JP2008542281A5 - - Google Patents
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- Publication number
- JP2008542281A5 JP2008542281A5 JP2008513672A JP2008513672A JP2008542281A5 JP 2008542281 A5 JP2008542281 A5 JP 2008542281A5 JP 2008513672 A JP2008513672 A JP 2008513672A JP 2008513672 A JP2008513672 A JP 2008513672A JP 2008542281 A5 JP2008542281 A5 JP 2008542281A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- ylmethyl
- phenyl
- piperidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68446605P | 2005-05-25 | 2005-05-25 | |
| US68447805P | 2005-05-25 | 2005-05-25 | |
| US60/684,478 | 2005-05-25 | ||
| US60/684,466 | 2005-05-25 | ||
| US74841505P | 2005-12-08 | 2005-12-08 | |
| US60/748,415 | 2005-12-08 | ||
| PCT/US2006/020085 WO2006127815A2 (en) | 2005-05-25 | 2006-05-24 | Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012162692A Division JP2012197322A (ja) | 2005-05-25 | 2012-07-23 | ５−ｈｔ４レセプターアゴニストとしてのベンズイミダゾール−カルボキサミド化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008542281A JP2008542281A (ja) | 2008-11-27 |
| JP2008542281A5 true JP2008542281A5 (enExample) | 2009-06-18 |
| JP5072111B2 JP5072111B2 (ja) | 2012-11-14 |
Family
ID=37452788
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008513672A Expired - Fee Related JP5072111B2 (ja) | 2005-05-25 | 2006-05-24 | ５−ｈｔ４レセプターアゴニストとしてのベンズイミダゾール−カルボキサミド化合物 |
| JP2012162692A Withdrawn JP2012197322A (ja) | 2005-05-25 | 2012-07-23 | ５−ｈｔ４レセプターアゴニストとしてのベンズイミダゾール−カルボキサミド化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012162692A Withdrawn JP2012197322A (ja) | 2005-05-25 | 2012-07-23 | ５−ｈｔ４レセプターアゴニストとしてのベンズイミダゾール−カルボキサミド化合物 |
Country Status (26)
| Country | Link |
|---|---|
| US (10) | US7759363B2 (enExample) |
| EP (1) | EP1899324B1 (enExample) |
| JP (2) | JP5072111B2 (enExample) |
| KR (1) | KR101333280B1 (enExample) |
| AR (1) | AR057327A1 (enExample) |
| AT (1) | ATE535523T1 (enExample) |
| AU (1) | AU2006250009B2 (enExample) |
| BR (1) | BRPI0611202C1 (enExample) |
| CA (1) | CA2607280C (enExample) |
| CY (1) | CY1112366T1 (enExample) |
| DK (1) | DK1899324T3 (enExample) |
| EA (1) | EA013240B1 (enExample) |
| ES (1) | ES2376115T3 (enExample) |
| HR (1) | HRP20120108T2 (enExample) |
| IL (1) | IL186883A (enExample) |
| MA (1) | MA29541B1 (enExample) |
| MX (1) | MX2007014762A (enExample) |
| MY (1) | MY147756A (enExample) |
| NO (1) | NO339658B1 (enExample) |
| NZ (1) | NZ563068A (enExample) |
| PE (1) | PE20061446A1 (enExample) |
| PL (1) | PL1899324T3 (enExample) |
| PT (1) | PT1899324E (enExample) |
| SI (1) | SI1899324T1 (enExample) |
| TW (1) | TWI388555B (enExample) |
| WO (1) | WO2006127815A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1664036T3 (pl) * | 2003-09-03 | 2012-04-30 | Pfizer | Związki benzimidazolonu wykazujące działanie agonistyczne względem receptora 5-ht4 |
| US8309575B2 (en) | 2004-04-07 | 2012-11-13 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
| MY147756A (en) * | 2005-05-25 | 2013-01-15 | Theravance Inc | Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists |
| US7256294B2 (en) * | 2005-05-25 | 2007-08-14 | Theravance, Inc. | Crystalline form of a benzimidazole-carboxamide medicinal compound |
| US8349852B2 (en) | 2009-01-13 | 2013-01-08 | Novartis Ag | Quinazolinone derivatives useful as vanilloid antagonists |
| WO2010111058A1 (en) * | 2009-03-23 | 2010-09-30 | Merck Sharp & Dohme Corp. | P2x3, receptor antagonists for treatment of pain |
| LT2419104T (lt) * | 2009-04-13 | 2018-02-12 | Theravance Biopharma R&D Ip, Llc | 5-ht4 receptoriaus agonistų ir acetilcholinesterazės inhibitorių deriniai, skirti pažinimo sutrikimų gydymui |
| CN102762572A (zh) | 2010-02-01 | 2012-10-31 | 诺瓦提斯公司 | 作为CRF-1受体拮抗剂的吡唑并[5,1b]*唑衍生物 |
| AR080056A1 (es) | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de ciclohexil-amida como antagonistas de los receptores de crf |
| EP2531490B1 (en) | 2010-02-02 | 2014-10-15 | Novartis AG | Cyclohexyl amide derivatives as crf receptor antagonists |
| US9676703B2 (en) | 2013-08-09 | 2017-06-13 | Santen Pharmaceutical Co., Ltd. | Production method for 3,3-dimethyl-3,4-dihydro-1H-quinoxalin-2-one derivative and intermediate for said production method |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO984B1 (en) * | 1977-10-11 | 1979-12-01 | بيتشام غروب ليمتد | A dry pharmaceutical compound with a suitable dosage unit for oral administration |
| ES2109190B1 (es) | 1996-03-22 | 1998-07-01 | Univ Madrid Complutense | Nuevos derivados de bencimidazol con afinidad por los receptores serotoninergicos 5-ht /5-ht |
| JPH111472A (ja) | 1996-04-30 | 1999-01-06 | Dainippon Pharmaceut Co Ltd | ベンズアミド誘導体及びそれを含有する医薬組成物 |
| KR20010043032A (ko) | 1998-04-28 | 2001-05-25 | 도모따께 다께시 | 1-[(1-치환-4-피페리디닐)메틸]-4-피페리딘 유도체, 그의제조방법, 그것을 함유하는의약조성물 및 이 화합물의중간체 |
| TR200101239T2 (tr) | 1998-11-03 | 2001-11-21 | Basf Aktiengesellschaft | İkameli-2-fenilbenzimidazoller, üretimleri ve kullanımları |
| US6353005B1 (en) * | 1999-03-02 | 2002-03-05 | Sepracor, Inc. | Method and compositions using (+) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist |
| ES2154605B1 (es) | 1999-09-14 | 2001-11-16 | Univ Madrid Complutense | Nuevos derivados mixtos de bencimidazol-arilpiperazina con afinidad por los receptores serotoninergicos 5-ht1a y 5-ht3 |
| JP2001122784A (ja) | 1999-10-27 | 2001-05-08 | Dainippon Pharmaceut Co Ltd | １−［（１−置換−４−ピペリジニル）メチル］−４−ピペリジン誘導体からなる医薬 |
| US6552046B2 (en) * | 2000-06-07 | 2003-04-22 | Aryx Therapeutics | Materials and methods for the treatment of gastroesophageal reflux disease |
| US6696468B2 (en) | 2002-05-16 | 2004-02-24 | Dainippon Pharmaceutical Co., Ltd. | (s)-4-amino-5-chloro-2-methoxy-n-[1-[1-(2-tetrahydrofuryl-carbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamide, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor |
| ES2285227T3 (es) | 2002-08-05 | 2007-11-16 | Eli Lilly And Company | Arilbenzodiazepinas sustituidas con piperazina. |
| WO2004026868A1 (en) * | 2002-09-20 | 2004-04-01 | Pfizer Japan Inc. | N-substituted piperidinyl-imidazopyridine compounds as 5-ht4 receptor modulators |
| JP2004277319A (ja) | 2003-03-14 | 2004-10-07 | Dainippon Pharmaceut Co Ltd | １−（４−ピペリジニルメチル）ピペリジニルアミド誘導体およびそれを含有する医薬組成物 |
| JP2004277318A (ja) * | 2003-03-14 | 2004-10-07 | Dainippon Pharmaceut Co Ltd | １−（１−置換カルボニル−４−ピペリジニルメチル）ピペリジン誘導体およびそれを含有する医薬組成物 |
| JP2004277320A (ja) | 2003-03-14 | 2004-10-07 | Dainippon Pharmaceut Co Ltd | １，４−ジ置換ピペリジン誘導体およびそれを含有する医薬組成物 |
| PL1664036T3 (pl) | 2003-09-03 | 2012-04-30 | Pfizer | Związki benzimidazolonu wykazujące działanie agonistyczne względem receptora 5-ht4 |
| MY147756A (en) | 2005-05-25 | 2013-01-15 | Theravance Inc | Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists |
| US7256294B2 (en) | 2005-05-25 | 2007-08-14 | Theravance, Inc. | Crystalline form of a benzimidazole-carboxamide medicinal compound |
-
2006
- 2006-05-17 MY MYPI20062263A patent/MY147756A/en unknown
- 2006-05-22 TW TW095118168A patent/TWI388555B/zh not_active IP Right Cessation
- 2006-05-23 PE PE2006000543A patent/PE20061446A1/es active IP Right Grant
- 2006-05-24 BR BRPI0611202A patent/BRPI0611202C1/pt not_active IP Right Cessation
- 2006-05-24 SI SI200631257T patent/SI1899324T1/sl unknown
- 2006-05-24 US US11/439,671 patent/US7759363B2/en active Active
- 2006-05-24 AR ARP060102166A patent/AR057327A1/es active IP Right Grant
- 2006-05-24 KR KR1020077030010A patent/KR101333280B1/ko not_active Expired - Fee Related
- 2006-05-24 MX MX2007014762A patent/MX2007014762A/es active IP Right Grant
- 2006-05-24 PT PT06760341T patent/PT1899324E/pt unknown
- 2006-05-24 AT AT06760341T patent/ATE535523T1/de active
- 2006-05-24 DK DK06760341.5T patent/DK1899324T3/da active
- 2006-05-24 HR HR20120108T patent/HRP20120108T2/hr unknown
- 2006-05-24 EA EA200702612A patent/EA013240B1/ru not_active IP Right Cessation
- 2006-05-24 PL PL06760341T patent/PL1899324T3/pl unknown
- 2006-05-24 NZ NZ563068A patent/NZ563068A/en not_active IP Right Cessation
- 2006-05-24 AU AU2006250009A patent/AU2006250009B2/en not_active Ceased
- 2006-05-24 WO PCT/US2006/020085 patent/WO2006127815A2/en not_active Ceased
- 2006-05-24 CA CA2607280A patent/CA2607280C/en not_active Expired - Lifetime
- 2006-05-24 ES ES06760341T patent/ES2376115T3/es not_active Expired - Lifetime
- 2006-05-24 US US11/920,817 patent/US8143279B2/en not_active Expired - Fee Related
- 2006-05-24 EP EP06760341A patent/EP1899324B1/en not_active Expired - Lifetime
- 2006-05-24 JP JP2008513672A patent/JP5072111B2/ja not_active Expired - Fee Related
-
2007
- 2007-10-24 IL IL186883A patent/IL186883A/en active IP Right Grant
- 2007-12-10 MA MA30466A patent/MA29541B1/fr unknown
- 2007-12-17 NO NO20076481A patent/NO339658B1/no not_active IP Right Cessation
-
2010
- 2010-06-09 US US12/796,902 patent/US8377964B2/en not_active Expired - Fee Related
-
2012
- 2012-02-17 CY CY20121100168T patent/CY1112366T1/el unknown
- 2012-07-23 JP JP2012162692A patent/JP2012197322A/ja not_active Withdrawn
-
2013
- 2013-01-16 US US13/742,783 patent/US20130273568A1/en not_active Abandoned
-
2014
- 2014-09-17 US US14/488,520 patent/US9428489B2/en not_active Expired - Fee Related
-
2016
- 2016-07-28 US US15/221,841 patent/US9975877B2/en not_active Expired - Fee Related
-
2018
- 2018-04-19 US US15/956,958 patent/US10233172B2/en not_active Expired - Lifetime
-
2019
- 2019-01-29 US US16/260,984 patent/US10696656B2/en not_active Expired - Fee Related
-
2020
- 2020-05-22 US US16/881,209 patent/US11254655B2/en not_active Expired - Fee Related
-
2022
- 2022-01-12 US US17/573,814 patent/US20220274957A1/en not_active Abandoned
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