JP2009516517A5 - - Google Patents

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Publication number
JP2009516517A5
JP2009516517A5 JP2008541541A JP2008541541A JP2009516517A5 JP 2009516517 A5 JP2009516517 A5 JP 2009516517A5 JP 2008541541 A JP2008541541 A JP 2008541541A JP 2008541541 A JP2008541541 A JP 2008541541A JP 2009516517 A5 JP2009516517 A5 JP 2009516517A5
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JP
Japan
Prior art keywords
rna molecules
specificity
manufactured
done
sequences present
Prior art date
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JP2008541541A
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English (en)
Japanese (ja)
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JP2009516517A (ja
JP5078904B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/AU2006/001741 external-priority patent/WO2007056826A1/en
Publication of JP2009516517A publication Critical patent/JP2009516517A/ja
Publication of JP2009516517A5 publication Critical patent/JP2009516517A5/ja
Application granted granted Critical
Publication of JP5078904B2 publication Critical patent/JP5078904B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2008541541A 2005-11-21 2006-11-21 多標的干渉rnaならびにそれらの使用および設計方法 Expired - Fee Related JP5078904B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US73844105P 2005-11-21 2005-11-21
US73864005P 2005-11-21 2005-11-21
US60/738,640 2005-11-21
US60/738,441 2005-11-21
PCT/AU2006/001741 WO2007056826A1 (en) 2005-11-21 2006-11-21 Multitargeting interfering rnas and methods of their use and design

Publications (3)

Publication Number Publication Date
JP2009516517A JP2009516517A (ja) 2009-04-23
JP2009516517A5 true JP2009516517A5 (enExample) 2012-07-26
JP5078904B2 JP5078904B2 (ja) 2012-11-21

Family

ID=38048226

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008541541A Expired - Fee Related JP5078904B2 (ja) 2005-11-21 2006-11-21 多標的干渉rnaならびにそれらの使用および設計方法
JP2008541543A Ceased JP2009516518A (ja) 2005-11-21 2006-11-21 2種の活性鎖を有する多標的干渉rnaならびにそれらの設計および使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008541543A Ceased JP2009516518A (ja) 2005-11-21 2006-11-21 2種の活性鎖を有する多標的干渉rnaならびにそれらの設計および使用方法

Country Status (6)

Country Link
US (3) US20070269815A1 (enExample)
EP (2) EP1951263A4 (enExample)
JP (2) JP5078904B2 (enExample)
AU (2) AU2006315102A1 (enExample)
CA (2) CA2630932A1 (enExample)
WO (2) WO2007056829A1 (enExample)

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US20100022618A1 (en) 2007-09-05 2010-01-28 Dong Liang Long interfering nucleic acid duplexes targeting multiple RNA targets
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
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AU2010259295B2 (en) 2009-06-10 2015-05-07 Temasek Life Sciences Laboratory Limited Virus induced gene silencing (VIGS) for functional analysis of genes in cotton.
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
US20130023578A1 (en) * 2009-12-31 2013-01-24 Samyang Biopharmaceuticals Corporation siRNA for inhibition of c-Met expression and anticancer composition containing the same
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MX377067B (es) 2011-09-13 2025-03-07 Monsanto Technology Llc Métodos y composiciones para el control de malezas.
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
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US9580708B2 (en) 2011-09-14 2017-02-28 Rana Therapeutics, Inc. Multimeric oligonucleotides compounds
JP6280045B2 (ja) * 2011-12-22 2018-02-14 アイオーニス ファーマシューティカルズ, インコーポレーテッドIonis Pharmaceuticals,Inc. 肺腺癌内転移関連性転写物1(metastasis−associated−in−lung−adenocarcinoma−transcript−1:malat−1)の発現調節法
US9212363B2 (en) * 2012-05-11 2015-12-15 City Of Hope RNAI molecules with non-watson crick pairing based on artificial mutation consensus sequences to counter escape mutations
BR112014028634A2 (pt) 2012-05-16 2017-06-27 Rana Therapeutics Inc composições e métodos para modulação da expressão de utrn
CA2873769A1 (en) 2012-05-16 2013-11-21 Rana Therapeutics Inc. Compositions and methods for modulating hemoglobin gene family expression
BR112014028644A2 (pt) 2012-05-16 2017-08-15 Rana Therapeutics Inc Composições e métodos para modulação da expressão de atp2a2
AU2013262709A1 (en) 2012-05-16 2015-01-22 Rana Therapeutics, Inc. Compositions and methods for modulating MECP2 expression
US10837014B2 (en) 2012-05-16 2020-11-17 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
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AR091143A1 (es) 2012-05-24 2015-01-14 Seeds Ltd Ab Composiciones y metodos para silenciar la expresion genetica
US9163235B2 (en) 2012-06-21 2015-10-20 MiRagen Therapeutics, Inc. Inhibitors of the miR-15 family of micro-RNAs
EP2895200B1 (en) 2012-09-14 2019-11-06 Translate Bio MA, Inc. Multimeric oligonucleotide compounds
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
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EP2971185A4 (en) 2013-03-13 2017-03-08 Monsanto Technology LLC Methods and compositions for weed control
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JP6726105B2 (ja) 2014-12-15 2020-07-22 株式会社ボナック TGF−β1発現抑制のための一本鎖核酸分子
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MX2021010152A (es) 2019-02-27 2021-09-14 Ionis Pharmaceuticals Inc Moduladores de la expresion de malat1.
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US20050187174A1 (en) * 2001-05-18 2005-08-25 Sirna Therapeutics, Inc. RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
US20050148530A1 (en) * 2002-02-20 2005-07-07 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
WO2003070912A2 (en) * 2001-06-06 2003-08-28 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
US20050048529A1 (en) * 2002-02-20 2005-03-03 Sirna Therapeutics, Inc. RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
AU2004266311B2 (en) * 2001-05-18 2009-07-23 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
EP1590002A4 (en) * 2003-01-17 2007-02-28 Univ Florida siRNA GENE THERAPY
JP2008511678A (ja) * 2004-09-02 2008-04-17 イェール ユニバーシティ マイクロrnaによるオンコジーンの調節

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