JP2009505633A5 - - Google Patents
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- Publication number
- JP2009505633A5 JP2009505633A5 JP2008503299A JP2008503299A JP2009505633A5 JP 2009505633 A5 JP2009505633 A5 JP 2009505633A5 JP 2008503299 A JP2008503299 A JP 2008503299A JP 2008503299 A JP2008503299 A JP 2008503299A JP 2009505633 A5 JP2009505633 A5 JP 2009505633A5
- Authority
- JP
- Japan
- Prior art keywords
- kntc2
- seq
- cdca1
- double
- stranded molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101001112162 Homo sapiens Kinetochore protein NDC80 homolog Proteins 0.000 claims 20
- 102100023890 Kinetochore protein NDC80 homolog Human genes 0.000 claims 19
- 101000590482 Homo sapiens Kinetochore protein Nuf2 Proteins 0.000 claims 15
- 102100032431 Kinetochore protein Nuf2 Human genes 0.000 claims 15
- 239000002773 nucleotide Substances 0.000 claims 15
- 125000003729 nucleotide group Chemical group 0.000 claims 15
- 108091081021 Sense strand Proteins 0.000 claims 10
- 229920001184 polypeptide Polymers 0.000 claims 10
- 102000004196 processed proteins & peptides Human genes 0.000 claims 10
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 9
- 230000000692 anti-sense effect Effects 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 6
- 108091034117 Oligonucleotide Proteins 0.000 claims 5
- 230000014509 gene expression Effects 0.000 claims 5
- 108091028664 Ribonucleotide Proteins 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 239000002336 ribonucleotide Substances 0.000 claims 4
- 125000002652 ribonucleotide group Chemical group 0.000 claims 4
- 239000003153 chemical reaction reagent Substances 0.000 claims 3
- 230000000295 complement effect Effects 0.000 claims 3
- 238000004393 prognosis Methods 0.000 claims 3
- 108020004459 Small interfering RNA Proteins 0.000 claims 2
- 230000004071 biological effect Effects 0.000 claims 2
- 108020004999 messenger RNA Proteins 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 238000010837 poor prognosis Methods 0.000 claims 1
- 108700026220 vif Genes Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70370405P | 2005-07-29 | 2005-07-29 | |
| US60/703,704 | 2005-07-29 | ||
| PCT/JP2006/314715 WO2007013480A2 (en) | 2005-07-29 | 2006-07-19 | Screening and therapeutic method for nsclc targeting cdca1-kntc2 complex |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009505633A JP2009505633A (ja) | 2009-02-12 |
| JP2009505633A5 true JP2009505633A5 (https=) | 2009-09-10 |
| JP5150855B2 JP5150855B2 (ja) | 2013-02-27 |
Family
ID=37434044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008503299A Expired - Fee Related JP5150855B2 (ja) | 2005-07-29 | 2006-07-19 | Cdca1−kntc2複合体を標的とするスクリーニングおよびnsclcの治療方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7943295B2 (https=) |
| EP (1) | EP1915622A2 (https=) |
| JP (1) | JP5150855B2 (https=) |
| CN (1) | CN101283279A (https=) |
| WO (1) | WO2007013480A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100184047A1 (en) * | 2007-03-30 | 2010-07-22 | Oncotherapy Science, Inc. | Screening and therapeutic method for nsclc targeting the cdca8-aurkb complex |
| PT2186889E (pt) * | 2007-08-20 | 2015-06-17 | Oncotherapy Science Inc | Péptido cdca1 e agente farmacêutico que o compreende |
| GB0719367D0 (en) | 2007-10-03 | 2007-11-14 | Procarta Biosystems Ltd | Transcription factor decoys, compositions and methods |
| TWI526219B (zh) * | 2008-06-19 | 2016-03-21 | 腫瘤療法 科學股份有限公司 | Cdca1抗原決定位胜肽及含此胜肽的疫苗 |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| GB201002413D0 (en) | 2010-02-12 | 2010-03-31 | Procarta Biosystems Ltd | Nucleic acid complexes |
| GB201005545D0 (en) | 2010-04-01 | 2010-05-19 | Procarta Biosystems Ltd | Transcription factor decoys |
| EP2872532A4 (en) | 2012-07-10 | 2016-04-13 | Oncotherapy Science Inc | CDCA1-EPITOPPEPTIDES FOR TH1 CELLS AND VACCINES THEREWITH |
| TWI658049B (zh) | 2013-03-12 | 2019-05-01 | 腫瘤療法 科學股份有限公司 | Kntc2胜肽及含此胜肽之疫苗 |
| JP6700512B2 (ja) | 2014-08-04 | 2020-05-27 | オンコセラピー・サイエンス株式会社 | Cdca1由来ペプチドおよびそれを含むワクチン |
| TW202023581A (zh) | 2018-08-02 | 2020-07-01 | 日商腫瘤療法 科學股份有限公司 | 來自cdca1的胜肽及含有此的疫苗 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004500029A (ja) * | 1999-06-30 | 2004-01-08 | コリクサ コーポレイション | 肺癌の治療および診断のための組成物および方法 |
| US20020172952A1 (en) * | 1999-06-30 | 2002-11-21 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
| US20030211510A1 (en) * | 1999-06-30 | 2003-11-13 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
| WO2002004514A2 (en) * | 2000-07-11 | 2002-01-17 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
| WO2003077875A2 (en) * | 2002-03-15 | 2003-09-25 | Incyte Corporation | Proteins associated with growth, differentiation, and death |
| DE60327786D1 (de) | 2002-09-12 | 2009-07-09 | Oncotherapy Science Inc | Kdr-peptide und diese enthaltende impfstoffe |
| US20060024692A1 (en) * | 2002-09-30 | 2006-02-02 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancers |
| AU2003295328A1 (en) * | 2002-10-02 | 2004-04-23 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| GB0306085D0 (en) * | 2002-12-04 | 2003-04-23 | Unilever Plc | Improved composition for topical application |
| AU2003300680A1 (en) | 2002-12-10 | 2004-07-09 | Centre National De La Recherche Scientifique Cnrs | Thap proteins as nuclear receptors for chemokines and roles in transcriptional regulation, cell proliferation and cell differentiation |
| WO2004065577A2 (en) * | 2003-01-14 | 2004-08-05 | Bristol-Myers Squibb Company | Polynucleotides and polypeptides associated with the nf-kb pathway |
| JP2006523456A (ja) | 2003-04-15 | 2006-10-19 | アバロン ファーマシューティカルズ,インコーポレイテッド | 分子細胞遺伝学的方法を用いる癌連鎖遺伝子および治療標的の確認 |
| US7339051B2 (en) * | 2003-04-28 | 2008-03-04 | Isis Pharmaceuticals, Inc. | Compositions and methods for the treatment of severe acute respiratory syndrome (SARS) |
| WO2005019258A2 (en) * | 2003-08-11 | 2005-03-03 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| EP2520652B1 (en) * | 2004-04-09 | 2015-06-10 | Genecare Research Institute Co., Ltd | Cancer cell-specific apoptosis-inducing agents that target chromosome stabilization-associates genes |
| AU2006234897A1 (en) * | 2005-03-16 | 2006-10-19 | Sidney Kimmel Cancer Center | Methods and compositions for predicting death from cancer and prostate cancer survival using gene expression signatures |
| PT2186889E (pt) | 2007-08-20 | 2015-06-17 | Oncotherapy Science Inc | Péptido cdca1 e agente farmacêutico que o compreende |
-
2006
- 2006-07-19 EP EP06781627A patent/EP1915622A2/en not_active Withdrawn
- 2006-07-19 CN CNA200680035270XA patent/CN101283279A/zh active Pending
- 2006-07-19 JP JP2008503299A patent/JP5150855B2/ja not_active Expired - Fee Related
- 2006-07-19 US US11/913,142 patent/US7943295B2/en not_active Expired - Fee Related
- 2006-07-19 WO PCT/JP2006/314715 patent/WO2007013480A2/en not_active Ceased
-
2011
- 2011-04-05 US US13/080,461 patent/US20110263012A1/en not_active Abandoned
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