JP2009520480A5 - - Google Patents
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- Publication number
- JP2009520480A5 JP2009520480A5 JP2008546287A JP2008546287A JP2009520480A5 JP 2009520480 A5 JP2009520480 A5 JP 2009520480A5 JP 2008546287 A JP2008546287 A JP 2008546287A JP 2008546287 A JP2008546287 A JP 2008546287A JP 2009520480 A5 JP2009520480 A5 JP 2009520480A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- dimer
- polypeptide dimer
- monomer
- fragments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05028420A EP1801121A1 (en) | 2005-12-23 | 2005-12-23 | Soluble gp130 molecule variants useful as a medicament |
| EP05028420.7 | 2005-12-23 | ||
| PCT/EP2006/012515 WO2007071449A1 (en) | 2005-12-23 | 2006-12-22 | Soluble gp130 molecule variants useful as a medicament |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009520480A JP2009520480A (ja) | 2009-05-28 |
| JP2009520480A5 true JP2009520480A5 (https=) | 2010-01-21 |
| JP5390191B2 JP5390191B2 (ja) | 2014-01-15 |
Family
ID=36233865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008546287A Active JP5390191B2 (ja) | 2005-12-23 | 2006-12-22 | 医薬として有用な可溶性ｇｐ１３０分子変異体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7851182B2 (https=) |
| EP (2) | EP1801121A1 (https=) |
| JP (1) | JP5390191B2 (https=) |
| AT (1) | ATE471945T1 (https=) |
| AU (1) | AU2006328909A1 (https=) |
| CA (1) | CA2633213A1 (https=) |
| DE (1) | DE602006015103D1 (https=) |
| ES (1) | ES2347694T3 (https=) |
| WO (1) | WO2007071449A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1873166T3 (da) | 2006-06-30 | 2010-12-20 | Conaris Res Inst Ag | Forbedrede sgp 130Fc-dimerer |
| EP2174667B1 (en) * | 2007-07-26 | 2017-01-04 | Osaka University | Agent for treatment of ophthalmia containing interleukin-6 receptor inhibitor as active ingredient |
| EP2050759A1 (en) * | 2007-10-19 | 2009-04-22 | CONARIS research institute AG | Soluble gp 130 muteins with improved binding activity |
| RS65665B1 (sr) | 2014-12-01 | 2024-07-31 | Ferring Bv | Selektivne kompozicije inhibitora il-6-trans-signalizacije |
| LT3226888T (lt) | 2014-12-01 | 2021-05-25 | Ferring B.V. | Selektyvaus il-6-trans-signalinio inhibitoriaus skyrimas |
| US20190002915A1 (en) * | 2015-12-14 | 2019-01-03 | The Trustees Of The University Of Pennsylvania | Compositions and methods for regulatable antibody expression |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994012520A1 (en) * | 1992-11-20 | 1994-06-09 | Enzon, Inc. | Linker for linked fusion polypeptides |
| CA2344277A1 (en) * | 1998-09-22 | 2000-03-30 | University Of Maryland, Baltimore | Cystine knot growth factor mutants |
| CZ20012406A3 (cs) * | 1999-01-07 | 2002-03-13 | Lexigen Pharmaceuticals, Corp. | Exprese a export proteinů působících proti obezitě jako Fc fúzních proteinů |
| EP1148065B1 (en) * | 2000-04-21 | 2008-01-02 | CONARIS research institute AG | Fusion proteins comprising two soluble gp130 molecules |
| ES2302845T3 (es) * | 2001-10-19 | 2008-08-01 | Zymogenetics, Inc. | Factor de crecimiento dimerizado y materiales y metodos para producirlo. |
| EP1491554A1 (en) * | 2003-06-23 | 2004-12-29 | CONARIS research institute AG | PEGylated soluble gp130-dimers useful as a medicament |
| JP2008504012A (ja) * | 2004-01-28 | 2008-02-14 | シントニックス・ファーマシューティカルズ・インコーポレーテッド | 不妊治療のためのへテロ二量体卵胞刺激ホルモン−Ｆｃ（ＦＳＨ−Ｆｃ）融合タンパク質 |
-
2005
- 2005-12-23 EP EP05028420A patent/EP1801121A1/en not_active Withdrawn
-
2006
- 2006-12-22 EP EP06841152A patent/EP1994053B1/en active Active
- 2006-12-22 WO PCT/EP2006/012515 patent/WO2007071449A1/en not_active Ceased
- 2006-12-22 AU AU2006328909A patent/AU2006328909A1/en not_active Abandoned
- 2006-12-22 AT AT06841152T patent/ATE471945T1/de not_active IP Right Cessation
- 2006-12-22 DE DE602006015103T patent/DE602006015103D1/de active Active
- 2006-12-22 ES ES06841152T patent/ES2347694T3/es active Active
- 2006-12-22 JP JP2008546287A patent/JP5390191B2/ja active Active
- 2006-12-22 US US12/158,285 patent/US7851182B2/en active Active
- 2006-12-22 CA CA002633213A patent/CA2633213A1/en not_active Abandoned
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