JP2008541768A5 - - Google Patents
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- JP2008541768A5 JP2008541768A5 JP2008514924A JP2008514924A JP2008541768A5 JP 2008541768 A5 JP2008541768 A5 JP 2008541768A5 JP 2008514924 A JP2008514924 A JP 2008514924A JP 2008514924 A JP2008514924 A JP 2008514924A JP 2008541768 A5 JP2008541768 A5 JP 2008541768A5
- Authority
- JP
- Japan
- Prior art keywords
- recombinant retrovirus
- antibody
- cell
- fusion molecule
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 230000004927 fusion Effects 0.000 claims description 16
- 108090000623 proteins and genes Proteins 0.000 claims description 10
- 241000700605 Viruses Species 0.000 claims description 6
- 206010028980 Neoplasm Diseases 0.000 claims description 4
- 102000004169 proteins and genes Human genes 0.000 claims description 4
- 239000013598 vector Substances 0.000 claims description 4
- 238000001727 in vivo Methods 0.000 claims description 3
- 201000011510 cancer Diseases 0.000 claims description 2
- 239000012528 membrane Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 25
- 241001430294 unidentified retrovirus Species 0.000 claims 17
- 230000009870 specific binding Effects 0.000 claims 8
- 108060003951 Immunoglobulin Proteins 0.000 claims 4
- 102000018358 immunoglobulin Human genes 0.000 claims 4
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 230000003612 virological effect Effects 0.000 claims 4
- 102000003886 Glycoproteins Human genes 0.000 claims 3
- 108090000288 Glycoproteins Proteins 0.000 claims 3
- 238000004806 packaging method and process Methods 0.000 claims 3
- 241000713666 Lentivirus Species 0.000 claims 2
- 230000027455 binding Effects 0.000 claims 2
- 241000178568 Aura virus Species 0.000 claims 1
- 241000724653 Borna disease virus Species 0.000 claims 1
- 241000725619 Dengue virus Species 0.000 claims 1
- 206010066919 Epidemic polyarthritis Diseases 0.000 claims 1
- 108700028146 Genetic Enhancer Elements Proteins 0.000 claims 1
- 101710154606 Hemagglutinin Proteins 0.000 claims 1
- 241000700721 Hepatitis B virus Species 0.000 claims 1
- 206010023927 Lassa fever Diseases 0.000 claims 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 1
- 101710176177 Protein A56 Proteins 0.000 claims 1
- 241000711798 Rabies lyssavirus Species 0.000 claims 1
- 108700008625 Reporter Genes Proteins 0.000 claims 1
- 241000710942 Ross River virus Species 0.000 claims 1
- 241000315672 SARS coronavirus Species 0.000 claims 1
- 241000710961 Semliki Forest virus Species 0.000 claims 1
- 108020004459 Small interfering RNA Proteins 0.000 claims 1
- 241000710771 Tick-borne encephalitis virus Species 0.000 claims 1
- 239000000185 hemagglutinin Substances 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 description 6
- 108091007433 antigens Proteins 0.000 description 3
- 230000035800 maturation Effects 0.000 description 3
- 230000008685 targeting Effects 0.000 description 3
- 102100033486 Lymphocyte antigen 75 Human genes 0.000 description 2
- 101710157884 Lymphocyte antigen 75 Proteins 0.000 description 2
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108010029697 CD40 Ligand Proteins 0.000 description 1
- 230000005867 T cell response Effects 0.000 description 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 description 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 description 1
- 230000030741 antigen processing and presentation Effects 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 230000012202 endocytosis Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 210000003563 lymphoid tissue Anatomy 0.000 description 1
- 201000001441 melanoma Diseases 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68621505P | 2005-06-01 | 2005-06-01 | |
| US60/686,215 | 2005-06-01 | ||
| US73807805P | 2005-11-19 | 2005-11-19 | |
| US60/738,078 | 2005-11-19 | ||
| PCT/US2006/021558 WO2006130855A2 (en) | 2005-06-01 | 2006-06-01 | Method of targeted gene delivery using viral vectors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008541768A JP2008541768A (ja) | 2008-11-27 |
| JP2008541768A5 true JP2008541768A5 (enExample) | 2013-05-23 |
| JP5553989B2 JP5553989B2 (ja) | 2014-07-23 |
Family
ID=37482360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008514924A Expired - Fee Related JP5553989B2 (ja) | 2005-06-01 | 2006-06-01 | ウィルスベクターを使用した標的化遺伝子送達方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20070020238A1 (enExample) |
| EP (2) | EP1885186B1 (enExample) |
| JP (1) | JP5553989B2 (enExample) |
| AU (1) | AU2006252406B2 (enExample) |
| CA (1) | CA2611056C (enExample) |
| WO (1) | WO2006130855A2 (enExample) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2006252406B2 (en) | 2005-06-01 | 2012-05-17 | California Institute Of Technology | Method of targeted gene delivery using viral vectors |
| SG173337A1 (en) | 2006-07-21 | 2011-08-29 | California Inst Of Techn | Targeted gene delivery for dendritic cell vaccination |
| US8119772B2 (en) | 2006-09-29 | 2012-02-21 | California Institute Of Technology | MART-1 T cell receptors |
| WO2009019612A2 (en) * | 2007-08-03 | 2009-02-12 | Institut Pasteur | Lentiviral gene transfer vectors and their medicinal applications |
| EP2413962A1 (en) | 2009-03-30 | 2012-02-08 | Mount Sinai School of Medicine | Influenza virus vaccines and uses thereof |
| AU2010254136B2 (en) | 2009-05-26 | 2016-09-29 | Mount Sinai School Of Medicine | Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof |
| US20110015256A1 (en) * | 2009-07-16 | 2011-01-20 | Ihab Mamdouh Ishak Sadek | Delivery of restriction endonucleases to treat hiv, cancer, and other medical conditions |
| WO2011011584A1 (en) | 2009-07-24 | 2011-01-27 | Immune Design Corp | Lentiviral vectors pseudotyped with a sindbis virus envelope glycoprotein |
| AU2011217903B2 (en) | 2010-02-18 | 2017-03-02 | Mount Sinai School Of Medicine | Vaccines for use in the prophylaxis and treatment of influenza virus disease |
| MX2012011300A (es) | 2010-03-30 | 2012-11-29 | Sinai School Medicine | Vacunas del virus de influenza y usos de las mismas. |
| WO2012141984A1 (en) | 2011-04-08 | 2012-10-18 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
| IN2014CN02114A (enExample) | 2011-09-20 | 2015-05-29 | Sinai School Medicine | |
| WO2013052915A2 (en) | 2011-10-05 | 2013-04-11 | Genelux Corporation | Method for detecting replication or colonization of a biological therapeutic |
| US20140087362A1 (en) | 2012-03-16 | 2014-03-27 | Aladar A. Szalay | Methods for assessing effectiveness and monitoring oncolytic virus treatment |
| EP2831095B1 (en) | 2012-03-30 | 2018-11-28 | Immune Design Corp. | Lentiviral vector particles having improved transduction efficiency for cells expressing dc-sign |
| US8323662B1 (en) | 2012-03-30 | 2012-12-04 | Immune Design Corp. | Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein |
| US9713635B2 (en) | 2012-03-30 | 2017-07-25 | Immune Design Corp. | Materials and methods for producing improved lentiviral vector particles |
| US20130280170A1 (en) | 2012-04-20 | 2013-10-24 | Aladar A. Szalay | Imaging methods for oncolytic virus therapy |
| WO2014039044A1 (en) | 2012-09-06 | 2014-03-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of producing t memory stem cell populations |
| WO2014055960A1 (en) | 2012-10-05 | 2014-04-10 | Genelux Corporation | Energy absorbing-based diagnostic and therapeutic methods employing nucleic acid molecules encoding chromophore-producing enzymes |
| EP4154907A1 (en) | 2012-12-18 | 2023-03-29 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
| WO2014159960A1 (en) | 2013-03-14 | 2014-10-02 | Icahn School Of Medicine At Mount Sinai | Antibodies against influenza virus hemagglutinin and uses thereof |
| GB201308772D0 (en) * | 2013-05-15 | 2013-06-26 | Imp Innovations Ltd | Vectors |
| US10238700B2 (en) | 2014-01-02 | 2019-03-26 | Genelux Corporation | Oncolytic virus adjunct therapy with agents that increase virus infectivity |
| EP3095864B1 (en) * | 2014-01-14 | 2020-04-15 | Kagoshima University | Method for labelling cancerization-causing cell in stem cells |
| MX384640B (es) * | 2014-08-06 | 2025-03-14 | Astellas Pharma Inc | ANTICUERPO IGß ANTIHUMANO NOVEDOSO. |
| JP7080055B2 (ja) * | 2014-09-08 | 2022-06-03 | ルタナ ゲーエムベーハー | 細胞の細胞質への分子の送達のための構築物 |
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| JP2018504412A (ja) | 2015-01-23 | 2018-02-15 | アイカーン スクール オブ メディシン アット マウント サイナイ | インフルエンザウイルスワクチン接種レジメン |
| WO2017004130A1 (en) * | 2015-06-29 | 2017-01-05 | Regents Of The University Of Minnesota | Degradation or neutralization of apobec3b by simian immunodeficiency virus vif |
| CA3004132A1 (en) | 2015-11-09 | 2017-05-18 | Immune Design Corp. | A retroviral vector for the administration and expression of replicon rna expressing heterologous nucleic acids |
| MX2018010061A (es) | 2016-02-23 | 2019-07-04 | Immune Design Corp | Preparaciones de vectores retrovirales de genomas multiples, y metodos y sistemas para producir y usar las mismas. |
| EP3377637B1 (en) * | 2016-04-08 | 2020-03-18 | Krystal Biotech, LLC | Compositions for use in methods for the treatment of wounds, disorders, and diseases of the skin |
| US11185555B2 (en) | 2016-04-11 | 2021-11-30 | Noah James Harrison | Method to kill pathogenic microbes in a patient |
| EP3443000B1 (en) | 2016-04-15 | 2025-11-12 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| KR102824067B1 (ko) | 2016-04-15 | 2025-06-23 | 알파인 이뮨 사이언시즈, 인코포레이티드 | Icos 리간드 변이체 면역조절 단백질 및 그의 용도 |
| WO2017218624A1 (en) | 2016-06-15 | 2017-12-21 | Icahn School Of Medicine At Mount Sinai | Influenza virus hemagglutinin proteins and uses thereof |
| US11834490B2 (en) | 2016-07-28 | 2023-12-05 | Alpine Immune Sciences, Inc. | CD112 variant immunomodulatory proteins and uses thereof |
| US11471488B2 (en) | 2016-07-28 | 2022-10-18 | Alpine Immune Sciences, Inc. | CD155 variant immunomodulatory proteins and uses thereof |
| CN110088127A (zh) | 2016-07-28 | 2019-08-02 | 高山免疫科学股份有限公司 | Cd155变体免疫调节蛋白及其用途 |
| AU2017345764A1 (en) | 2016-10-20 | 2019-05-02 | Alpine Immune Sciences, Inc. | Secretable variant immunomodulatory proteins and engineered cell therapy |
| AU2018219895C1 (en) | 2017-02-09 | 2024-10-03 | Indapta Therapeutics, Inc. | Engineered Natural Killer (NK) cells and compositions and methods thereof |
| LT3596116T (lt) | 2017-03-16 | 2023-11-10 | Alpine Immune Sciences, Inc. | Imunomoduliacinių baltymų pd-l1 variantai ir jų naudojimo būdai |
| CN110809581A (zh) | 2017-03-16 | 2020-02-18 | 高山免疫科学股份有限公司 | Pd-l2变体免疫调节蛋白及其用途 |
| CA3054068A1 (en) | 2017-03-16 | 2018-09-20 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| US11254733B2 (en) | 2017-04-07 | 2022-02-22 | Icahn School Of Medicine At Mount Sinai | Anti-influenza B virus neuraminidase antibodies and uses thereof |
| MX2020004540A (es) | 2017-10-18 | 2020-08-03 | Alpine Immune Sciences Inc | Proteinas inmunomoduladoras de ligando icos variante y composiciones y metodos relacionados. |
| EP3735417A1 (en) | 2018-01-03 | 2020-11-11 | Alpine Immune Sciences, Inc. | Multi-domain immunomodulatory proteins and methods of use thereof |
| CA3094345A1 (en) | 2018-04-12 | 2019-10-17 | Krystal Biotech, Inc. | Compositions and methods for the treatment of autosomal recessive congenital ichthyosis |
| CN112041434A (zh) | 2018-04-27 | 2020-12-04 | 克里斯托生物技术股份有限公司 | 用于美容性应用的编码一种或多种美容蛋白的重组核酸 |
| US11505782B2 (en) | 2018-06-04 | 2022-11-22 | Calidi Biotherapeutics, Inc. | Cell-based vehicles for potentiation of viral therapy |
| ES2966045T3 (es) | 2018-06-04 | 2024-04-18 | Calidi Biotherapeutics Inc | Vehículos basados en células para la potenciación de la terapia viral |
| WO2019241758A1 (en) | 2018-06-15 | 2019-12-19 | Alpine Immune Sciences, Inc. | Pd-1 variant immunomodulatory proteins and uses thereof |
| EP3810634A4 (en) | 2018-06-21 | 2022-07-27 | Icahn School of Medicine at Mount Sinai | Mosaic influenza virus hemagglutinin polypeptides and uses thereof |
| WO2020047161A2 (en) | 2018-08-28 | 2020-03-05 | Actym Therapeutics, Inc. | Engineered immunostimulatory bacterial strains and uses thereof |
| JP7562515B2 (ja) | 2018-09-24 | 2024-10-07 | クリスタル バイオテック インコーポレイテッド | ネザートン症候群の治療のための組成物及び方法 |
| AU2019377141B2 (en) | 2018-11-06 | 2024-06-06 | Calidi Biotherapeutics (Nevada), Inc. | Enhanced systems for cell-mediated oncolytic viral therapy |
| CN113891934A (zh) | 2018-11-21 | 2022-01-04 | 因达普塔治疗公司 | 扩增天然杀伤（nk）细胞子集的方法以及相关组合物和方法 |
| CN113727998A (zh) | 2018-11-30 | 2021-11-30 | 高山免疫科学股份有限公司 | Cd86变体免疫调节蛋白及其用途 |
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| CN114127305A (zh) | 2019-05-23 | 2022-03-01 | 麻省理工学院 | 经由逆转录病毒表面展示的配体发现和基因递送 |
| CN114258398A (zh) | 2019-06-13 | 2022-03-29 | 总医院公司 | 工程化的人内源性病毒样颗粒及使用其递送至细胞的方法 |
| CN116368221A (zh) | 2020-04-22 | 2023-06-30 | 因达普塔治疗公司 | 自然杀伤(nk)细胞组合物及其生成方法 |
| BR112023001272A2 (pt) | 2020-07-24 | 2023-04-04 | Massachusetts Gen Hospital | Partículas semelhantes a vírus aprimoradas e métodos de uso das mesmas para entrega às células |
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| AU2022227021A1 (en) | 2021-02-26 | 2023-09-21 | Kelonia Therapeutics, Inc. | Lymphocyte targeted lentiviral vectors |
| JP2024513826A (ja) | 2021-04-02 | 2024-03-27 | クリスタル バイオテック インコーポレイテッド | がん治療のためのウイルスベクター |
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| WO2023240124A1 (en) | 2022-06-07 | 2023-12-14 | Regeneron Pharmaceuticals, Inc. | Pseudotyped viral particles for targeting tcr-expressing cells |
| US12440564B2 (en) | 2023-09-25 | 2025-10-14 | Kelonia Therapeutics, Inc. | Compositions for treating cancer |
| US12269882B1 (en) | 2023-09-25 | 2025-04-08 | Kelonia Therapeutics, Inc. | Antigen binding polypeptides |
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| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US4937190A (en) | 1987-10-15 | 1990-06-26 | Wisconsin Alumni Research Foundation | Translation enhancer |
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| US6534051B1 (en) * | 1992-11-20 | 2003-03-18 | University Of Medicine And Dentistry Of New Jersey | Cell type specific gene transfer using retroviral vectors containing antibody-envelope fusion proteins and wild-type envelope fusion proteins |
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| GB0417494D0 (en) | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
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| AU2006252406B2 (en) * | 2005-06-01 | 2012-05-17 | California Institute Of Technology | Method of targeted gene delivery using viral vectors |
| SG173337A1 (en) | 2006-07-21 | 2011-08-29 | California Inst Of Techn | Targeted gene delivery for dendritic cell vaccination |
| RS56844B1 (sr) | 2007-12-11 | 2018-04-30 | Univ North Carolina Chapel Hill | Retrovirusni vektori sa modifikovanim polipurinskim nizom |
-
2006
- 2006-06-01 AU AU2006252406A patent/AU2006252406B2/en not_active Ceased
- 2006-06-01 CA CA2611056A patent/CA2611056C/en active Active
- 2006-06-01 US US11/446,353 patent/US20070020238A1/en not_active Abandoned
- 2006-06-01 WO PCT/US2006/021558 patent/WO2006130855A2/en not_active Ceased
- 2006-06-01 EP EP06772026.8A patent/EP1885186B1/en active Active
- 2006-06-01 EP EP15177471.8A patent/EP2963118B1/en active Active
- 2006-06-01 JP JP2008514924A patent/JP5553989B2/ja not_active Expired - Fee Related
-
2011
- 2011-03-04 US US13/041,115 patent/US8821856B2/en active Active
-
2014
- 2014-07-23 US US14/338,947 patent/US9994867B2/en active Active
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