JP2008546694A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008546694A5 JP2008546694A5 JP2008516976A JP2008516976A JP2008546694A5 JP 2008546694 A5 JP2008546694 A5 JP 2008546694A5 JP 2008516976 A JP2008516976 A JP 2008516976A JP 2008516976 A JP2008516976 A JP 2008516976A JP 2008546694 A5 JP2008546694 A5 JP 2008546694A5
- Authority
- JP
- Japan
- Prior art keywords
- dione
- diene
- oxy
- fluoro
- bis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69054505P | 2005-06-14 | 2005-06-14 | |
| PCT/US2006/022790 WO2006138212A1 (en) | 2005-06-14 | 2006-06-12 | SUBSTITUTED PHENYLPHOSPHATES AS MUTUAL PRODRUGS OF STEROIDS AND β -AGONISTS FOR THE TREATMENT OF PULMONARY INFLAMMATION AND BRONCHOCONSTRICTION |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008546694A JP2008546694A (ja) | 2008-12-25 |
| JP2008546694A5 true JP2008546694A5 (OSRAM) | 2009-07-23 |
Family
ID=37570763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008516976A Pending JP2008546694A (ja) | 2005-06-14 | 2006-06-12 | 肺炎及び気管支の治療のためのステロイド及びβ−アゴニストの相互プロドラッグとしての置換されたフェニルホスファート |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20100209508A1 (OSRAM) |
| EP (1) | EP1893220A4 (OSRAM) |
| JP (1) | JP2008546694A (OSRAM) |
| KR (1) | KR20060130515A (OSRAM) |
| CN (1) | CN101227912A (OSRAM) |
| AR (1) | AR054475A1 (OSRAM) |
| AU (1) | AU2006259604A1 (OSRAM) |
| BR (1) | BRPI0611567A2 (OSRAM) |
| CA (1) | CA2612364A1 (OSRAM) |
| IL (1) | IL187816A0 (OSRAM) |
| NO (1) | NO20080182L (OSRAM) |
| RU (1) | RU2008100237A (OSRAM) |
| TW (1) | TW200718707A (OSRAM) |
| WO (1) | WO2006138212A1 (OSRAM) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2663737A1 (en) * | 2006-09-19 | 2008-03-27 | Cipla Limited | Processes for the preparation of ciclesonide and its crystal form |
| EP2114972A2 (en) * | 2006-12-13 | 2009-11-11 | Gilead Sciences, Inc. | Monophosphates as mutual prodrugs of muscarinic receptor antagonists and beta-agonists for the treatment of copd and chronic bronchitis |
| US20100098641A1 (en) * | 2006-12-13 | 2010-04-22 | William Baker | Monophosphates as Mutual Prodrugs of Anti-Inflammatory Signal Transduction Modulators (AISTM's) and Beta-Agonists for the Treatment of Pulmonary Inflammation and Bronchoconstriction |
| CL2008003802A1 (es) * | 2007-12-21 | 2010-02-19 | Schering Corp | Compuestos derivados de tioeteres c-21, agonistas del receptor de glucocorticoide; composicion farmaceutica; y uso para el tratamiento o profilaxis de una enfermedad o afeccion inmune, autoinmune o inflamatoria, tales como artritis reumatoide y esclerosis multiple. |
| AR069804A1 (es) * | 2007-12-21 | 2010-02-17 | Schering Corp | Agonistas del receptor glucocorticoide c20- c21 sustituido |
| US20090318396A1 (en) * | 2008-06-10 | 2009-12-24 | Gilead Sciences, Inc. | Corticosteroid linked beta-agonist compounds for use in therapy |
| WO2010126953A1 (en) * | 2009-04-29 | 2010-11-04 | Gilead Sciences, Inc. | Corticosteroid linked beta-agonist compounds for use in therapy |
| WO2010132743A1 (en) * | 2009-05-15 | 2010-11-18 | Gilead Sciences, Inc. | Corticosteroid beta-agonist compounds for use in therapy |
| EP2443134A2 (en) * | 2009-06-16 | 2012-04-25 | Schering Corporation | NOVEL [3,2-c]HETEROARYL STEROIDS AS GLUCOCORTICOID RECEPTOR AGONISTS, COMPOSITIONS AND USES THEREOF |
| EP2993178A1 (en) | 2009-09-11 | 2016-03-09 | CHIESI FARMACEUTICI S.p.A. | Glucocorticoid condensed in position 16,17 with an isoxazolidine group |
| WO2011081937A1 (en) | 2009-12-15 | 2011-07-07 | Gilead Sciences, Inc. | Corticosteroid-beta-agonist-muscarinic antagonist compounds for use in therapy |
| JP6124176B2 (ja) * | 2013-03-26 | 2017-05-10 | 株式会社伏見製薬所 | 樹脂成形体用組成物 |
| CN104510726A (zh) * | 2013-09-27 | 2015-04-15 | 张金华 | 一种用于清洁呼吸道系统的食盐干粉吸入剂 |
| PT107567B (pt) * | 2014-03-31 | 2019-02-13 | Hovione Farm S A | Secador por atomização com atomizador múltiplo, método para o aumento de escala de pós para inalação secos por dispositivo de atomização múltiplo e uso de vários atomizadores num secador por atomização |
| PE20190622A1 (es) | 2016-06-02 | 2019-04-26 | Abbvie Inc | Agonista del receptor de glucocorticoides e inmunoconjugados del mismo |
| KR20250114431A (ko) * | 2016-11-08 | 2025-07-29 | 리제너론 파마슈티칼스 인코포레이티드 | 스테로이드 및 이의 단백질-접합체 |
| KR20200007905A (ko) | 2017-05-18 | 2020-01-22 | 리제너론 파마슈티칼스 인코포레이티드 | 사이클로덱스트린 단백질 약물 접합체 |
| IL313068A (en) | 2017-11-07 | 2024-07-01 | Regeneron Pharma | Hydrophilic linkers for antibody drug conjugates |
| MA49796A (fr) | 2017-12-01 | 2020-06-03 | Abbvie Inc | Agoniste du récepteur des glucocorticoïdes et immunoconjugués de celui-ci |
| IL275757B2 (en) | 2018-01-08 | 2025-08-01 | Regeneron Pharma | Steroids and antibody-conjugates thereof |
| MX2020011546A (es) | 2018-05-09 | 2021-01-29 | Regeneron Pharma | Anticuerpos anti-msr1 y metodos de uso de los mismos. |
| IT201900014178A1 (it) * | 2019-08-06 | 2021-02-06 | Genetic S P A | Esteri del montelukast e loro formulazioni farmaceutiche |
| JP7656784B2 (ja) * | 2020-11-26 | 2025-04-04 | 国立医薬品食品衛生研究所長 | 新規化合物及び抗コロナウイルス剤 |
| CN112592280B (zh) * | 2020-12-09 | 2023-05-23 | 青岛职业技术学院 | 一种消旋沙丁胺醇的制备方法 |
| TWI899455B (zh) | 2021-03-23 | 2025-10-01 | 美商美國禮來大藥廠 | 糖皮質素受體激動劑 |
| AR125079A1 (es) | 2021-03-23 | 2023-06-07 | Lilly Co Eli | Agonistas de receptores de glucocorticoides sustituidos con carboxi |
| AR125084A1 (es) | 2021-03-23 | 2023-06-07 | Lilly Co Eli | Agonistas del receptor de glucocorticoides novedosos |
| CN117580849A (zh) * | 2021-06-24 | 2024-02-20 | 江苏先声药业有限公司 | 甾体类化合物、其药物组合物及其应用 |
| CN118201943A (zh) * | 2021-09-14 | 2024-06-14 | 映恩生物制药（苏州）有限公司 | 一种抗炎症的化合物及其用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE585432A (fr) * | 1958-12-08 | 1960-06-08 | American Cyanamid Co | Stéroïdes fluorés. |
| US4757079A (en) * | 1986-06-24 | 1988-07-12 | Dynamac Corporaton | Anti-hypertensive piperidine compounds |
| GR1001529B (el) * | 1990-09-07 | 1994-03-31 | Elmuquimica Farm Sl | Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης. |
| ATE172739T1 (de) * | 1993-04-02 | 1998-11-15 | Byk Gulden Lomberg Chem Fab | Neue prednisolonderivate |
| US6300326B1 (en) * | 1994-11-02 | 2001-10-09 | Michael R. Dobbs | Composition and method for control and treatment of cutaneous inflammation |
| IT1303671B1 (it) * | 1998-07-28 | 2001-02-23 | Nicox Sa | Sali dell'acido nitrico con farmaci attivi nel trattamento dipatologie del sistema respiratorio |
| US20060293293A1 (en) * | 2003-05-22 | 2006-12-28 | Altana Pharma Ag | Salmeterol and ciclesonide combination |
| WO2005028495A1 (en) * | 2003-09-24 | 2005-03-31 | Glaxo Group Limited | Anti-inflammatory glucocorticoids |
| WO2005063777A1 (en) * | 2003-12-23 | 2005-07-14 | Corus Pharma | Benzylphosphate and substituted benzylphosphate prodrugs for the treatment of pulmonary inflammation |
-
2006
- 2006-06-12 RU RU2008100237/04A patent/RU2008100237A/ru not_active Application Discontinuation
- 2006-06-12 EP EP06784777A patent/EP1893220A4/en not_active Withdrawn
- 2006-06-12 CA CA002612364A patent/CA2612364A1/en not_active Abandoned
- 2006-06-12 WO PCT/US2006/022790 patent/WO2006138212A1/en not_active Ceased
- 2006-06-12 US US11/922,258 patent/US20100209508A1/en not_active Abandoned
- 2006-06-12 CN CNA2006800213783A patent/CN101227912A/zh active Pending
- 2006-06-12 BR BRPI0611567A patent/BRPI0611567A2/pt not_active IP Right Cessation
- 2006-06-12 JP JP2008516976A patent/JP2008546694A/ja active Pending
- 2006-06-12 AU AU2006259604A patent/AU2006259604A1/en not_active Abandoned
- 2006-06-14 AR ARP060102527A patent/AR054475A1/es unknown
- 2006-06-14 TW TW095121230A patent/TW200718707A/zh unknown
- 2006-06-14 KR KR1020060053519A patent/KR20060130515A/ko not_active Withdrawn
-
2007
- 2007-12-02 IL IL187816A patent/IL187816A0/en unknown
-
2008
- 2008-01-11 NO NO20080182A patent/NO20080182L/no not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2008100237A (ru) | ОБЩИЕ ПРОЛЕКАРСТВЕННЫЕ ФОРМЫ СТЕРОИДОВ И β-АГОНИСТОВ (ВАРИАНТЫ), ВКЛЮЧАЮЩИЙ ИХ АЭРОЗОЛЬНЫЙ СОСТАВ (ВАРИАНТЫ) И СПОСОБ ПРЕДОТВРАЩЕНИЯ И/ИЛИ ЛЕЧЕНИЯ ЛЕГОЧНЫХ ВОСПАЛЕНИЙ И/ИЛИ БРОНХОСТЕНОЗА С ИХ ПОМОЩЬЮ | |
| JP2010510210A5 (OSRAM) | ||
| US9096639B2 (en) | 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylene phenyl derivatives, methods for the production thereof and use thereof for treating diseases | |
| JP2010529152A5 (OSRAM) | ||
| CN102532235B (zh) | 蟾毒配基衍生物及其制备方法、包含该衍生物的组合物、及其用途 | |
| JP2016034946A (ja) | ステロイド性ｃｙｐ１７阻害剤／抗アンドロゲン剤の新しいプロドラッグ | |
| JP2008510762A5 (OSRAM) | ||
| MX2009008334A (es) | Esteroides que liberan oxido nitrico. | |
| JP2009532417A5 (OSRAM) | ||
| JP2011526924A5 (OSRAM) | ||
| ES2342364T3 (es) | Conjugados de compuestos macrolidos especificos para las celulas del sistema inmunitario con compuestos antiinflamatorios, que mejoran la especificidad celular de la terapia antiinflamatoria. | |
| WO2009082818A8 (en) | Novel c-21-keto lupane derivatives preparation and use thereof | |
| EP2294077A1 (en) | Corticosteroid linked beta-agonist compounds for use in therapy | |
| JPH08507790A (ja) | 大環状カルバメート免疫調節剤 | |
| JP2008500366A5 (OSRAM) | ||
| JP2014510746A5 (OSRAM) | ||
| JP2015509075A5 (OSRAM) | ||
| WO2014102592A2 (en) | Oxime/substituted quinoxaline-type piperidine compounds and uses thereof | |
| JP2020529418A5 (ja) | Ｔ細胞急性リンパ芽球性白血病を治療するための化合物、組成物及び方法 | |
| EA015622B1 (ru) | Азагетероциклильные производные андростанов и андростенов в качестве лекарственных средств от сердечно-сосудистых расстройств | |
| US20150051179A1 (en) | Novel steroidal cyp17 inhibitors/antiandrogens | |
| KR101107336B1 (ko) | 항염증 작용이 있는 마크로라이드 복합체 | |
| ES2300877T3 (es) | Derivados de esteroides glucosilados con actividad antimigratoria. | |
| JP2010514734A5 (OSRAM) | ||
| JP2011518843A5 (OSRAM) |