JP2009501174A - ペルフルオロアルキル含有錯体、製造方法およびその使用 - Google Patents

ペルフルオロアルキル含有錯体、製造方法およびその使用 Download PDF

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Publication number
JP2009501174A
JP2009501174A JP2008520780A JP2008520780A JP2009501174A JP 2009501174 A JP2009501174 A JP 2009501174A JP 2008520780 A JP2008520780 A JP 2008520780A JP 2008520780 A JP2008520780 A JP 2008520780A JP 2009501174 A JP2009501174 A JP 2009501174A
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JP
Japan
Prior art keywords
groups
mmol
group
metal complex
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2008520780A
Other languages
English (en)
Japanese (ja)
Inventor
シルマー ハイコ
ヴァインマン ハンス−ヨアヒム
プラツェク ヨハネス
ツォルン ルートヴィッヒ
ミセルヴィッツ ベルント
メディンク イェルク
シュミット−ヴィリッヒ ヘリベルト
ブルムビイ トーマス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Epix Pharmaceuticals Inc
Original Assignee
Bayer Schering Pharma AG
Epix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma AG, Epix Pharmaceuticals Inc filed Critical Bayer Schering Pharma AG
Publication of JP2009501174A publication Critical patent/JP2009501174A/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2008520780A 2005-07-15 2006-07-11 ペルフルオロアルキル含有錯体、製造方法およびその使用 Withdrawn JP2009501174A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005033902A DE102005033902B3 (de) 2005-07-15 2005-07-15 Perfluoralkylhaltige Komplexe, Verfahren zu deren Herstellung, sowie deren Verwendung und diese enthaltende pharmazeutische Mittel
PCT/EP2006/006777 WO2007009638A2 (de) 2005-07-15 2006-07-11 Perfluoralkylhaltige komplexe, verfahren zu deren herstellung sowie deren verwendung

Publications (1)

Publication Number Publication Date
JP2009501174A true JP2009501174A (ja) 2009-01-15

Family

ID=37057146

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008520780A Withdrawn JP2009501174A (ja) 2005-07-15 2006-07-11 ペルフルオロアルキル含有錯体、製造方法およびその使用

Country Status (22)

Country Link
EP (1) EP1904463A2 (es)
JP (1) JP2009501174A (es)
KR (1) KR20080043762A (es)
CN (1) CN101223148A (es)
AR (1) AR054865A1 (es)
AU (1) AU2006272025A1 (es)
BR (1) BRPI0613407A2 (es)
CA (1) CA2615443A1 (es)
CR (1) CR9645A (es)
DE (1) DE102005033902B3 (es)
DO (1) DOP2006000167A (es)
EC (1) ECSP088100A (es)
GT (1) GT200600313A (es)
IL (1) IL187926A0 (es)
NO (1) NO20080813L (es)
PE (1) PE20070376A1 (es)
RU (1) RU2008105356A (es)
TN (1) TNSN08016A1 (es)
TW (1) TW200706538A (es)
UY (1) UY29664A1 (es)
WO (1) WO2007009638A2 (es)
ZA (1) ZA200801523B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015180623A (ja) * 2008-01-08 2015-10-15 ランセウス メディカル イメージング， インコーポレイテッド 造影剤としてのｎ−アルコキシアミド抱合体

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007015598A1 (de) * 2007-03-29 2008-10-02 Heinrich-Heine-Universität Düsseldorf Verwendung von fluorhaltigen Verbindungen zu Diagnosezwecken mit Hilfe bildgebender Verfahren
US20210101905A1 (en) * 2019-10-04 2021-04-08 Llnited States Government as represented by the Department of Veterans Affairs Development of Imaging and Therapeutic Glucose Analogues for Sodium Dependent Glucose Transporters
EP4059925A1 (en) 2021-03-15 2022-09-21 Bayer Aktiengesellschaft New contrast agent for use in magnetic resonance imaging
CN114181164A (zh) * 2021-12-13 2022-03-15 武汉大学中南医院 基于Fe(Ⅱ)特异性MRI对比剂的合成方法及其应用
EP4335462A1 (en) 2022-09-09 2024-03-13 Bayer AG Contrast agents for use in diagnostic computed tomography imaging
EP4335840A1 (en) 2022-09-09 2024-03-13 Bayer Aktiengesellschaft New contrast agents for use in diagnostic imaging

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4317588C2 (de) * 1993-05-24 1998-04-16 Schering Ag Fluorhaltige makrocyclische Metallkomplexe, Verfahren zu ihrer Herstellung, sowie ihre Verwendung
DE19603033A1 (de) * 1996-01-19 1997-07-24 Schering Ag Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
DE19744004C1 (de) * 1997-09-26 1999-07-22 Schering Ag Lipophile Metall-Komplexe für Nekrose und Infarkt-Imaging
DE19744003B4 (de) * 1997-09-26 2004-07-08 Schering Ag Kontrastmittel für das Infarkt- und Nekroseimaging
DE19914101C1 (de) * 1999-03-22 2000-10-12 Schering Ag Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik
DE10040858C2 (de) * 2000-08-11 2003-12-18 Schering Ag Perfluoralkylhaltige Komplexe mit polaren Resten, Verfahren zu deren Herstellung und ihre Verwendung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015180623A (ja) * 2008-01-08 2015-10-15 ランセウス メディカル イメージング， インコーポレイテッド 造影剤としてのｎ−アルコキシアミド抱合体

Also Published As

Publication number Publication date
CR9645A (es) 2008-05-21
AU2006272025A1 (en) 2007-01-25
DOP2006000167A (es) 2007-02-28
ZA200801523B (en) 2008-11-26
IL187926A0 (en) 2008-03-20
EP1904463A2 (de) 2008-04-02
AR054865A1 (es) 2007-07-25
BRPI0613407A2 (pt) 2011-01-11
WO2007009638A2 (de) 2007-01-25
GT200600313A (es) 2007-04-23
KR20080043762A (ko) 2008-05-19
CN101223148A (zh) 2008-07-16
ECSP088100A (es) 2008-05-30
DE102005033902B3 (de) 2007-04-05
NO20080813L (no) 2008-04-09
WO2007009638A3 (de) 2007-04-26
PE20070376A1 (es) 2007-04-20
RU2008105356A (ru) 2009-08-20
UY29664A1 (es) 2007-02-28
TNSN08016A1 (en) 2009-07-14
TW200706538A (en) 2007-02-16
CA2615443A1 (en) 2007-01-25

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