JP2008540362A - 抗腫瘍性テトラヒドロピリミジン - Google Patents

抗腫瘍性テトラヒドロピリミジン Download PDF

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Publication number
JP2008540362A
JP2008540362A JP2008509372A JP2008509372A JP2008540362A JP 2008540362 A JP2008540362 A JP 2008540362A JP 2008509372 A JP2008509372 A JP 2008509372A JP 2008509372 A JP2008509372 A JP 2008509372A JP 2008540362 A JP2008540362 A JP 2008540362A
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JP
Japan
Prior art keywords
substituted
unsubstituted
alkyl
compound
group
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2008509372A
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English (en)
Japanese (ja)
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JP2008540362A5 (https=
Inventor
ホセ、フェルナンド、レジェス、ベニテス
マリア、デル、カルメン、クエバス、マルチャンテ
ダビ、モンタルボ、ロボ
マリア、ヘスス、マルティン、ロペス
マリア、クリスティーナ、マテオ、ウルバノ
アンドレス、フランセスク、ソリョーソ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharma Mrs sA
Original Assignee
Pharma Mrs sA
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Application filed by Pharma Mrs sA filed Critical Pharma Mrs sA
Publication of JP2008540362A publication Critical patent/JP2008540362A/ja
Publication of JP2008540362A5 publication Critical patent/JP2008540362A5/ja
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2008509372A 2005-05-03 2006-05-03 抗腫瘍性テトラヒドロピリミジン Withdrawn JP2008540362A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05076037 2005-05-03
PCT/EP2006/004117 WO2006117197A1 (en) 2005-05-03 2006-05-03 Antitumoral tetrahydro-pyrimidines

Publications (2)

Publication Number Publication Date
JP2008540362A true JP2008540362A (ja) 2008-11-20
JP2008540362A5 JP2008540362A5 (https=) 2009-06-18

Family

ID=36649783

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008509372A Withdrawn JP2008540362A (ja) 2005-05-03 2006-05-03 抗腫瘍性テトラヒドロピリミジン

Country Status (13)

Country Link
US (1) US20100216817A1 (https=)
EP (1) EP1879870A1 (https=)
JP (1) JP2008540362A (https=)
KR (1) KR20080007640A (https=)
CN (1) CN101171236A (https=)
AU (1) AU2006243407A1 (https=)
CA (1) CA2605784A1 (https=)
EA (1) EA013160B1 (https=)
IL (1) IL186781A0 (https=)
MX (1) MX2007013683A (https=)
NO (1) NO20076162L (https=)
NZ (1) NZ563054A (https=)
WO (1) WO2006117197A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102210868A (zh) * 2011-04-29 2011-10-12 济南环肽医药科技有限公司 四氢嘧啶及其衍生物在制备口服吸收促进剂中的应用
HRP20231233T1 (hr) 2017-04-27 2024-01-19 Pharma Mar, S.A. Antitumorski spojevi
CN108120792B (zh) * 2017-12-14 2020-03-24 青海出入境检验检疫局检验检疫综合技术中心 一种四氢嘧啶的高效液相检测及含量测定方法
CN110156697B (zh) * 2019-05-30 2022-05-06 常州沃腾化工科技有限公司 一种1,2-二甲基-1,4,5,6-四氢嘧啶的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2743255A (en) * 1952-12-19 1956-04-24 Petrolite Corp Amine-modified thermoplastic phenolaldehyde resins and method of making same
US4292429A (en) * 1978-03-08 1981-09-29 Ciba-Geigy Corporation Imidazole urea and amido compounds

Also Published As

Publication number Publication date
NZ563054A (en) 2010-09-30
MX2007013683A (es) 2007-12-03
EA013160B1 (ru) 2010-02-26
CA2605784A1 (en) 2006-11-09
EP1879870A1 (en) 2008-01-23
US20100216817A1 (en) 2010-08-26
IL186781A0 (en) 2008-02-09
NO20076162L (no) 2007-11-29
WO2006117197A1 (en) 2006-11-09
CN101171236A (zh) 2008-04-30
AU2006243407A1 (en) 2006-11-09
EA200702397A1 (ru) 2008-02-28
KR20080007640A (ko) 2008-01-22

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