JP2009519041A5 - - Google Patents
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- JP2009519041A5 JP2009519041A5 JP2008545768A JP2008545768A JP2009519041A5 JP 2009519041 A5 JP2009519041 A5 JP 2009519041A5 JP 2008545768 A JP2008545768 A JP 2008545768A JP 2008545768 A JP2008545768 A JP 2008545768A JP 2009519041 A5 JP2009519041 A5 JP 2009519041A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- probe
- linker
- target nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 33
- 108020004707 nucleic acids Proteins 0.000 claims 30
- 102000039446 nucleic acids Human genes 0.000 claims 30
- 125000003729 nucleotide group Chemical group 0.000 claims 29
- 239000000523 sample Substances 0.000 claims 28
- 239000000126 substance Substances 0.000 claims 18
- 239000002773 nucleotide Substances 0.000 claims 13
- 239000003795 chemical substances by application Substances 0.000 claims 12
- 230000000379 polymerizing effect Effects 0.000 claims 11
- 230000000295 complement effect Effects 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 108020004635 Complementary DNA Proteins 0.000 claims 5
- 239000012985 polymerization agent Substances 0.000 claims 5
- 239000013615 primer Substances 0.000 claims 5
- -1 nucleotide triphosphate analog Chemical class 0.000 claims 4
- 239000000758 substrate Substances 0.000 claims 4
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 3
- 108091034117 Oligonucleotide Proteins 0.000 claims 3
- 230000003993 interaction Effects 0.000 claims 3
- 238000000926 separation method Methods 0.000 claims 3
- 238000012163 sequencing technique Methods 0.000 claims 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 2
- 102000053602 DNA Human genes 0.000 claims 2
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 claims 2
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 239000002073 nanorod Substances 0.000 claims 2
- 238000003786 synthesis reaction Methods 0.000 claims 2
- 239000003155 DNA primer Substances 0.000 claims 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 claims 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 claims 1
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 claims 1
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 claims 1
- 102100034343 Integrase Human genes 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 238000006116 polymerization reaction Methods 0.000 claims 1
- 230000002441 reversible effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74985805P | 2005-12-12 | 2005-12-12 | |
| US74972905P | 2005-12-12 | 2005-12-12 | |
| PCT/US2006/047534 WO2007070572A2 (en) | 2005-12-12 | 2006-12-12 | Probe for nucleic acid sequencing and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009519041A JP2009519041A (ja) | 2009-05-14 |
| JP2009519041A5 true JP2009519041A5 (https=) | 2010-01-28 |
Family
ID=38051529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008545768A Pending JP2009519041A (ja) | 2005-12-12 | 2006-12-12 | 核酸配列決定のためのプローブおよび使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8344121B2 (https=) |
| EP (2) | EP2311982A1 (https=) |
| JP (1) | JP2009519041A (https=) |
| AT (1) | ATE481505T1 (https=) |
| DE (1) | DE602006016984D1 (https=) |
| WO (2) | WO2007070542A2 (https=) |
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-
2006
- 2006-12-12 DE DE602006016984T patent/DE602006016984D1/de active Active
- 2006-12-12 WO PCT/US2006/047456 patent/WO2007070542A2/en not_active Ceased
- 2006-12-12 US US11/638,160 patent/US8344121B2/en not_active Expired - Fee Related
- 2006-12-12 WO PCT/US2006/047534 patent/WO2007070572A2/en not_active Ceased
- 2006-12-12 US US12/095,973 patent/US7871777B2/en not_active Expired - Fee Related
- 2006-12-12 EP EP10176710A patent/EP2311982A1/en not_active Withdrawn
- 2006-12-12 AT AT06847604T patent/ATE481505T1/de not_active IP Right Cessation
- 2006-12-12 EP EP06847604A patent/EP1960550B1/en not_active Ceased
- 2006-12-12 JP JP2008545768A patent/JP2009519041A/ja active Pending
-
2010
- 2010-12-29 US US12/980,802 patent/US20110111975A1/en not_active Abandoned
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