JP2008545000A5 - - Google Patents
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- Publication number
- JP2008545000A5 JP2008545000A5 JP2008519857A JP2008519857A JP2008545000A5 JP 2008545000 A5 JP2008545000 A5 JP 2008545000A5 JP 2008519857 A JP2008519857 A JP 2008519857A JP 2008519857 A JP2008519857 A JP 2008519857A JP 2008545000 A5 JP2008545000 A5 JP 2008545000A5
- Authority
- JP
- Japan
- Prior art keywords
- ccr7 receptor
- cell
- tumor cells
- cells
- ccr7
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 claims 11
- 108010017158 CCR7 Receptors Proteins 0.000 claims 9
- 102000004428 CCR7 Receptors Human genes 0.000 claims 9
- 208000025205 Mantle-Cell Lymphoma Diseases 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 6
- 210000004881 tumor cell Anatomy 0.000 claims 6
- 238000000034 method Methods 0.000 claims 5
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 230000006907 apoptotic process Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2005/007371 WO2007003216A1 (en) | 2005-07-06 | 2005-07-06 | Anti-ccr7 receptor antibodies for the treatment of cancer |
| EPPCT/EP2005/007371 | 2005-07-06 | ||
| PCT/EP2006/006556 WO2007003426A1 (en) | 2005-07-06 | 2006-07-05 | Anti-ccr7 receptor antibodies for the treatment of cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008545000A JP2008545000A (ja) | 2008-12-11 |
| JP2008545000A5 true JP2008545000A5 (enExample) | 2009-11-12 |
| JP5249025B2 JP5249025B2 (ja) | 2013-07-31 |
Family
ID=36021798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008519857A Active JP5249025B2 (ja) | 2005-07-06 | 2006-07-05 | ガンを治療するための抗ｃｃｒ７受容体抗体 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8066996B2 (enExample) |
| EP (1) | EP1904102B1 (enExample) |
| JP (1) | JP5249025B2 (enExample) |
| KR (1) | KR20080030655A (enExample) |
| CN (1) | CN101257923A (enExample) |
| AT (1) | ATE453407T1 (enExample) |
| AU (1) | AU2006265281C1 (enExample) |
| BR (1) | BRPI0612632A2 (enExample) |
| CA (1) | CA2614080C (enExample) |
| DE (1) | DE602006011466D1 (enExample) |
| DK (1) | DK1904102T3 (enExample) |
| ES (1) | ES2338919T3 (enExample) |
| IL (1) | IL188594A (enExample) |
| PT (1) | PT1904102E (enExample) |
| RU (1) | RU2404808C2 (enExample) |
| WO (2) | WO2007003216A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1855694B1 (en) | 2005-02-09 | 2020-12-02 | Sarepta Therapeutics, Inc. | Antisense composition for treating muscle atrophy |
| EP2285403A2 (en) * | 2008-05-14 | 2011-02-23 | Msm Protein Technologies, Inc. | Human monoclonal antibodies against human chemokine receptor ccr7 |
| US9101559B2 (en) | 2009-05-08 | 2015-08-11 | New York University | Leukemic cell CNS infiltration controlled by notch-induced chemotaxis |
| JP5801202B2 (ja) * | 2009-09-29 | 2015-10-28 | 学校法人慶應義塾 | 抗腫瘍剤およびそのスクリーニング方法 |
| JP5315495B2 (ja) * | 2010-09-28 | 2013-10-16 | 積水化学工業株式会社 | 抗ヒトｃｃｒ７抗体、ハイブリドーマ、核酸、ベクター、細胞、医薬組成物、並びに、抗体固定化担体 |
| US20130085139A1 (en) | 2011-10-04 | 2013-04-04 | Royal Holloway And Bedford New College | Oligomers |
| WO2014151834A2 (en) * | 2013-03-15 | 2014-09-25 | Amgen Inc. | Methods and compositions relating to anti-ccr7 antigen binding proteins |
| JP6618191B2 (ja) * | 2014-03-27 | 2019-12-11 | 国立研究開発法人医薬基盤・健康・栄養研究所 | 脳マラリアの診断および治療 |
| MA41795A (fr) | 2015-03-18 | 2018-01-23 | Sarepta Therapeutics Inc | Exclusion d'un exon induite par des composés antisens dans la myostatine |
| HUE051920T2 (hu) | 2015-08-10 | 2021-03-29 | Pepmab B V | Humanizált, CCR7 receptor elleni antitestek |
| EA201890908A1 (ru) | 2015-10-09 | 2018-10-31 | Сарепта Терапьютикс, Инк. | Композиции и способы для лечения мышечной дистрофии дюшенна и сходных нарушений |
| WO2018073248A1 (en) | 2016-10-17 | 2018-04-26 | Icm (Institut Du Cerveau Et De La Moelle Épinière) | Prognosis of demyelinating diseases patients and treatment thereof |
| JOP20190187A1 (ar) * | 2017-02-03 | 2019-08-01 | Novartis Ag | مترافقات عقار جسم مضاد لـ ccr7 |
| US20220064311A1 (en) * | 2018-12-18 | 2022-03-03 | Catapult Therapeutics B.V. | The use of anti-CCR7 mabs for the prevention or treatment of graft-versus-host disease (GvHD) |
| US20230181756A1 (en) * | 2020-04-30 | 2023-06-15 | Novartis Ag | Ccr7 antibody drug conjugates for treating cancer |
| CN119390838B (zh) * | 2024-05-29 | 2025-06-10 | 锐胜科生物医药(上海)有限公司 | 一种靶向ccr7的纳米抗体及其制备与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7163681B2 (en) * | 2000-08-07 | 2007-01-16 | Centocor, Inc. | Anti-integrin antibodies, compositions, methods and uses |
| FR2818747B1 (fr) * | 2000-12-26 | 2003-05-16 | Molecular Engines Laboratoires | Procede de criblage base sur l'interaction siah-numb |
| US20020168358A1 (en) * | 2001-04-30 | 2002-11-14 | Gladue Ronald P. | Treatment of T-cell mediated diseases |
| DE10248751A1 (de) * | 2002-10-18 | 2004-05-06 | Berdel, Wolfgang E., Prof. Dr.med. | Dyslokalisationsmoleküle und deren Verwendung |
| WO2004104574A2 (en) * | 2003-05-23 | 2004-12-02 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with c-c chemokine receptor type 7 (ccr7) |
| JP5049011B2 (ja) * | 2003-06-11 | 2012-10-17 | ザ ユニバーシティー オブ シカゴ | 変異体ｌｉｇｈｔによるｔ細胞腫瘍浸潤の増大 |
-
2005
- 2005-07-06 WO PCT/EP2005/007371 patent/WO2007003216A1/en not_active Ceased
-
2006
- 2006-07-05 DK DK06776128.8T patent/DK1904102T3/da active
- 2006-07-05 CA CA2614080A patent/CA2614080C/en active Active
- 2006-07-05 EP EP06776128A patent/EP1904102B1/en active Active
- 2006-07-05 DE DE602006011466T patent/DE602006011466D1/de active Active
- 2006-07-05 US US11/994,833 patent/US8066996B2/en active Active
- 2006-07-05 WO PCT/EP2006/006556 patent/WO2007003426A1/en not_active Ceased
- 2006-07-05 JP JP2008519857A patent/JP5249025B2/ja active Active
- 2006-07-05 CN CNA2006800323035A patent/CN101257923A/zh active Pending
- 2006-07-05 ES ES06776128T patent/ES2338919T3/es active Active
- 2006-07-05 BR BRPI0612632-4A patent/BRPI0612632A2/pt not_active Application Discontinuation
- 2006-07-05 KR KR1020087003130A patent/KR20080030655A/ko not_active Ceased
- 2006-07-05 AU AU2006265281A patent/AU2006265281C1/en active Active
- 2006-07-05 AT AT06776128T patent/ATE453407T1/de active
- 2006-07-05 RU RU2008104420/10A patent/RU2404808C2/ru active
- 2006-07-05 PT PT06776128T patent/PT1904102E/pt unknown
-
2008
- 2008-01-03 IL IL188594A patent/IL188594A/en active IP Right Grant
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