JP2009512682A - 少なくとも1種の抗癌性薬物および少なくとも1種のポリマーを含む医薬組成物 - Google Patents

少なくとも1種の抗癌性薬物および少なくとも1種のポリマーを含む医薬組成物 Download PDF

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JP2009512682A
JP2009512682A JP2008536207A JP2008536207A JP2009512682A JP 2009512682 A JP2009512682 A JP 2009512682A JP 2008536207 A JP2008536207 A JP 2008536207A JP 2008536207 A JP2008536207 A JP 2008536207A JP 2009512682 A JP2009512682 A JP 2009512682A
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composition
novel
cancer
polymer
particles
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JP2009512682A5 (cg-RX-API-DMAC7.html
Inventor
アマルジット シン
サラブジット シン
アジャイ ケー. グプタ
マンゲッシュ エム. クルカルニ
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パナセア バイオテック リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5138Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2008536207A 2005-10-21 2006-10-19 少なくとも1種の抗癌性薬物および少なくとも1種のポリマーを含む医薬組成物 Pending JP2009512682A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1327MU2005 2005-10-21
IN1081MU2006 2006-07-10
PCT/IN2006/000427 WO2007069272A2 (en) 2005-10-21 2006-10-19 Pharmaceutical composition comprising at least one anticancer drug and at least one polymer

Publications (2)

Publication Number Publication Date
JP2009512682A true JP2009512682A (ja) 2009-03-26
JP2009512682A5 JP2009512682A5 (cg-RX-API-DMAC7.html) 2009-11-19

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JP2008536207A Pending JP2009512682A (ja) 2005-10-21 2006-10-19 少なくとも1種の抗癌性薬物および少なくとも1種のポリマーを含む医薬組成物

Country Status (13)

Country Link
US (1) US20100166872A1 (cg-RX-API-DMAC7.html)
EP (1) EP1962906A4 (cg-RX-API-DMAC7.html)
JP (1) JP2009512682A (cg-RX-API-DMAC7.html)
AR (1) AR058130A1 (cg-RX-API-DMAC7.html)
AU (1) AU2006324872B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0617663A2 (cg-RX-API-DMAC7.html)
CA (1) CA2626016A1 (cg-RX-API-DMAC7.html)
CR (1) CR9989A (cg-RX-API-DMAC7.html)
EA (1) EA015781B1 (cg-RX-API-DMAC7.html)
IL (1) IL190882A0 (cg-RX-API-DMAC7.html)
MA (1) MA29946B1 (cg-RX-API-DMAC7.html)
RS (1) RS20080167A (cg-RX-API-DMAC7.html)
WO (1) WO2007069272A2 (cg-RX-API-DMAC7.html)

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JP2013501789A (ja) * 2009-08-10 2013-01-17 ナノパツクス・フアーマ・エル・エル・シー 蛋白質及びペプチドナノ粒子のアンフォールディングとフォールディングを利用した薬剤送達方法
JP2014505672A (ja) * 2010-12-02 2014-03-06 エコシンセティックス リミテッド アプタマーバイオコンジュゲート薬物送達システム
JP2018513105A (ja) * 2015-04-03 2018-05-24 シチュアン ケルン ファーマシューティカル リサーチ インスティテュート カンパニー リミテッド ドセタキセルアルブミンナノ粒子医薬組成物、その調製方法及びその使用
JP2021533194A (ja) * 2018-07-31 2021-12-02 マイクロビオン コーポレーション ビスマス・チオール組成物及び創傷を治療する方法
US12186283B2 (en) 2018-07-31 2025-01-07 Microbion Corporation Bismuth-thiol compositions and methods of use

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EA016434B1 (ru) * 2007-12-24 2012-04-30 Сан Фарма Адвансед Ресёрч Компани Лимитед Нанодисперсия
US8871276B2 (en) 2008-02-11 2014-10-28 Technion Research And Development Foundation Ltd. Beta-casein assemblies for mucosal delivery of therapeutic bioactive agents
US8865222B2 (en) 2008-02-11 2014-10-21 Technion Research And Development Foundation Ltd. Beta-casein assemblies for enrichment of food and beverages and methods of preparation thereof
WO2009101613A1 (en) 2008-02-11 2009-08-20 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Beta-casein assemblies for mucosal delivery of therapeutic bioactive agents
US20110045092A1 (en) * 2008-02-11 2011-02-24 Livney Yoav D Casein particles encapsulating therapeutically active agents and uses thereof
GB0818747D0 (en) * 2008-10-13 2008-11-19 Univ Nottingham Biocompatible responsive materials
EP2266546A1 (en) 2009-06-08 2010-12-29 Advancell Advanced in Vitro Cell Technologies,S.A. Process for the preparation of colloidal systems for the delivery of active compounds
CN102802624A (zh) 2009-06-19 2012-11-28 太阳医药高级研发有限公司 药物的纳米分散体以及它的制备方法
MX348668B (es) * 2009-09-21 2017-06-23 J W Pharmaceutical Corp * Nanopartículas de oxaliplatin y método para prepararlas.
CA2798180A1 (en) 2010-05-03 2011-11-10 Teikoku Pharma Usa, Inc. Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
CN103118669B (zh) * 2010-06-01 2016-01-13 盖斯特里希医药公司 口服药物治疗方法和组合物
WO2012058462A2 (en) * 2010-10-29 2012-05-03 Isis Pharmaceuticals, Inc. Combination therapy for the treatment of cancer
JP6038881B2 (ja) 2011-04-20 2016-12-07 ザ・ユニバーシティ・オブ・シドニー 治療の方法及びそのために有用な剤
EP3238709B1 (en) 2011-04-28 2020-07-01 Platform Brightworks Two, Ltd. Improved parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same
WO2013124867A1 (en) * 2012-02-21 2013-08-29 Amrita Vishwa Vidyapeetham University Polymer - polymer or polymer - protein core - shell nano medicine loaded with multiple drug molecules
BR112014032346A2 (pt) 2012-06-26 2017-06-27 Del Mar Pharmaceuticals métodos para tratamento de malignidades resistentes ao inibidor de tirosina-quinase em pacientes com polimorfismos genéticos ou desregulações de ahi1 mutações empregando dianidrogalactitol, diacetildianidrogalactitol, dibromodulcitol, ou análogos ou derivados destes
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
US10143700B2 (en) 2013-02-19 2018-12-04 Amrita Vishwa Vidyapeetham Nanoparticle formulations for delivering multiple therapeutic agents
JP2016519684A (ja) 2013-04-08 2016-07-07 デニス エム ブラウン 準最適に投与された薬物療法の有効性を改善するための及び/又は副作用を低減するための方法および組成物
SMT201700442T1 (it) 2013-09-16 2017-11-15 Astrazeneca Ab Nanoparticelle polimeriche terapeutiche e metodi per preparare e usare le stesse
KR20150047336A (ko) 2013-10-24 2015-05-04 삼성전자주식회사 나노입자, 이를 제조하는 방법, 및 이의 용도
HUP1300646A2 (en) 2013-11-12 2015-05-28 Druggability Technologies Ip Holdco Jersey Ltd Complexes of fulvestrant and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them
CN103739672B (zh) * 2013-12-31 2015-06-10 威特曼生物科技(南京)有限公司 一种聚乙二醇修饰的抑制vegfr2酪氨酸激酶多肽及其应用
RU2591819C2 (ru) * 2014-03-03 2016-07-20 Закрытое акционерное общество "СКАЙ ЛТД" Способ получения фолликулярного белкового препарата и препарат, полученный данным способом
TW202337477A (zh) 2015-02-01 2023-10-01 美商錫羅斯製藥公司 用於病患口服之含砷高表面積冷凍乾燥組合物
WO2016141167A1 (en) 2015-03-03 2016-09-09 Cureport, Inc. Combination liposomal pharmaceutical formulations
US10736845B2 (en) 2015-03-03 2020-08-11 Cureport Inc. Dual loaded liposomal pharmaceutical formulations
IL285928B2 (en) 2016-05-06 2025-06-01 Eagle Pharmaceuticals Inc Fulvestrant formulations and methods of their use
CN110753541A (zh) * 2017-04-24 2020-02-04 Zy治疗公司 用于体内递送的药物组合物、基本上不溶于水的药理学活性剂的制备方法
WO2019028457A2 (en) * 2017-08-04 2019-02-07 University Of Houston System FORMULATION OF NANOSUSPENSION OF DIETHYLSTILBESTROL INJECTABLE
CA3090303A1 (en) 2018-03-28 2019-10-03 Greenmark Biomedical Inc. Phosphate crosslinked starch nanoparticle and dental treatments
FR3087650B1 (fr) * 2018-10-31 2021-01-29 Bio Even Flavine adenine dinucleotide (fad) pour son utilisation pour la prevention et/ou le traitement de cancer
CN114767879A (zh) * 2022-06-02 2022-07-22 平顶山学院 一种多西紫杉醇恶性肿瘤靶向微球及其制备方法与应用

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JP2003520210A (ja) * 2000-01-05 2003-07-02 イマレックス セラピューティクス, インコーポレイテッド 低い水溶性を有する薬物の送達のための薬学的処方物
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013501789A (ja) * 2009-08-10 2013-01-17 ナノパツクス・フアーマ・エル・エル・シー 蛋白質及びペプチドナノ粒子のアンフォールディングとフォールディングを利用した薬剤送達方法
JP2014505672A (ja) * 2010-12-02 2014-03-06 エコシンセティックス リミテッド アプタマーバイオコンジュゲート薬物送達システム
JP2018513105A (ja) * 2015-04-03 2018-05-24 シチュアン ケルン ファーマシューティカル リサーチ インスティテュート カンパニー リミテッド ドセタキセルアルブミンナノ粒子医薬組成物、その調製方法及びその使用
US11395812B2 (en) 2015-04-03 2022-07-26 Sichuan Kelun Pharmaceutical Research Institute Co. Ltd. Docetaxel albumin nanoparticle pharmaceutical composition, preparation method therefor and use thereof
JP2021533194A (ja) * 2018-07-31 2021-12-02 マイクロビオン コーポレーション ビスマス・チオール組成物及び創傷を治療する方法
US11974978B2 (en) 2018-07-31 2024-05-07 Microbion Corporation Bismuth-thiol compositions and methods for treating wounds
US12036200B2 (en) 2018-07-31 2024-07-16 Microbion Corporation Bismuth-thiol compositions and methods for treating wounds
US12186283B2 (en) 2018-07-31 2025-01-07 Microbion Corporation Bismuth-thiol compositions and methods of use

Also Published As

Publication number Publication date
BRPI0617663A2 (pt) 2011-08-02
EA200801132A1 (ru) 2009-02-27
IL190882A0 (en) 2008-11-03
EP1962906A2 (en) 2008-09-03
EP1962906A4 (en) 2009-11-18
CA2626016A1 (en) 2007-06-21
US20100166872A1 (en) 2010-07-01
WO2007069272A2 (en) 2007-06-21
AU2006324872B2 (en) 2012-03-08
RS20080167A (sr) 2009-07-15
CR9989A (es) 2008-07-18
WO2007069272A3 (en) 2007-08-23
AU2006324872A1 (en) 2007-06-21
AR058130A1 (es) 2008-01-23
EA015781B1 (ru) 2011-12-30
MA29946B1 (fr) 2008-11-03

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