JP2006500948A5 - - Google Patents
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- Publication number
- JP2006500948A5 JP2006500948A5 JP2004541226A JP2004541226A JP2006500948A5 JP 2006500948 A5 JP2006500948 A5 JP 2006500948A5 JP 2004541226 A JP2004541226 A JP 2004541226A JP 2004541226 A JP2004541226 A JP 2004541226A JP 2006500948 A5 JP2006500948 A5 JP 2006500948A5
- Authority
- JP
- Japan
- Prior art keywords
- pnc
- compound
- pancreatic cancer
- treating
- detecting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 15
- 150000001875 compounds Chemical class 0.000 claims 14
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 7
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 7
- 201000002528 pancreatic cancer Diseases 0.000 claims 7
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 7
- 210000004027 cell Anatomy 0.000 claims 5
- 230000004071 biological effect Effects 0.000 claims 4
- 239000012472 biological sample Substances 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 238000012216 screening Methods 0.000 claims 4
- 108700008625 Reporter Genes Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical group 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 210000002919 epithelial cell Anatomy 0.000 claims 2
- 201000008129 pancreatic ductal adenocarcinoma Diseases 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 230000001105 regulatory effect Effects 0.000 claims 2
- 230000002103 transcriptional effect Effects 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 1
- 108020004459 Small interfering RNA Proteins 0.000 claims 1
- 230000000692 anti-sense effect Effects 0.000 claims 1
- 230000027455 binding Effects 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 239000004055 small Interfering RNA Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41487202P | 2002-09-30 | 2002-09-30 | |
| US45088903P | 2003-02-28 | 2003-02-28 | |
| PCT/JP2003/011817 WO2004031412A2 (en) | 2002-09-30 | 2003-09-17 | Method for diagnosing pancreatic cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006500948A JP2006500948A (ja) | 2006-01-12 |
| JP2006500948A5 true JP2006500948A5 (https=) | 2006-11-02 |
Family
ID=32073343
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004541224A Expired - Fee Related JP4679149B2 (ja) | 2002-09-30 | 2003-09-12 | ヒト膵癌に関連する遺伝子およびポリペプチド |
| JP2004541226A Pending JP2006500948A (ja) | 2002-09-30 | 2003-09-17 | 膵臓癌を診断する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004541224A Expired - Fee Related JP4679149B2 (ja) | 2002-09-30 | 2003-09-12 | ヒト膵癌に関連する遺伝子およびポリペプチド |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US7601826B2 (https=) |
| EP (3) | EP1556518B1 (https=) |
| JP (2) | JP4679149B2 (https=) |
| CN (1) | CN1703524B (https=) |
| AT (2) | ATE419391T1 (https=) |
| AU (2) | AU2003260966A1 (https=) |
| CA (2) | CA2500472A1 (https=) |
| DE (2) | DE60325628D1 (https=) |
| ES (1) | ES2320443T3 (https=) |
| WO (2) | WO2004031411A2 (https=) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060024692A1 (en) * | 2002-09-30 | 2006-02-02 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancers |
| US7217807B2 (en) | 2002-11-26 | 2007-05-15 | Rosetta Genomics Ltd | Bioinformatically detectable group of novel HIV regulatory genes and uses thereof |
| US7888497B2 (en) | 2003-08-13 | 2011-02-15 | Rosetta Genomics Ltd. | Bioinformatically detectable group of novel regulatory oligonucleotides and uses thereof |
| TW200538739A (en) * | 2004-02-27 | 2005-12-01 | Oncotherapy Science Inc | EphA4 as therapeutic target of PRC and PDACa |
| US7939251B2 (en) * | 2004-05-06 | 2011-05-10 | Roche Molecular Systems, Inc. | SENP1 as a marker for cancer |
| JP5697297B2 (ja) | 2004-05-14 | 2015-04-08 | ロゼッタ ジノミクス リミテッド | マイクロｎａｓおよびその使用 |
| US7687616B1 (en) | 2004-05-14 | 2010-03-30 | Rosetta Genomics Ltd | Small molecules modulating activity of micro RNA oligonucleotides and micro RNA targets and uses thereof |
| CA2567350C (en) * | 2004-05-21 | 2018-06-12 | John D. Shaughnessy | Use of gene expression profiling to predict survival in cancer patient |
| US7795419B2 (en) | 2004-05-26 | 2010-09-14 | Rosetta Genomics Ltd. | Viral and viral associated miRNAs and uses thereof |
| WO2006038904A2 (en) * | 2004-08-06 | 2006-04-13 | Applera Corporation | Method and compositions for treating diseases targeting e-cadherin |
| DE102004042822A1 (de) * | 2004-08-31 | 2006-03-16 | Technische Universität Dresden | Verbindungen und Methoden zur Behandlung, Diagnose und Prognose bei Pankreaserkrankungen |
| DE102004049897B4 (de) * | 2004-10-13 | 2007-11-22 | Sirs-Lab Gmbh | Verfahren zur Unterscheidung zwischen nichtinfektiösen und infektiösen Ursachen eines Multiorganversagens |
| EP1917274A2 (en) * | 2005-07-28 | 2008-05-07 | Oncotherapy Science, Inc. | Vivit polypeptides, therapeutic agent comprising the same, and method of screening for anti-cancer agent |
| EP2402758B1 (en) | 2005-09-19 | 2014-09-10 | Janssen Diagnostics, LLC | Methods and uses for identifying the origin of a carcinoma of unknown primary origin |
| US8138167B2 (en) | 2006-02-10 | 2012-03-20 | Oncotherapy Science, Inc. | Methods for treating lung cancers |
| US8003098B2 (en) | 2006-02-28 | 2011-08-23 | Oncotherapy Science, Inc. | Methods for damaging cells using effector functions of anti-EphA4 antibodies |
| CA2645125A1 (en) * | 2006-03-02 | 2007-09-13 | Oncotherapy Science, Inc. | Methods for diagnosing pancreatic cancer using reg4 protein |
| CN1904072B (zh) * | 2006-07-28 | 2012-07-18 | 浙江大学 | 一组筛选胰腺导管腺癌的基因组合及应用 |
| RU2009109692A (ru) * | 2006-08-18 | 2010-09-27 | Онкотерапи Сайенс, Инк. (Jp) | Лечение или предотвращение развития злокачественных опухолей, сверхэкспрессирующих reg4 или kiaa0101 |
| US7811778B2 (en) * | 2006-09-06 | 2010-10-12 | Vanderbilt University | Methods of screening for gastrointestinal cancer |
| WO2008117067A2 (en) | 2007-03-27 | 2008-10-02 | Carl Arne Krister Borrebaeck | Protein signature/markers for the detection of adenocarcinoma |
| CN101827936B (zh) * | 2007-08-20 | 2014-12-10 | 肿瘤疗法科学股份有限公司 | Cdh3肽以及含有cdh3肽的药剂 |
| US8569244B2 (en) | 2007-08-20 | 2013-10-29 | Oncotherapy Science, Inc. | FOXM1 peptide and medicinal agent comprising the same |
| US8435749B2 (en) | 2008-06-30 | 2013-05-07 | Oncotherapy Science, Inc. | Anti-CDH3 antibodies labeled with radioisotope label and uses thereof |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| BRPI0918844A2 (pt) * | 2008-08-27 | 2015-12-08 | Oncotherapy Science Inc | syngr4 para genes-alvo de terapia e diagnóstico do câncer |
| US10359425B2 (en) | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| US20100135991A1 (en) * | 2008-11-17 | 2010-06-03 | Chiu-Chen Huang | Antibodies recognizing oxygen-regulated protein 150 expressed on cancer cells and methods of using same |
| TWI469791B (zh) * | 2009-02-18 | 2015-01-21 | Oncotherapy Science Inc | Ｆｏｘｍ１胜肽以及含此胜肽之疫苗 |
| DE102010043541B4 (de) * | 2009-12-16 | 2012-01-26 | Technische Universität Dresden | Verfahren und Mittel zur Vorhersage der Überlebensdauer beim Pankreaskarzinom durch Analyse von Biomarkern |
| US9017669B2 (en) | 2009-12-28 | 2015-04-28 | Oncotherapy Science, Inc. | Anti-CDH3 antibodies and uses thereof |
| JP2013518560A (ja) * | 2010-02-03 | 2013-05-23 | オンコセラピー・サイエンス株式会社 | がんの治療および診断の標的遺伝子としてのｗｈｓｃ１およびｗｈｓｃ１ｌ１ |
| AU2011260390B2 (en) * | 2010-06-01 | 2016-11-24 | Ernst-Moritz-Arndt Universitat Greifswald | Means and methods for diagnosing pancreatic cancer in a subject |
| SG186953A1 (en) | 2010-07-09 | 2013-02-28 | Somalogic Inc | Lung cancer biomarkers and uses thereof |
| CN103415624B (zh) * | 2010-08-13 | 2017-03-01 | 私募蛋白质体公司 | 胰腺癌生物标记及其用途 |
| EP2625292B1 (en) | 2010-10-07 | 2018-12-05 | The General Hospital Corporation | Biomarkers of cancer |
| KR101297336B1 (ko) | 2011-03-30 | 2013-08-14 | 인하대학교 산학협력단 | 점액성 낭성종양 진단 장치 |
| KR101223598B1 (ko) | 2011-04-06 | 2013-01-22 | 인하대학교 산학협력단 | 췌장 상피내 종양 진단 시스템 |
| JP6247218B2 (ja) * | 2011-10-24 | 2017-12-13 | ザ ジェネラル ホスピタル コーポレイション | 癌のバイオマーカー |
| WO2014189843A1 (en) | 2013-05-20 | 2014-11-27 | Board Of Trustees Of The University Of Arkansas | Gep5 model for multiple myeloma |
| GB201319878D0 (en) * | 2013-11-11 | 2013-12-25 | Immunovia Ab | Method, Array and use thereof |
| BR112016020897A2 (en) * | 2014-03-11 | 2018-01-23 | The Council Of The Queensland Institute Of Medical Research | Determination of cancer aggressiveness, prognosis, and responsiveness to treatment |
| US10451628B2 (en) * | 2014-05-07 | 2019-10-22 | University Of Utah Research Foundation | Biomarkers and methods for diagnosis of early stage pancreatic ductal adenocarcinoma |
| EP3161159B1 (en) | 2014-06-25 | 2020-08-05 | The General Hospital Corporation | Targeting human satellite ii (hsatii) |
| CA2962476C (en) | 2014-09-26 | 2023-09-26 | Hi-Stem Ggmbh | Novel methods for sub-typing and treating cancer |
| GB201501930D0 (en) | 2015-02-05 | 2015-03-25 | Univ London Queen Mary | Biomarkers for pancreatic cancer |
| JP2018136122A (ja) * | 2015-05-29 | 2018-08-30 | 国立研究開発法人国立がん研究センター | 膵がんを診断するための血漿バイオマーカーパネル |
| CN105017403B (zh) * | 2015-07-09 | 2018-07-03 | 陈勇 | 胰腺癌相关多肽dap44单克隆抗体的制备及其应用 |
| BR112018005581A2 (pt) | 2015-10-08 | 2018-10-16 | Oncotherapy Science, Inc. | peptídeo derivado de foxm1 e vacina incluindo o mesmo |
| US11203615B2 (en) * | 2017-09-11 | 2021-12-21 | National University Corporation Hokkaido University | Cancer treatment drug |
| EP3508855A1 (en) * | 2018-01-05 | 2019-07-10 | Allianz Pharmascience Ltd | Method for the selection of patients and kit |
| US12582702B2 (en) * | 2018-05-11 | 2026-03-24 | University Of Massachusetts | Methods for improving leptin sensitivity for the treatment of obesity and diabetes |
| KR102328654B1 (ko) * | 2019-04-17 | 2021-11-19 | 한국원자력의학원 | 암의 예방 또는 치료용 약학 조성물 |
| KR102289278B1 (ko) * | 2019-07-09 | 2021-08-13 | 주식회사 베르티스 | 췌장암 진단용 바이오마커 패널 및 그 용도 |
| IL299826A (en) | 2020-07-15 | 2023-03-01 | Cerebral Therapeutics Inc | A medical device with a non-filtered CSF withdrawal path |
| GB202010970D0 (en) | 2020-07-16 | 2020-09-02 | Immunovia Ab | Methods, arrays and uses thereof |
| US12605537B2 (en) | 2022-02-15 | 2026-04-21 | Biogen Ma Inc. | Implantable medical device for use with or having recording electrode |
| CN115074365B (zh) * | 2022-06-28 | 2023-02-28 | 中国医学科学院北京协和医院 | 靶向GATM基因的sgRNA及其应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US6333152B1 (en) | 1997-05-21 | 2001-12-25 | The Johnshopkins University | Gene expression profiles in normal and cancer cells |
| EP1038030A2 (en) * | 1997-12-15 | 2000-09-27 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the pancreas |
| US6262249B1 (en) * | 1998-06-23 | 2001-07-17 | Chiron Corporation | Pancreatic cancer genes |
| WO2001064835A2 (en) * | 2000-02-28 | 2001-09-07 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| US20020119158A1 (en) * | 1998-12-17 | 2002-08-29 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
| US6429302B1 (en) * | 1999-02-02 | 2002-08-06 | Chiron Corporation | Polynucleotides related to pancreatic disease |
| AU3395900A (en) | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| WO2001009318A1 (fr) | 1999-07-29 | 2001-02-08 | Helix Research Institute | Genes associes au cancer du foie |
| CA2491433A1 (en) | 1999-12-01 | 2001-06-07 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WO2001055301A2 (en) | 2000-01-31 | 2001-08-02 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| CA2411601A1 (en) * | 2000-06-05 | 2001-12-13 | Avalon Pharmaceuticals | Cancer gene determination and therapeutic screening using signature gene sets |
| US6974667B2 (en) | 2000-06-14 | 2005-12-13 | Gene Logic, Inc. | Gene expression profiles in liver cancer |
| AU2002255478A1 (en) | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
| AU2002366951A1 (en) * | 2001-12-10 | 2003-07-09 | Nuvelo,Inc. | Novel nucleic acids and polypeptides |
| US20060024692A1 (en) * | 2002-09-30 | 2006-02-02 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancers |
| US20050260639A1 (en) * | 2002-09-30 | 2005-11-24 | Oncotherapy Science, Inc. | Method for diagnosing pancreatic cancer |
| CA2500982A1 (en) | 2002-09-30 | 2004-04-15 | Oncotherapy Science, Inc. | Method for diagnosing testicular seminomas |
| CA2645125A1 (en) * | 2006-03-02 | 2007-09-13 | Oncotherapy Science, Inc. | Methods for diagnosing pancreatic cancer using reg4 protein |
-
2003
- 2003-09-12 JP JP2004541224A patent/JP4679149B2/ja not_active Expired - Fee Related
- 2003-09-12 CN CN038255073A patent/CN1703524B/zh not_active Expired - Fee Related
- 2003-09-12 AT AT03799104T patent/ATE419391T1/de not_active IP Right Cessation
- 2003-09-12 ES ES03799104T patent/ES2320443T3/es not_active Expired - Lifetime
- 2003-09-12 CA CA002500472A patent/CA2500472A1/en not_active Abandoned
- 2003-09-12 DE DE60325628T patent/DE60325628D1/de not_active Expired - Lifetime
- 2003-09-12 AU AU2003260966A patent/AU2003260966A1/en not_active Abandoned
- 2003-09-12 WO PCT/JP2003/011713 patent/WO2004031411A2/en not_active Ceased
- 2003-09-12 US US10/529,592 patent/US7601826B2/en not_active Expired - Fee Related
- 2003-09-12 EP EP03799104A patent/EP1556518B1/en not_active Expired - Lifetime
- 2003-09-17 JP JP2004541226A patent/JP2006500948A/ja active Pending
- 2003-09-17 DE DE60325617T patent/DE60325617D1/de not_active Expired - Fee Related
- 2003-09-17 EP EP08014535A patent/EP2009117A3/en not_active Withdrawn
- 2003-09-17 WO PCT/JP2003/011817 patent/WO2004031412A2/en not_active Ceased
- 2003-09-17 EP EP03799106A patent/EP1549771B1/en not_active Expired - Lifetime
- 2003-09-17 AT AT03799106T patent/ATE419390T1/de not_active IP Right Cessation
- 2003-09-17 CA CA002500482A patent/CA2500482A1/en not_active Abandoned
- 2003-09-17 AU AU2003263603A patent/AU2003263603A1/en not_active Abandoned
-
2009
- 2009-08-31 US US12/551,372 patent/US7943730B2/en not_active Expired - Fee Related
-
2011
- 2011-04-04 US US13/079,274 patent/US20120028262A1/en not_active Abandoned
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