ATE453407T1 - Anti-ccr7-rezeptor-antikörper zur krebsbehandlung - Google Patents
Anti-ccr7-rezeptor-antikörper zur krebsbehandlungInfo
- Publication number
- ATE453407T1 ATE453407T1 AT06776128T AT06776128T ATE453407T1 AT E453407 T1 ATE453407 T1 AT E453407T1 AT 06776128 T AT06776128 T AT 06776128T AT 06776128 T AT06776128 T AT 06776128T AT E453407 T1 ATE453407 T1 AT E453407T1
- Authority
- AT
- Austria
- Prior art keywords
- ccr7 receptor
- cancer treatment
- receptor antibodies
- antibodies
- ccr7
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 2
- 108010017158 CCR7 Receptors Proteins 0.000 abstract 3
- 102000004428 CCR7 Receptors Human genes 0.000 abstract 3
- 210000004881 tumor cell Anatomy 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2005/007371 WO2007003216A1 (en) | 2005-07-06 | 2005-07-06 | Anti-ccr7 receptor antibodies for the treatment of cancer |
| PCT/EP2006/006556 WO2007003426A1 (en) | 2005-07-06 | 2006-07-05 | Anti-ccr7 receptor antibodies for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE453407T1 true ATE453407T1 (de) | 2010-01-15 |
Family
ID=36021798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06776128T ATE453407T1 (de) | 2005-07-06 | 2006-07-05 | Anti-ccr7-rezeptor-antikörper zur krebsbehandlung |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8066996B2 (enExample) |
| EP (1) | EP1904102B1 (enExample) |
| JP (1) | JP5249025B2 (enExample) |
| KR (1) | KR20080030655A (enExample) |
| CN (1) | CN101257923A (enExample) |
| AT (1) | ATE453407T1 (enExample) |
| AU (1) | AU2006265281C1 (enExample) |
| BR (1) | BRPI0612632A2 (enExample) |
| CA (1) | CA2614080C (enExample) |
| DE (1) | DE602006011466D1 (enExample) |
| DK (1) | DK1904102T3 (enExample) |
| ES (1) | ES2338919T3 (enExample) |
| IL (1) | IL188594A (enExample) |
| PT (1) | PT1904102E (enExample) |
| RU (1) | RU2404808C2 (enExample) |
| WO (2) | WO2007003216A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006213686A1 (en) | 2005-02-09 | 2006-08-17 | Avi Bio Pharma, Inc. | Antisense composition and method for treating muscle atrophy |
| EP2285403A2 (en) * | 2008-05-14 | 2011-02-23 | Msm Protein Technologies, Inc. | Human monoclonal antibodies against human chemokine receptor ccr7 |
| US9101559B2 (en) | 2009-05-08 | 2015-08-11 | New York University | Leukemic cell CNS infiltration controlled by notch-induced chemotaxis |
| WO2011040428A1 (ja) * | 2009-09-29 | 2011-04-07 | 学校法人慶應義塾 | 抗腫瘍剤およびそのスクリーニング方法 |
| JP5315495B2 (ja) * | 2010-09-28 | 2013-10-16 | 積水化学工業株式会社 | 抗ヒトｃｃｒ７抗体、ハイブリドーマ、核酸、ベクター、細胞、医薬組成物、並びに、抗体固定化担体 |
| US20130085139A1 (en) | 2011-10-04 | 2013-04-04 | Royal Holloway And Bedford New College | Oligomers |
| WO2014151834A2 (en) | 2013-03-15 | 2014-09-25 | Amgen Inc. | Methods and compositions relating to anti-ccr7 antigen binding proteins |
| WO2015147335A1 (ja) * | 2014-03-27 | 2015-10-01 | 国立大学法人大阪大学 | 脳マラリアの診断および治療 |
| MA41795A (fr) | 2015-03-18 | 2018-01-23 | Sarepta Therapeutics Inc | Exclusion d'un exon induite par des composés antisens dans la myostatine |
| BR112018002877A2 (pt) | 2015-08-10 | 2018-11-06 | anticorpos anti-receptor ccr7 humanizados | |
| MA45819A (fr) | 2015-10-09 | 2018-08-15 | Sarepta Therapeutics Inc | Compositions et méthodes pour traiter la dystrophie musculaire de duchenne et troubles associés |
| WO2018073248A1 (en) | 2016-10-17 | 2018-04-26 | Icm (Institut Du Cerveau Et De La Moelle Épinière) | Prognosis of demyelinating diseases patients and treatment thereof |
| JOP20190187A1 (ar) * | 2017-02-03 | 2019-08-01 | Novartis Ag | مترافقات عقار جسم مضاد لـ ccr7 |
| KR20210132644A (ko) * | 2018-12-18 | 2021-11-04 | 캐터펄트 테라퓨틱스 비.브이. | 이식편 대 숙주 질환(GvHD)의 예방 또는 치료를 위한 항-CCR7 mAb의 용도 |
| US20230181756A1 (en) * | 2020-04-30 | 2023-06-15 | Novartis Ag | Ccr7 antibody drug conjugates for treating cancer |
| CN119390838B (zh) * | 2024-05-29 | 2025-06-10 | 锐胜科生物医药(上海)有限公司 | 一种靶向ccr7的纳米抗体及其制备与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7163681B2 (en) * | 2000-08-07 | 2007-01-16 | Centocor, Inc. | Anti-integrin antibodies, compositions, methods and uses |
| FR2818747B1 (fr) * | 2000-12-26 | 2003-05-16 | Molecular Engines Laboratoires | Procede de criblage base sur l'interaction siah-numb |
| US20020168358A1 (en) * | 2001-04-30 | 2002-11-14 | Gladue Ronald P. | Treatment of T-cell mediated diseases |
| DE10248751A1 (de) * | 2002-10-18 | 2004-05-06 | Berdel, Wolfgang E., Prof. Dr.med. | Dyslokalisationsmoleküle und deren Verwendung |
| WO2004104574A2 (en) * | 2003-05-23 | 2004-12-02 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with c-c chemokine receptor type 7 (ccr7) |
| CA2529058A1 (en) * | 2003-06-11 | 2005-01-13 | The University Of Chicago | Increased t-cell tumor infiltration by mutant light |
-
2005
- 2005-07-06 WO PCT/EP2005/007371 patent/WO2007003216A1/en not_active Ceased
-
2006
- 2006-07-05 US US11/994,833 patent/US8066996B2/en active Active
- 2006-07-05 AT AT06776128T patent/ATE453407T1/de active
- 2006-07-05 EP EP06776128A patent/EP1904102B1/en active Active
- 2006-07-05 DE DE602006011466T patent/DE602006011466D1/de active Active
- 2006-07-05 BR BRPI0612632-4A patent/BRPI0612632A2/pt not_active Application Discontinuation
- 2006-07-05 DK DK06776128.8T patent/DK1904102T3/da active
- 2006-07-05 WO PCT/EP2006/006556 patent/WO2007003426A1/en not_active Ceased
- 2006-07-05 KR KR1020087003130A patent/KR20080030655A/ko not_active Ceased
- 2006-07-05 CA CA2614080A patent/CA2614080C/en active Active
- 2006-07-05 AU AU2006265281A patent/AU2006265281C1/en active Active
- 2006-07-05 RU RU2008104420/10A patent/RU2404808C2/ru active
- 2006-07-05 ES ES06776128T patent/ES2338919T3/es active Active
- 2006-07-05 PT PT06776128T patent/PT1904102E/pt unknown
- 2006-07-05 CN CNA2006800323035A patent/CN101257923A/zh active Pending
- 2006-07-05 JP JP2008519857A patent/JP5249025B2/ja active Active
-
2008
- 2008-01-03 IL IL188594A patent/IL188594A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2614080C (en) | 2014-08-26 |
| EP1904102B1 (en) | 2009-12-30 |
| EP1904102A1 (en) | 2008-04-02 |
| IL188594A (en) | 2012-02-29 |
| US20090123483A1 (en) | 2009-05-14 |
| BRPI0612632A2 (pt) | 2012-01-03 |
| US8066996B2 (en) | 2011-11-29 |
| JP5249025B2 (ja) | 2013-07-31 |
| JP2008545000A (ja) | 2008-12-11 |
| DE602006011466D1 (de) | 2010-02-11 |
| WO2007003426A1 (en) | 2007-01-11 |
| PT1904102E (pt) | 2010-03-29 |
| RU2008104420A (ru) | 2009-08-20 |
| DK1904102T3 (da) | 2010-04-19 |
| AU2006265281C1 (en) | 2012-11-15 |
| RU2404808C2 (ru) | 2010-11-27 |
| CN101257923A (zh) | 2008-09-03 |
| IL188594A0 (en) | 2008-04-13 |
| WO2007003216A1 (en) | 2007-01-11 |
| CA2614080A1 (en) | 2007-01-11 |
| AU2006265281B2 (en) | 2012-03-01 |
| KR20080030655A (ko) | 2008-04-04 |
| ES2338919T3 (es) | 2010-05-13 |
| AU2006265281A1 (en) | 2007-01-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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