|
US4196265A
(en)
*
|
1977-06-15 |
1980-04-01 |
The Wistar Institute |
Method of producing antibodies
|
|
US4608337A
(en)
*
|
1980-11-07 |
1986-08-26 |
The Wistar Institute |
Human hybridomas and the production of human monoclonal antibodies by human hybridomas
|
|
US5015568A
(en)
*
|
1986-07-09 |
1991-05-14 |
The Wistar Institute |
Diagnostic methods for detecting lymphomas in humans
|
|
US5202429A
(en)
*
|
1986-07-09 |
1993-04-13 |
The Wistar Institute |
DNA molecules having human BCL-2 gene sequences
|
|
US5198338A
(en)
*
|
1989-05-31 |
1993-03-30 |
Temple University |
Molecular probing for human t-cell leukemia and lymphoma
|
|
US6040140A
(en)
*
|
1991-12-11 |
2000-03-21 |
Thomas Jefferson University |
Methods for screening and treating leukemias resulting from all-1 region chromosome abnormalities
|
|
WO1993012136A1
(en)
*
|
1991-12-11 |
1993-06-24 |
Thomas Jefferson University |
Detection and treatment of acute leukemias resulting from chromosome abnormalities in the all-1 region
|
|
US5633135A
(en)
*
|
1991-12-11 |
1997-05-27 |
Thomas Jefferson University |
Chimeric nucleic acids and proteins resulting from ALL-1 region chromosome abnormalities
|
|
US5674682A
(en)
*
|
1992-10-29 |
1997-10-07 |
Thomas Jefferson University |
Nucleic acid primers for detecting micrometastasis of prostate cancer
|
|
EP0667920B1
(en)
*
|
1992-10-29 |
2003-01-15 |
Thomas Jefferson University |
Methods of detecting micrometastasis of prostate cancer
|
|
US7175995B1
(en)
*
|
1994-10-27 |
2007-02-13 |
Thomas Jefferson University |
TCL-1 protein and related methods
|
|
US5985598A
(en)
*
|
1994-10-27 |
1999-11-16 |
Thomas Jefferson University |
TCL-1 gene and protein and related methods and compositions
|
|
US5928884A
(en)
*
|
1996-02-09 |
1999-07-27 |
Croce; Carlo M. |
FHIT proteins and nucleic acids and methods based thereon
|
|
US6242212B1
(en)
*
|
1996-02-09 |
2001-06-05 |
Thomas Jefferson University |
Fragile histidine triad (FHIT) nucleic acids and methods of producing FHIT proteins
|
|
AU6951098A
(en)
*
|
1997-04-04 |
1998-10-30 |
The Texas A & M University System |
Noninvasive detection of colonic biomarkers using fecal messenger rna
|
|
CA2335315A1
(en)
*
|
1998-07-20 |
2000-01-27 |
Thomas Jefferson University |
Nitrilase homologs
|
|
US6255293B1
(en)
*
|
1998-07-24 |
2001-07-03 |
Yeda Research And Development Co., Ltd. |
Prevention of metastasis with 5-aza-2′-deoxycytidine
|
|
US7141417B1
(en)
*
|
1999-02-25 |
2006-11-28 |
Thomas Jefferson University |
Compositions, kits, and methods relating to the human FEZ1 gene, a novel tumor suppressor gene
|
|
US20040132017A1
(en)
|
1999-12-16 |
2004-07-08 |
Robert Richards |
Oxidoreductase gene associated with the fra16d fragile site
|
|
CA2406366A1
(en)
*
|
2000-04-11 |
2001-10-18 |
Thomas Jefferson University |
Muir-torre-like syndrome infhit deficient mice
|
|
US20020086331A1
(en)
*
|
2000-05-16 |
2002-07-04 |
Carlo Croce |
Crystal structure of worm NitFhit reveals that a Nit tetramer binds two Fhit dimers
|
|
US7060811B2
(en)
*
|
2000-10-13 |
2006-06-13 |
Board Of Regents, The University Of Texas System |
WWOX: a tumor suppressor gene mutated in multiple cancers
|
|
US20040033502A1
(en)
*
|
2001-03-28 |
2004-02-19 |
Amanda Williams |
Gene expression profiles in esophageal tissue
|
|
US20050176025A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of B-cell CLL/Lymphoma-2 (BCL-2) gene expression using short interfering nucleic acid (siNA)
|
|
CA2462144C
(en)
*
|
2001-09-28 |
2016-09-20 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Micro-rna molecules
|
|
US7371736B2
(en)
*
|
2001-11-07 |
2008-05-13 |
The Board Of Trustees Of The University Of Arkansas |
Gene expression profiling based identification of DKK1 as a potential therapeutic targets for controlling bone loss
|
|
GB0128898D0
(en)
*
|
2001-12-03 |
2002-01-23 |
Biotech Res Ventures Pte Ltd |
Materials and methods relating to the stabilization and activation of a tumour suppressor protein
|
|
EP1496928A4
(en)
*
|
2002-04-08 |
2005-08-10 |
Ciphergen Biosystems Inc |
SERUM BIOMARKERS IN HEPATOCELLULAR CARCINOMA
|
|
DE60329836D1
(de)
*
|
2002-04-29 |
2009-12-10 |
Univ Jefferson |
Humane chronische lymphozytische leukämie im mausmodell durch gezielte expression von tcl1
|
|
EP1530418A4
(en)
*
|
2002-05-31 |
2005-10-12 |
Univ Leland Stanford Junior |
METHOD FOR IDENTIFYING AND INSULATING STEM CELLS AND CANCER STAMPS
|
|
JP2006512908A
(ja)
*
|
2002-10-11 |
2006-04-20 |
トーマス ジェファーソン ユニバーシティー |
腫瘍抑制遺伝子および組成物ならびにその作製法および使用法
|
|
CA2504605C
(en)
*
|
2002-11-13 |
2016-01-19 |
Thomas Jefferson University |
Treatment of chronic lymphocytic leukemia and prostate cancer with microrna mir15
|
|
US20050069918A1
(en)
*
|
2003-05-29 |
2005-03-31 |
Francois Claret |
JAB1 as a prognostic marker and a therapeutic target for human cancer
|
|
US20050037362A1
(en)
*
|
2003-08-11 |
2005-02-17 |
Eppendorf Array Technologies, S.A. |
Detection and quantification of siRNA on microarrays
|
|
EP1670955A2
(en)
*
|
2003-09-22 |
2006-06-21 |
Rosetta Inpharmatics LLC. |
Synthetic lethal screen using rna interference
|
|
US20070054849A1
(en)
*
|
2003-09-24 |
2007-03-08 |
Oncotherapy Science, Inc. |
Method for diagnosing hepatocellular carcinomas
|
|
US20050186589A1
(en)
*
|
2003-11-07 |
2005-08-25 |
University Of Massachusetts |
Interspersed repetitive element RNAs as substrates, inhibitors and delivery vehicles for RNAi
|
|
EP1713938A2
(en)
*
|
2004-02-09 |
2006-10-25 |
Thomas Jefferson University |
DIAGNOSIS AND TREATMENT OF CANCERS WITH MicroRNA LOCATED IN OR NEAR CANCER-ASSOCIATED CHROMOSOMAL FEATURES
|
|
IL179285A
(en)
*
|
2004-05-14 |
2011-04-28 |
Rosetta Genomics Ltd |
Micrornas and uses thereof
|
|
EP1771563A2
(en)
*
|
2004-05-28 |
2007-04-11 |
Ambion, Inc. |
METHODS AND COMPOSITIONS INVOLVING MicroRNA
|
|
US7635563B2
(en)
*
|
2004-06-30 |
2009-12-22 |
Massachusetts Institute Of Technology |
High throughput methods relating to microRNA expression analysis
|
|
US20060037088A1
(en)
*
|
2004-08-13 |
2006-02-16 |
Shulin Li |
Gene expression levels as predictors of chemoradiation response of cancer
|
|
US7642348B2
(en)
*
|
2004-10-04 |
2010-01-05 |
Rosetta Genomics Ltd |
Prostate cancer-related nucleic acids
|
|
FR2877350B1
(fr)
*
|
2004-11-03 |
2010-08-27 |
Centre Nat Rech Scient |
IDENTIFICATION ET UTILISATION DE miRNAs IMPLIQUES DANS LA DIFFERENCIATION DE CELLULES ISSUES D'UNE LEUCEMIE MYELOIDE
|
|
EP1838852A2
(en)
*
|
2004-11-12 |
2007-10-03 |
Asuragen, Inc. |
Methods and compositions involving mirna and mirna inhibitor molecules
|
|
WO2008073922A2
(en)
*
|
2006-12-08 |
2008-06-19 |
Asuragen, Inc. |
Functions and targets of let-7 micro rnas
|
|
ATE544774T1
(de)
*
|
2004-12-14 |
2012-02-15 |
Alnylam Pharmaceuticals Inc |
Rnai-modulation von mll-af4 und verwendungen dafür
|
|
WO2006069584A2
(en)
*
|
2004-12-29 |
2006-07-06 |
Exiqon A/S |
NOVEL OLIGONUCLEOTIDE COMPOSITIONS AND PROBE SEQUENCES USEFUL FOR DETECTION AND ANALYSIS OF microRNAs AND THEIR TARGET mRNAs
|
|
DE602006016739D1
(de)
*
|
2005-01-25 |
2010-10-21 |
Rosetta Inpharmatics Llc |
Verfahren zur quantifizierung kleiner rna-moleküle
|
|
US20070065840A1
(en)
*
|
2005-03-23 |
2007-03-22 |
Irena Naguibneva |
Novel oligonucleotide compositions and probe sequences useful for detection and analysis of microRNAS and their target mRNAS
|
|
US20070065844A1
(en)
*
|
2005-06-08 |
2007-03-22 |
Massachusetts Institute Of Technology |
Solution-based methods for RNA expression profiling
|
|
US20070123482A1
(en)
*
|
2005-08-10 |
2007-05-31 |
Markus Stoffel |
Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof
|
|
EP2796554A3
(en)
*
|
2005-09-12 |
2014-12-10 |
The Ohio State University Research Foundation |
Compositions for use in treating BCL2-associated cancers
|
|
US7390792B2
(en)
*
|
2005-12-15 |
2008-06-24 |
Board Of Regents, The University Of Texas System |
MicroRNA1 therapies
|
|
CN103361424A
(zh)
*
|
2006-01-05 |
2013-10-23 |
俄亥俄州立大学研究基金会 |
胰腺内分泌和腺泡肿瘤中的微小rna表达异常
|
|
CA2650026C
(en)
*
|
2006-04-24 |
2013-01-22 |
The Ohio State University Research Foundation |
Pre-b cell proliferation and lymphoblastic leukemia/high-grade lymphoma in mir155 transgenic mice
|
|
JP5426383B2
(ja)
*
|
2006-09-19 |
2014-02-26 |
ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション |
慢性リンパ球性白血病におけるmiR−29およびmiR−181によって制御されるTCL1発現
|
|
EP2115138A2
(en)
*
|
2006-09-19 |
2009-11-11 |
Asuragen, Inc. |
Micrornas differentially expressed in pancreatic diseases and uses thereof
|
|
AU2007299804A1
(en)
*
|
2006-09-19 |
2008-03-27 |
Asuragen, Inc. |
MiR-200 regulated genes and pathways as targets for therapeutic intervention
|
|
AU2007299748A1
(en)
*
|
2006-09-19 |
2008-03-27 |
Asuragen, Inc. |
miR-15, miR-26, miR -31,miR -145, miR-147, miR-188, miR-215, miR-216 miR-331, mmu-miR-292-3p regulated genes and pathways as targets for therapeutic intervention
|
|
US8252538B2
(en)
*
|
2006-11-01 |
2012-08-28 |
The Ohio State University |
MicroRNA expression signature for predicting survival and metastases in hepatocellular carcinoma
|
|
US8293684B2
(en)
*
|
2006-11-29 |
2012-10-23 |
Exiqon |
Locked nucleic acid reagents for labelling nucleic acids
|
|
WO2008070082A2
(en)
*
|
2006-12-04 |
2008-06-12 |
The Johns Hopkins University |
Stem-progenitor cell specific micro-ribonucleic acids and uses thereof
|
|
CN101622350A
(zh)
*
|
2006-12-08 |
2010-01-06 |
奥斯瑞根公司 |
作为干预治疗靶标的miR-126调控基因和通路
|
|
AU2007333107A1
(en)
*
|
2006-12-08 |
2008-06-19 |
Asuragen, Inc. |
miR-21 regulated genes and pathways as targets for therapeutic intervention
|
|
WO2008073919A2
(en)
*
|
2006-12-08 |
2008-06-19 |
Asuragen, Inc. |
Mir-20 regulated genes and pathways as targets for therapeutic intervention
|
|
CA2671270A1
(en)
*
|
2006-12-29 |
2008-07-17 |
Asuragen, Inc. |
Mir-16 regulated genes and pathways as targets for therapeutic intervention
|
|
WO2008094545A2
(en)
*
|
2007-01-31 |
2008-08-07 |
The Ohio State University Research Foundation |
Mic orna-based methods and compositions for the treatment of acute myeloid leukemia
|
|
US20100144850A1
(en)
*
|
2007-04-30 |
2010-06-10 |
The Ohio State University Research Foundation |
Methods for Differentiating Pancreatic Cancer from Normal Pancreatic Function and/or Chronic Pancreatitis
|
|
US20090005336A1
(en)
*
|
2007-05-08 |
2009-01-01 |
Zhiguo Wang |
Use of the microRNA miR-1 for the treatment, prevention, and diagnosis of cardiac conditions
|
|
US20090131354A1
(en)
*
|
2007-05-22 |
2009-05-21 |
Bader Andreas G |
miR-126 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION
|
|
US20090099034A1
(en)
*
|
2007-06-07 |
2009-04-16 |
Wisconsin Alumni Research Foundation |
Reagents and Methods for miRNA Expression Analysis and Identification of Cancer Biomarkers
|
|
CA2690749A1
(en)
*
|
2007-06-15 |
2008-12-24 |
The Ohio State University Research Foundation |
Oncogenic all-1 fusion proteins for targeting drosha-mediated microrna processing
|
|
EP2650383A1
(en)
*
|
2007-08-03 |
2013-10-16 |
The Ohio State University Research Foundation |
Ultraconserved regions encoding ncRNAs
|
|
US20090061424A1
(en)
*
|
2007-08-30 |
2009-03-05 |
Sigma-Aldrich Company |
Universal ligation array for analyzing gene expression or genomic variations
|
|
US20090123933A1
(en)
*
|
2007-11-12 |
2009-05-14 |
Wake Forest University Health Sciences |
Microrna biomarkers in lupus
|
|
WO2009070805A2
(en)
*
|
2007-12-01 |
2009-06-04 |
Asuragen, Inc. |
Mir-124 regulated genes and pathways as targets for therapeutic intervention
|
|
US20090192114A1
(en)
*
|
2007-12-21 |
2009-07-30 |
Dmitriy Ovcharenko |
miR-10 Regulated Genes and Pathways as Targets for Therapeutic Intervention
|