JP2008543853A - プラスグレルのための薬剤投与計画 - Google Patents

プラスグレルのための薬剤投与計画 Download PDF

Info

Publication number
JP2008543853A
JP2008543853A JP2008517022A JP2008517022A JP2008543853A JP 2008543853 A JP2008543853 A JP 2008543853A JP 2008517022 A JP2008517022 A JP 2008517022A JP 2008517022 A JP2008517022 A JP 2008517022A JP 2008543853 A JP2008543853 A JP 2008543853A
Authority
JP
Japan
Prior art keywords
administration
prasugrel
compound
formula
equivalent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008517022A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008543853A5 (enExample
Inventor
ジョン・トーマス・ブラント
ナギー・アルフォンス・ファリッド
ジョゼフ・アンソニー・ジャクボースキー
クリストファー・デイビッド・ペイン
ゴビンダ・ジャヤナト・ウィーラコディ
ケネス・ジョン・ウィンターズ
Original Assignee
イーライ リリー アンド カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by イーライ リリー アンド カンパニー filed Critical イーライ リリー アンド カンパニー
Publication of JP2008543853A publication Critical patent/JP2008543853A/ja
Publication of JP2008543853A5 publication Critical patent/JP2008543853A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4743—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2008517022A 2005-06-17 2006-06-13 プラスグレルのための薬剤投与計画 Pending JP2008543853A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69174005P 2005-06-17 2005-06-17
PCT/US2006/023006 WO2006138317A2 (en) 2005-06-17 2006-06-13 Dosage regimen for prasugrel

Publications (2)

Publication Number Publication Date
JP2008543853A true JP2008543853A (ja) 2008-12-04
JP2008543853A5 JP2008543853A5 (enExample) 2009-07-30

Family

ID=37571073

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008517022A Pending JP2008543853A (ja) 2005-06-17 2006-06-13 プラスグレルのための薬剤投与計画

Country Status (18)

Country Link
US (1) US20090156632A1 (enExample)
EP (1) EP1893205A4 (enExample)
JP (1) JP2008543853A (enExample)
KR (1) KR20080016647A (enExample)
CN (1) CN101198329A (enExample)
AU (1) AU2006259538A1 (enExample)
BR (1) BRPI0612624A2 (enExample)
CA (1) CA2612315A1 (enExample)
EA (1) EA200800075A1 (enExample)
EC (1) ECSP078014A (enExample)
GT (1) GT200600263A (enExample)
IL (1) IL187486A0 (enExample)
MA (1) MA29722B1 (enExample)
MX (1) MX2007015430A (enExample)
NO (1) NO20080244L (enExample)
TN (1) TNSN07474A1 (enExample)
WO (1) WO2006138317A2 (enExample)
ZA (1) ZA200710769B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2672154C (en) * 2006-12-07 2014-11-18 Daiichi Sankyo Company, Limited Pharmaceutical composition having improved storage stability
WO2008072535A1 (ja) 2006-12-07 2008-06-19 Daiichi Sankyo Company, Limited 低置換度ヒドロキシプロピルセルロースを含有する医薬組成物
CA2685331C (en) 2007-04-27 2016-07-05 Cydex Pharmaceuticals, Inc. Formulations containing clopidogrel and sulfoalkyl ether cyclodextrin and methods of use
KR101912709B1 (ko) 2009-05-13 2018-10-30 사이덱스 파마슈티칼스, 인크. 프라수그렐 및 사이클로덱스트린 유도체를 포함하는 약학 조성물 및 그의 제조 및 사용 방법
US10376532B2 (en) * 2009-11-11 2019-08-13 Chiesi Farmaceutici, S.P.A. Methods of treating, reducing the incidence of, and/or preventing ischemic events
TR201006802A1 (tr) * 2010-08-17 2012-03-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Prasugrelin oral yolla dağılan formülasyonları.
EP2409685A3 (en) 2010-07-19 2012-02-01 Sanovel Ilac Sanayi ve Ticaret A.S. Orally-disintegrating formulations of prasugrel
WO2016203018A1 (en) 2015-06-19 2016-12-22 Sanovel Ilac Sanayi Ve Ticaret A.S. Pharmaceutical compositions of prasugrel hydrobromide
WO2018167447A1 (en) * 2017-03-14 2018-09-20 University Of Sheffield Low dose aspirin (1-50 mg) together with antiplatelets such as ticagrelor of anticoagulants

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0641139A (ja) * 1991-09-09 1994-02-15 Sankyo Co Ltd ヒドロピリジン誘導体
US20020025957A1 (en) * 2000-06-09 2002-02-28 Stein Philip D. Lactam inhibitors of factor Xa and method
JP2002145883A (ja) * 2000-07-06 2002-05-22 Sankyo Co Ltd ヒドロピリジン誘導体酸付加塩
JP2002255814A (ja) * 2000-12-25 2002-09-11 Sankyo Co Ltd アスピリンを含有する医薬組成物
US6509348B1 (en) * 1998-11-03 2003-01-21 Bristol-Myers Squibb Company Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination
WO2004098713A2 (en) * 2003-05-05 2004-11-18 Eli Lilly And Company Treating cardiovascular diseases with a compound of formula (i) (cs 747 - prasugrel; rn 150322-43-4)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2703697C (en) * 2000-07-06 2012-09-04 Daiichi Sankyo Company, Limited Acid addition salts of hydropyridine derivatives
CN100341506C (zh) * 2000-12-25 2007-10-10 三共株式会社 含有阿斯匹林的药用组合物

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0641139A (ja) * 1991-09-09 1994-02-15 Sankyo Co Ltd ヒドロピリジン誘導体
US6509348B1 (en) * 1998-11-03 2003-01-21 Bristol-Myers Squibb Company Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination
US20020025957A1 (en) * 2000-06-09 2002-02-28 Stein Philip D. Lactam inhibitors of factor Xa and method
JP2002145883A (ja) * 2000-07-06 2002-05-22 Sankyo Co Ltd ヒドロピリジン誘導体酸付加塩
JP2002255814A (ja) * 2000-12-25 2002-09-11 Sankyo Co Ltd アスピリンを含有する医薬組成物
WO2004098713A2 (en) * 2003-05-05 2004-11-18 Eli Lilly And Company Treating cardiovascular diseases with a compound of formula (i) (cs 747 - prasugrel; rn 150322-43-4)

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN6008019294; ＳＵＧＩＤＡＣＨＩ，　Ａ．　ＥＴ　ＡＬ．: '"Ｔｈｅ　ｉｎ　ｖｉｖｏ　ｐｈａｒｍａｃｏｌｏｇｉｃａｌ　ｐｒｏｆｉｌｅ　ｏｆ　ＣＳ-７４７，　ａ　ｎｏｖｅｌ　ａｎｔｉｐｌａｔｅｌｅｔ　ａｇｅｎｔ　ｗｉｔｈ　ｐｌａｔｅｌｅｔ　ＡＤＰ　ｒｅｃｅｐｔｏ' ＢＲＩＴＩＳＨ　ＪＯＵＲＮＡＬ　ＯＦ　ＰＨＡＲＭＡＣＯＬＯＧＹ Ｖｏｌ．１２９，　Ｎｏ．７, 200004, ｐｐ．１４３９-１４４６ *
JPN6012024565; 「今日の治療指針２００４年版（Ｖｏｌｕｍｅ　４６）」 , 20040101, ２４４-２４５頁, 株式会社医学書院 *
JPN6012024566; 「今日の治療指針２００２年版〔ポケット版〕」 , 20020101, ２２８-２２９頁, 株式会社医学書院 *
JPN6012024567; ＷＩＶＩＯＴＴ，Ｓ．，ＥＴ　ＡＬ．: '"Ｒａｎｄｏｍｉｚｅｄ　ｃｏｍｐａｒｉｓｏｎ　ｏｆ　ｐｒａｓｕｇｒｅｌ　（ＣＳ-７４７，　ＬＹ６４０３１５），　ａ　ｎｏｖｅｌ　ｔｈｉｅｎｏｐｙｒｉｄｉｎｅ　Ｐ２Ｙ１２　ａｎｔａｇｏｎｉｓｔ，　ｗｉｔ' ＣＩＲＣＵＬＡＴＩＯＮ ＶＯＬ．１１１，ＮＯ．２５, 20050628, ＰＰ．３３６６-３３７３ *

Also Published As

Publication number Publication date
NO20080244L (no) 2008-01-14
KR20080016647A (ko) 2008-02-21
BRPI0612624A2 (pt) 2016-11-29
US20090156632A1 (en) 2009-06-18
ECSP078014A (es) 2008-01-23
WO2006138317A2 (en) 2006-12-28
EP1893205A2 (en) 2008-03-05
GT200600263A (es) 2007-02-23
CN101198329A (zh) 2008-06-11
AU2006259538A1 (en) 2006-12-28
MX2007015430A (es) 2008-02-21
EP1893205A4 (en) 2010-06-30
MA29722B1 (fr) 2008-09-01
WO2006138317A3 (en) 2007-05-03
IL187486A0 (en) 2008-06-05
TNSN07474A1 (en) 2009-03-17
CA2612315A1 (en) 2006-12-28
EA200800075A1 (ru) 2008-04-28
ZA200710769B (en) 2009-09-30

Similar Documents

Publication Publication Date Title
US8569325B2 (en) Method of treatment with coadministration of aspirin and prasugrel
KR20160147044A (ko) 과다운동성 운동 장애의 치료를 위한 vmat2 억제제
US20250099466A1 (en) Milvexian for prevention and treatment of thromboembolic disorders
CN102149377A (zh) 决奈达隆在制备用于预防中风或短暂性缺血发作的药物中的用途
JP2008543853A (ja) プラスグレルのための薬剤投与計画
PL206069B1 (pl) Tabletka dwuwarstwowa zawierająca cetyryzynę i pseudoefedrynę
CA2910395A1 (en) Vanoxerine for self-administration for terminating acute episodes of cardiac arrhythmia in mammals
EP1727547A1 (en) Compounds for the sustained reduction of body weight
US9446038B2 (en) Method and composition for treating a serotonin receptor-mediated condition
JP2019524682A (ja) 抗うつ作用の速い発現のためのボルチオキセチン投与計画
US20160051542A1 (en) Methods of administration of single doses of vanoxerine to terminate acute episodes of cardiac arrhythmia
WO2011052500A1 (ja) ワックス安定製剤
WO2011052499A1 (ja) 貯蔵安定性が改善された医薬組成物
TWI334349B (en) Pain threshold reduction depressant
EA042135B1 (ru) Таблетка деферипрона с отсроченным высвобождением и способ ее изготовления
HK40045857A (en) Method of treating or prevention of atherothrombotic events in patients with history of myocardial infarction
HK1117386A (en) Method of treating liver cancer
HK1056118B (en) Medicinal compositions containing aspirin

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090612

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090612

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120515

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20121016