CN101223148A - 含全氟烷基络合物、其制备方法及其应用 - Google Patents

含全氟烷基络合物、其制备方法及其应用 Download PDF

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Publication number
CN101223148A
CN101223148A CNA2006800258905A CN200680025890A CN101223148A CN 101223148 A CN101223148 A CN 101223148A CN A2006800258905 A CNA2006800258905 A CN A2006800258905A CN 200680025890 A CN200680025890 A CN 200680025890A CN 101223148 A CN101223148 A CN 101223148A
Authority
CN
China
Prior art keywords
group
metal complex
general formula
implication
och
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006800258905A
Other languages
English (en)
Chinese (zh)
Inventor
H·席尔默
H-J·魏因曼
J·普拉策克
L·措恩
B·米塞尔维茨
J·梅丁
H·施米特-维利希
T·布伦比
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Epix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG, Epix Pharmaceuticals Inc filed Critical Schering AG
Publication of CN101223148A publication Critical patent/CN101223148A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CNA2006800258905A 2005-07-15 2006-07-11 含全氟烷基络合物、其制备方法及其应用 Pending CN101223148A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005033902.6 2005-07-15
DE102005033902A DE102005033902B3 (de) 2005-07-15 2005-07-15 Perfluoralkylhaltige Komplexe, Verfahren zu deren Herstellung, sowie deren Verwendung und diese enthaltende pharmazeutische Mittel

Publications (1)

Publication Number Publication Date
CN101223148A true CN101223148A (zh) 2008-07-16

Family

ID=37057146

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2006800258905A Pending CN101223148A (zh) 2005-07-15 2006-07-11 含全氟烷基络合物、其制备方法及其应用

Country Status (22)

Country Link
EP (1) EP1904463A2 (es)
JP (1) JP2009501174A (es)
KR (1) KR20080043762A (es)
CN (1) CN101223148A (es)
AR (1) AR054865A1 (es)
AU (1) AU2006272025A1 (es)
BR (1) BRPI0613407A2 (es)
CA (1) CA2615443A1 (es)
CR (1) CR9645A (es)
DE (1) DE102005033902B3 (es)
DO (1) DOP2006000167A (es)
EC (1) ECSP088100A (es)
GT (1) GT200600313A (es)
IL (1) IL187926A0 (es)
NO (1) NO20080813L (es)
PE (1) PE20070376A1 (es)
RU (1) RU2008105356A (es)
TN (1) TNSN08016A1 (es)
TW (1) TW200706538A (es)
UY (1) UY29664A1 (es)
WO (1) WO2007009638A2 (es)
ZA (1) ZA200801523B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007015598A1 (de) * 2007-03-29 2008-10-02 Heinrich-Heine-Universität Düsseldorf Verwendung von fluorhaltigen Verbindungen zu Diagnosezwecken mit Hilfe bildgebender Verfahren
CA2711426C (en) 2008-01-08 2018-05-22 Lantheus Medical Imaging, Inc. N-alkoxyamide conjugates as imaging agents
CA3153519A1 (en) * 2019-10-04 2021-04-08 Bryan J. Traughber Development of imaging and therapeutic glucose analogues for sodium dependent glucose transporters
EP4059925A1 (en) 2021-03-15 2022-09-21 Bayer Aktiengesellschaft New contrast agent for use in magnetic resonance imaging
CN114181164A (zh) * 2021-12-13 2022-03-15 武汉大学中南医院 基于Fe(Ⅱ)特异性MRI对比剂的合成方法及其应用
EP4335840A1 (en) 2022-09-09 2024-03-13 Bayer Aktiengesellschaft New contrast agents for use in diagnostic imaging
EP4335462A1 (en) 2022-09-09 2024-03-13 Bayer AG Contrast agents for use in diagnostic computed tomography imaging

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4317588C2 (de) * 1993-05-24 1998-04-16 Schering Ag Fluorhaltige makrocyclische Metallkomplexe, Verfahren zu ihrer Herstellung, sowie ihre Verwendung
DE19603033A1 (de) * 1996-01-19 1997-07-24 Schering Ag Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
DE19744004C1 (de) * 1997-09-26 1999-07-22 Schering Ag Lipophile Metall-Komplexe für Nekrose und Infarkt-Imaging
DE19744003B4 (de) * 1997-09-26 2004-07-08 Schering Ag Kontrastmittel für das Infarkt- und Nekroseimaging
DE19914101C1 (de) * 1999-03-22 2000-10-12 Schering Ag Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik
DE10040858C2 (de) * 2000-08-11 2003-12-18 Schering Ag Perfluoralkylhaltige Komplexe mit polaren Resten, Verfahren zu deren Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
ECSP088100A (es) 2008-05-30
EP1904463A2 (de) 2008-04-02
CR9645A (es) 2008-05-21
GT200600313A (es) 2007-04-23
DOP2006000167A (es) 2007-02-28
UY29664A1 (es) 2007-02-28
KR20080043762A (ko) 2008-05-19
PE20070376A1 (es) 2007-04-20
CA2615443A1 (en) 2007-01-25
WO2007009638A2 (de) 2007-01-25
TW200706538A (en) 2007-02-16
NO20080813L (no) 2008-04-09
BRPI0613407A2 (pt) 2011-01-11
WO2007009638A3 (de) 2007-04-26
IL187926A0 (en) 2008-03-20
RU2008105356A (ru) 2009-08-20
AR054865A1 (es) 2007-07-25
DE102005033902B3 (de) 2007-04-05
TNSN08016A1 (en) 2009-07-14
ZA200801523B (en) 2008-11-26
JP2009501174A (ja) 2009-01-15
AU2006272025A1 (en) 2007-01-25

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Effective date of registration: 20081205

Address after: Berlin

Applicant after: Schering AG

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