DK1904102T3 - ANTI-CCR7-receptorantistoffer til behandling af cancer - Google Patents

ANTI-CCR7-receptorantistoffer til behandling af cancer

Info

Publication number
DK1904102T3
DK1904102T3 DK06776128.8T DK06776128T DK1904102T3 DK 1904102 T3 DK1904102 T3 DK 1904102T3 DK 06776128 T DK06776128 T DK 06776128T DK 1904102 T3 DK1904102 T3 DK 1904102T3
Authority
DK
Denmark
Prior art keywords
ccr7 receptor
cancer
treatment
receptor antibodies
antibodies
Prior art date
Application number
DK06776128.8T
Other languages
Danish (da)
English (en)
Inventor
Giral Sonia Lopez
Calleja Cecilia Munoz
Perez Manuel Jesus Alfonso
Original Assignee
Univ Madrid Autonoma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Madrid Autonoma filed Critical Univ Madrid Autonoma
Application granted granted Critical
Publication of DK1904102T3 publication Critical patent/DK1904102T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK06776128.8T 2005-07-06 2006-07-05 ANTI-CCR7-receptorantistoffer til behandling af cancer DK1904102T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2005/007371 WO2007003216A1 (en) 2005-07-06 2005-07-06 Anti-ccr7 receptor antibodies for the treatment of cancer
PCT/EP2006/006556 WO2007003426A1 (en) 2005-07-06 2006-07-05 Anti-ccr7 receptor antibodies for the treatment of cancer

Publications (1)

Publication Number Publication Date
DK1904102T3 true DK1904102T3 (da) 2010-04-19

Family

ID=36021798

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06776128.8T DK1904102T3 (da) 2005-07-06 2006-07-05 ANTI-CCR7-receptorantistoffer til behandling af cancer

Country Status (16)

Country Link
US (1) US8066996B2 (enExample)
EP (1) EP1904102B1 (enExample)
JP (1) JP5249025B2 (enExample)
KR (1) KR20080030655A (enExample)
CN (1) CN101257923A (enExample)
AT (1) ATE453407T1 (enExample)
AU (1) AU2006265281C1 (enExample)
BR (1) BRPI0612632A2 (enExample)
CA (1) CA2614080C (enExample)
DE (1) DE602006011466D1 (enExample)
DK (1) DK1904102T3 (enExample)
ES (1) ES2338919T3 (enExample)
IL (1) IL188594A (enExample)
PT (1) PT1904102E (enExample)
RU (1) RU2404808C2 (enExample)
WO (2) WO2007003216A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006213686A1 (en) 2005-02-09 2006-08-17 Avi Bio Pharma, Inc. Antisense composition and method for treating muscle atrophy
EP2285403A2 (en) * 2008-05-14 2011-02-23 Msm Protein Technologies, Inc. Human monoclonal antibodies against human chemokine receptor ccr7
US9101559B2 (en) 2009-05-08 2015-08-11 New York University Leukemic cell CNS infiltration controlled by notch-induced chemotaxis
WO2011040428A1 (ja) * 2009-09-29 2011-04-07 学校法人慶應義塾 抗腫瘍剤およびそのスクリーニング方法
JP5315495B2 (ja) * 2010-09-28 2013-10-16 積水化学工業株式会社 抗ヒトccr7抗体、ハイブリドーマ、核酸、ベクター、細胞、医薬組成物、並びに、抗体固定化担体
US20130085139A1 (en) 2011-10-04 2013-04-04 Royal Holloway And Bedford New College Oligomers
WO2014151834A2 (en) 2013-03-15 2014-09-25 Amgen Inc. Methods and compositions relating to anti-ccr7 antigen binding proteins
WO2015147335A1 (ja) * 2014-03-27 2015-10-01 国立大学法人大阪大学 脳マラリアの診断および治療
MA41795A (fr) 2015-03-18 2018-01-23 Sarepta Therapeutics Inc Exclusion d'un exon induite par des composés antisens dans la myostatine
BR112018002877A2 (pt) 2015-08-10 2018-11-06 anticorpos anti-receptor ccr7 humanizados
MA45819A (fr) 2015-10-09 2018-08-15 Sarepta Therapeutics Inc Compositions et méthodes pour traiter la dystrophie musculaire de duchenne et troubles associés
WO2018073248A1 (en) 2016-10-17 2018-04-26 Icm (Institut Du Cerveau Et De La Moelle Épinière) Prognosis of demyelinating diseases patients and treatment thereof
JOP20190187A1 (ar) * 2017-02-03 2019-08-01 Novartis Ag مترافقات عقار جسم مضاد لـ ccr7
KR20210132644A (ko) * 2018-12-18 2021-11-04 캐터펄트 테라퓨틱스 비.브이. 이식편 대 숙주 질환(GvHD)의 예방 또는 치료를 위한 항-CCR7 mAb의 용도
US20230181756A1 (en) * 2020-04-30 2023-06-15 Novartis Ag Ccr7 antibody drug conjugates for treating cancer
CN119390838B (zh) * 2024-05-29 2025-06-10 锐胜科生物医药(上海)有限公司 一种靶向ccr7的纳米抗体及其制备与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7163681B2 (en) * 2000-08-07 2007-01-16 Centocor, Inc. Anti-integrin antibodies, compositions, methods and uses
FR2818747B1 (fr) * 2000-12-26 2003-05-16 Molecular Engines Laboratoires Procede de criblage base sur l'interaction siah-numb
US20020168358A1 (en) * 2001-04-30 2002-11-14 Gladue Ronald P. Treatment of T-cell mediated diseases
DE10248751A1 (de) * 2002-10-18 2004-05-06 Berdel, Wolfgang E., Prof. Dr.med. Dyslokalisationsmoleküle und deren Verwendung
WO2004104574A2 (en) * 2003-05-23 2004-12-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with c-c chemokine receptor type 7 (ccr7)
CA2529058A1 (en) * 2003-06-11 2005-01-13 The University Of Chicago Increased t-cell tumor infiltration by mutant light

Also Published As

Publication number Publication date
CA2614080C (en) 2014-08-26
EP1904102B1 (en) 2009-12-30
EP1904102A1 (en) 2008-04-02
IL188594A (en) 2012-02-29
US20090123483A1 (en) 2009-05-14
BRPI0612632A2 (pt) 2012-01-03
US8066996B2 (en) 2011-11-29
JP5249025B2 (ja) 2013-07-31
JP2008545000A (ja) 2008-12-11
DE602006011466D1 (de) 2010-02-11
WO2007003426A1 (en) 2007-01-11
PT1904102E (pt) 2010-03-29
RU2008104420A (ru) 2009-08-20
AU2006265281C1 (en) 2012-11-15
RU2404808C2 (ru) 2010-11-27
CN101257923A (zh) 2008-09-03
IL188594A0 (en) 2008-04-13
WO2007003216A1 (en) 2007-01-11
ATE453407T1 (de) 2010-01-15
CA2614080A1 (en) 2007-01-11
AU2006265281B2 (en) 2012-03-01
KR20080030655A (ko) 2008-04-04
ES2338919T3 (es) 2010-05-13
AU2006265281A1 (en) 2007-01-11

Similar Documents

Publication Publication Date Title
IL188594A0 (en) Anti-ccr7 receptor antibodies for the treatment of cancer
ZA202308021B (en) Anti-ctla4 antibodies and methods of making and using the same
BR112019024654A2 (pt) proteína de ligação nkg2d, cd16 e ror1 ou ror2
EA201070636A1 (ru) Ингибирование рецептора белка, стимулирующего макрофаги (ron), и способы его лечения
CY1122642T1 (el) Αντι-β7-η1 και anti-ctla-4 αντισωματα για τη θεραπευτικη αγωγη μη μικροκυτταρικου πνευμονικου καρκινου
CR20120105A (es) Proteínas terapéuticas de unión a dll4
EA201170716A1 (ru) Антитела к с-мет
EA200971077A1 (ru) Гетероциклические модуляторы киназы
MX373790B (es) Anticuerpos humanos a ligando de muerte programada 1 (pd-l1).
ECSP14001249A (es) Inmunoenlazadores dirigidos contra el tnf
ECSP14001260A (es) Inmunoligantes biespecificos dirigidos contra tnf e il-17 referencia cruzada a solicitudes relacionadas
CY1112739T1 (el) Αντισωματα και ανοσοσυζευγματα αντι-cd79β και μεθοδοι χρησης
EA201170155A1 (ru) Специфические антагонисты рецептора fgf-r4
EA201100923A1 (ru) Антитела человека против тканевого фактора
MX385545B (es) Anticuerpos humanos para pd-1.
EA201891966A1 (ru) Молекулы, связывающие bcma, и способы их применения
CY1122132T1 (el) Μεθοδοι για τη μειωση των ρυθμων εξαρσης του ασθματος με χρηση μπενραλιζουμαμπης
EA201301180A1 (ru) Основанная на bcma стратификация и терапия пациентов, страдающих множественной миеломой
PH12012502215A1 (en) Anti-fgfr2 antibodies
GT200900002A (es) Anticuerpo antagonista para el tratamiento del cancer
EA201591762A1 (ru) Человеческие антитела к grem1
CY1112798T1 (el) Ενωσεις διαρυλυδαντοϊνης
EA202090387A1 (ru) Белки, связывающие nkg2d, cd16 и flt3
EA201270662A1 (ru) Связывающие элементы для человеческого цитамегаловируса
ATE528319T1 (de) Krebsbehandlung mit anti-il-1-antikörpern