JP2009062339A - Composition for oral cavity - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a composition for oral cavity to be used as a detifrice or the like, which contains cranberry (Vaccinium macrocarpon) dry powder and only using materials safe to human health even if swallowed, wherein the cranberry is hardly put to color fading. <P>SOLUTION: The composition for oral cavity contains cranberry dry powder and glycosylrutin. Alternatively, the composition for oral cavity contains cranberry dry powder, hematococcus algae extract and glycosylrutin. The composition is usable for preventing or treating periodontal diseases and dental caries. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention is an oral composition used as a dentifrice and the like, and contains a dry powder of cranberries as an oral preparation, and uses only materials that are safe for the human body when swallowed, In addition, the color of the cranberries is less likely to fade.

  In patent document 1, what consists of a dry powder of cranberries or a solvent extract is described as an agent for inhibiting coaggregation of oral bacteria.

  Patent Document 2 describes an oral composition using a natural product that exists in nature, such as hinokitiol and lemongrass citral, and has been used by humans and has been confirmed to be safe.

In Non-Patent Document 1, regarding bacterial flora closely related to the causes of caries and periodontal disease, there are cranberry effects, that is, bacterial tooth surface adhesion inhibitory effect, bacterial growth inhibitory effect, oral streptococcal biofilm formation inhibitory effect. Are listed.
JP 2006-199661 A JP 2007-63166 A JP 2001-342142 A "FOOD STYLE 21 (August 2004 issue)" issued by Food Chemical Newspaper, pages 44-46

  The invention of the present application contains dry cranberry powder as an oral preparation used for dentifrices, etc., and only uses materials that are safe for the human body when swallowed, and the color of cranberries is less likely to fade It is an issue to provide.

  An oral composition comprising a dry cranberry powder and glycosyl rutin is provided.

  An oral composition comprising a dried cranberry powder, an extract of Haematococcus alga and glycosyl rutin is provided.

  The present invention also provides an oral composition comprising a dried cranberry powder and glycosyl rutin, which is used for the prevention or treatment of periodontal disease.

  Furthermore, the composition for oral cavity characterized by containing cranberry dry powder and glycosyl rutin, The composition for oral cavity according to claim 2, which is used for prevention or treatment of dental caries.

  Cranberry dry powder has been reported as a composition for preventing and treating urological diseases (Patent Document 3), and also reported to be suitable for prevention of bacterial flora closely related to the causes of dental caries and periodontal disease as described above. Is done.

  Cranberries are crimson in color. From the standpoint of using only materials that are safe for the human body when swallowed, it is most desirable to use the color of cranberry as it is in the product, as it increases the product value. When it is necessary to assist color development, it is necessary to use materials that are safe for the human body.

  Therefore, as a result of experiments as described later, it was found that addition of glycosylrutin to the dried cranberry powder effectively prevents the color of the cranberries from fading.

  In the present invention, only a material safe for the human body is used without using a surfactant, an abrasive and a foaming agent. On the other hand, ingredients for preventing dental caries, bad breath, and mouth washing are effectively contained. For example, when it is used for toothpaste, it can be swallowed without gargle and can be brushed without using water, so it is very suitable for use by infants and elderly people requiring care. The color of cranberries is effectively maintained using glycosyl rutin, which is safe for humans, or Haematococcus alga extract.

Example 1
Ph 4.3 ± 0.2 at 40 ° C, water as solvent, glycerin and sorbitol as wetting agent, xanthan gum as adhesive, L menthol and spearmint oil as flavoring agent, potassium glycyrrhizinate as sweetening agent , Sodium citrate was used as a ph regulator, and xylitol was used as an active ingredient for oral bacteria. Cranberry juice powder was used as an active ingredient.
Table 1 shows the color change recorded day by day.

(Example 2)
Ph 4.3 ± 0.2 at 40 ° C, water as solvent, glycerin and sorbitol as wetting agent, xanthan gum as adhesive, L menthol and spearmint oil as flavoring agent, potassium glycyrrhizinate as sweetening agent , Sodium citrate was used as a ph regulator, and xylitol was used as an active ingredient for oral bacteria. Cranberry juice powder was used as an active ingredient. In addition, Haematococcus alga extract was added as a supplement to the color of the cranberry juice powder.
The change in color was recorded day by day as shown in Table 2.

(Example 3)
Ph 4.3 ± 0.2 at 40 ° C, water as solvent, glycerin and sorbitol as wetting agent, xanthan gum as adhesive, L menthol and spearmint oil as flavoring agent, potassium glycyrrhizinate as sweetening agent , Sodium citrate was used as a ph regulator, and xylitol was used as an active ingredient for oral bacteria. Cranberry juice powder was used as an active ingredient. In addition, Haematococcus alga extract was added as a supplement to the color of the cranberry juice powder. Glycosyl rutin was added to suppress the color change of cranberry juice.
The change in color was recorded day by day, as shown in Table 3.

Example 4
Ph 4.3 ± 0.2 at 40 ° C, water as solvent, glycerin and sorbitol as wetting agent, xanthan gum as adhesive, L menthol and spearmint oil as flavoring agent, potassium glycyrrhizinate as sweetening agent , Sodium citrate was used as a ph regulator, and xylitol was used as an active ingredient for oral bacteria. Cranberry juice powder and glycosyl rutin were used as active ingredients. In addition, Haematococcus alga extract was added as a supplement to the color of the cranberry juice powder. Glycosyl rutin and vitamin E (tocopherol) were added to suppress the color change of cranberry juice.
Table 4 shows the color change recorded day by day.

  Examples 1 to 4 are accelerated tests conducted to predict discoloration at room temperature. When only cranberry juice powder was used, the color almost disappeared after several days and disappeared after several tens of days (Example 1 [Table 1]). When a Haematococcus alga extract was added to assist color development, the color was maintained for several tens of days, but some fading was observed (Example 2 [Table 2]). When glycotyrrhizin was added, the color was maintained for about 90 days (Example 3 [Table 3]). Vitamin E did not affect the color change (Example 4 [Table 4]).

  As shown in the table, the color disappeared in a short period of time with cranberry juice powder, but the color maintenance was significant when hematococcus extract was added, and color maintenance sufficient to maintain the product value when glycosyl rutin was added Was seen. When the oral composition according to the present invention is used, for example, for toothpaste, it is sufficient that the color is maintained at room temperature for approximately 1.5 years.

Claims (4)

An oral composition comprising a dried cranberry powder and glycosyl rutin. An oral composition comprising a dried cranberry powder, an extract of Haematococcus alga and glycosyl rutin. The composition for oral cavity according to claim 1 or 2, which is used for prevention or treatment of periodontal disease. The composition for oral cavity according to claim 1 or 2, which is used for caries prevention or treatment.