JP2009502807A - 薬剤含有率の高い製剤および投与量形態 - Google Patents

薬剤含有率の高い製剤および投与量形態 Download PDF

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JP2009502807A
JP2009502807A JP2008523032A JP2008523032A JP2009502807A JP 2009502807 A JP2009502807 A JP 2009502807A JP 2008523032 A JP2008523032 A JP 2008523032A JP 2008523032 A JP2008523032 A JP 2008523032A JP 2009502807 A JP2009502807 A JP 2009502807A
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biphenylyl
fluoro
propionic acid
dosage form
unit dosage
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JP2009502807A5 (enExample
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ゲイレン エム． ゼントナー，
ジェームス シー． マクリー，
マーク エス． ウィリアムス，
グレゴリー ティー． エートマン，
トレーシー アネット パワーズ，
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ミリアド ジェネティクス， インコーポレイテッド
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Publication of JP2009502807A5 publication Critical patent/JP2009502807A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2008523032A 2005-07-22 2006-07-24 薬剤含有率の高い製剤および投与量形態 Withdrawn JP2009502807A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70171005P 2005-07-22 2005-07-22
US70634405P 2005-08-08 2005-08-08
PCT/US2006/028602 WO2007014124A2 (en) 2005-07-22 2006-07-24 High drug load formulations and dosage forms

Publications (2)

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JP2009502807A true JP2009502807A (ja) 2009-01-29
JP2009502807A5 JP2009502807A5 (enExample) 2009-08-27

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JP2008523032A Withdrawn JP2009502807A (ja) 2005-07-22 2006-07-24 薬剤含有率の高い製剤および投与量形態

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Country Link
US (2) US20070042034A1 (enExample)
EP (1) EP1909777A2 (enExample)
JP (1) JP2009502807A (enExample)
KR (1) KR20080039876A (enExample)
AU (1) AU2006272760A1 (enExample)
BR (1) BRPI0613611A2 (enExample)
CA (1) CA2615063A1 (enExample)
EA (1) EA200800360A1 (enExample)
IL (1) IL188744A0 (enExample)
NO (1) NO20080220L (enExample)
NZ (1) NZ564789A (enExample)
WO (1) WO2007014124A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017521469A (ja) * 2014-07-25 2017-08-03 ノバルティス アーゲー ２−フルオロ−ｎ−メチル−４−［７−（キノリン−６−イルメチル）イミダゾ［１，２−ｂ］［１，２，４］トリアジン−２−イル］ベンズアミドの錠剤

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KR101501569B1 (ko) * 2013-01-23 2015-03-11 임익철 치매 예방 및 치료를 위한 수용성 규산염 조성물 및 이의 제조방법
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JP2017521469A (ja) * 2014-07-25 2017-08-03 ノバルティス アーゲー ２−フルオロ−ｎ−メチル−４−［７−（キノリン−６−イルメチル）イミダゾ［１，２−ｂ］［１，２，４］トリアジン−２−イル］ベンズアミドの錠剤
JP2020114852A (ja) * 2014-07-25 2020-07-30 ノバルティス アーゲー ２−フルオロ−ｎ−メチル−４−［７−（キノリン−６−イルメチル）イミダゾ［１，２−ｂ］［１，２，４］トリアジン−２−イル］ベンズアミドの錠剤
JP7002587B2 (ja) 2014-07-25 2022-01-20 ノバルティス アーゲー ２－フルオロ－ｎ－メチル－４－［７－（キノリン－６－イルメチル）イミダゾ［１，２－ｂ］［１，２，４］トリアジン－２－イル］ベンズアミドの錠剤
JP2022046659A (ja) * 2014-07-25 2022-03-23 ノバルティス アーゲー ２－フルオロ－ｎ－メチル－４－［７－（キノリン－６－イルメチル）イミダゾ［１，２－ｂ］［１，２，４］トリアジン－２－イル］ベンズアミドの錠剤

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EA200800360A1 (ru) 2008-06-30
WO2007014124A2 (en) 2007-02-01
EP1909777A2 (en) 2008-04-16
CA2615063A1 (en) 2007-02-01
KR20080039876A (ko) 2008-05-07
US20110111025A1 (en) 2011-05-12
US20070042034A1 (en) 2007-02-22
AU2006272760A1 (en) 2007-02-01
NZ564789A (en) 2010-07-30

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