JP2009520754A5 - - Google Patents
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- Publication number
- JP2009520754A5 JP2009520754A5 JP2008546388A JP2008546388A JP2009520754A5 JP 2009520754 A5 JP2009520754 A5 JP 2009520754A5 JP 2008546388 A JP2008546388 A JP 2008546388A JP 2008546388 A JP2008546388 A JP 2008546388A JP 2009520754 A5 JP2009520754 A5 JP 2009520754A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- tumor
- hydrogen
- leukemia
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 4
- 102000003915 DNA Topoisomerases Human genes 0.000 claims 3
- 108090000323 DNA Topoisomerases Proteins 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 229940079593 drug Drugs 0.000 claims 3
- 230000001747 exhibiting effect Effects 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 206010000871 Acute monocytic leukaemia Diseases 0.000 claims 1
- 208000031261 Acute myeloid leukaemia Diseases 0.000 claims 1
- 208000036762 Acute promyelocytic leukaemia Diseases 0.000 claims 1
- 208000018084 Bone neoplasm Diseases 0.000 claims 1
- KLWPJMFMVPTNCC-UHFFFAOYSA-N Camptothecin Natural products CCC1(O)C(=O)OCC2=C1C=C3C4Nc5ccccc5C=C4CN3C2=O KLWPJMFMVPTNCC-UHFFFAOYSA-N 0.000 claims 1
- 201000009030 Carcinoma Diseases 0.000 claims 1
- 206010071602 Genetic polymorphism Diseases 0.000 claims 1
- 208000017604 Hodgkin disease Diseases 0.000 claims 1
- 208000010747 Hodgkins lymphoma Diseases 0.000 claims 1
- 208000028018 Lymphocytic leukaemia Diseases 0.000 claims 1
- 208000035490 Megakaryoblastic Acute Leukemia Diseases 0.000 claims 1
- 208000035489 Monocytic Acute Leukemia Diseases 0.000 claims 1
- 208000033776 Myeloid Acute Leukemia Diseases 0.000 claims 1
- 206010052399 Neuroendocrine tumour Diseases 0.000 claims 1
- 208000033826 Promyelocytic Acute Leukemia Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 206010039491 Sarcoma Diseases 0.000 claims 1
- 208000013593 acute megakaryoblastic leukemia Diseases 0.000 claims 1
- 208000020700 acute megakaryocytic leukemia Diseases 0.000 claims 1
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical compound C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 claims 1
- 229940127093 camptothecin Drugs 0.000 claims 1
- 208000002458 carcinoid tumor Diseases 0.000 claims 1
- VSJKWCGYPAHWDS-UHFFFAOYSA-N dl-camptothecin Natural products C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)C5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-UHFFFAOYSA-N 0.000 claims 1
- 208000003747 lymphoid leukemia Diseases 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 208000016065 neuroendocrine neoplasm Diseases 0.000 claims 1
- 201000011519 neuroendocrine tumor Diseases 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- DVEQYIKAWOEGBD-OPTOVBNMSA-N CCCO/N=C/c1c(CN(C2=CC([C@]3(C(C)C)O)=C4COC3=O)C4=O)c2nc2c1cccc2 Chemical compound CCCO/N=C/c1c(CN(C2=CC([C@]3(C(C)C)O)=C4COC3=O)C4=O)c2nc2c1cccc2 DVEQYIKAWOEGBD-OPTOVBNMSA-N 0.000 description 3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05027997.5 | 2005-12-21 | ||
| EP05027997 | 2005-12-21 | ||
| PCT/EP2006/069666 WO2007071603A1 (en) | 2005-12-21 | 2006-12-13 | Treatment of drug-resistant tumors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009520754A JP2009520754A (ja) | 2009-05-28 |
| JP2009520754A5 true JP2009520754A5 (enExample) | 2010-01-28 |
| JP5657205B2 JP5657205B2 (ja) | 2015-01-21 |
Family
ID=35911064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008546388A Expired - Fee Related JP5657205B2 (ja) | 2005-12-21 | 2006-12-13 | 薬物耐性腫瘍の治療 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7888368B2 (enExample) |
| EP (1) | EP1962850B1 (enExample) |
| JP (1) | JP5657205B2 (enExample) |
| KR (1) | KR101366868B1 (enExample) |
| CN (1) | CN101340910B (enExample) |
| AT (1) | ATE548038T1 (enExample) |
| AU (1) | AU2006328607B2 (enExample) |
| BR (1) | BRPI0620209A2 (enExample) |
| CA (1) | CA2631868C (enExample) |
| CY (1) | CY1112814T1 (enExample) |
| DK (1) | DK1962850T3 (enExample) |
| EA (1) | EA016487B1 (enExample) |
| ES (1) | ES2382819T3 (enExample) |
| HR (1) | HRP20120359T1 (enExample) |
| PL (1) | PL1962850T3 (enExample) |
| PT (1) | PT1962850E (enExample) |
| RS (1) | RS52272B (enExample) |
| SI (1) | SI1962850T1 (enExample) |
| WO (1) | WO2007071603A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008098701A1 (en) * | 2007-02-13 | 2008-08-21 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Broad-spectrum anti-cancer treatment based on iminocamptothecin derivatives |
| JP5765937B2 (ja) * | 2007-08-01 | 2015-08-19 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニＳｉｇｍａ−Ｔａｕ Ｉｎｄｕｓｔｒｉｅ Ｆａｒｍａｃｅｕｔｉｃｈｅ Ｒｉｕｎｉｔｅ Ｓｏｃｉｅｔａ Ｐｅｒ Ａｚｉｏｎｉ | 小児腫瘍の治療 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1282673B1 (it) * | 1996-02-23 | 1998-03-31 | Ist Naz Stud Cura Dei Tumori | Derivati della camptotecina e loro uso come agenti antitumorali |
| PT1044977E (pt) * | 1999-03-09 | 2002-09-30 | Sigma Tau Ind Farmaceuti | Derivados de camptotecina com actividade antitumoral |
-
2006
- 2006-12-13 BR BRPI0620209-8A patent/BRPI0620209A2/pt not_active IP Right Cessation
- 2006-12-13 SI SI200631316T patent/SI1962850T1/sl unknown
- 2006-12-13 PT PT06830600T patent/PT1962850E/pt unknown
- 2006-12-13 EP EP06830600A patent/EP1962850B1/en active Active
- 2006-12-13 WO PCT/EP2006/069666 patent/WO2007071603A1/en not_active Ceased
- 2006-12-13 CN CN2006800482417A patent/CN101340910B/zh not_active Expired - Fee Related
- 2006-12-13 RS RS20120175A patent/RS52272B/sr unknown
- 2006-12-13 DK DK06830600.0T patent/DK1962850T3/da active
- 2006-12-13 CA CA2631868A patent/CA2631868C/en not_active Expired - Fee Related
- 2006-12-13 JP JP2008546388A patent/JP5657205B2/ja not_active Expired - Fee Related
- 2006-12-13 US US12/096,884 patent/US7888368B2/en not_active Expired - Fee Related
- 2006-12-13 ES ES06830600T patent/ES2382819T3/es active Active
- 2006-12-13 AU AU2006328607A patent/AU2006328607B2/en not_active Ceased
- 2006-12-13 EA EA200870073A patent/EA016487B1/ru not_active IP Right Cessation
- 2006-12-13 KR KR1020087016809A patent/KR101366868B1/ko not_active Expired - Fee Related
- 2006-12-13 HR HRP20120359TT patent/HRP20120359T1/hr unknown
- 2006-12-13 AT AT06830600T patent/ATE548038T1/de active
- 2006-12-13 PL PL06830600T patent/PL1962850T3/pl unknown
-
2012
- 2012-06-01 CY CY20121100497T patent/CY1112814T1/el unknown
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