JP2009500397A

JP2009500397A - エピナスチンを含む眼科用経皮吸収型製剤

エピナスチンを含む眼科用経皮吸収型製剤 Download PDF

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Publication number: JP2009500397A
Authority: JP; Japan
Prior art keywords: epinastine; pharmaceutically acceptable; acceptable salt; subject; hours
Prior art date: 2005-07-08
Legal status : Abandoned

Application number

JP2008520118A

Other languages

English (en)

Japanese (ja)

Other versions

JP2009500397A5 (enExample

Inventor

明治礒脇

朋子中嶋

聡大鳥

Current Assignee

Senju Pharmaceutical Co Ltd

Original Assignee

Senju Pharmaceutical Co Ltd

Priority date

2005-07-08

Filing date

2006-07-07

Publication date

2009-01-08

2006-07-07 Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd

2009-01-08 Publication of JP2009500397A publication Critical patent/JP2009500397A/ja

2009-08-20 Publication of JP2009500397A5 publication Critical patent/JP2009500397A5/ja

Status Abandoned legal-status Critical Current

Links

WHWZLSFABNNENI-UHFFFAOYSA-N epinastine Chemical compound C1C2=CC=CC=C2C2CN=C(N)N2C2=CC=CC=C21 WHWZLSFABNNENI-UHFFFAOYSA-N 0.000 title claims abstract description 107
229960003449 epinastine Drugs 0.000 title claims abstract description 93
238000002360 preparation method Methods 0.000 title claims abstract description 83
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KSCKTBJJRVPGKM-UHFFFAOYSA-N octan-1-olate;titanium(4+) Chemical compound [Ti+4].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-] KSCKTBJJRVPGKM-UHFFFAOYSA-N 0.000 description 1
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RPDAUEIUDPHABB-UHFFFAOYSA-N potassium ethoxide Chemical compound [K+].CC[O-] RPDAUEIUDPHABB-UHFFFAOYSA-N 0.000 description 1
BDAWXSQJJCIFIK-UHFFFAOYSA-N potassium methoxide Chemical compound [K+].[O-]C BDAWXSQJJCIFIK-UHFFFAOYSA-N 0.000 description 1
LPNYRYFBWFDTMA-UHFFFAOYSA-N potassium tert-butoxide Chemical compound [K+].CC(C)(C)[O-] LPNYRYFBWFDTMA-UHFFFAOYSA-N 0.000 description 1
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IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
DCBSHORRWZKAKO-UHFFFAOYSA-N rac-1-monomyristoylglycerol Chemical compound CCCCCCCCCCCCCC(=O)OCC(O)CO DCBSHORRWZKAKO-UHFFFAOYSA-N 0.000 description 1
SJOXEWUZWQYCGL-UHFFFAOYSA-N salicylic acid menthyl ester Natural products CC(C)C1CCC(C)CC1OC(=O)C1=CC=CC=C1O SJOXEWUZWQYCGL-UHFFFAOYSA-N 0.000 description 1
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