JP2008541768A5 - - Google Patents
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- JP2008541768A5 JP2008541768A5 JP2008514924A JP2008514924A JP2008541768A5 JP 2008541768 A5 JP2008541768 A5 JP 2008541768A5 JP 2008514924 A JP2008514924 A JP 2008514924A JP 2008514924 A JP2008514924 A JP 2008514924A JP 2008541768 A5 JP2008541768 A5 JP 2008541768A5
- Authority
- JP
- Japan
- Prior art keywords
- recombinant retrovirus
- antibody
- cell
- fusion molecule
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 230000004927 fusion Effects 0.000 claims description 16
- 108090000623 proteins and genes Proteins 0.000 claims description 10
- 241000700605 Viruses Species 0.000 claims description 6
- 206010028980 Neoplasm Diseases 0.000 claims description 4
- 102000004169 proteins and genes Human genes 0.000 claims description 4
- 239000013598 vector Substances 0.000 claims description 4
- 238000001727 in vivo Methods 0.000 claims description 3
- 201000011510 cancer Diseases 0.000 claims description 2
- 239000012528 membrane Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 25
- 241001430294 unidentified retrovirus Species 0.000 claims 17
- 230000009870 specific binding Effects 0.000 claims 8
- 108060003951 Immunoglobulin Proteins 0.000 claims 4
- 102000018358 immunoglobulin Human genes 0.000 claims 4
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 230000003612 virological effect Effects 0.000 claims 4
- 102000003886 Glycoproteins Human genes 0.000 claims 3
- 108090000288 Glycoproteins Proteins 0.000 claims 3
- 238000004806 packaging method and process Methods 0.000 claims 3
- 241000713666 Lentivirus Species 0.000 claims 2
- 230000027455 binding Effects 0.000 claims 2
- 241000178568 Aura virus Species 0.000 claims 1
- 241000724653 Borna disease virus Species 0.000 claims 1
- 241000725619 Dengue virus Species 0.000 claims 1
- 206010066919 Epidemic polyarthritis Diseases 0.000 claims 1
- 108700028146 Genetic Enhancer Elements Proteins 0.000 claims 1
- 101710154606 Hemagglutinin Proteins 0.000 claims 1
- 241000700721 Hepatitis B virus Species 0.000 claims 1
- 206010023927 Lassa fever Diseases 0.000 claims 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 1
- 101710176177 Protein A56 Proteins 0.000 claims 1
- 241000711798 Rabies lyssavirus Species 0.000 claims 1
- 108700008625 Reporter Genes Proteins 0.000 claims 1
- 241000710942 Ross River virus Species 0.000 claims 1
- 241000315672 SARS coronavirus Species 0.000 claims 1
- 241000710961 Semliki Forest virus Species 0.000 claims 1
- 108020004459 Small interfering RNA Proteins 0.000 claims 1
- 241000710771 Tick-borne encephalitis virus Species 0.000 claims 1
- 239000000185 hemagglutinin Substances 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 description 6
- 108091007433 antigens Proteins 0.000 description 3
- 230000035800 maturation Effects 0.000 description 3
- 230000008685 targeting Effects 0.000 description 3
- 102100033486 Lymphocyte antigen 75 Human genes 0.000 description 2
- 101710157884 Lymphocyte antigen 75 Proteins 0.000 description 2
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108010029697 CD40 Ligand Proteins 0.000 description 1
- 230000005867 T cell response Effects 0.000 description 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 description 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 description 1
- 230000030741 antigen processing and presentation Effects 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 230000012202 endocytosis Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 210000003563 lymphoid tissue Anatomy 0.000 description 1
- 201000001441 melanoma Diseases 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68621505P | 2005-06-01 | 2005-06-01 | |
| US60/686,215 | 2005-06-01 | ||
| US73807805P | 2005-11-19 | 2005-11-19 | |
| US60/738,078 | 2005-11-19 | ||
| PCT/US2006/021558 WO2006130855A2 (en) | 2005-06-01 | 2006-06-01 | Method of targeted gene delivery using viral vectors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008541768A JP2008541768A (ja) | 2008-11-27 |
| JP2008541768A5 true JP2008541768A5 (https=) | 2013-05-23 |
| JP5553989B2 JP5553989B2 (ja) | 2014-07-23 |
Family
ID=37482360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008514924A Expired - Fee Related JP5553989B2 (ja) | 2005-06-01 | 2006-06-01 | ウィルスベクターを使用した標的化遺伝子送達方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20070020238A1 (https=) |
| EP (2) | EP1885186B1 (https=) |
| JP (1) | JP5553989B2 (https=) |
| AU (1) | AU2006252406B2 (https=) |
| CA (1) | CA2611056C (https=) |
| WO (1) | WO2006130855A2 (https=) |
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| US8329162B2 (en) | 2006-07-21 | 2012-12-11 | California Institute Of Technology | Targeted gene delivery for dendritic cell vaccination |
| US8119772B2 (en) | 2006-09-29 | 2012-02-21 | California Institute Of Technology | MART-1 T cell receptors |
| DK2185192T3 (en) * | 2007-08-03 | 2019-02-18 | Pasteur Institut | LENTIVIRAL TRANSFER VECTORS AND THEIR MEDICAL USES |
| WO2010117786A1 (en) | 2009-03-30 | 2010-10-14 | Mount Sinai School Of Medicine Of New York University | Influenza virus vaccines and uses thereof |
| US8673314B2 (en) | 2009-05-26 | 2014-03-18 | Mount Sinai School Of Medicine | Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof |
| US20110015256A1 (en) * | 2009-07-16 | 2011-01-20 | Ihab Mamdouh Ishak Sadek | Delivery of restriction endonucleases to treat hiv, cancer, and other medical conditions |
| RS53257B2 (sr) | 2009-07-24 | 2018-06-29 | Immune Design Corp | Lentiviralni vektori pseudotipizirani sa omotačem od glikobelančevine iz sindbis-virusa |
| EP2536425B1 (en) | 2010-02-18 | 2019-06-19 | Icahn School of Medicine at Mount Sinai | Vaccines for use in the prophylaxis and treatment of influenza virus disease |
| CN102939103A (zh) | 2010-03-30 | 2013-02-20 | 西奈山医学院 | 流感病毒疫苗及其应用 |
| EA027236B1 (ru) | 2011-04-08 | 2017-07-31 | Иммьюн Дизайн Корп. | Иммуногенные композиции и способы применения таких композиций для индукции гуморального и клеточного иммунного ответа |
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2006
- 2006-06-01 EP EP06772026.8A patent/EP1885186B1/en active Active
- 2006-06-01 US US11/446,353 patent/US20070020238A1/en not_active Abandoned
- 2006-06-01 JP JP2008514924A patent/JP5553989B2/ja not_active Expired - Fee Related
- 2006-06-01 EP EP15177471.8A patent/EP2963118B1/en active Active
- 2006-06-01 AU AU2006252406A patent/AU2006252406B2/en not_active Ceased
- 2006-06-01 WO PCT/US2006/021558 patent/WO2006130855A2/en not_active Ceased
- 2006-06-01 CA CA2611056A patent/CA2611056C/en active Active
-
2011
- 2011-03-04 US US13/041,115 patent/US8821856B2/en active Active
-
2014
- 2014-07-23 US US14/338,947 patent/US9994867B2/en active Active
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