JP2009514511A5 - - Google Patents
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- Publication number
- JP2009514511A5 JP2009514511A5 JP2008538258A JP2008538258A JP2009514511A5 JP 2009514511 A5 JP2009514511 A5 JP 2009514511A5 JP 2008538258 A JP2008538258 A JP 2008538258A JP 2008538258 A JP2008538258 A JP 2008538258A JP 2009514511 A5 JP2009514511 A5 JP 2009514511A5
- Authority
- JP
- Japan
- Prior art keywords
- whey
- milk
- concentrate
- ultrafiltration
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 claims 15
- 108010046377 Whey Proteins Proteins 0.000 claims 12
- 102000007544 Whey Proteins Human genes 0.000 claims 12
- 239000005862 Whey Substances 0.000 claims 10
- 239000012528 membrane Substances 0.000 claims 10
- 235000008504 concentrate Nutrition 0.000 claims 9
- 239000012141 concentrate Substances 0.000 claims 9
- 235000013365 dairy product Nutrition 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 9
- 238000000108 ultra-filtration Methods 0.000 claims 8
- 235000013336 milk Nutrition 0.000 claims 6
- 239000008267 milk Substances 0.000 claims 6
- 210000004080 milk Anatomy 0.000 claims 6
- 238000001728 nano-filtration Methods 0.000 claims 6
- OIZGSVFYNBZVIK-FHHHURIISA-N 3'-sialyllactose Chemical compound O1[C@@H]([C@H](O)[C@H](O)CO)[C@H](NC(=O)C)[C@@H](O)C[C@@]1(C(O)=O)O[C@@H]1[C@@H](O)[C@H](O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)O[C@H](CO)[C@@H]1O OIZGSVFYNBZVIK-FHHHURIISA-N 0.000 claims 5
- 239000012465 retentate Substances 0.000 claims 5
- 239000012466 permeate Substances 0.000 claims 4
- 239000000047 product Substances 0.000 claims 4
- 238000001035 drying Methods 0.000 claims 3
- 235000013350 formula milk Nutrition 0.000 claims 3
- 235000016709 nutrition Nutrition 0.000 claims 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- 241000282849 Ruminantia Species 0.000 claims 2
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 claims 2
- 239000000969 carrier Substances 0.000 claims 2
- 239000005018 casein Substances 0.000 claims 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims 2
- 235000021240 caseins Nutrition 0.000 claims 2
- 235000015872 dietary supplement Nutrition 0.000 claims 2
- 235000020218 follow-on milk formula Nutrition 0.000 claims 2
- 235000013305 food Nutrition 0.000 claims 2
- 235000011868 grain product Nutrition 0.000 claims 2
- 239000008101 lactose Substances 0.000 claims 2
- 230000035764 nutrition Effects 0.000 claims 2
- 229920001542 oligosaccharide Polymers 0.000 claims 2
- 150000002482 oligosaccharides Chemical class 0.000 claims 2
- 235000018102 proteins Nutrition 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 238000001223 reverse osmosis Methods 0.000 claims 2
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 claims 2
- 235000020183 skimmed milk Nutrition 0.000 claims 2
- 235000014268 sports nutrition Nutrition 0.000 claims 2
- 235000020209 toddler milk formula Nutrition 0.000 claims 2
- 235000021119 whey protein Nutrition 0.000 claims 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 229920002774 Maltodextrin Polymers 0.000 claims 1
- 239000005913 Maltodextrin Substances 0.000 claims 1
- 229920000881 Modified starch Polymers 0.000 claims 1
- 239000004952 Polyamide Substances 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- 238000004587 chromatography analysis Methods 0.000 claims 1
- 238000009295 crossflow filtration Methods 0.000 claims 1
- 238000002425 crystallisation Methods 0.000 claims 1
- 230000008025 crystallization Effects 0.000 claims 1
- 238000011026 diafiltration Methods 0.000 claims 1
- 239000000835 fiber Substances 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 235000021125 infant nutrition Nutrition 0.000 claims 1
- 230000006651 lactation Effects 0.000 claims 1
- 229940035034 maltodextrin Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 239000012452 mother liquor Substances 0.000 claims 1
- 229920002647 polyamide Polymers 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 235000008939 whole milk Nutrition 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73320405P | 2005-11-04 | 2005-11-04 | |
| PCT/DK2006/000607 WO2007051475A1 (en) | 2005-11-04 | 2006-11-03 | A concentrate derived from a milk product enriched in naturally occurring sialyllactose and a process for preparation thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013098460A Division JP5944860B2 (ja) | 2005-11-04 | 2013-05-08 | 天然のシアリルラクトースに富んだ、乳製品由来の濃縮物及び、その調製方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009514511A JP2009514511A (ja) | 2009-04-09 |
| JP2009514511A5 true JP2009514511A5 (https=) | 2009-12-24 |
Family
ID=37607077
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008538258A Withdrawn JP2009514511A (ja) | 2005-11-04 | 2006-11-03 | 天然のシアリルラクトースを濃縮した、乳製品由来の濃縮物及び、その調製方法 |
| JP2013098460A Active JP5944860B2 (ja) | 2005-11-04 | 2013-05-08 | 天然のシアリルラクトースに富んだ、乳製品由来の濃縮物及び、その調製方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013098460A Active JP5944860B2 (ja) | 2005-11-04 | 2013-05-08 | 天然のシアリルラクトースに富んだ、乳製品由来の濃縮物及び、その調製方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20070104843A1 (https=) |
| EP (1) | EP1951060B1 (https=) |
| JP (2) | JP2009514511A (https=) |
| CN (1) | CN101299924A (https=) |
| AR (1) | AR056761A1 (https=) |
| AU (1) | AU2006310880B2 (https=) |
| BR (1) | BRPI0618261A2 (https=) |
| CA (1) | CA2628225C (https=) |
| DK (1) | DK1951060T3 (https=) |
| EA (1) | EA017195B1 (https=) |
| IL (1) | IL191179A (https=) |
| NZ (1) | NZ568653A (https=) |
| WO (1) | WO2007051475A1 (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA103180C2 (ru) * | 2007-11-26 | 2013-09-25 | Нестек С.А. | Сбалансированная по возрасту система питания для детей |
| NL2001377C2 (nl) * | 2008-03-14 | 2009-09-15 | Friesland Brands Bv | Werkwijze voor het isoleren van siaalzuur bevattende oligosachariden, alsmede de hiermee verkrijgbare siaalzuur bevattende oligosachariden bevatttende samenstellingen. |
| JP2012510476A (ja) * | 2008-12-02 | 2012-05-10 | プロラクタ バイオサイエンス,インコーポレイテッド | ヒト乳透過組成物ならびにその製造および使用方法 |
| GB2468670A (en) * | 2009-03-17 | 2010-09-22 | Separation Technologies Invest | Processing whey or raw milk |
| GB0904562D0 (en) * | 2009-03-17 | 2009-04-29 | Separation Technologies Invest | Isolation and purification of components of whey |
| JP5641598B2 (ja) * | 2009-09-29 | 2014-12-17 | 雪印メグミルク株式会社 | シアリルラクトース素材の分離方法 |
| JP5599994B2 (ja) * | 2009-09-29 | 2014-10-01 | 雪印メグミルク株式会社 | シアリルラクトース素材の分離方法 |
| AU2010311316B2 (en) * | 2009-10-28 | 2015-03-12 | Valio Ltd | Whey protein product and a method for its preparation |
| BR112013015951A2 (en) | 2010-12-31 | 2018-07-10 | Abbott Laboratories | nutritional compositions comprising human milk oligosaccharides and nucleotides and uses thereof to treat and / or prevent enteric viral infection. |
| US11337990B2 (en) | 2010-12-31 | 2022-05-24 | Abbott Laboratories | Human milk oligosaccharides to promote growth of beneficial bacteria |
| ES2708924T3 (es) | 2010-12-31 | 2019-04-12 | Abbott Lab | Procedimientos de uso de oligosacáridos de la leche humana para mejorar la salud respiratoria de las vías respiratorias |
| MY180910A (en) | 2010-12-31 | 2020-12-11 | Abbott Lab | Methods for reducing the incidence of oxidative stress using human milk oligosaccharides, vitamin c and anti-inflammatory agents |
| MY197622A (en) | 2010-12-31 | 2023-06-28 | Abbott Lab | Methods for decreasing the incidence of necrotizing enterocolitis in infants, toddlers, or children using human milk oligosaccharides |
| WO2012092157A2 (en) | 2010-12-31 | 2012-07-05 | Abbott Laboratories | Nutritional formulations including human milk oligosaccharides and antioxidants and uses thereof |
| EP3338784B1 (en) | 2010-12-31 | 2020-07-22 | Abbott Laboratories | Human milk oligosaccharides for modulating inflammation |
| CA2825697A1 (en) † | 2011-02-10 | 2012-08-16 | Nestec S.A. | Modulation of growth of bifidobacteria using a combination of oligosaccharides found in human milk |
| FI124323B (fi) | 2011-02-18 | 2014-06-30 | Valio Oy | Maitopohjainen tuote ja menetelmä sen valmistamiseksi |
| DK2734210T3 (en) | 2011-07-22 | 2018-01-22 | Abbott Lab | GALACTOOLIGOSACCHARIDES FOR THE PREVENTION OF DAMAGE TO AND / OR PROMOTION OF HEALING OF THE MAVE GAS CHANNEL |
| SG2014013478A (en) | 2011-08-29 | 2014-05-29 | Abbott Lab | Human milk oligosaccharides for preventing injury and/or promoting healing of the gastrointestinal tract |
| NL2007931C2 (en) * | 2011-12-07 | 2013-06-10 | Friesland Brands Bv | Methods for providing sialylated oligosaccharides and products obtainable thereby. |
| EP2638810A1 (en) * | 2012-03-15 | 2013-09-18 | N.V. Nutricia | Process for preparing infant formula |
| MX2015002290A (es) * | 2012-08-21 | 2015-10-09 | Gervais Danone Sa | Una composicion alimenticia que comprende una mezcla de permeado lacteo y harina vegetal. |
| US10709770B2 (en) | 2013-07-31 | 2020-07-14 | Mead Johnson Nutrition Company | Nutritional compositions containing a prebiotic and lactoferrin and uses thereof |
| US9609888B2 (en) | 2013-07-31 | 2017-04-04 | Mead Johnson Nutrition Company | Nutritional compositions containing synergistic combination and uses thereof |
| EP2885977A1 (en) | 2013-12-19 | 2015-06-24 | Agriculture and Food Development Authority (TEAGASC) | An oligosaccharide-enriched composition having immune-modulatory and anti-adhesion properties |
| JP5812455B2 (ja) * | 2014-07-15 | 2015-11-11 | 雪印メグミルク株式会社 | シアリルラクトース素材の分離方法 |
| US10582714B2 (en) | 2015-07-10 | 2020-03-10 | Mead Johnson Nutrition Company | Nutritional compositions and methods for promoting cognitive development |
| US10617701B2 (en) | 2015-07-10 | 2020-04-14 | Mead Johnson Nutrition Company | Nutritional compositions containing phosphatidylethanolamine, sphingomyelin and docosahexaenoic acid |
| EP3393632A1 (en) * | 2015-12-21 | 2018-10-31 | Tetra Laval Holdings & Finance S.A. | System and process for increasing solids content of skim milk or whey |
| KR20230006028A (ko) | 2016-06-21 | 2023-01-10 | 아를라 푸즈 에이엠비에이 | 우유 단백질 및 우유 당류를 함유하는 개선된 영양 제품의 제조 방법 및 상기 방법에 의해 수득된 제품 |
| SG10202100843TA (en) | 2016-07-28 | 2021-03-30 | Fonterra Cooperative Group Ltd | Dairy product and process |
| EP3300606A1 (de) * | 2016-09-28 | 2018-04-04 | DMK Deutsches Milchkontor GmbH | Aufschäumbare milchzubereitung |
| FI129799B (en) | 2017-06-16 | 2022-08-31 | Valio Oy | Buttermilk |
| US11214588B2 (en) | 2017-06-30 | 2022-01-04 | Glycom A/S | Synthesis of oligosaccharides |
| WO2019212704A1 (en) | 2018-05-02 | 2019-11-07 | Fairlife, Llc | Production and separation of milk fractions with diafiltration |
| GB2573539A (en) | 2018-05-09 | 2019-11-13 | Mjn Us Holdings Llc | Wellbeing supplement for postpartum maternal nutrition |
| GB201909888D0 (en) | 2019-07-10 | 2019-08-21 | Dairy Crest Ltd | Methods for manufacturing comestible products |
| DE102019120026A1 (de) * | 2019-07-24 | 2021-01-28 | Molkerei Alois Müller GmbH & Co. KG | Verfahren zum Herstellen von Milchprodukten und mit solchen Verfahren hergestellte Milchprodukte |
| TW202126317A (zh) | 2019-09-24 | 2021-07-16 | 美商普拉塔生技公司 | 用於治療發炎和免疫疾病之組成物和方法 |
| WO2022155126A1 (en) * | 2021-01-12 | 2022-07-21 | Intrinsic Medicine, Inc. | Methods and compositions for supporting human health during space travel |
| EP4042875B1 (en) * | 2021-02-15 | 2025-07-30 | Rakesh Kumar Aggarwal | A human milk fortifier |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0631286B2 (ja) * | 1987-12-24 | 1994-04-27 | 雪印乳業株式会社 | シアル酸類含有組成物の製造法 |
| US6020015A (en) | 1988-09-22 | 2000-02-01 | Gaull; Gerald E. | Infant formula compositions and nutrition containing genetically engineered human milk proteins |
| US5270452A (en) * | 1988-11-28 | 1993-12-14 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Pure glia maturation factor |
| JPH0710875B2 (ja) * | 1989-03-10 | 1995-02-08 | 雪印乳業株式会社 | シアル酸類含有脱塩乳糖の製造方法 |
| JP2802654B2 (ja) * | 1989-10-30 | 1998-09-24 | 雪印乳業株式会社 | ホエーの脱塩時に生ずる陰イオン交換樹脂のアルカリ洗浄廃液からのオリゴ糖結合型シアル酸類の回収方法 |
| JP3035833B2 (ja) * | 1991-01-21 | 2000-04-24 | 雪印乳業株式会社 | シアル酸類含有組成物の製造方法 |
| JP3044487B2 (ja) * | 1991-02-28 | 2000-05-22 | 雪印乳業株式会社 | シアル酸類を含有しα−ラクトアルブミン含有量の高い組成物の製造方法 |
| DE4313908A1 (de) | 1993-04-28 | 1994-11-03 | Huels Chemische Werke Ag | Wasserenthärtende Formulierungen |
| JP3501415B2 (ja) * | 1994-03-30 | 2004-03-02 | 雪印乳業株式会社 | ビフィズス菌および乳酸菌増殖促進剤 |
| US5575916A (en) * | 1994-11-07 | 1996-11-19 | Neose Pharmaceuticals, Inc. | Method of processing a cheese processing waste stream |
| JP3143351B2 (ja) | 1995-03-07 | 2001-03-07 | シャープ株式会社 | 反射型光結合装置 |
| JP2997419B2 (ja) | 1996-05-31 | 2000-01-11 | 雪印乳業株式会社 | 脳ガングリオシド含量減少抑制剤 |
| JP3552856B2 (ja) * | 1996-09-27 | 2004-08-11 | 雪印乳業株式会社 | 栄養強化組成物 |
| NZ328836A (en) | 1996-10-09 | 1999-02-25 | Nestle Sa | Process for demineralization of sweet whey by electrodeionization in an apparatus containing dilution and concentration departments |
| CN1242776A (zh) * | 1996-10-10 | 2000-01-26 | 尼澳斯技术股份有限公司 | 用超滤、反渗透和纳滤纯化糖类 |
| HUP0001634A2 (hu) | 1996-10-10 | 2000-09-28 | Cytel Corporation | Szénhidrátok tisztítása ultraszűréssel, fordított ozmózissal és nanoszűréssel |
| US6323008B1 (en) * | 1997-08-14 | 2001-11-27 | Neose Technologies, Inc. | Methods for producing sialyloligosaccharides in a dairy source |
| EP1255449B2 (en) * | 2000-02-17 | 2016-06-08 | Nestec S.A. | Nutritional formulation containing prebiotic substances |
| US6630452B2 (en) * | 2000-02-17 | 2003-10-07 | Wyeth | Nutritional formulation containing prebiotic substances |
| US6875459B2 (en) * | 2001-09-10 | 2005-04-05 | Henry B. Kopf | Method and apparatus for separation of milk, colostrum, and whey |
| EP1549151A1 (en) * | 2002-10-11 | 2005-07-06 | Wyeth | Nutritional formulations containing synbiotic substances |
| US7867541B2 (en) * | 2003-04-14 | 2011-01-11 | Mead Johnson Nutrition Company | Compositions and methods of formulation for enteral formulas containing sialic acid |
| JP4465164B2 (ja) | 2003-06-20 | 2010-05-19 | 株式会社ヤクルト本社 | シアル酸含有オリゴ糖の製造方法 |
| EP1643862A1 (en) | 2003-06-24 | 2006-04-12 | University of Kansas Medical Center | Infant formula |
| JP4316450B2 (ja) | 2004-09-02 | 2009-08-19 | 古河電気工業株式会社 | ネットワーク中継装置、ネットワークシステム及び暗号化通信方法 |
| ES2781328T3 (es) | 2005-02-21 | 2020-09-01 | Nestle Sa | Mezcla de oligosacáridos |
-
2006
- 2006-11-03 DK DK06805547.4T patent/DK1951060T3/da active
- 2006-11-03 AU AU2006310880A patent/AU2006310880B2/en active Active
- 2006-11-03 BR BRPI0618261-5A patent/BRPI0618261A2/pt not_active Application Discontinuation
- 2006-11-03 EP EP06805547.4A patent/EP1951060B1/en active Active
- 2006-11-03 WO PCT/DK2006/000607 patent/WO2007051475A1/en not_active Ceased
- 2006-11-03 AR ARP060104824A patent/AR056761A1/es active IP Right Grant
- 2006-11-03 EA EA200801252A patent/EA017195B1/ru not_active IP Right Cessation
- 2006-11-03 CA CA2628225A patent/CA2628225C/en active Active
- 2006-11-03 NZ NZ568653A patent/NZ568653A/en unknown
- 2006-11-03 US US11/592,219 patent/US20070104843A1/en not_active Abandoned
- 2006-11-03 CN CNA200680041000XA patent/CN101299924A/zh active Pending
- 2006-11-03 JP JP2008538258A patent/JP2009514511A/ja not_active Withdrawn
-
2008
- 2008-05-01 IL IL191179A patent/IL191179A/en active IP Right Grant
-
2011
- 2011-01-31 US US12/929,532 patent/US8445053B2/en active Active
-
2013
- 2013-05-08 JP JP2013098460A patent/JP5944860B2/ja active Active
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