JP2009517015A - 組換えポリペプチドならびにｔｓｈレセプターに対する自己抗体を検出及び／又は定量化する方法 - Google Patents
組換えポリペプチドならびにｔｓｈレセプターに対する自己抗体を検出及び／又は定量化する方法 Download PDFInfo
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- 239000011534 wash buffer Substances 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/24—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Public Health (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73802105P | 2005-11-21 | 2005-11-21 | |
| PCT/IB2006/003394 WO2007057778A2 (en) | 2005-11-21 | 2006-11-21 | Recombinant polypeptides and methods for detecting and/or quantifying autoantibodies against tsh receptor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009517015A true JP2009517015A (ja) | 2009-04-30 |
| JP2009517015A5 JP2009517015A5 (enExample) | 2010-01-14 |
Family
ID=37998447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008541846A Withdrawn JP2009517015A (ja) | 2005-11-21 | 2006-11-21 | 組換えポリペプチドならびにｔｓｈレセプターに対する自己抗体を検出及び／又は定量化する方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20080305098A1 (enExample) |
| EP (2) | EP1951753A2 (enExample) |
| JP (1) | JP2009517015A (enExample) |
| WO (1) | WO2007057778A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011136911A (ja) * | 2009-12-25 | 2011-07-14 | Tosoh Corp | 甲状腺刺激ホルモンレセプターの安定化方法 |
| JP2016527304A (ja) * | 2013-08-06 | 2016-09-08 | アピトープ インターナショナル エヌブイ | ペプチド |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010075194A1 (en) * | 2008-12-22 | 2010-07-01 | St. Jude Children's Research Hospital | Prokaryotic expression of soluble, active dkk |
| PL2617734T3 (pl) * | 2008-12-24 | 2016-01-29 | Rsr Ltd | Ludzkie przeciwciała przeciwko TSHR |
| US20130189707A1 (en) * | 2010-01-26 | 2013-07-25 | Svetlana Alexandrovna Sergeeva | Method of determination of autoantibody level by means of enzyme immunoassay |
| US8986937B2 (en) | 2011-09-09 | 2015-03-24 | Quidel Corporation | Compositions and methods for detecting autoantibodies |
| EP2997039B1 (en) | 2013-05-14 | 2019-06-26 | Siemens Healthcare Diagnostics Inc. | Stabilized liquid formulations containing receptors |
| JP7117847B2 (ja) * | 2014-12-24 | 2022-08-15 | アピトープ インターナショナル エヌブイ | 組成物 |
| CN114601913B (zh) * | 2022-03-09 | 2025-03-04 | 陕西慧普德泰生物科技有限责任公司 | 人TSHR A亚基在预防Graves病中的应用 |
| CN119192331A (zh) * | 2024-11-11 | 2024-12-27 | 郑州伊美诺生物技术有限公司 | 促甲状腺激素受体的突变体及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030022826A1 (en) * | 1987-09-08 | 2003-01-30 | Duke University | Use of synthetic peptides to induce tolerance to pathogenic T and B cell epitopes of autoantigens or infectious agents |
| JPH0789991A (ja) * | 1993-09-28 | 1995-04-04 | Mitsubishi Chem Corp | 新規なポリペプチドおよびそれを用いるｔｓｈ受容体抗体の測定法 |
| EP1078986B1 (en) | 1999-08-24 | 2007-02-28 | Tosoh Corporation | Secretory thyroid stimulating hormone receptor (TSHR), and method for assaying anti-TSHR antibody using the same |
| ES2736165T3 (es) * | 2001-08-23 | 2019-12-26 | Rsr Ltd | Regiones epítopo de un receptor de tirotropina (TSH), sus usos y anticuerpos para las mismas |
| DK2383296T3 (en) * | 2002-11-29 | 2017-05-22 | Rsr Ltd | Antibody of the thyrotropin receptor and its applications |
-
2006
- 2006-11-21 EP EP06820995A patent/EP1951753A2/en not_active Withdrawn
- 2006-11-21 US US12/094,533 patent/US20080305098A1/en not_active Abandoned
- 2006-11-21 EP EP09005494A patent/EP2080772A3/en not_active Withdrawn
- 2006-11-21 JP JP2008541846A patent/JP2009517015A/ja not_active Withdrawn
- 2006-11-21 WO PCT/IB2006/003394 patent/WO2007057778A2/en not_active Ceased
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011136911A (ja) * | 2009-12-25 | 2011-07-14 | Tosoh Corp | 甲状腺刺激ホルモンレセプターの安定化方法 |
| JP2016527304A (ja) * | 2013-08-06 | 2016-09-08 | アピトープ インターナショナル エヌブイ | ペプチド |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007057778A3 (en) | 2007-11-08 |
| WO2007057778A2 (en) | 2007-05-24 |
| EP1951753A2 (en) | 2008-08-06 |
| EP2080772A3 (en) | 2009-10-07 |
| US20080305098A1 (en) | 2008-12-11 |
| EP2080772A2 (en) | 2009-07-22 |
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