JP2009521239A5 - - Google Patents
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- JP2009521239A5 JP2009521239A5 JP2008547868A JP2008547868A JP2009521239A5 JP 2009521239 A5 JP2009521239 A5 JP 2009521239A5 JP 2008547868 A JP2008547868 A JP 2008547868A JP 2008547868 A JP2008547868 A JP 2008547868A JP 2009521239 A5 JP2009521239 A5 JP 2009521239A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- formula
- halopent
- sequence
- esterase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 229920001184 polypeptide Polymers 0.000 claims description 19
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- 102000004196 processed proteins & peptides Human genes 0.000 claims description 19
- -1 phosphate ester Chemical class 0.000 claims description 18
- 229910019142 PO4 Inorganic materials 0.000 claims description 17
- 239000010452 phosphate Substances 0.000 claims description 17
- 239000000203 mixture Substances 0.000 claims description 13
- 238000000034 method Methods 0.000 claims description 12
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- 125000000217 alkyl group Chemical group 0.000 claims description 11
- 239000012038 nucleophile Substances 0.000 claims description 11
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- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims description 7
- 229910052794 bromium Inorganic materials 0.000 claims description 7
- 125000001309 chloro group Chemical group Cl* 0.000 claims description 7
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 6
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- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 5
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- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims description 2
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- 239000006228 supernatant Substances 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000003799 water insoluble solvent Substances 0.000 description 1
- 239000003021 water soluble solvent Substances 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
- 239000007222 ypd medium Substances 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ATA2081/2005 | 2005-12-27 | ||
| AT0208105A AT502990A1 (de) | 2005-12-27 | 2005-12-27 | Neues polypeptid mit esteraseaktivität, und rekombinante esterase sowie deren verwendung |
| PCT/EP2006/011832 WO2007073845A2 (en) | 2005-12-27 | 2006-12-08 | Polypeptide having esterase activity and recombinant esterase and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009521239A JP2009521239A (ja) | 2009-06-04 |
| JP2009521239A5 true JP2009521239A5 (enExample) | 2012-07-26 |
| JP5119166B2 JP5119166B2 (ja) | 2013-01-16 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008547868A Expired - Fee Related JP5119166B2 (ja) | 2005-12-27 | 2006-12-08 | エステラーゼ活性を有する新規なポリペプチドおよび組換えエステラーゼ、並びに、それらの使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8158393B2 (enExample) |
| EP (1) | EP1966373B1 (enExample) |
| JP (1) | JP5119166B2 (enExample) |
| KR (1) | KR101388391B1 (enExample) |
| CN (1) | CN101351548B (enExample) |
| AT (2) | AT502990A1 (enExample) |
| BR (1) | BRPI0621280A8 (enExample) |
| CA (1) | CA2635380C (enExample) |
| ES (1) | ES2383702T3 (enExample) |
| IL (1) | IL192400A (enExample) |
| NO (1) | NO343225B1 (enExample) |
| PL (1) | PL1966373T3 (enExample) |
| SG (1) | SG170757A1 (enExample) |
| WO (1) | WO2007073845A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2171061T3 (pl) * | 2007-07-04 | 2019-03-29 | Patheon Austria Gmbh & Co Kg | Preparat esterazy |
| ES2689941T3 (es) * | 2009-04-24 | 2018-11-16 | Patheon Austria Gmbh & Co Kg | Esterasas de hígado de cerdo mejoradas |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5817490A (en) * | 1996-05-17 | 1998-10-06 | Eastman Chemical Company | Enzymatic process for the manufacture of ascorbic acid 2-keto-L-gulonic acid and esters of 2-keto-L-gulonic acid |
| DE10061864A1 (de) | 2000-12-12 | 2002-07-11 | Aventis Res & Tech Gmbh & Co | Rekombinante Schweineleberesterase, deren Verwendung sowie ein Verfahren zu deren Herstellung |
| DE10258327A1 (de) * | 2002-12-13 | 2004-06-24 | Degussa Ag | Artifizielle Esterasen |
-
2005
- 2005-12-27 AT AT0208105A patent/AT502990A1/de not_active Application Discontinuation
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2006
- 2006-12-08 US US12/159,547 patent/US8158393B2/en not_active Expired - Fee Related
- 2006-12-08 KR KR1020087018341A patent/KR101388391B1/ko not_active Expired - Fee Related
- 2006-12-08 SG SG201102064-1A patent/SG170757A1/en unknown
- 2006-12-08 EP EP06829433A patent/EP1966373B1/en not_active Not-in-force
- 2006-12-08 PL PL06829433T patent/PL1966373T3/pl unknown
- 2006-12-08 BR BRPI0621280A patent/BRPI0621280A8/pt not_active Application Discontinuation
- 2006-12-08 WO PCT/EP2006/011832 patent/WO2007073845A2/en not_active Ceased
- 2006-12-08 AT AT06829433T patent/ATE549400T1/de active
- 2006-12-08 CN CN200680049665.5A patent/CN101351548B/zh not_active Expired - Fee Related
- 2006-12-08 ES ES06829433T patent/ES2383702T3/es active Active
- 2006-12-08 CA CA2635380A patent/CA2635380C/en active Active
- 2006-12-08 JP JP2008547868A patent/JP5119166B2/ja not_active Expired - Fee Related
-
2008
- 2008-06-23 IL IL192400A patent/IL192400A/en active IP Right Grant
- 2008-06-27 NO NO20082864A patent/NO343225B1/no not_active IP Right Cessation
-
2012
- 2012-03-12 US US13/417,734 patent/US8642312B2/en active Active
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