JP2009513118A - ボツリヌス神経毒aタンパク質受容体およびその使用 - Google Patents
ボツリヌス神経毒aタンパク質受容体およびその使用 Download PDFInfo
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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| DE102005051789.7A DE102005051789B4 (de) | 2005-10-28 | 2005-10-28 | Der Botulinus Neurotoxin A Proteinrezeptor und seine Anwendungen |
| PCT/EP2006/010420 WO2007048638A2 (de) | 2005-10-28 | 2006-10-30 | Der botulinus neurotoxin a proteinrezeptor und seine anwendungen |
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| JP2009513118A true JP2009513118A (ja) | 2009-04-02 |
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| EP (1) | EP1940874B1 (https=) |
| JP (1) | JP2009513118A (https=) |
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Cited By (1)
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| WO2025089343A1 (ja) * | 2023-10-25 | 2025-05-01 | 株式会社Jiksak Bioengineering | 抗シナプス小胞糖タンパク質2c抗体 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004043009A1 (de) | 2004-09-06 | 2006-03-23 | Toxogen Gmbh | Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen |
| DE102005019302A1 (de) * | 2005-04-26 | 2006-11-16 | Toxogen Gmbh | Carrier zum Targeting von Nervenzellen |
| US7985554B2 (en) | 2005-10-14 | 2011-07-26 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin A receptor and the use thereof |
| WO2009008916A2 (en) | 2007-03-22 | 2009-01-15 | The Regents Of The University Of Californina | Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins |
| US9000131B2 (en) * | 2008-07-31 | 2015-04-07 | The Regents Of The University Of California | Antibodies that neutralize botulinum neurotoxins |
| US8771707B2 (en) * | 2008-09-30 | 2014-07-08 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin E receptors and uses thereof |
| US9243057B2 (en) | 2010-08-31 | 2016-01-26 | The Regents Of The University Of California | Antibodies for botulinum neurotoxins |
| UA116985C2 (uk) | 2012-05-30 | 2018-06-11 | Президент Енд Феллоуз Оф Гарвард Колледж | Рекомбінантний ботулінічний нейротоксин |
| WO2014079495A1 (en) * | 2012-11-21 | 2014-05-30 | Syntaxin Limited | Methods for the manufacture of proteolytically processed polypeptides |
| PT3274364T (pt) | 2015-03-26 | 2021-11-05 | Harvard College | Neurotoxina botulínica manipulada |
| KR101670188B1 (ko) | 2015-11-09 | 2016-10-27 | 충북대학교 산학협력단 | 보툴리눔 신경독소 e형에 특이적인 폴리펩타이드 및 이의 용도 |
| EP3504226A1 (en) | 2016-08-24 | 2019-07-03 | President and Fellows of Harvard College | Engineered botulinum neurotoxin |
| KR102480965B1 (ko) | 2016-09-13 | 2022-12-26 | 알레간 인코포레이티드 | 안정화된 비단백질 클로스트리듐 독소 조성물 |
| KR101958312B1 (ko) * | 2017-09-06 | 2019-07-02 | 국방과학연구소 | 보툴리눔 a형 독소에 대한 항체 |
| IL272002A (en) | 2020-01-13 | 2021-07-29 | The Israel Institute Of Biological Res Iibr | Methods for identifying anti clostridial neurotoxin compounds |
| WO2023210585A1 (ja) * | 2022-04-25 | 2023-11-02 | 株式会社Jiksak Bioengineering | 標的化剤 |
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| WO2005016233A2 (en) | 2002-10-31 | 2005-02-24 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin b receptors and use thereof |
| CA2484115C (en) * | 2002-12-03 | 2007-01-30 | Ucb, S.A. | Methods for the identification of agents for the treatment of seizures, neurological diseases, endocrinopathies and hormonal diseases |
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Patent Citations (1)
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| WO2007050390A2 (en) * | 2005-10-14 | 2007-05-03 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin a receptor and the use thereof |
Non-Patent Citations (2)
| Title |
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| JPN6012000756; J Neurosci., 1998年, 第18巻, 9269-9281ページ * |
| JPN6012000757; STRAUSBERG RL et al., Database GenBank[online], Accession No.NM_014979, <http://www.ncbi.nlm.nih.gov * |
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| WO2025089343A1 (ja) * | 2023-10-25 | 2025-05-01 | 株式会社Jiksak Bioengineering | 抗シナプス小胞糖タンパク質2c抗体 |
Also Published As
| Publication number | Publication date |
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| US8476024B2 (en) | 2013-07-02 |
| AU2006308122B2 (en) | 2011-06-30 |
| NZ567312A (en) | 2011-09-30 |
| EP1940874A2 (de) | 2008-07-09 |
| EP1940874B1 (de) | 2011-12-28 |
| DE102005051789B4 (de) | 2014-08-07 |
| DE102005051789A1 (de) | 2007-05-10 |
| WO2007048638A2 (de) | 2007-05-03 |
| KR20080068069A (ko) | 2008-07-22 |
| US20090252722A1 (en) | 2009-10-08 |
| ZA200803403B (en) | 2009-02-25 |
| CA2627457C (en) | 2014-05-13 |
| WO2007048638A3 (de) | 2007-07-26 |
| CA2627457A1 (en) | 2007-05-03 |
| ES2379513T3 (es) | 2012-04-26 |
| AU2006308122A1 (en) | 2007-05-03 |
| ATE539088T1 (de) | 2012-01-15 |
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