JP5150855B2 - Cdca1−kntc2複合体を標的とするスクリーニングおよびnsclcの治療方法 - Google Patents

Cdca1−kntc2複合体を標的とするスクリーニングおよびnsclcの治療方法 Download PDF

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JP5150855B2
JP5150855B2 JP2008503299A JP2008503299A JP5150855B2 JP 5150855 B2 JP5150855 B2 JP 5150855B2 JP 2008503299 A JP2008503299 A JP 2008503299A JP 2008503299 A JP2008503299 A JP 2008503299A JP 5150855 B2 JP5150855 B2 JP 5150855B2
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cdca1
kntc2
seq
protein
nsclc
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JP2009505633A (ja
JP2009505633A5 (https=
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祐輔 中村
弥太郎 醍醐
修一 中鶴
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Oncotherapy Science Inc
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Oncotherapy Science Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

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  • Health & Medical Sciences (AREA)
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  • Molecular Biology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
JP2008503299A 2005-07-29 2006-07-19 Cdca1−kntc2複合体を標的とするスクリーニングおよびnsclcの治療方法 Expired - Fee Related JP5150855B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70370405P 2005-07-29 2005-07-29
US60/703,704 2005-07-29
PCT/JP2006/314715 WO2007013480A2 (en) 2005-07-29 2006-07-19 Screening and therapeutic method for nsclc targeting cdca1-kntc2 complex

Publications (3)

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JP2009505633A JP2009505633A (ja) 2009-02-12
JP2009505633A5 JP2009505633A5 (https=) 2009-09-10
JP5150855B2 true JP5150855B2 (ja) 2013-02-27

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JP2008503299A Expired - Fee Related JP5150855B2 (ja) 2005-07-29 2006-07-19 Cdca1−kntc2複合体を標的とするスクリーニングおよびnsclcの治療方法

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US (2) US7943295B2 (https=)
EP (1) EP1915622A2 (https=)
JP (1) JP5150855B2 (https=)
CN (1) CN101283279A (https=)
WO (1) WO2007013480A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100184047A1 (en) * 2007-03-30 2010-07-22 Oncotherapy Science, Inc. Screening and therapeutic method for nsclc targeting the cdca8-aurkb complex
PT2186889E (pt) * 2007-08-20 2015-06-17 Oncotherapy Science Inc Péptido cdca1 e agente farmacêutico que o compreende
GB0719367D0 (en) 2007-10-03 2007-11-14 Procarta Biosystems Ltd Transcription factor decoys, compositions and methods
TWI526219B (zh) * 2008-06-19 2016-03-21 腫瘤療法 科學股份有限公司 Cdca1抗原決定位胜肽及含此胜肽的疫苗
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
GB201002413D0 (en) 2010-02-12 2010-03-31 Procarta Biosystems Ltd Nucleic acid complexes
GB201005545D0 (en) 2010-04-01 2010-05-19 Procarta Biosystems Ltd Transcription factor decoys
EP2872532A4 (en) 2012-07-10 2016-04-13 Oncotherapy Science Inc CDCA1-EPITOPPEPTIDES FOR TH1 CELLS AND VACCINES THEREWITH
TWI658049B (zh) 2013-03-12 2019-05-01 腫瘤療法 科學股份有限公司 Kntc2胜肽及含此胜肽之疫苗
JP6700512B2 (ja) 2014-08-04 2020-05-27 オンコセラピー・サイエンス株式会社 Cdca1由来ペプチドおよびそれを含むワクチン
TW202023581A (zh) 2018-08-02 2020-07-01 日商腫瘤療法 科學股份有限公司 來自cdca1的胜肽及含有此的疫苗

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004500029A (ja) * 1999-06-30 2004-01-08 コリクサ コーポレイション 肺癌の治療および診断のための組成物および方法
US20020172952A1 (en) * 1999-06-30 2002-11-21 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US20030211510A1 (en) * 1999-06-30 2003-11-13 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
WO2002004514A2 (en) * 2000-07-11 2002-01-17 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
WO2003077875A2 (en) * 2002-03-15 2003-09-25 Incyte Corporation Proteins associated with growth, differentiation, and death
DE60327786D1 (de) 2002-09-12 2009-07-09 Oncotherapy Science Inc Kdr-peptide und diese enthaltende impfstoffe
US20060024692A1 (en) * 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
AU2003295328A1 (en) * 2002-10-02 2004-04-23 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
GB0306085D0 (en) * 2002-12-04 2003-04-23 Unilever Plc Improved composition for topical application
AU2003300680A1 (en) 2002-12-10 2004-07-09 Centre National De La Recherche Scientifique Cnrs Thap proteins as nuclear receptors for chemokines and roles in transcriptional regulation, cell proliferation and cell differentiation
WO2004065577A2 (en) * 2003-01-14 2004-08-05 Bristol-Myers Squibb Company Polynucleotides and polypeptides associated with the nf-kb pathway
JP2006523456A (ja) 2003-04-15 2006-10-19 アバロン ファーマシューティカルズ,インコーポレイテッド 分子細胞遺伝学的方法を用いる癌連鎖遺伝子および治療標的の確認
US7339051B2 (en) * 2003-04-28 2008-03-04 Isis Pharmaceuticals, Inc. Compositions and methods for the treatment of severe acute respiratory syndrome (SARS)
WO2005019258A2 (en) * 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
EP2520652B1 (en) * 2004-04-09 2015-06-10 Genecare Research Institute Co., Ltd Cancer cell-specific apoptosis-inducing agents that target chromosome stabilization-associates genes
AU2006234897A1 (en) * 2005-03-16 2006-10-19 Sidney Kimmel Cancer Center Methods and compositions for predicting death from cancer and prostate cancer survival using gene expression signatures
PT2186889E (pt) 2007-08-20 2015-06-17 Oncotherapy Science Inc Péptido cdca1 e agente farmacêutico que o compreende

Also Published As

Publication number Publication date
WO2007013480A3 (en) 2007-06-28
JP2009505633A (ja) 2009-02-12
WO2007013480A2 (en) 2007-02-01
EP1915622A2 (en) 2008-04-30
US20090215683A1 (en) 2009-08-27
US7943295B2 (en) 2011-05-17
US20110263012A1 (en) 2011-10-27
CN101283279A (zh) 2008-10-08

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