JP2009516518A5 - - Google Patents

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Publication number
JP2009516518A5
JP2009516518A5 JP2008541543A JP2008541543A JP2009516518A5 JP 2009516518 A5 JP2009516518 A5 JP 2009516518A5 JP 2008541543 A JP2008541543 A JP 2008541543A JP 2008541543 A JP2008541543 A JP 2008541543A JP 2009516518 A5 JP2009516518 A5 JP 2009516518A5
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JP
Japan
Prior art keywords
rna molecules
specificity
regulate
expression
manufactured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2008541543A
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English (en)
Japanese (ja)
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JP2009516518A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/AU2006/001750 external-priority patent/WO2007056829A1/en
Publication of JP2009516518A publication Critical patent/JP2009516518A/ja
Publication of JP2009516518A5 publication Critical patent/JP2009516518A5/ja
Ceased legal-status Critical Current

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JP2008541543A 2005-11-21 2006-11-21 ２種の活性鎖を有する多標的干渉ｒｎａならびにそれらの設計および使用方法 Ceased JP2009516518A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73864005P 2005-11-21 2005-11-21
US73844105P 2005-11-21 2005-11-21
PCT/AU2006/001750 WO2007056829A1 (en) 2005-11-21 2006-11-21 Multitargeting interfering rnas having two active strands and methods for their design and use

Publications (2)

Publication Number Publication Date
JP2009516518A JP2009516518A (ja) 2009-04-23
JP2009516518A5 true JP2009516518A5 (enExample) 2012-07-26

Family

ID=38048226

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008541543A Ceased JP2009516518A (ja) 2005-11-21 2006-11-21 ２種の活性鎖を有する多標的干渉ｒｎａならびにそれらの設計および使用方法
JP2008541541A Expired - Fee Related JP5078904B2 (ja) 2005-11-21 2006-11-21 多標的干渉ｒｎａならびにそれらの使用および設計方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008541541A Expired - Fee Related JP5078904B2 (ja) 2005-11-21 2006-11-21 多標的干渉ｒｎａならびにそれらの使用および設計方法

Country Status (6)

Country Link
US (3) US20070269815A1 (enExample)
EP (2) EP1951263A4 (enExample)
JP (2) JP2009516518A (enExample)
AU (2) AU2006315099C1 (enExample)
CA (2) CA2630952A1 (enExample)
WO (2) WO2007056829A1 (enExample)

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US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
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US9212363B2 (en) * 2012-05-11 2015-12-15 City Of Hope RNAI molecules with non-watson crick pairing based on artificial mutation consensus sequences to counter escape mutations
CN104583402A (zh) 2012-05-16 2015-04-29 Rana医疗有限公司 用于调节mecp2表达的组合物和方法
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US10837014B2 (en) 2012-05-16 2020-11-17 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
JP2015523854A (ja) 2012-05-16 2015-08-20 ラナ セラピューティクス インコーポレイテッド Ｓｍｎ遺伝子ファミリー発現を調節するための組成物及び方法
US10174315B2 (en) 2012-05-16 2019-01-08 The General Hospital Corporation Compositions and methods for modulating hemoglobin gene family expression
CN104619843B (zh) 2012-05-24 2020-03-06 A.B.种子有限公司 用于使基因表达沉默的组合物和方法
US9163235B2 (en) 2012-06-21 2015-10-20 MiRagen Therapeutics, Inc. Inhibitors of the miR-15 family of micro-RNAs
US20150247141A1 (en) 2012-09-14 2015-09-03 Rana Therapeutics, Inc. Multimeric oligonucleotide compounds
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
WO2014107763A1 (en) * 2013-01-08 2014-07-17 Benitec Biopharma Limited Age-related macular degeneration treatment
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EP3052632A4 (en) 2013-10-04 2017-03-29 Rana Therapeutics, Inc. Compositions and methods for treating amyotrophic lateral sclerosis
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UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
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JP6752151B2 (ja) * 2014-03-25 2020-09-09 アークトゥラス・セラピューティクス・インコーポレイテッドＡｒｃｔｕｒｕｓ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 遺伝子サイレンシングにおいて低下したｏｆｆ−ｔａｒｇｅｔ効果を有するｕｎａオリゴマー
JP6771387B2 (ja) 2014-03-25 2020-10-21 アークトゥラス・セラピューティクス・インコーポレイテッドＡｒｃｔｕｒｕｓ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 遺伝子サイレンシング用トランスサイレチン対立遺伝子選択的ｕｎａオリゴマー
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EP3420809A1 (en) 2014-04-01 2019-01-02 Monsanto Technology LLC Compositions and methods for controlling insect pests
US10988764B2 (en) * 2014-06-23 2021-04-27 Monsanto Technology Llc Compositions and methods for regulating gene expression via RNA interference
EP3161138A4 (en) 2014-06-25 2017-12-06 Monsanto Technology LLC Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
CN114009454A (zh) 2014-07-29 2022-02-08 孟山都技术公司 用于控制昆虫害虫的组合物和方法
HK1244035A1 (en) 2014-12-15 2018-07-27 Bonac Corporation Single-stranded nucleic acid molecule for inhibiting tgf- beta 1 expression
RU2723049C2 (ru) 2015-01-22 2020-06-08 Монсанто Текнолоджи Ллс Композиции и способы борьбы с leptinotarsa
US10519447B2 (en) 2015-04-01 2019-12-31 Arcturus Therapeutics, Inc. Therapeutic UNA oligomers and uses thereof
US10883103B2 (en) 2015-06-02 2021-01-05 Monsanto Technology Llc Compositions and methods for delivery of a polynucleotide into a plant
US10655136B2 (en) 2015-06-03 2020-05-19 Monsanto Technology Llc Methods and compositions for introducing nucleic acids into plants
WO2017015671A1 (en) 2015-07-23 2017-01-26 Arcturus Therapeutics, Inc. Compositions for treating amyloidosis
EP3337899A1 (en) * 2015-08-21 2018-06-27 Universitätsklinikum Jena Human micrornas for treatment of malignant tumours
EP3618634A4 (en) * 2017-05-01 2021-07-21 Donald Danforth Plant Science Center RNA-BASED APPROACH TO PLANT PROTECTION
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AU2022299474A1 (en) * 2021-06-23 2023-12-21 Versameb Ag Compositions and methods for modulating expression of genes

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US20050209180A1 (en) * 2001-05-18 2005-09-22 Sirna Therapeutics, Inc. RNA interference mediated inhibition of hepatitis C virus (HCV) expression using short interfering nucleic acid (siNA)
WO2003070912A2 (en) * 2001-06-06 2003-08-28 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
EP1627061B1 (en) * 2001-05-18 2009-08-12 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA)
US20050048529A1 (en) * 2002-02-20 2005-03-03 Sirna Therapeutics, Inc. RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
US20050187174A1 (en) * 2001-05-18 2005-08-25 Sirna Therapeutics, Inc. RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
US20050148530A1 (en) * 2002-02-20 2005-07-07 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
CA2513679A1 (en) * 2003-01-17 2004-08-05 University Of Florida Small interference rna gene therapy
DK1797183T3 (da) * 2004-09-02 2012-10-01 Univ Yale Regulering af onkogener med mikrornas

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