JP2002509706A - 肺癌の診断及び治療方法 - Google Patents

肺癌の診断及び治療方法

Info

Publication number
JP2002509706A
JP2002509706A JP2000540746A JP2000540746A JP2002509706A JP 2002509706 A JP2002509706 A JP 2002509706A JP 2000540746 A JP2000540746 A JP 2000540746A JP 2000540746 A JP2000540746 A JP 2000540746A JP 2002509706 A JP2002509706 A JP 2002509706A
Authority
JP
Japan
Prior art keywords
proto
oncogene
cell
sequence
lung
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000540746A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002509706A5 (https=
Inventor
ジン ジェン
ゲアリー エイ ビュードリー
スティーヴン エル マーデン
アーサー エイチ バーテルセン
Original Assignee
ジンザイム コーポレイション
ジョン ホプキンズ ユニヴァーシティー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジンザイム コーポレイション, ジョン ホプキンズ ユニヴァーシティー filed Critical ジンザイム コーポレイション
Publication of JP2002509706A publication Critical patent/JP2002509706A/ja
Publication of JP2002509706A5 publication Critical patent/JP2002509706A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2000540746A 1998-03-31 1999-03-30 肺癌の診断及び治療方法 Pending JP2002509706A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8004498P 1998-03-31 1998-03-31
US60/080,044 1998-03-31
PCT/US1999/006947 WO1999049774A2 (en) 1998-03-31 1999-03-30 Methods for the diagnosis and treatment of lung cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009113021A Division JP2009171985A (ja) 1998-03-31 2009-05-07 肺癌の診断及び治療方法

Publications (2)

Publication Number Publication Date
JP2002509706A true JP2002509706A (ja) 2002-04-02
JP2002509706A5 JP2002509706A5 (https=) 2009-06-25

Family

ID=22154908

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2000540746A Pending JP2002509706A (ja) 1998-03-31 1999-03-30 肺癌の診断及び治療方法
JP2009113021A Pending JP2009171985A (ja) 1998-03-31 2009-05-07 肺癌の診断及び治療方法
JP2012096852A Pending JP2012147796A (ja) 1998-03-31 2012-04-20 肺癌の診断及び治療方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2009113021A Pending JP2009171985A (ja) 1998-03-31 2009-05-07 肺癌の診断及び治療方法
JP2012096852A Pending JP2012147796A (ja) 1998-03-31 2012-04-20 肺癌の診断及び治療方法

Country Status (7)

Country Link
US (3) US20070218511A1 (https=)
EP (1) EP1095183B1 (https=)
JP (3) JP2002509706A (https=)
AT (1) ATE546544T1 (https=)
AU (1) AU3217599A (https=)
CA (2) CA2323058C (https=)
WO (1) WO1999049774A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002079504A2 (en) * 2001-03-30 2002-10-10 Dalhousie University Neotic and endoapoptotic cells and detection of neosis and endoapoptosis
US7202045B2 (en) * 2001-09-19 2007-04-10 Regents Of The University Of Michigan Detection and treatment of cancers of the lung
EP2075340A3 (en) * 2003-09-30 2009-07-08 Sbarro Health Research Organization Gene modulation by RB2/p 130 expression
JP6702932B2 (ja) * 2017-12-27 2020-06-03 富士フイルム株式会社 細胞撮像制御装置および方法並びにプログラム

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0253486A (ja) * 1988-08-19 1990-02-22 Rikagaku Kenkyusho ヒトmyb関連遺伝子
US5695937A (en) * 1995-09-12 1997-12-09 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression

Family Cites Families (28)

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Publication number Priority date Publication date Assignee Title
NL154598B (nl) * 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) * 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) * 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4277437A (en) * 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4275149A (en) * 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
DE3424893A1 (de) * 1984-07-06 1986-02-06 Agfa-Gevaert Ag, 5090 Leverkusen Photographisches silberhalogenidaufzeichnungsmaterial
US5274087A (en) * 1986-08-13 1993-12-28 Molecular Diagnostics, Inc. cDNA coding for carcinoembryonic antigen (CEA)
US5223482A (en) * 1986-11-17 1993-06-29 Scios Nova Inc. Recombinant Alzheimer's protease inhibitory amyloid protein and method of use
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US5578444A (en) * 1991-06-27 1996-11-26 Genelabs Technologies, Inc. Sequence-directed DNA-binding molecules compositions and methods
US5412087A (en) 1992-04-24 1995-05-02 Affymax Technologies N.V. Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces
US6114114A (en) 1992-07-17 2000-09-05 Incyte Pharmaceuticals, Inc. Comparative gene transcript analysis
AU5136693A (en) * 1992-10-01 1994-04-26 Thomas Jefferson University Antisense oligonucleotides to b myb proto-oncogene
US5578832A (en) 1994-09-02 1996-11-26 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
US5631734A (en) 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US5734039A (en) * 1994-09-15 1998-03-31 Thomas Jefferson University Antisense oligonucleotides targeting cooperating oncogenes
US5795716A (en) 1994-10-21 1998-08-18 Chee; Mark S. Computer-aided visualization and analysis system for sequence evaluation
US5695980A (en) * 1995-06-06 1997-12-09 Human Genome Sciences Polynucleotides, vectors, cells and an expression method for human MutT2
CA2178022A1 (en) 1995-06-01 1996-12-02 Michael Hayden Mouse model for huntington's disease and related dna sequences
US5888796A (en) * 1996-01-31 1999-03-30 St. Louis University Clone of a nucleotide sequence encoding a protein having two functions
US5985567A (en) * 1997-08-15 1999-11-16 Beckman Coulter, Inc. Hybridization detection by pretreating bound single-stranded probes
JP2002509707A (ja) * 1998-03-31 2002-04-02 ジェンザイム・コーポレーション 肺腫瘍細胞を同定するための組成物および方法
US20040166527A1 (en) * 1999-03-30 2004-08-26 Beaudry Gary A. Compositions and methods for the identification of lung tumor cells
EP2075340A3 (en) * 2003-09-30 2009-07-08 Sbarro Health Research Organization Gene modulation by RB2/p 130 expression

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0253486A (ja) * 1988-08-19 1990-02-22 Rikagaku Kenkyusho ヒトmyb関連遺伝子
US5695937A (en) * 1995-09-12 1997-12-09 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression

Also Published As

Publication number Publication date
US20070218511A1 (en) 2007-09-20
EP1095183B1 (en) 2012-02-22
WO1999049774A9 (en) 2000-02-24
US8067240B2 (en) 2011-11-29
CA2323058A1 (en) 1999-10-07
US20110091892A1 (en) 2011-04-21
WO1999049774A2 (en) 1999-10-07
EP1095183A4 (en) 2004-09-15
US20100062443A1 (en) 2010-03-11
JP2009171985A (ja) 2009-08-06
EP1095183A2 (en) 2001-05-02
JP2012147796A (ja) 2012-08-09
US7846667B2 (en) 2010-12-07
AU3217599A (en) 1999-10-18
CA2323058C (en) 2011-03-29
ATE546544T1 (de) 2012-03-15
WO1999049774A3 (en) 1999-12-29
CA2735260A1 (en) 1999-10-07

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