JP2009514840A - インフルエンザワクチンによってプライム（ｐｒｉｍｉｎｇ）／ブースト（ｂｏｏｓｔｉｎｇ）するための投与経路 - Google Patents

インフルエンザワクチンによってプライム（ｐｒｉｍｉｎｇ）／ブースト（ｂｏｏｓｔｉｎｇ）するための投与経路 Download PDF

Info

Publication number
JP2009514840A
JP2009514840A JP2008538419A JP2008538419A JP2009514840A JP 2009514840 A JP2009514840 A JP 2009514840A JP 2008538419 A JP2008538419 A JP 2008538419A JP 2008538419 A JP2008538419 A JP 2008538419A JP 2009514840 A JP2009514840 A JP 2009514840A
Authority
JP
Japan
Prior art keywords
vaccine
influenza
mucosal
parenteral
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008538419A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009514840A5 (enExample
Inventor
マイケル バジディ，
デレック オハガン，
Original Assignee
ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル filed Critical ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル
Publication of JP2009514840A publication Critical patent/JP2009514840A/ja
Publication of JP2009514840A5 publication Critical patent/JP2009514840A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2008538419A 2005-11-04 2006-11-06 インフルエンザワクチンによってプライム（ｐｒｉｍｉｎｇ）／ブースト（ｂｏｏｓｔｉｎｇ）するための投与経路 Pending JP2009514840A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73402605P 2005-11-04 2005-11-04
US83633206P 2006-08-07 2006-08-07
PCT/GB2006/004132 WO2007052057A2 (en) 2005-11-04 2006-11-06 Adminstration routes for priming/boosting with influenza vaccines

Publications (2)

Publication Number Publication Date
JP2009514840A true JP2009514840A (ja) 2009-04-09
JP2009514840A5 JP2009514840A5 (enExample) 2009-10-15

Family

ID=37862714

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008538419A Pending JP2009514840A (ja) 2005-11-04 2006-11-06 インフルエンザワクチンによってプライム（ｐｒｉｍｉｎｇ）／ブースト（ｂｏｏｓｔｉｎｇ）するための投与経路

Country Status (7)

Country Link
US (1) US20100158943A1 (enExample)
EP (1) EP1945253A2 (enExample)
JP (1) JP2009514840A (enExample)
AU (1) AU2006310338A1 (enExample)
CA (1) CA2628379A1 (enExample)
NZ (1) NZ567980A (enExample)
WO (1) WO2007052057A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016502995A (ja) * 2012-12-17 2016-02-01 ユーロシネ ヴァクシンズ アクチエボラーグ 鼻腔内予防接種投薬レジメン

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101500603A (zh) 2006-06-15 2009-08-05 诺华有限公司 节省佐剂的多剂量流感疫苗接种方案
WO2009016639A2 (en) 2007-08-02 2009-02-05 Biondvax Pharmaceuticals Ltd. Multimeric multiepitope influenza vaccines
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
US8668904B2 (en) 2007-12-06 2014-03-11 Glaxosmithkline Biologicals S.A. Influenza composition
JP5518041B2 (ja) * 2008-03-18 2014-06-11 ノバルティス アーゲー インフルエンザウイルスワクチン抗原の調製における改良
EP2310045A1 (en) 2008-06-25 2011-04-20 Novartis AG Rapid responses to delayed booster immunisations
WO2010092476A1 (en) 2009-02-10 2010-08-19 Novartis Ag Influenza vaccine regimens for pandemic-associated strains
EA023662B1 (ru) 2009-02-10 2016-06-30 Новартис Аг Вакцины против гриппа со сниженным количеством сквалена
US9707288B2 (en) * 2010-07-22 2017-07-18 John W. Schrader Cross-protective pathogen protection, methods and compositions thereof
US9821051B1 (en) 2010-10-28 2017-11-21 Seqirus UK Limited Reducing hospitalization in elderly influenza vaccine recipients
WO2012114323A1 (en) * 2011-02-22 2012-08-30 Biondvax Pharmaceuticals Ltd. Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines
US10335435B2 (en) 2015-05-22 2019-07-02 Marco Merida Method for endoscopically delivering stem cells to the brain using an intranasal, injectable approach
KR20180035807A (ko) 2015-06-26 2018-04-06 세퀴러스 유케이 리미티드 항원적으로 매치된 인플루엔자 백신
WO2019086463A1 (en) 2017-10-30 2019-05-09 Baxalta GmbH Environmentally compatible detergents for inactivation of lipid-enveloped viruses

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10500099A (ja) * 1993-12-22 1998-01-06 カイロン エセ．ピー．アー． 非毒性の粘膜アジュバント
JP2003509473A (ja) * 1999-09-24 2003-03-11 スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム ワクチン
JP2003510291A (ja) * 1999-09-30 2003-03-18 スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム 新規組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500513A (en) * 1979-05-15 1985-02-19 Miles Laboratories, Inc. Influenza vaccine production in liquid cell culture
US5643574A (en) * 1993-10-04 1997-07-01 Albany Medical College Protein- or peptide-cochleate vaccines and methods of immunizing using the same
US6818222B1 (en) * 1997-03-21 2004-11-16 Chiron Corporation Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
CA2514667C (en) * 2003-01-30 2013-01-08 Chiron Corporation Adjuvanted influenza vaccine
WO2004073652A2 (en) * 2003-02-20 2004-09-02 Becton Dickinson And Company Powder formulations of recombinant staphylococcal enterotoxin b (rseb) made by atmospheric spray-freeze drying for improved vaccination

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10500099A (ja) * 1993-12-22 1998-01-06 カイロン エセ．ピー．アー． 非毒性の粘膜アジュバント
JP2003509473A (ja) * 1999-09-24 2003-03-11 スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム ワクチン
JP2003510291A (ja) * 1999-09-30 2003-03-18 スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム 新規組成物

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6012017838; Ｈａｓｈｉｇｕｃｃｉ，　Ｋ．　ｅｔ　ａｌ．: Ｖａｃｃｉｎｅ Ｖｏｌ．１４，　Ｎｏ．２, 1996, ｐｐ．１１３-１１９ *
JPN6012017840; Ａｓａｎｕｍａ，　Ｈ．　ｅｔ　ａｌ．: Ｖａｃｃｉｎｅ Ｖｏｌ．１３，　Ｎｏ．１, 1995, ｐｐ．３-５ *
JPN6012017843; Ｌｅｅ，　Ｃ．Ｋ．　ｅｔ　ａｌ．: Ｖａｃｃｉｎｅ Ｖｏｌ．１７, 1999, ｐｐ．３０７２-３０８２ *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016502995A (ja) * 2012-12-17 2016-02-01 ユーロシネ ヴァクシンズ アクチエボラーグ 鼻腔内予防接種投薬レジメン
JP2018172434A (ja) * 2012-12-17 2018-11-08 ユーロシネ ヴァクシンズ アクチエボラーグ 鼻腔内予防接種投薬レジメン

Also Published As

Publication number Publication date
US20100158943A1 (en) 2010-06-24
WO2007052057A3 (en) 2007-07-12
CA2628379A1 (en) 2007-05-10
NZ567980A (en) 2012-01-12
WO2007052057A2 (en) 2007-05-10
EP1945253A2 (en) 2008-07-23
AU2006310338A1 (en) 2007-05-10

Similar Documents

Publication Publication Date Title
JP7427648B2 (ja) 卵を使用しないインフルエンザウイルスワクチンの作製
JP5566687B2 (ja) アジュバントを使用しない複数回投与ワクチン接種レジメン
JP5957176B2 (ja) Ｈ５インフルエンザａ型ウイルスの複数のクレードを使用する予防接種
JP6275229B2 (ja) 血球凝集素およびマトリックスタンパク質を含むインフルエンザウイルスワクチン
JP2018184450A (ja) アジュバントとして減少した量の水中油型エマルションを有するインフルエンザワクチン
JP2010531348A5 (enExample)
JP2010531348A (ja) 添加剤の少ないインフルエンザワクチン
JP2009514841A (ja) 粒子状アジュバントと免疫増強物質との組合せを含むインフルエンザワクチン
JP2011506264A (ja) インフルエンザウイルスの４つの株に由来する抗原を含むワクチン
JP2012167123A (ja) サイトカイン誘導剤を含むアジュバントインフルエンザワクチン
JP5518041B2 (ja) インフルエンザウイルスワクチン抗原の調製における改良
JP2009534303A (ja) 冷蔵しないインフルエンザワクチンの保存
JP2009514844A (ja) スプリットインフルエンザワクチン用のアジュバントとしての遊離水相界面活性剤を含むエマルション
JP5363107B2 (ja) アジュバントを含むスプリットインフルエンザワクチンにおけるｔｈ１／ｔｈ２バランスの変化
JP5005700B2 (ja) アルミニウムアジュバントに即座に吸着されるインフルエンザワクチン
NZ567980A (en) Administration routes (intranasal or mucosal and parenteral or intramuscular) for priming/boosting with influenza vaccines
JP2009514838A (ja) 細胞培養物において増殖されたインフルエンザウイルスから調製された非ビリオン抗原を含むアジュバントワクチン
JP2014015486A (ja) インフルエンザウイルスの４つの株に由来する抗原を含むワクチン

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090825

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090825

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100817

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120406

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120622

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120629

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20121005

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130115

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130403

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130410

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20130924