JP2009519895A5 - - Google Patents

Download PDF

Info

Publication number
JP2009519895A5
JP2009519895A5 JP2008536730A JP2008536730A JP2009519895A5 JP 2009519895 A5 JP2009519895 A5 JP 2009519895A5 JP 2008536730 A JP2008536730 A JP 2008536730A JP 2008536730 A JP2008536730 A JP 2008536730A JP 2009519895 A5 JP2009519895 A5 JP 2009519895A5
Authority
JP
Japan
Prior art keywords
xaa
derived diffusible
antibody
diffusible ligand
ligand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008536730A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009519895A (ja
JP5289963B2 (ja
JP2009519895A6 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/040508 external-priority patent/WO2007050359A2/en
Publication of JP2009519895A publication Critical patent/JP2009519895A/ja
Publication of JP2009519895A6 publication Critical patent/JP2009519895A6/ja
Publication of JP2009519895A5 publication Critical patent/JP2009519895A5/ja
Application granted granted Critical
Publication of JP5289963B2 publication Critical patent/JP5289963B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2008536730A 2005-10-21 2006-10-17 抗addlモノクローナル抗体およびその使用 Active JP5289963B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2005381125 2005-10-21
USPCT/US2005/38125 2005-10-21
PCT/US2006/040508 WO2007050359A2 (en) 2005-10-21 2006-10-17 Anti-addl monoclonal antibody and use thereof

Publications (4)

Publication Number Publication Date
JP2009519895A JP2009519895A (ja) 2009-05-21
JP2009519895A6 JP2009519895A6 (ja) 2009-12-24
JP2009519895A5 true JP2009519895A5 (enExample) 2012-04-05
JP5289963B2 JP5289963B2 (ja) 2013-09-11

Family

ID=39671607

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008536730A Active JP5289963B2 (ja) 2005-10-21 2006-10-17 抗addlモノクローナル抗体およびその使用

Country Status (8)

Country Link
EP (1) EP1940466B1 (enExample)
JP (1) JP5289963B2 (enExample)
CN (1) CN101291692A (enExample)
AU (1) AU2006306553B9 (enExample)
CA (1) CA2626783A1 (enExample)
NO (1) NO20082288L (enExample)
RU (1) RU2008120027A (enExample)
WO (1) WO2007050359A2 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002003911A2 (en) 2000-07-07 2002-01-17 Lars Lannfelt Prevention and treatment of alzheimer's disease
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
SE0401601D0 (sv) 2004-06-21 2004-06-21 Bioarctic Neuroscience Ab Protofibril specific antibodies and uses thereof
PT1976877E (pt) 2005-11-30 2014-04-29 Abbvie Inc Anticorpos monoclonais contra proteína beta-amilóide e suas utilizações
CN117903302A (zh) 2005-11-30 2024-04-19 Abbvie 公司 抗-Aβ球聚体抗体,其相关产品,生产所述抗体的方法,所述抗体的应用以及使用方法
RU2429244C2 (ru) 2006-03-23 2011-09-20 Байоарктик Ньюросайенс Аб Улучшенные селективные в отношении протофибрилл антитела и их применение
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
US20100311767A1 (en) 2007-02-27 2010-12-09 Abbott Gmbh & Co. Kg Method for the treatment of amyloidoses
US7931899B2 (en) 2007-05-14 2011-04-26 Medtronic, Inc Humanized anti-amyloid beta antibodies
US8323654B2 (en) 2007-05-14 2012-12-04 Medtronic, Inc. Anti-amyloid beta antibodies conjugated to sialic acid-containing molecules
US8048420B2 (en) 2007-06-12 2011-11-01 Ac Immune S.A. Monoclonal antibody
US8613923B2 (en) 2007-06-12 2013-12-24 Ac Immune S.A. Monoclonal antibody
PL2170389T3 (pl) * 2007-06-12 2015-03-31 Ac Immune Sa Humanizowane przeciwciało przeciw amyloidowi beta
ES2445590T3 (es) 2007-10-05 2014-03-04 Genentech, Inc. Uso de anticuerpo anti-amiloide beta en enfermedades oculares
WO2009070648A2 (en) * 2007-11-27 2009-06-04 Medtronic, Inc. Humanized anti-amyloid beta antibodies
US9217024B2 (en) 2007-12-18 2015-12-22 Acumen Pharmaceuticals, Inc. ADDL receptor polypeptides, polynucleotides and host cells for recombinant production
EP2321338A1 (en) * 2008-08-14 2011-05-18 Merck Sharp & Dohme Corp. Methods for purifying antibodies using protein a affinity chromatography
DK2510359T3 (en) 2009-12-11 2015-12-07 Araclón Biotech S L METHODS AND REAGENTS FOR IMPROVED DETECTION OF AMYLOID-BETA PEPTIDES
CN104744591B (zh) 2010-04-15 2022-09-27 Abbvie德国有限责任两合公司 β淀粉样蛋白结合蛋白
US9320793B2 (en) 2010-07-14 2016-04-26 Acumen Pharmaceuticals, Inc. Method for treating a disease associated with soluble, oligomeric species of amyloid beta 1-42
ES2573135T3 (es) 2010-07-14 2016-06-06 Merck Sharp & Dohme Corp. Anticuerpo monoclonal anti-ADDL y usos del mismo
US9176151B2 (en) 2010-07-14 2015-11-03 Acumen Pharmaceuticals, Inc. Antibodies, kit and method for detecting amyloid beta oligomers
US9221900B2 (en) 2010-07-30 2015-12-29 Ac Immune S.A. Methods for identifying safe and functional humanized antibodies
EP3533803B1 (en) 2010-08-14 2021-10-27 AbbVie Inc. Anti-amyloid-beta antibodies
EP2511296A1 (en) 2011-04-12 2012-10-17 Araclón Biotech, S. L. Antibody, kit and method for determination of amyloid peptides
US20140302532A1 (en) 2011-04-12 2014-10-09 Quanterix Corporation Methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury
EP2732289B1 (en) * 2011-07-13 2018-04-11 Acumen Pharmaceuticals, Inc. ANTIBODIES, KIT AND in vitro METHOD FOR DETECTING AMYLOID BETA OLIGOMERS
JP6231263B2 (ja) * 2012-07-17 2017-11-15 株式会社島津製作所 アフィニティ支持体及びそれを用いた物質の捕捉方法
RS61717B1 (sr) 2014-07-10 2021-05-31 Bioarctic Ab Poboljšana antitela koja vezuju a-beta protofibril
WO2018156180A1 (en) 2017-02-24 2018-08-30 Kindred Biosciences, Inc. Anti-il31 antibodies for veterinary use
WO2021055670A1 (en) 2019-09-20 2021-03-25 Avx Corporation Somatic cell-based electrical biosensor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994017197A1 (fr) * 1993-01-25 1994-08-04 Takeda Chemical Industries, Ltd. ANTICORPS DIRIGE CONTRE LE β-AMYLOIDE OU UN DERIVE DE CE DERNIER ET SON UTILISATION
US5786180A (en) * 1995-02-14 1998-07-28 Bayer Corporation Monoclonal antibody 369.2B specific for β A4 peptide
US20030068316A1 (en) * 1997-02-05 2003-04-10 Klein William L. Anti-ADDL antibodies and uses thereof
NZ337765A (en) * 1997-04-09 2001-09-28 Mindset Biopharmaceuticals Usa Recombinant antibodies having specificity for beta-amyloid N-terminus and C-terminus and use in treating Alzheimer's Disease
WO2004031400A2 (en) * 2002-10-01 2004-04-15 Northwestern University Amyloid beta-derived diffusible ligands (addls), addl-surrogates, addl-binding molecules, and uses thereof
TWI374893B (en) * 2003-05-30 2012-10-21 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
NZ554725A (en) * 2004-10-25 2009-10-30 Merck & Co Inc Anti-ADDL antibodies and uses thereof

Similar Documents

Publication Publication Date Title
JP2009519895A5 (enExample)
KR102385495B1 (ko) 항-cd71 활성화 가능한 항체 약물 접합체 및 이의 사용 방법
RU2007119382A (ru) Антитела против addl и их применение
RU2008120027A (ru) Анти-addl моноклональное антитело и его применение
JP2013542914A5 (enExample)
KR102349370B1 (ko) 인간화 또는 친화도 성숙된 항 앤지오포이에틴-2 항체 및 그의 용도
JP2020526478A5 (enExample)
CN104507964B (zh) P2x7受体拮抗剂和激动剂
AU2016258988A1 (en) Anti-ITGa3 antibodies, activatable anti-ITGa3 antibodies, and methods of use thereof
JP2016020389A5 (enExample)
JP2011528561A5 (enExample)
JP2011523550A5 (enExample)
WO2014052462A2 (en) Activatable antibodies that bind interleukin-6 receptor and methods of use thereof
RU2015126533A (ru) Анти-cd47 антитела и способы их применения
JP2013500941A5 (enExample)
FI3553084T3 (fi) Anti-adrenomedulliinivasta-aine (ADM) tai anti-ADM-vasta-ainefragmentti tai anti-ADM-non-Ig-skaffoldi elimen toimintahäiriön tai elimen vajaatoiminnan ehkäisemiseksi tai pienentämiseksi kroonisen tai akuutin taudin tai akuutin tilan omaavassa potilaassa
JP2023509790A (ja) α4β7インテグリン拮抗薬で炎症性腸疾患を治療するための方法
MD3191511T2 (ro) Lianți TNF îmbunătățiți
US10487114B2 (en) Methods for administering peptides for the generation of effective c/s conformation-specific antibodies to a human subject in need thereof
US8883153B2 (en) Methods for preventing and treating angioedema
KR102599010B1 (ko) 항-herv-k 엔벨로프 항체 및 그 용도
US10208108B2 (en) Antibodies directed to ricin toxin
CN112601550B (zh) 抗-乙型淀粉样蛋白抗体及其用途
MX2014006265A (es) Administacion del anticuerpo alfa4beta7 hetero-dimero-especifico.
CN108484765B (zh) 一种抗人α-防御素-1单克隆抗体及其应用