JP2009171985A5 - - Google Patents
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- Publication number
- JP2009171985A5 JP2009171985A5 JP2009113021A JP2009113021A JP2009171985A5 JP 2009171985 A5 JP2009171985 A5 JP 2009171985A5 JP 2009113021 A JP2009113021 A JP 2009113021A JP 2009113021 A JP2009113021 A JP 2009113021A JP 2009171985 A5 JP2009171985 A5 JP 2009171985A5
- Authority
- JP
- Japan
- Prior art keywords
- oncogene
- proto
- lung
- probe
- primer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000523 sample Substances 0.000 claims 26
- 238000000034 method Methods 0.000 claims 24
- 102000052575 Proto-Oncogene Human genes 0.000 claims 20
- 108700020978 Proto-Oncogene Proteins 0.000 claims 20
- 206010028980 Neoplasm Diseases 0.000 claims 13
- 210000005265 lung cell Anatomy 0.000 claims 12
- 230000000295 complement effect Effects 0.000 claims 10
- 208000020816 lung neoplasm Diseases 0.000 claims 10
- 208000037841 lung tumor Diseases 0.000 claims 10
- 210000004881 tumor cell Anatomy 0.000 claims 10
- 108091033319 polynucleotide Proteins 0.000 claims 6
- 102000040430 polynucleotide Human genes 0.000 claims 6
- 239000002157 polynucleotide Substances 0.000 claims 6
- 108010005525 8-oxodGTPase Proteins 0.000 claims 5
- 102100023174 Methionine aminopeptidase 2 Human genes 0.000 claims 5
- 108090000192 Methionyl aminopeptidases Proteins 0.000 claims 5
- 102100039792 Oxidized purine nucleoside triphosphate hydrolase Human genes 0.000 claims 5
- 102100025038 Ubiquitin carboxyl-terminal hydrolase isozyme L1 Human genes 0.000 claims 5
- 101710186825 Ubiquitin carboxyl-terminal hydrolase isozyme L1 Proteins 0.000 claims 5
- 238000001514 detection method Methods 0.000 claims 4
- 108020004999 messenger RNA Proteins 0.000 claims 4
- 230000002018 overexpression Effects 0.000 claims 4
- 206010059866 Drug resistance Diseases 0.000 claims 3
- 230000032823 cell division Effects 0.000 claims 3
- 229940124606 potential therapeutic agent Drugs 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000002299 complementary DNA Substances 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 238000002405 diagnostic procedure Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 238000010839 reverse transcription Methods 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 231100000588 tumorigenic Toxicity 0.000 claims 1
- 230000000381 tumorigenic effect Effects 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8004498P | 1998-03-31 | 1998-03-31 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000540746A Division JP2002509706A (ja) | 1998-03-31 | 1999-03-30 | 肺癌の診断及び治療方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012096852A Division JP2012147796A (ja) | 1998-03-31 | 2012-04-20 | 肺癌の診断及び治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009171985A JP2009171985A (ja) | 2009-08-06 |
| JP2009171985A5 true JP2009171985A5 (https=) | 2011-04-14 |
Family
ID=22154908
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000540746A Pending JP2002509706A (ja) | 1998-03-31 | 1999-03-30 | 肺癌の診断及び治療方法 |
| JP2009113021A Pending JP2009171985A (ja) | 1998-03-31 | 2009-05-07 | 肺癌の診断及び治療方法 |
| JP2012096852A Pending JP2012147796A (ja) | 1998-03-31 | 2012-04-20 | 肺癌の診断及び治療方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000540746A Pending JP2002509706A (ja) | 1998-03-31 | 1999-03-30 | 肺癌の診断及び治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012096852A Pending JP2012147796A (ja) | 1998-03-31 | 2012-04-20 | 肺癌の診断及び治療方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20070218511A1 (https=) |
| EP (1) | EP1095183B1 (https=) |
| JP (3) | JP2002509706A (https=) |
| AT (1) | ATE546544T1 (https=) |
| AU (1) | AU3217599A (https=) |
| CA (2) | CA2323058C (https=) |
| WO (1) | WO1999049774A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002079504A2 (en) * | 2001-03-30 | 2002-10-10 | Dalhousie University | Neotic and endoapoptotic cells and detection of neosis and endoapoptosis |
| US7202045B2 (en) * | 2001-09-19 | 2007-04-10 | Regents Of The University Of Michigan | Detection and treatment of cancers of the lung |
| EP2075340A3 (en) * | 2003-09-30 | 2009-07-08 | Sbarro Health Research Organization | Gene modulation by RB2/p 130 expression |
| JP6702932B2 (ja) * | 2017-12-27 | 2020-06-03 | 富士フイルム株式会社 | 細胞撮像制御装置および方法並びにプログラム |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) * | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) * | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) * | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) * | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4277437A (en) * | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4275149A (en) * | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4366241A (en) * | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| DE3424893A1 (de) * | 1984-07-06 | 1986-02-06 | Agfa-Gevaert Ag, 5090 Leverkusen | Photographisches silberhalogenidaufzeichnungsmaterial |
| US5274087A (en) * | 1986-08-13 | 1993-12-28 | Molecular Diagnostics, Inc. | cDNA coding for carcinoembryonic antigen (CEA) |
| US5223482A (en) * | 1986-11-17 | 1993-06-29 | Scios Nova Inc. | Recombinant Alzheimer's protease inhibitory amyloid protein and method of use |
| JPH0253486A (ja) * | 1988-08-19 | 1990-02-22 | Rikagaku Kenkyusho | ヒトｍｙｂ関連遺伝子 |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US6040138A (en) | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| US5578444A (en) * | 1991-06-27 | 1996-11-26 | Genelabs Technologies, Inc. | Sequence-directed DNA-binding molecules compositions and methods |
| US5412087A (en) | 1992-04-24 | 1995-05-02 | Affymax Technologies N.V. | Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces |
| US6114114A (en) | 1992-07-17 | 2000-09-05 | Incyte Pharmaceuticals, Inc. | Comparative gene transcript analysis |
| AU5136693A (en) * | 1992-10-01 | 1994-04-26 | Thomas Jefferson University | Antisense oligonucleotides to b myb proto-oncogene |
| US5578832A (en) | 1994-09-02 | 1996-11-26 | Affymetrix, Inc. | Method and apparatus for imaging a sample on a device |
| US5631734A (en) | 1994-02-10 | 1997-05-20 | Affymetrix, Inc. | Method and apparatus for detection of fluorescently labeled materials |
| US5734039A (en) * | 1994-09-15 | 1998-03-31 | Thomas Jefferson University | Antisense oligonucleotides targeting cooperating oncogenes |
| US5795716A (en) | 1994-10-21 | 1998-08-18 | Chee; Mark S. | Computer-aided visualization and analysis system for sequence evaluation |
| US5695980A (en) * | 1995-06-06 | 1997-12-09 | Human Genome Sciences | Polynucleotides, vectors, cells and an expression method for human MutT2 |
| CA2178022A1 (en) | 1995-06-01 | 1996-12-02 | Michael Hayden | Mouse model for huntington's disease and related dna sequences |
| US5695937A (en) * | 1995-09-12 | 1997-12-09 | The Johns Hopkins University School Of Medicine | Method for serial analysis of gene expression |
| US5888796A (en) * | 1996-01-31 | 1999-03-30 | St. Louis University | Clone of a nucleotide sequence encoding a protein having two functions |
| US5985567A (en) * | 1997-08-15 | 1999-11-16 | Beckman Coulter, Inc. | Hybridization detection by pretreating bound single-stranded probes |
| JP2002509707A (ja) * | 1998-03-31 | 2002-04-02 | ジェンザイム・コーポレーション | 肺腫瘍細胞を同定するための組成物および方法 |
| US20040166527A1 (en) * | 1999-03-30 | 2004-08-26 | Beaudry Gary A. | Compositions and methods for the identification of lung tumor cells |
| EP2075340A3 (en) * | 2003-09-30 | 2009-07-08 | Sbarro Health Research Organization | Gene modulation by RB2/p 130 expression |
-
1999
- 1999-03-30 EP EP99914292A patent/EP1095183B1/en not_active Expired - Lifetime
- 1999-03-30 JP JP2000540746A patent/JP2002509706A/ja active Pending
- 1999-03-30 AT AT99914292T patent/ATE546544T1/de active
- 1999-03-30 WO PCT/US1999/006947 patent/WO1999049774A2/en not_active Ceased
- 1999-03-30 CA CA2323058A patent/CA2323058C/en not_active Expired - Fee Related
- 1999-03-30 CA CA2735260A patent/CA2735260A1/en not_active Abandoned
- 1999-03-30 AU AU32175/99A patent/AU3217599A/en not_active Abandoned
-
2006
- 2006-08-14 US US11/504,260 patent/US20070218511A1/en not_active Abandoned
-
2009
- 2009-05-07 JP JP2009113021A patent/JP2009171985A/ja active Pending
- 2009-08-20 US US12/545,028 patent/US7846667B2/en not_active Expired - Fee Related
-
2010
- 2010-11-22 US US12/951,449 patent/US8067240B2/en not_active Expired - Fee Related
-
2012
- 2012-04-20 JP JP2012096852A patent/JP2012147796A/ja active Pending
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