CA2641310C - Igf-ir antagonists as adjuvants for treatment of prostate cancer - Google Patents

Igf-ir antagonists as adjuvants for treatment of prostate cancer Download PDF

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Publication number
CA2641310C
CA2641310C CA2641310A CA2641310A CA2641310C CA 2641310 C CA2641310 C CA 2641310C CA 2641310 A CA2641310 A CA 2641310A CA 2641310 A CA2641310 A CA 2641310A CA 2641310 C CA2641310 C CA 2641310C
Authority
CA
Canada
Prior art keywords
androgen
igf
deprivation therapy
imc
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2641310A
Other languages
English (en)
French (fr)
Other versions
CA2641310A1 (en
Inventor
Dale Ludwig
Stephen R. Plymate
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
ImClone LLC
Original Assignee
University of Washington
ImClone LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington, ImClone LLC filed Critical University of Washington
Publication of CA2641310A1 publication Critical patent/CA2641310A1/en
Application granted granted Critical
Publication of CA2641310C publication Critical patent/CA2641310C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2641310A 2006-02-03 2007-02-03 Igf-ir antagonists as adjuvants for treatment of prostate cancer Expired - Fee Related CA2641310C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76507206P 2006-02-03 2006-02-03
US60/765,072 2006-02-03
PCT/US2007/003164 WO2007092453A2 (en) 2006-02-03 2007-02-03 Igf-ir antagonists as adjuvants for treatment of prostate cancer

Publications (2)

Publication Number Publication Date
CA2641310A1 CA2641310A1 (en) 2007-08-16
CA2641310C true CA2641310C (en) 2013-08-20

Family

ID=38345750

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2641310A Expired - Fee Related CA2641310C (en) 2006-02-03 2007-02-03 Igf-ir antagonists as adjuvants for treatment of prostate cancer

Country Status (17)

Country Link
US (1) US7972600B2 (https=)
EP (1) EP1984011A4 (https=)
JP (1) JP5198289B2 (https=)
KR (1) KR101353706B1 (https=)
CN (1) CN101484587B (https=)
AP (1) AP2008004569A0 (https=)
AU (1) AU2007212447B2 (https=)
CA (1) CA2641310C (https=)
CR (1) CR10188A (https=)
EA (1) EA017265B1 (https=)
EC (1) ECSP088706A (https=)
IL (1) IL193203A0 (https=)
MX (1) MX2008009977A (https=)
NO (1) NO20083444L (https=)
UA (1) UA95945C2 (https=)
WO (1) WO2007092453A2 (https=)
ZA (1) ZA200807012B (https=)

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US9532972B2 (en) * 2012-02-07 2017-01-03 University Of Central Florida Research Foundation, Inc. Increasing taxane sensitivity in cancer cells
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AU2016232223A1 (en) * 2015-03-16 2017-08-31 University Of Washington Materials and methods for detecting androgen receptor splice variants and uses thereof
WO2021113794A1 (en) * 2019-12-06 2021-06-10 H. Lee Moffitt Cancer Center And Research Institute, Inc. Clinical decision support for personalized adaptive prostate cancer therapy
CN113512116B (zh) 2020-04-10 2022-09-20 苏州普乐康医药科技有限公司 一种抗igf-1r抗体及其应用
TW202434307A (zh) 2023-01-18 2024-09-01 大陸商泰勵生物科技（上海）有限公司 抗體偶聯藥物及其用途

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Also Published As

Publication number Publication date
CN101484587B (zh) 2014-02-12
EP1984011A2 (en) 2008-10-29
JP2009525348A (ja) 2009-07-09
US7972600B2 (en) 2011-07-05
AP2008004569A0 (en) 2008-08-31
UA95945C2 (ru) 2011-09-26
AU2007212447A1 (en) 2007-08-16
AU2007212447B2 (en) 2013-02-21
EA017265B1 (ru) 2012-11-30
CN101484587A (zh) 2009-07-15
MX2008009977A (es) 2009-02-27
KR20080090566A (ko) 2008-10-08
ZA200807012B (en) 2009-12-30
IL193203A0 (en) 2009-08-03
ECSP088706A (es) 2008-10-31
EA200870231A1 (ru) 2009-12-30
KR101353706B1 (ko) 2014-02-18
CR10188A (es) 2008-11-18
WO2007092453A2 (en) 2007-08-16
EP1984011A4 (en) 2010-08-18
WO2007092453A3 (en) 2008-12-24
CA2641310A1 (en) 2007-08-16
JP5198289B2 (ja) 2013-05-15
US20090175868A1 (en) 2009-07-09
NO20083444L (no) 2008-10-31

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