JP2009520694A - 界面活性燐酸カルシウム - Google Patents
界面活性燐酸カルシウム Download PDFInfo
- Publication number
- JP2009520694A JP2009520694A JP2008544714A JP2008544714A JP2009520694A JP 2009520694 A JP2009520694 A JP 2009520694A JP 2008544714 A JP2008544714 A JP 2008544714A JP 2008544714 A JP2008544714 A JP 2008544714A JP 2009520694 A JP2009520694 A JP 2009520694A
- Authority
- JP
- Japan
- Prior art keywords
- group
- nitrogen atom
- phosphate
- complex according
- nitrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
- A61K6/69—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/70—Preparations for dentistry comprising inorganic additives
- A61K6/78—Pigments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
- A61K6/838—Phosphorus compounds, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
- A61K6/864—Phosphate cements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B25/00—Phosphorus; Compounds thereof
- C01B25/16—Oxyacids of phosphorus; Salts thereof
- C01B25/26—Phosphates
- C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/36—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Plastic & Reconstructive Surgery (AREA)
- Birds (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75133505P | 2005-12-16 | 2005-12-16 | |
| PCT/AU2006/001914 WO2007068062A1 (en) | 2005-12-16 | 2006-12-15 | Surface active calcium phosphates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009520694A true JP2009520694A (ja) | 2009-05-28 |
| JP2009520694A5 JP2009520694A5 (enExample) | 2010-01-28 |
Family
ID=38162495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008544714A Pending JP2009520694A (ja) | 2005-12-16 | 2006-12-15 | 界面活性燐酸カルシウム |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20080286216A1 (enExample) |
| EP (1) | EP1960057A4 (enExample) |
| JP (1) | JP2009520694A (enExample) |
| CN (2) | CN102358746A (enExample) |
| AU (1) | AU2006324304A1 (enExample) |
| BR (1) | BRPI0620691A2 (enExample) |
| CA (1) | CA2632009A1 (enExample) |
| WO (1) | WO2007068062A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013510799A (ja) * | 2009-11-11 | 2013-03-28 | オーラル ヘルス オーストラリア ピーティーワイ リミテッド | 抗バイオフィルム糖ペプチド |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10130561B2 (en) | 2006-01-31 | 2018-11-20 | Robert L. Karlinsey | Functionalized calcium phosphate hybrid systems for confectionery and foodstuff applications |
| US9205036B2 (en) | 2007-01-31 | 2015-12-08 | Robert Karlinsey | Dental composition |
| US20160317580A9 (en) * | 2007-01-31 | 2016-11-03 | Robert L. Karlinsey | Composition and method for dental remineralization |
| US9023373B2 (en) | 2007-01-31 | 2015-05-05 | Indiana Nanotech | Functionalized calcium phosphate hybrid systems for the remineralization of teeth and a method for producing the same |
| MY155564A (en) * | 2008-02-08 | 2015-10-30 | Colgate Palmolive Co | Arginine salts and their uses for the treatment of illnesses in the oral cavity |
| MX2010005006A (es) * | 2008-02-08 | 2010-05-27 | Colgate Palmolive Co | Producto para el cuidado oral y metodos de uso y fabricacion del mismo. |
| DE102011056018A1 (de) * | 2011-12-05 | 2013-06-06 | Gelita Ag | Zuckersüßware auf Basis eines Gelatinegels und Verfahren zur Herstellung |
| CN104523470A (zh) * | 2014-12-04 | 2015-04-22 | 成都锦汇科技有限公司 | 一种中药健齿牙膏 |
| WO2017044469A1 (en) * | 2015-09-10 | 2017-03-16 | The University Of Florida Research Foundation, Inc. | Arginine-containing restorative dental materials and methods of preventing and controlling caries associated with dental work |
| CN110255502B (zh) * | 2019-06-14 | 2020-11-06 | 贵州新东浩化工材料科技有限公司 | 白肥制氟化氢联产富钙及普钙工艺 |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3943241A (en) * | 1971-08-30 | 1976-03-09 | General Mills, Inc. | Cariostatic composition |
| JPS59106420A (ja) * | 1982-11-19 | 1984-06-20 | ケマ−・アソシエイツ,インコ−ポレ−テツド | 自己消毒性カ−ペットおよびその形成法 |
| JPH035417A (ja) * | 1989-05-18 | 1991-01-11 | L'oreal Sa | ポリカチオン性ポリマーのフッ化物を含有する抗齲蝕作用をもつ新規歯みがき組成物 |
| JPH05139944A (ja) * | 1991-11-19 | 1993-06-08 | Sunstar Inc | う蝕・歯周病予防用口腔用組成物 |
| JPH11246374A (ja) * | 1998-02-25 | 1999-09-14 | Lion Corp | 口腔用組成物 |
| WO2000078270A1 (en) * | 1999-06-23 | 2000-12-28 | The Research Foundation Of State University Of New York | Dental anti-hypersensitivity composition and method |
| JP2001504083A (ja) * | 1996-03-05 | 2001-03-27 | ザ リサーチ ファウンデーション オブ ザ ステイト ユニバーシティ オブ ニューヨーク | 抗齲蝕口用組成物 |
| JP2001172168A (ja) * | 1999-12-20 | 2001-06-26 | Kao Corp | 皮膚洗浄方法 |
| JP2002500626A (ja) * | 1997-03-13 | 2002-01-08 | ザ ユニヴァーシティ オブ メルボルン | カルシウムホスホペプチド複合体 |
| JP2005145952A (ja) * | 2003-10-23 | 2005-06-09 | Gc Corp | う蝕予防用組成物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4215064A (en) * | 1978-11-30 | 1980-07-29 | Johnson & Johnson | Phosphobetaines |
| US4261911A (en) * | 1978-11-30 | 1981-04-14 | Johnson & Johnson | Phosphitaines |
| US4380637A (en) * | 1978-11-30 | 1983-04-19 | Johnson & Johnson/Mona Industries, Inc. | Imidazoline phosphobetaines |
| US5130123A (en) * | 1981-03-04 | 1992-07-14 | The University Of Melbourne | Dentifrice |
| US4382046A (en) * | 1981-09-22 | 1983-05-03 | Ceramic Cooling Tower Company | Water cooling tower with layers of multi-cell tiles and spacers |
| US5015628A (en) * | 1986-06-12 | 1991-05-14 | The University Of Melbourne | Anticariogenic phosphopeptides |
| SU1595847A1 (ru) * | 1988-08-08 | 1990-09-30 | Казанский научно-исследовательский технологический и проектный институт химико-фотографической промышленности Производственного объединения "Тасма" | Три-[пиридиний(пиколиний)хлоридо]фосфаты в качестве дубителей желатинсодержащих слоев галогенсеребр ных фотографических материалов |
| US5460803A (en) * | 1989-05-24 | 1995-10-24 | American Dental Association Health Foundation | Methods and compositions for mineralizing and fluoridating calcified tissues |
| FR2648133B1 (fr) * | 1989-06-08 | 1992-02-21 | Sanofi Sa | Lauramides n-substitues, leur preparation et compositions les contenant |
| JPH04217612A (ja) * | 1990-12-18 | 1992-08-07 | Kao Corp | ゲル状毛髪化粧料 |
| US5227154A (en) * | 1991-08-22 | 1993-07-13 | The University Of Melbourne | Phosphopeptides for the treatment of dental calculus |
| US5958380A (en) * | 1997-07-07 | 1999-09-28 | Enamelon, Inc. | Chewing gum products and the use thereof for remineralizing subsurface dental lesions and for mineralizing exposed dentinal tubules |
| JP3719874B2 (ja) * | 1998-04-24 | 2005-11-24 | サンスター株式会社 | 口腔用組成物 |
| US6180806B1 (en) * | 1999-09-23 | 2001-01-30 | Phoenix Research Corp. | Glyceryl phosphobetaine compounds |
| AUPR517701A0 (en) * | 2001-05-21 | 2001-06-14 | University Of Melbourne, The | Dental restorative materials |
| US20050089481A1 (en) * | 2003-10-23 | 2005-04-28 | Gc Corporation | Composition for caries prevention |
-
2006
- 2006-12-15 CN CN2011101626856A patent/CN102358746A/zh active Pending
- 2006-12-15 EP EP06828022A patent/EP1960057A4/en not_active Withdrawn
- 2006-12-15 AU AU2006324304A patent/AU2006324304A1/en not_active Abandoned
- 2006-12-15 WO PCT/AU2006/001914 patent/WO2007068062A1/en not_active Ceased
- 2006-12-15 CN CNA2006800470142A patent/CN101330943A/zh active Pending
- 2006-12-15 JP JP2008544714A patent/JP2009520694A/ja active Pending
- 2006-12-15 BR BRPI0620691-3A patent/BRPI0620691A2/pt not_active IP Right Cessation
- 2006-12-15 CA CA002632009A patent/CA2632009A1/en not_active Abandoned
- 2006-12-15 US US12/095,044 patent/US20080286216A1/en not_active Abandoned
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3943241A (en) * | 1971-08-30 | 1976-03-09 | General Mills, Inc. | Cariostatic composition |
| JPS59106420A (ja) * | 1982-11-19 | 1984-06-20 | ケマ−・アソシエイツ,インコ−ポレ−テツド | 自己消毒性カ−ペットおよびその形成法 |
| JPH035417A (ja) * | 1989-05-18 | 1991-01-11 | L'oreal Sa | ポリカチオン性ポリマーのフッ化物を含有する抗齲蝕作用をもつ新規歯みがき組成物 |
| JPH05139944A (ja) * | 1991-11-19 | 1993-06-08 | Sunstar Inc | う蝕・歯周病予防用口腔用組成物 |
| JP2001504083A (ja) * | 1996-03-05 | 2001-03-27 | ザ リサーチ ファウンデーション オブ ザ ステイト ユニバーシティ オブ ニューヨーク | 抗齲蝕口用組成物 |
| JP2002500626A (ja) * | 1997-03-13 | 2002-01-08 | ザ ユニヴァーシティ オブ メルボルン | カルシウムホスホペプチド複合体 |
| JPH11246374A (ja) * | 1998-02-25 | 1999-09-14 | Lion Corp | 口腔用組成物 |
| WO2000078270A1 (en) * | 1999-06-23 | 2000-12-28 | The Research Foundation Of State University Of New York | Dental anti-hypersensitivity composition and method |
| JP2001172168A (ja) * | 1999-12-20 | 2001-06-26 | Kao Corp | 皮膚洗浄方法 |
| JP2005145952A (ja) * | 2003-10-23 | 2005-06-09 | Gc Corp | う蝕予防用組成物 |
Non-Patent Citations (1)
| Title |
|---|
| JPN6012042523; Benedini, Francesca; Ferrario, Francesco; Sala, Alberto: 'Carbon-13 NMR study of 1-substituted imidazoles' Magnetic Resonance in Chemistry 30(11), 1992, 1137-40 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013510799A (ja) * | 2009-11-11 | 2013-03-28 | オーラル ヘルス オーストラリア ピーティーワイ リミテッド | 抗バイオフィルム糖ペプチド |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1960057A1 (en) | 2008-08-27 |
| EP1960057A4 (en) | 2013-03-27 |
| AU2006324304A1 (en) | 2007-06-21 |
| US20080286216A1 (en) | 2008-11-20 |
| BRPI0620691A2 (pt) | 2011-11-22 |
| CN102358746A (zh) | 2012-02-22 |
| CN101330943A (zh) | 2008-12-24 |
| CA2632009A1 (en) | 2007-06-21 |
| WO2007068062A1 (en) | 2007-06-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4541455B2 (ja) | カルシウムホスホペプチド複合体 | |
| US9241883B2 (en) | Ionic complexes | |
| CN103826605B (zh) | 口腔用组合物 | |
| Gupta et al. | CPP-ACP complex as a new adjunctive agent for remineralisation: a review. | |
| EP3538057B1 (en) | Oral care compositions | |
| CN101098675B (zh) | 稳定的磷酸钙复合物 | |
| RU2406522C2 (ru) | Способ уменьшения воспаления ткани ротовой полости с использованием экстракта магнолии | |
| JP2006518744A (ja) | 抗感受性、抗カリエス、抗しみ、抗歯垢、ウルトラマイルド口腔衛生物質 | |
| JP2003513899A (ja) | 改良された第1錫系口腔組成物 | |
| RU2738847C1 (ru) | Композиции для ухода за полостью рта и способы их применения | |
| RU2718904C1 (ru) | Композиции для ухода за полостью рта и способы их применения | |
| EP3378466A1 (en) | Composition for use in oral cavity | |
| JP2009520694A (ja) | 界面活性燐酸カルシウム | |
| JP7053542B2 (ja) | スフィンゴシン系化合物による材料の保護 | |
| CA3226497A1 (en) | Oral care compositions with phosphopeptides for use against dental hypersensitivity and/or xerostomia | |
| JP7789515B2 (ja) | 糖化抑制剤 | |
| AU746314B2 (en) | Calcium phosphopeptide complexes | |
| JPH09502998A (ja) | 実質的抗菌性ホスフェート | |
| CN101119739A (zh) | 含有游离-b-环类黄酮抗氧化剂的口腔护理组合物的使用方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20091202 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20091202 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20120731 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20120814 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20130205 |