ES2382819T3 - Tratamiento de tumores resistentes a fármacos - Google Patents

Tratamiento de tumores resistentes a fármacos Download PDF

Info

Publication number
ES2382819T3
ES2382819T3 ES06830600T ES06830600T ES2382819T3 ES 2382819 T3 ES2382819 T3 ES 2382819T3 ES 06830600 T ES06830600 T ES 06830600T ES 06830600 T ES06830600 T ES 06830600T ES 2382819 T3 ES2382819 T3 ES 2382819T3
Authority
ES
Spain
Prior art keywords
tumor
topoisomerase
treatment
drug
leukemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES06830600T
Other languages
English (en)
Spanish (es)
Inventor
Claudio Pisano
Loredana Vesci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Application granted granted Critical
Publication of ES2382819T3 publication Critical patent/ES2382819T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
ES06830600T 2005-12-21 2006-12-13 Tratamiento de tumores resistentes a fármacos Active ES2382819T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05027997 2005-12-21
EP05027997 2005-12-21
PCT/EP2006/069666 WO2007071603A1 (en) 2005-12-21 2006-12-13 Treatment of drug-resistant tumors

Publications (1)

Publication Number Publication Date
ES2382819T3 true ES2382819T3 (es) 2012-06-13

Family

ID=35911064

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06830600T Active ES2382819T3 (es) 2005-12-21 2006-12-13 Tratamiento de tumores resistentes a fármacos

Country Status (19)

Country Link
US (1) US7888368B2 (enExample)
EP (1) EP1962850B1 (enExample)
JP (1) JP5657205B2 (enExample)
KR (1) KR101366868B1 (enExample)
CN (1) CN101340910B (enExample)
AT (1) ATE548038T1 (enExample)
AU (1) AU2006328607B2 (enExample)
BR (1) BRPI0620209A2 (enExample)
CA (1) CA2631868C (enExample)
CY (1) CY1112814T1 (enExample)
DK (1) DK1962850T3 (enExample)
EA (1) EA016487B1 (enExample)
ES (1) ES2382819T3 (enExample)
HR (1) HRP20120359T1 (enExample)
PL (1) PL1962850T3 (enExample)
PT (1) PT1962850E (enExample)
RS (1) RS52272B (enExample)
SI (1) SI1962850T1 (enExample)
WO (1) WO2007071603A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008098701A1 (en) * 2007-02-13 2008-08-21 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Broad-spectrum anti-cancer treatment based on iminocamptothecin derivatives
JP5765937B2 (ja) * 2007-08-01 2015-08-19 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニSigma−Tau Industrie Farmaceutiche Riunite Societa Per Azioni 小児腫瘍の治療

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1282673B1 (it) * 1996-02-23 1998-03-31 Ist Naz Stud Cura Dei Tumori Derivati della camptotecina e loro uso come agenti antitumorali
PT1044977E (pt) * 1999-03-09 2002-09-30 Sigma Tau Ind Farmaceuti Derivados de camptotecina com actividade antitumoral

Also Published As

Publication number Publication date
CN101340910A (zh) 2009-01-07
EP1962850A1 (en) 2008-09-03
HRP20120359T1 (hr) 2012-06-30
JP2009520754A (ja) 2009-05-28
CN101340910B (zh) 2012-12-12
WO2007071603A1 (en) 2007-06-28
DK1962850T3 (da) 2012-06-18
EA016487B1 (ru) 2012-05-30
US7888368B2 (en) 2011-02-15
PL1962850T3 (pl) 2012-07-31
AU2006328607A1 (en) 2007-06-28
CA2631868C (en) 2014-02-11
HK1124776A1 (zh) 2009-07-24
CA2631868A1 (en) 2007-06-28
BRPI0620209A2 (pt) 2011-11-01
PT1962850E (pt) 2012-05-21
ATE548038T1 (de) 2012-03-15
AU2006328607B2 (en) 2012-04-19
JP5657205B2 (ja) 2015-01-21
EP1962850B1 (en) 2012-03-07
CY1112814T1 (el) 2016-02-10
EA200870073A1 (ru) 2009-12-30
RS52272B (sr) 2012-10-31
KR101366868B1 (ko) 2014-02-21
KR20080078055A (ko) 2008-08-26
SI1962850T1 (sl) 2012-06-29
US20080312265A1 (en) 2008-12-18

Similar Documents

Publication Publication Date Title
US8658668B2 (en) PI3 kinase/mTOR dual inhibitor
MX2007000457A (es) Inhibidores de indoleamina 2,3-dioxigenasa (ido).
JP2018536635A (ja) プロテアソーム阻害剤およびその用途
ES2958528T3 (es) Macrociclos sustituidos útiles como inhibidores de quinasas
ES2930081T3 (es) Pirazolopirimidinas sustituidas útiles como inhibidores de quinasas
CN118354794A (zh) Kras g12d抑制剂与伊立替康的组合及相关治疗方法
EP2271332B1 (en) Use of compounds in the treatment of tauopathy
ES2382819T3 (es) Tratamiento de tumores resistentes a fármacos
De Cesare et al. Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series
KR20100051837A (ko) 소아 종양의 치료
RU2352572C2 (ru) Пентагидрат моногидрохлорида топотекана в кристаллической форме, соответствующие композиции на их основе, способы получения и/или способы лечения
TWI472330B (zh) 用於癌症治療之增敏劑、套組及用途
US8853233B2 (en) Broad-spectrum anti-cancer treatment based on iminocamptothecin derivatives
ES2662917T3 (es) Compuestos de quinona y sus usos para el tratamiento del cáncer
US8188130B1 (en) Anti-cancer hydantoin compounds and methods
Cao et al. Anticancer activity of new haloalkyl camptothecin esters against human cancer cell lines and human tumor xenografts grown in nude mice
AU2004255949B2 (en) 7-polyaminoalkyl(oxy)iminomethylcamptothecins bearing protective groups
CN118512450A (zh) 粉防己碱在制备细胞巨胞饮作用抑制剂中的应用
MXPA06000471A (en) 7-polyaminoalkyl(oxy)iminomethylcamptothecins bearing protective groups
ITMI932690A1 (it) Acilsulfammidi ad attivita' antitumorale