1998-12-03 |
2000-06-07 |
F. Hoffmann-La Roche Ag |
IGF-1 receptor interacting proteins (IIPs) genes coding therefor and uses thereof
|
|
US6316462B1
(en)
*
|
1999-04-09 |
2001-11-13 |
Schering Corporation |
Methods of inducing cancer cell death and tumor regression
|
|
EP1299419A2
(en)
|
2000-05-24 |
2003-04-09 |
Imclone Systems, Inc. |
Bispecific immunoglobulin-like antigen binding proteins and method of production
|
|
US7329745B2
(en)
*
|
2000-06-13 |
2008-02-12 |
City Of Hope |
Single-chain antibodies against human insulin-like growth factor I receptor: expression, purification, and effect on tumor growth
|
|
US20030165502A1
(en)
*
|
2000-06-13 |
2003-09-04 |
City Of Hope |
Single-chain antibodies against human insulin-like growth factor I receptor: expression, purification, and effect on tumor growth
|
|
WO2001098493A1
(en)
*
|
2000-06-15 |
2001-12-27 |
Kyowa Hakko Kogyo Co., Ltd |
Insulin-like growth factor-binding protein
|
|
US8153121B2
(en)
*
|
2000-10-06 |
2012-04-10 |
Los Angeles Biomedical Research Institute at Harbor—UCLA Medical Center |
Diagnosis and therapy of antibody-mediated inflammatory autoimmune disorders
|
|
BRPI0116728B1
(pt)
|
2001-01-05 |
2018-10-30 |
Pfizer Inc. |
anticorpos para receptor de fator de crescimento i semelhante à insulina
|
|
US7071300B2
(en)
*
|
2001-03-14 |
2006-07-04 |
Genentech, Inc. |
IGF antagonist peptides
|
|
US20040116330A1
(en)
*
|
2001-04-27 |
2004-06-17 |
Kenichiro Naito |
Preventive/therapeutic method for cancer
|
|
US7666414B2
(en)
*
|
2001-06-01 |
2010-02-23 |
Cornell Research Foundation, Inc. |
Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen
|
|
US20040214898A1
(en)
*
|
2001-11-29 |
2004-10-28 |
Steiner Mitchell S. |
Methods for treating hot flashes
|
|
DE60312639T2
(de)
|
2002-01-18 |
2007-11-29 |
Pierre Fabre Médicament |
Antikörper gegen igf-ir und ihre verwendungen
|
|
US7553485B2
(en)
*
|
2002-01-18 |
2009-06-30 |
Pierre Fabre Medicament |
Anti-IGF-IR and/or anti-insulin/IGF-I hybrid receptors antibodies and uses thereof
|
|
US7241444B2
(en)
*
|
2002-01-18 |
2007-07-10 |
Pierre Fabre Medicament |
Anti-IGF-IR antibodies and uses thereof
|
|
US7217796B2
(en)
|
2002-05-24 |
2007-05-15 |
Schering Corporation |
Neutralizing human anti-IGFR antibody
|
|
US7538195B2
(en)
|
2002-06-14 |
2009-05-26 |
Immunogen Inc. |
Anti-IGF-I receptor antibody
|
|
US8034904B2
(en)
*
|
2002-06-14 |
2011-10-11 |
Immunogen Inc. |
Anti-IGF-I receptor antibody
|
|
ES2263984T3
(es)
*
|
2002-06-28 |
2006-12-16 |
Domantis Limited |
Ligandos doble-especificos con una vida media serica aumentada.
|
|
CA2494310A1
(en)
*
|
2002-08-01 |
2004-02-12 |
Immunomedics, Inc. |
Alpha-fetoprotein immu31 antibodies and fusion proteins and methods of use thereof
|
|
US20040102360A1
(en)
*
|
2002-10-30 |
2004-05-27 |
Barnett Stanley F. |
Combination therapy
|
|
AU2004212344B2
(en)
*
|
2003-02-13 |
2009-05-07 |
Pfizer Products Inc. |
Uses of anti-insulin-like growth factor I receptor antibodies
|
|
WO2004083248A1
(en)
|
2003-03-14 |
2004-09-30 |
Pharmacia Corporation |
Antibodies to igf-i receptor for the treatment of cancers
|
|
EP1613658B1
(en)
|
2003-04-02 |
2012-03-14 |
F. Hoffmann-La Roche AG |
Antibodies against insulin-like growth factor i receptor and uses thereof
|
|
WO2005016970A2
(en)
*
|
2003-05-01 |
2005-02-24 |
Imclone Systems Incorporated |
Fully human antibodies directed against the human insulin-like growth factor-1 receptor
|
|
AR046071A1
(es)
*
|
2003-07-10 |
2005-11-23 |
Hoffmann La Roche |
Anticuerpos contra el receptor i del factor de crecimiento de tipo insulinico y los usos de los mismos
|
|
US20050079184A1
(en)
*
|
2003-08-08 |
2005-04-14 |
Immunomedics, Inc. |
Bispecific antibodies for inducing apoptosis of tumor and diseased cells
|
|
MXPA06001634A
(es)
*
|
2003-08-13 |
2006-04-28 |
Pfizer Prod Inc |
Anticuerpos humanos modificados igf-1r.
|
|
WO2005027970A1
(ja)
*
|
2003-09-24 |
2005-03-31 |
Kyowa Hakko Kogyo Co., Ltd. |
癌治療用医薬
|
|
PE20050928A1
(es)
*
|
2003-11-21 |
2005-11-08 |
Schering Corp |
Combinaciones terapeuticas de anticuerpo anti-igfr1
|
|
US20050164970A1
(en)
*
|
2003-12-22 |
2005-07-28 |
University Of Kansas Medical Center |
Method for treating prostate cancer using siRNA duplex for androgen receptor
|
|
ATE514434T1
(de)
|
2004-02-25 |
2011-07-15 |
Dana Farber Cancer Inst Inc |
Hemmer des insulinartigen wachstumsfaktor- rezeptors-1 zur hemmung von tumorzellwachstum
|
|
EP2332990A1
(en)
|
2004-03-19 |
2011-06-15 |
Imclone LLC |
Human anti-epidermal growth factor receptor antibody
|
|
KR20070036130A
(ko)
|
2004-07-16 |
2007-04-02 |
화이자 프로덕츠 인코포레이티드 |
항-아이지에프-1알 항체를 사용하는 비-혈액학적악성종양에 대한 조합 치료
|
|
JP2008512352A
(ja)
|
2004-07-17 |
2008-04-24 |
イムクローン システムズ インコーポレイティド |
新規な四価の二重特異性抗体
|
|
FR2873699B1
(fr)
|
2004-07-29 |
2009-08-21 |
Pierre Fabre Medicament Sa |
Nouveaux anticorps anti igf ir rt leurs utilisations
|
|
US20070010537A1
(en)
*
|
2004-08-20 |
2007-01-11 |
Kazumasa Hamamura |
Fused pyramidine derivative and use thereof
|
|
EP2283831A3
(en)
|
2004-12-03 |
2013-10-23 |
Merck Sharp & Dohme Corp. |
Biomakers for pre-selection of patients for anti-IGF1R therapy
|
|
US20060134172A1
(en)
*
|
2004-12-21 |
2006-06-22 |
Alcon, Inc. |
Agents which regulate, inhibit, or modulate the activity and/or expression of lysyl oxidase (LOX) and LOX-like proteases as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies
|
|
MY146381A
(en)
|
2004-12-22 |
2012-08-15 |
Amgen Inc |
Compositions and methods relating relating to anti-igf-1 receptor antibodies
|
|
EA200702239A1
(ru)
*
|
2005-04-15 |
2008-10-30 |
Иммьюноджен, Инк. |
Уничтожение гетерогенной или смешанной клеточной популяции в опухолях
|
|
CA2612449A1
(en)
*
|
2005-06-17 |
2006-12-28 |
Imclone Systems Incorporated |
Receptor antagonists for treatment of metastatic bone cancer
|
|
WO2007000328A1
(en)
|
2005-06-27 |
2007-01-04 |
Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa |
Antibodies that bind to an epitope on insulin-like growth factor 1 receptor and uses thereof
|
|
US20070009970A1
(en)
*
|
2005-07-08 |
2007-01-11 |
Predicant Biosciences, Inc. |
Biological patterns for diagnosis and treatment of cancer
|
|
FR2888850B1
(fr)
|
2005-07-22 |
2013-01-11 |
Pf Medicament |
Nouveaux anticorps anti-igf-ir et leurs applications
|
|
CA2619298C
(en)
|
2005-08-26 |
2017-07-04 |
Glycart Biotechnology Ag |
Modified antigen binding molecules with altered cell signaling activity
|
|
ES2385054T3
(es)
*
|
2005-12-13 |
2012-07-17 |
Medimmune Limited |
Proteínas de unión específicas para factores de crecimiento de tipo insulina y usos de las mismas
|