JP2008543853A5 - - Google Patents
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- JP2008543853A5 JP2008543853A5 JP2008517022A JP2008517022A JP2008543853A5 JP 2008543853 A5 JP2008543853 A5 JP 2008543853A5 JP 2008517022 A JP2008517022 A JP 2008517022A JP 2008517022 A JP2008517022 A JP 2008517022A JP 2008543853 A5 JP2008543853 A5 JP 2008543853A5
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- JP
- Japan
- Prior art keywords
- compound
- formula
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- Prior art date
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- 150000001875 compounds Chemical class 0.000 claims 14
- 238000000034 method Methods 0.000 claims 14
- 238000012423 maintenance Methods 0.000 claims 9
- JALHGCPDPSNJNY-UHFFFAOYSA-N [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4h-thieno[3,2-c]pyridin-2-yl] acetate;hydron;chloride Chemical compound Cl.C1CC=2SC(OC(=O)C)=CC=2CN1C(C=1C(=CC=CC=1)F)C(=O)C1CC1 JALHGCPDPSNJNY-UHFFFAOYSA-N 0.000 claims 5
- 229960004947 prasugrel hydrochloride Drugs 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 4
- DTGLZDAWLRGWQN-UHFFFAOYSA-N prasugrel Chemical compound C1CC=2SC(OC(=O)C)=CC=2CN1C(C=1C(=CC=CC=1)F)C(=O)C1CC1 DTGLZDAWLRGWQN-UHFFFAOYSA-N 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 3
- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 claims 2
- 208000004476 Acute Coronary Syndrome Diseases 0.000 claims 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims 2
- 239000005465 B01AC22 - Prasugrel Substances 0.000 claims 2
- 208000005189 Embolism Diseases 0.000 claims 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 2
- 208000001435 Thromboembolism Diseases 0.000 claims 2
- 208000007536 Thrombosis Diseases 0.000 claims 2
- 229960001138 acetylsalicylic acid Drugs 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 229960004197 prasugrel Drugs 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 208000019553 vascular disease Diseases 0.000 claims 2
- 238000013146 percutaneous coronary intervention Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69174005P | 2005-06-17 | 2005-06-17 | |
| PCT/US2006/023006 WO2006138317A2 (en) | 2005-06-17 | 2006-06-13 | Dosage regimen for prasugrel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008543853A JP2008543853A (ja) | 2008-12-04 |
| JP2008543853A5 true JP2008543853A5 (enExample) | 2009-07-30 |
Family
ID=37571073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008517022A Pending JP2008543853A (ja) | 2005-06-17 | 2006-06-13 | プラスグレルのための薬剤投与計画 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20090156632A1 (enExample) |
| EP (1) | EP1893205A4 (enExample) |
| JP (1) | JP2008543853A (enExample) |
| KR (1) | KR20080016647A (enExample) |
| CN (1) | CN101198329A (enExample) |
| AU (1) | AU2006259538A1 (enExample) |
| BR (1) | BRPI0612624A2 (enExample) |
| CA (1) | CA2612315A1 (enExample) |
| EA (1) | EA200800075A1 (enExample) |
| EC (1) | ECSP078014A (enExample) |
| GT (1) | GT200600263A (enExample) |
| IL (1) | IL187486A0 (enExample) |
| MA (1) | MA29722B1 (enExample) |
| MX (1) | MX2007015430A (enExample) |
| NO (1) | NO20080244L (enExample) |
| TN (1) | TNSN07474A1 (enExample) |
| WO (1) | WO2006138317A2 (enExample) |
| ZA (1) | ZA200710769B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2008072532A1 (ja) * | 2006-12-07 | 2010-03-25 | 第一三共株式会社 | 貯蔵安定性が改善された医薬組成物 |
| TWI482641B (zh) | 2006-12-07 | 2015-05-01 | Daiichi Sankyo Co Ltd | 含有低取代度羥丙基纖維素之醫藥組成物 |
| CN101686681B (zh) | 2007-04-27 | 2015-04-01 | 锡德克斯药物公司 | 包含氯吡格雷和磺基烷基醚环糊精的制剂和其使用方法 |
| PL3100728T3 (pl) | 2009-05-13 | 2020-05-18 | Cydex Pharmaceuticals, Inc. | Kompozycje farmaceutyczne zawierające prasugrel i pochodne cyklodekstryny oraz sposoby ich wytwarzania i zastosowania |
| US10376532B2 (en) * | 2009-11-11 | 2019-08-13 | Chiesi Farmaceutici, S.P.A. | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
| TR201006802A1 (tr) * | 2010-08-17 | 2012-03-21 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Prasugrelin oral yolla dağılan formülasyonları. |
| EP2409685A3 (en) | 2010-07-19 | 2012-02-01 | Sanovel Ilac Sanayi ve Ticaret A.S. | Orally-disintegrating formulations of prasugrel |
| EP3106151A1 (en) | 2015-06-19 | 2016-12-21 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical compositions of prasugrel hydrobromide |
| WO2018167447A1 (en) * | 2017-03-14 | 2018-09-20 | University Of Sheffield | Low dose aspirin (1-50 mg) together with antiplatelets such as ticagrelor of anticoagulants |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI101150B (fi) * | 1991-09-09 | 1998-04-30 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi |
| US6509348B1 (en) * | 1998-11-03 | 2003-01-21 | Bristol-Myers Squibb Company | Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination |
| US6544981B2 (en) * | 2000-06-09 | 2003-04-08 | Bristol-Myers Squibb Company | Lactam inhibitors of factor Xa and method |
| KR20080021152A (ko) * | 2000-07-06 | 2008-03-06 | 다이이찌 산쿄 가부시키가이샤 | 히드로피리딘 유도체 산부가염 |
| JP4001199B2 (ja) * | 2000-07-06 | 2007-10-31 | 第一三共株式会社 | ヒドロピリジン誘導体酸付加塩 |
| JP4874482B2 (ja) * | 2000-12-25 | 2012-02-15 | 第一三共株式会社 | アスピリンを含有する医薬組成物 |
| CZ297570B6 (cs) * | 2000-12-25 | 2007-02-07 | Sankyo Company, Limited | Farmaceutický prípravek obsahující 2-acetoxypyridinový derivát a aspirin, které spolu pusobí v synergickém úcinku, kit jej obsahující a pouzití |
| EP1660183A2 (en) * | 2003-05-05 | 2006-05-31 | Eli Lilly and Company | Treating cardiovascular diseases with a compound of formula 1 (cs 747 - prasugrel; rn 150322-43-4) |
-
2006
- 2006-06-13 KR KR1020077029366A patent/KR20080016647A/ko not_active Ceased
- 2006-06-13 US US11/916,817 patent/US20090156632A1/en not_active Abandoned
- 2006-06-13 CN CNA2006800217943A patent/CN101198329A/zh active Pending
- 2006-06-13 CA CA002612315A patent/CA2612315A1/en not_active Abandoned
- 2006-06-13 AU AU2006259538A patent/AU2006259538A1/en not_active Abandoned
- 2006-06-13 WO PCT/US2006/023006 patent/WO2006138317A2/en not_active Ceased
- 2006-06-13 EP EP06773053A patent/EP1893205A4/en not_active Withdrawn
- 2006-06-13 EA EA200800075A patent/EA200800075A1/ru unknown
- 2006-06-13 JP JP2008517022A patent/JP2008543853A/ja active Pending
- 2006-06-13 BR BRPI0612624A patent/BRPI0612624A2/pt not_active IP Right Cessation
- 2006-06-13 MX MX2007015430A patent/MX2007015430A/es unknown
- 2006-06-16 GT GT200600263A patent/GT200600263A/es unknown
-
2007
- 2007-11-19 IL IL187486A patent/IL187486A0/en unknown
- 2007-12-11 ZA ZA200710769A patent/ZA200710769B/xx unknown
- 2007-12-14 EC EC2007008014A patent/ECSP078014A/es unknown
- 2007-12-14 TN TNP2007000474A patent/TNSN07474A1/en unknown
-
2008
- 2008-01-14 NO NO20080244A patent/NO20080244L/no not_active Application Discontinuation
- 2008-01-16 MA MA30577A patent/MA29722B1/fr unknown
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