JP2009517048A5 - - Google Patents
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- JP2009517048A5 JP2009517048A5 JP2008542433A JP2008542433A JP2009517048A5 JP 2009517048 A5 JP2009517048 A5 JP 2009517048A5 JP 2008542433 A JP2008542433 A JP 2008542433A JP 2008542433 A JP2008542433 A JP 2008542433A JP 2009517048 A5 JP2009517048 A5 JP 2009517048A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- oligoribonucleotide
- composition
- nucleotide linker
- separated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108091027075 5S-rRNA precursor Proteins 0.000 claims 12
- 239000002773 nucleotide Substances 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 108091028664 Ribonucleotide Proteins 0.000 claims 3
- 239000002336 ribonucleotide Substances 0.000 claims 3
- 125000002652 ribonucleotide group Chemical group 0.000 claims 3
- LDGWQMRUWMSZIU-LQDDAWAPSA-M 2,3-bis[(z)-octadec-9-enoxy]propyl-trimethylazanium;chloride Chemical compound [Cl-].CCCCCCCC\C=C/CCCCCCCCOCC(C[N+](C)(C)C)OCCCCCCCC\C=C/CCCCCCCC LDGWQMRUWMSZIU-LQDDAWAPSA-M 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 230000004048 modification Effects 0.000 claims 2
- 238000012986 modification Methods 0.000 claims 2
- 239000003981 vehicle Substances 0.000 claims 2
- RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical compound [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73952905P | 2005-11-25 | 2005-11-25 | |
| US77898906P | 2006-03-03 | 2006-03-03 | |
| PCT/US2006/045183 WO2007062107A2 (en) | 2005-11-25 | 2006-11-22 | Immunostimulatory oligoribonucleotides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009517048A JP2009517048A (ja) | 2009-04-30 |
| JP2009517048A5 true JP2009517048A5 (https=) | 2010-01-14 |
| JP4538522B2 JP4538522B2 (ja) | 2010-09-08 |
Family
ID=37946151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008542433A Active JP4538522B2 (ja) | 2005-11-25 | 2006-11-22 | 免疫刺激性オリゴリボヌクレオチド |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US7662949B2 (https=) |
| EP (2) | EP1957647B1 (https=) |
| JP (1) | JP4538522B2 (https=) |
| KR (1) | KR20080072934A (https=) |
| CN (1) | CN102517292B (https=) |
| AU (2) | AU2006318464B2 (https=) |
| BR (2) | BRPI0622298A8 (https=) |
| CA (1) | CA2630738C (https=) |
| DK (1) | DK1957647T3 (https=) |
| ES (1) | ES2536103T3 (https=) |
| HK (1) | HK1210212A1 (https=) |
| PL (1) | PL1957647T3 (https=) |
| PT (1) | PT1957647E (https=) |
| SI (1) | SI1957647T1 (https=) |
| TW (1) | TW200738877A (https=) |
| WO (1) | WO2007062107A2 (https=) |
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-
2006
- 2006-11-22 JP JP2008542433A patent/JP4538522B2/ja active Active
- 2006-11-22 CA CA2630738A patent/CA2630738C/en active Active
- 2006-11-22 PL PL06838257T patent/PL1957647T3/pl unknown
- 2006-11-22 PT PT68382571T patent/PT1957647E/pt unknown
- 2006-11-22 SI SI200631904T patent/SI1957647T1/sl unknown
- 2006-11-22 AU AU2006318464A patent/AU2006318464B2/en not_active Ceased
- 2006-11-22 KR KR1020087015356A patent/KR20080072934A/ko not_active Ceased
- 2006-11-22 EP EP06838257.1A patent/EP1957647B1/en active Active
- 2006-11-22 BR BRPI0622298A patent/BRPI0622298A8/pt not_active Application Discontinuation
- 2006-11-22 BR BRPI0618857-5A patent/BRPI0618857B1/pt not_active IP Right Cessation
- 2006-11-22 US US11/603,978 patent/US7662949B2/en active Active
- 2006-11-22 EP EP15150854.6A patent/EP2883957A1/en not_active Withdrawn
- 2006-11-22 DK DK06838257T patent/DK1957647T3/en active
- 2006-11-22 WO PCT/US2006/045183 patent/WO2007062107A2/en not_active Ceased
- 2006-11-22 CN CN201110430925.6A patent/CN102517292B/zh not_active Expired - Fee Related
- 2006-11-22 ES ES06838257.1T patent/ES2536103T3/es active Active
- 2006-11-23 TW TW095143354A patent/TW200738877A/zh unknown
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