JP2009513118A5 - - Google Patents
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- Publication number
- JP2009513118A5 JP2009513118A5 JP2008537015A JP2008537015A JP2009513118A5 JP 2009513118 A5 JP2009513118 A5 JP 2009513118A5 JP 2008537015 A JP2008537015 A JP 2008537015A JP 2008537015 A JP2008537015 A JP 2008537015A JP 2009513118 A5 JP2009513118 A5 JP 2009513118A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- polypeptide
- synaptic vesicle
- bont
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005051789.7A DE102005051789B4 (de) | 2005-10-28 | 2005-10-28 | Der Botulinus Neurotoxin A Proteinrezeptor und seine Anwendungen |
| PCT/EP2006/010420 WO2007048638A2 (de) | 2005-10-28 | 2006-10-30 | Der botulinus neurotoxin a proteinrezeptor und seine anwendungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009513118A JP2009513118A (ja) | 2009-04-02 |
| JP2009513118A5 true JP2009513118A5 (https=) | 2009-11-05 |
Family
ID=37770829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008537015A Pending JP2009513118A (ja) | 2005-10-28 | 2006-10-30 | ボツリヌス神経毒ａタンパク質受容体およびその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8476024B2 (https=) |
| EP (1) | EP1940874B1 (https=) |
| JP (1) | JP2009513118A (https=) |
| KR (1) | KR20080068069A (https=) |
| AT (1) | ATE539088T1 (https=) |
| AU (1) | AU2006308122B2 (https=) |
| CA (1) | CA2627457C (https=) |
| DE (1) | DE102005051789B4 (https=) |
| ES (1) | ES2379513T3 (https=) |
| NZ (1) | NZ567312A (https=) |
| WO (1) | WO2007048638A2 (https=) |
| ZA (1) | ZA200803403B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004043009A1 (de) | 2004-09-06 | 2006-03-23 | Toxogen Gmbh | Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen |
| DE102005019302A1 (de) * | 2005-04-26 | 2006-11-16 | Toxogen Gmbh | Carrier zum Targeting von Nervenzellen |
| US7985554B2 (en) | 2005-10-14 | 2011-07-26 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin A receptor and the use thereof |
| WO2009008916A2 (en) | 2007-03-22 | 2009-01-15 | The Regents Of The University Of Californina | Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins |
| US9000131B2 (en) * | 2008-07-31 | 2015-04-07 | The Regents Of The University Of California | Antibodies that neutralize botulinum neurotoxins |
| US8771707B2 (en) * | 2008-09-30 | 2014-07-08 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin E receptors and uses thereof |
| US9243057B2 (en) | 2010-08-31 | 2016-01-26 | The Regents Of The University Of California | Antibodies for botulinum neurotoxins |
| UA116985C2 (uk) | 2012-05-30 | 2018-06-11 | Президент Енд Феллоуз Оф Гарвард Колледж | Рекомбінантний ботулінічний нейротоксин |
| WO2014079495A1 (en) * | 2012-11-21 | 2014-05-30 | Syntaxin Limited | Methods for the manufacture of proteolytically processed polypeptides |
| PT3274364T (pt) | 2015-03-26 | 2021-11-05 | Harvard College | Neurotoxina botulínica manipulada |
| KR101670188B1 (ko) | 2015-11-09 | 2016-10-27 | 충북대학교 산학협력단 | 보툴리눔 신경독소 ｅ형에 특이적인 폴리펩타이드 및 이의 용도 |
| EP3504226A1 (en) | 2016-08-24 | 2019-07-03 | President and Fellows of Harvard College | Engineered botulinum neurotoxin |
| KR102480965B1 (ko) | 2016-09-13 | 2022-12-26 | 알레간 인코포레이티드 | 안정화된 비단백질 클로스트리듐 독소 조성물 |
| KR101958312B1 (ko) * | 2017-09-06 | 2019-07-02 | 국방과학연구소 | 보툴리눔 a형 독소에 대한 항체 |
| IL272002A (en) | 2020-01-13 | 2021-07-29 | The Israel Institute Of Biological Res Iibr | Methods for identifying anti clostridial neurotoxin compounds |
| WO2023210585A1 (ja) * | 2022-04-25 | 2023-11-02 | 株式会社Jiksak Bioengineering | 標的化剤 |
| WO2025089343A1 (ja) * | 2023-10-25 | 2025-05-01 | 株式会社Jiksak Bioengineering | 抗シナプス小胞糖タンパク質２ｃ抗体 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005016233A2 (en) | 2002-10-31 | 2005-02-24 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin b receptors and use thereof |
| CA2484115C (en) * | 2002-12-03 | 2007-01-30 | Ucb, S.A. | Methods for the identification of agents for the treatment of seizures, neurological diseases, endocrinopathies and hormonal diseases |
| US7985554B2 (en) * | 2005-10-14 | 2011-07-26 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin A receptor and the use thereof |
-
2005
- 2005-10-28 DE DE102005051789.7A patent/DE102005051789B4/de not_active Expired - Fee Related
-
2006
- 2006-10-30 JP JP2008537015A patent/JP2009513118A/ja active Pending
- 2006-10-30 AT AT06806613T patent/ATE539088T1/de active
- 2006-10-30 AU AU2006308122A patent/AU2006308122B2/en not_active Ceased
- 2006-10-30 US US12/084,074 patent/US8476024B2/en active Active
- 2006-10-30 ES ES06806613T patent/ES2379513T3/es active Active
- 2006-10-30 NZ NZ567312A patent/NZ567312A/en not_active IP Right Cessation
- 2006-10-30 WO PCT/EP2006/010420 patent/WO2007048638A2/de not_active Ceased
- 2006-10-30 KR KR1020087011531A patent/KR20080068069A/ko not_active Ceased
- 2006-10-30 CA CA2627457A patent/CA2627457C/en active Active
- 2006-10-30 EP EP06806613A patent/EP1940874B1/de not_active Not-in-force
-
2008
- 2008-04-17 ZA ZA200803403A patent/ZA200803403B/xx unknown
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