JP2009519705A5 - - Google Patents
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- JP2009519705A5 JP2009519705A5 JP2008540686A JP2008540686A JP2009519705A5 JP 2009519705 A5 JP2009519705 A5 JP 2009519705A5 JP 2008540686 A JP2008540686 A JP 2008540686A JP 2008540686 A JP2008540686 A JP 2008540686A JP 2009519705 A5 JP2009519705 A5 JP 2009519705A5
- Authority
- JP
- Japan
- Prior art keywords
- pore
- nucleotide
- individual nucleotides
- sequence
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002773 nucleotide Substances 0.000 claims 15
- 125000003729 nucleotide group Chemical group 0.000 claims 15
- 239000011148 porous material Substances 0.000 claims 13
- 238000000034 method Methods 0.000 claims 12
- 230000003993 interaction Effects 0.000 claims 4
- 150000007523 nucleic acids Chemical group 0.000 claims 4
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 3
- 229920002477 rna polymer Polymers 0.000 claims 3
- 108091005703 transmembrane proteins Proteins 0.000 claims 3
- 102000035160 transmembrane proteins Human genes 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 2
- 102000053602 DNA Human genes 0.000 claims 2
- 108060002716 Exonuclease Proteins 0.000 claims 2
- 102000013165 exonuclease Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 238000012163 sequencing technique Methods 0.000 claims 2
- 101710092462 Alpha-hemolysin Proteins 0.000 claims 1
- 229920000858 Cyclodextrin Polymers 0.000 claims 1
- 108091028664 Ribonucleotide Proteins 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000005547 deoxyribonucleotide Substances 0.000 claims 1
- 125000002637 deoxyribonucleotide group Chemical group 0.000 claims 1
- 239000001177 diphosphate Substances 0.000 claims 1
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 claims 1
- 235000011180 diphosphates Nutrition 0.000 claims 1
- 150000004712 monophosphates Chemical class 0.000 claims 1
- 239000002336 ribonucleotide Substances 0.000 claims 1
- 125000002652 ribonucleotide group Chemical group 0.000 claims 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims 1
- 239000001226 triphosphate Substances 0.000 claims 1
- 235000011178 triphosphate Nutrition 0.000 claims 1
- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0523282.2A GB0523282D0 (en) | 2005-11-15 | 2005-11-15 | Methods using pores |
| GB0523282.2 | 2005-11-15 | ||
| PCT/GB2006/004265 WO2007057668A1 (en) | 2005-11-15 | 2006-11-15 | Methods using pores |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009519705A JP2009519705A (ja) | 2009-05-21 |
| JP2009519705A5 true JP2009519705A5 (https=) | 2010-01-07 |
| JP5328362B2 JP5328362B2 (ja) | 2013-10-30 |
Family
ID=35516986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008540686A Active JP5328362B2 (ja) | 2005-11-15 | 2006-11-15 | 細孔を使用する方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8105846B2 (https=) |
| EP (2) | EP2272981B1 (https=) |
| JP (1) | JP5328362B2 (https=) |
| KR (1) | KR20080083281A (https=) |
| CN (1) | CN101356288B (https=) |
| AT (1) | ATE545712T1 (https=) |
| AU (1) | AU2006314296B2 (https=) |
| BR (1) | BRPI0618391A2 (https=) |
| CA (1) | CA2629009C (https=) |
| GB (1) | GB0523282D0 (https=) |
| IL (1) | IL191319A (https=) |
| MY (1) | MY149161A (https=) |
| NZ (1) | NZ568163A (https=) |
| RU (1) | RU2008123842A (https=) |
| UA (1) | UA95087C2 (https=) |
| WO (1) | WO2007057668A1 (https=) |
Families Citing this family (90)
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| GB0523282D0 (en) | 2005-11-15 | 2005-12-21 | Isis Innovation | Methods using pores |
| WO2009020682A2 (en) | 2007-05-08 | 2009-02-12 | The Trustees Of Boston University | Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof |
| GB2453377A (en) * | 2007-10-05 | 2009-04-08 | Isis Innovation | Transmembrane protein pores and molecular adapters therefore. |
| US20110229877A1 (en) | 2008-07-07 | 2011-09-22 | Oxford Nanopore Technologies Limited | Enzyme-pore constructs |
| EP2310534B1 (en) * | 2008-07-07 | 2018-09-05 | Oxford Nanopore Technologies Limited | Base-detecting pore |
| US8426807B2 (en) * | 2008-08-01 | 2013-04-23 | Brown University | System and methods for determining molecules using mass spectrometry and related techniques |
| GB0820927D0 (en) * | 2008-11-14 | 2008-12-24 | Isis Innovation | Method |
| WO2010062903A2 (en) * | 2008-11-26 | 2010-06-03 | Board Of Regents, The University Of Texas System | Genomic sequencing using modified protein pores and ionic liquids |
| KR20110125226A (ko) | 2009-01-30 | 2011-11-18 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 혼성화 링커 |
| EP2391732B1 (en) * | 2009-01-30 | 2015-05-27 | Oxford Nanopore Technologies Limited | Methods using adaptors for nucleic acid constructs in transmembrane sequencing |
| GB0905140D0 (en) * | 2009-03-25 | 2009-05-06 | Isis Innovation | Method |
| US8986928B2 (en) | 2009-04-10 | 2015-03-24 | Pacific Biosciences Of California, Inc. | Nanopore sequencing devices and methods |
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| EP2483680A4 (en) | 2009-09-30 | 2014-01-01 | Quantapore Inc | ULTRASOUND SEQUENCING OF BIOLOGICAL POLYMERS WITH THE HELP OF A MARKED NANOPORE |
| US9127313B2 (en) | 2009-12-01 | 2015-09-08 | Oxford Nanopore Technologies Limited | Biochemical analysis instrument |
| US9005425B2 (en) | 2010-03-05 | 2015-04-14 | University Of Utah Research Foundation | Detection of nucleic acid lesions and adducts using nanopores |
| GB2490846A (en) * | 2010-03-05 | 2012-11-14 | Univ Utah Res Found | Detection of nucleic acid lesions and adducts using nanopores |
| US8652779B2 (en) | 2010-04-09 | 2014-02-18 | Pacific Biosciences Of California, Inc. | Nanopore sequencing using charge blockade labels |
| WO2012042226A2 (en) | 2010-10-01 | 2012-04-05 | Oxford Nanopore Technologies Limited | Biochemical analysis apparatus and rotary valve |
| US8673757B2 (en) | 2010-10-28 | 2014-03-18 | International Business Machines Corporation | Structure and method for using high-k material as an etch stop layer in dual stress layer process |
| KR101939420B1 (ko) | 2011-02-11 | 2019-01-16 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 돌연변이체 세공 |
| EP4737389A2 (en) | 2011-05-27 | 2026-05-06 | Oxford Nanopore Technologies PLC | Coupling method |
| RU2467218C1 (ru) * | 2011-06-16 | 2012-11-20 | Закрытое Акционерное Общество "Научно-производственное объединение "Гидравлические аппараты" (ЗАО "НПО "Гидроаппарат") | Гидромуфта |
| EP3318872A1 (en) | 2011-07-20 | 2018-05-09 | The Regents of the University of California | Dual-pore device |
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| IN2014DN06796A (https=) | 2012-02-15 | 2015-05-22 | Oxford Nanopore Tech Ltd | |
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| EP2310534B1 (en) * | 2008-07-07 | 2018-09-05 | Oxford Nanopore Technologies Limited | Base-detecting pore |
| CA2774710C (en) | 2008-09-22 | 2016-08-02 | University Of Washington | Msp nanopores and related methods |
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2005
- 2005-11-15 GB GBGB0523282.2A patent/GB0523282D0/en not_active Ceased
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