JP2009516518A - 2種の活性鎖を有する多標的干渉rnaならびにそれらの設計および使用方法 - Google Patents
2種の活性鎖を有する多標的干渉rnaならびにそれらの設計および使用方法 Download PDFInfo
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| US9212363B2 (en) * | 2012-05-11 | 2015-12-15 | City Of Hope | RNAI molecules with non-watson crick pairing based on artificial mutation consensus sequences to counter escape mutations |
| WO2013173638A1 (en) | 2012-05-16 | 2013-11-21 | Rana Therapeutics, Inc. | Compositions and methods for modulating smn gene family expression |
| US10837014B2 (en) | 2012-05-16 | 2020-11-17 | Translate Bio Ma, Inc. | Compositions and methods for modulating SMN gene family expression |
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| JP2015518712A (ja) | 2012-05-16 | 2015-07-06 | ラナ セラピューティクス インコーポレイテッド | Mecp2発現を調節するための組成物及び方法 |
| CN104583401A (zh) | 2012-05-16 | 2015-04-29 | Rana医疗有限公司 | 用于调节atp2a2表达的组合物和方法 |
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| AU2016270913A1 (en) | 2015-06-03 | 2018-01-04 | Monsanto Technology Llc | Methods and compositions for introducing nucleic acids into plants |
| WO2017015671A1 (en) | 2015-07-23 | 2017-01-26 | Arcturus Therapeutics, Inc. | Compositions for treating amyloidosis |
| EP3337899A1 (en) * | 2015-08-21 | 2018-06-27 | Universitätsklinikum Jena | Human micrornas for treatment of malignant tumours |
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| WO2003070912A2 (en) * | 2001-06-06 | 2003-08-28 | Sirna Therapeutics, Inc. | RNA INTERFERENCE MEDIATED INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
| US20050048529A1 (en) * | 2002-02-20 | 2005-03-03 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA) |
| US20050209180A1 (en) * | 2001-05-18 | 2005-09-22 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of hepatitis C virus (HCV) expression using short interfering nucleic acid (siNA) |
| US20050187174A1 (en) * | 2001-05-18 | 2005-08-25 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA) |
| WO2004065549A2 (en) * | 2003-01-17 | 2004-08-05 | University Of Florida | Small interference rna gene therapy |
| US7893034B2 (en) * | 2004-09-02 | 2011-02-22 | Yale University | Regulation of oncogenes by microRNAs |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2005019453A2 (en) * | 2001-05-18 | 2005-03-03 | Sirna Therapeutics, Inc. | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) |
| WO2005028649A1 (en) * | 2002-02-20 | 2005-03-31 | Sirna Therapeutics, Inc. | RNA INTERFERENCE MEDIATED INHIBITION OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
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| AU2006315102A1 (en) | 2007-05-24 |
| AU2006315099B2 (en) | 2012-07-05 |
| US8097715B2 (en) | 2012-01-17 |
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| CA2630932A1 (en) | 2007-05-24 |
| AU2006315099C1 (en) | 2013-01-10 |
| AU2006315099A1 (en) | 2007-05-24 |
| US20090192103A1 (en) | 2009-07-30 |
| WO2007056826A1 (en) | 2007-05-24 |
| EP1951263A1 (en) | 2008-08-06 |
| US20090239816A1 (en) | 2009-09-24 |
| EP1951736A4 (en) | 2009-12-16 |
| EP1951263A4 (en) | 2009-11-18 |
| CA2630952A1 (en) | 2007-05-24 |
| JP2009516517A (ja) | 2009-04-23 |
| JP5078904B2 (ja) | 2012-11-21 |
| EP1951736A1 (en) | 2008-08-06 |
| WO2007056829A1 (en) | 2007-05-24 |
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