JP2005523681A5 - - Google Patents

Info

Publication number

JP2005523681A5

JP2005523681A5 JP2003532654A JP2003532654A JP2005523681A5 JP 2005523681 A5 JP2005523681 A5 JP 2005523681A5 JP 2003532654 A JP2003532654 A JP 2003532654A JP 2003532654 A JP2003532654 A JP 2003532654A JP 2005523681 A5 JP2005523681 A5 JP 2005523681A5

Authority

JP

Japan

Prior art keywords

ulbp4

protein

seq

polypeptide

isolated

Prior art date

2002-10-04

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 101001132524 Homo sapiens Retinoic acid early transcript 1E Proteins 0.000 claims 42
• 102100033964 Retinoic acid early transcript 1E Human genes 0.000 claims 42
• 108090000765 processed proteins & peptides Proteins 0.000 claims 22
• 229920001184 polypeptide Polymers 0.000 claims 17
• 102000004196 processed proteins & peptides Human genes 0.000 claims 17
• 102000040430 polynucleotide Human genes 0.000 claims 14
• 108091033319 polynucleotide Proteins 0.000 claims 14
• 239000002157 polynucleotide Substances 0.000 claims 14
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 12
• 210000004027 cell Anatomy 0.000 claims 12
• 238000000034 method Methods 0.000 claims 10
• 101001109501 Homo sapiens NKG2-D type II integral membrane protein Proteins 0.000 claims 8
• 102100022680 NKG2-D type II integral membrane protein Human genes 0.000 claims 8
• 125000003275 alpha amino acid group Chemical group 0.000 claims 8
• 150000001413 amino acids Chemical class 0.000 claims 8
• 239000002773 nucleotide Substances 0.000 claims 6
• 125000003729 nucleotide group Chemical group 0.000 claims 6
• 102000004169 proteins and genes Human genes 0.000 claims 4
• 108090000623 proteins and genes Proteins 0.000 claims 4
• 238000004519 manufacturing process Methods 0.000 claims 3
• 102000039446 nucleic acids Human genes 0.000 claims 3
• 108020004707 nucleic acids Proteins 0.000 claims 3
• 150000007523 nucleic acids Chemical class 0.000 claims 3
• 239000003814 drug Substances 0.000 claims 2
• 230000028993 immune response Effects 0.000 claims 2
• 208000015181 infectious disease Diseases 0.000 claims 2
• 239000008194 pharmaceutical composition Substances 0.000 claims 2
• 208000023275 Autoimmune disease Diseases 0.000 claims 1
• 102000019034 Chemokines Human genes 0.000 claims 1
• 108010012236 Chemokines Proteins 0.000 claims 1
• 102000004127 Cytokines Human genes 0.000 claims 1
• 108090000695 Cytokines Proteins 0.000 claims 1
• 210000001744 T-lymphocyte Anatomy 0.000 claims 1
• 208000036142 Viral infection Diseases 0.000 claims 1
• 230000003213 activating effect Effects 0.000 claims 1
• 239000003795 chemical substances by application Substances 0.000 claims 1
• 238000012258 culturing Methods 0.000 claims 1
• 231100000433 cytotoxic Toxicity 0.000 claims 1
• 230000001472 cytotoxic effect Effects 0.000 claims 1
• 230000003013 cytotoxicity Effects 0.000 claims 1
• 231100000135 cytotoxicity Toxicity 0.000 claims 1
• 230000002222 downregulating effect Effects 0.000 claims 1
• 208000027866 inflammatory disease Diseases 0.000 claims 1
• 210000004962 mammalian cell Anatomy 0.000 claims 1
• 210000000822 natural killer cell Anatomy 0.000 claims 1
• 238000006384 oligomerization reaction Methods 0.000 claims 1
• 230000002285 radioactive effect Effects 0.000 claims 1
• 230000009385 viral infection Effects 0.000 claims 1