JP2008539273A - １７−ａａｇ又は１７−ａｇ又はどちらかのプロドラッグをプロテアソーム阻害剤と組み合わせて使用する多発性骨髄腫の治療方法 - Google Patents
１７−ａａｇ又は１７−ａｇ又はどちらかのプロドラッグをプロテアソーム阻害剤と組み合わせて使用する多発性骨髄腫の治療方法 Download PDFInfo
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
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| US67655605P | 2005-04-29 | 2005-04-29 | |
| US68623205P | 2005-05-31 | 2005-05-31 | |
| US74919005P | 2005-12-09 | 2005-12-09 | |
| PCT/US2006/016283 WO2006119032A1 (en) | 2005-04-29 | 2006-04-26 | Method of treating multiple myeloma using 17-aag or 17-ag or a prodrug of either in combination with a proteasome inhibitor |
Publications (2)
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| JP2008539273A true JP2008539273A (ja) | 2008-11-13 |
| JP2008539273A5 JP2008539273A5 (enExample) | 2009-06-18 |
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| JP2008509175A Abandoned JP2008539273A (ja) | 2005-04-29 | 2006-04-26 | １７−ａａｇ又は１７−ａｇ又はどちらかのプロドラッグをプロテアソーム阻害剤と組み合わせて使用する多発性骨髄腫の治療方法 |
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| US (1) | US20060252740A1 (enExample) |
| EP (1) | EP1874297A4 (enExample) |
| JP (1) | JP2008539273A (enExample) |
| KR (1) | KR20080007642A (enExample) |
| AU (1) | AU2006242446A1 (enExample) |
| BR (1) | BRPI0609861A2 (enExample) |
| CA (1) | CA2604424A1 (enExample) |
| IL (1) | IL186293A0 (enExample) |
| MX (1) | MX2007013499A (enExample) |
| WO (1) | WO2006119032A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009538881A (ja) * | 2006-06-01 | 2009-11-12 | ヴィロローギク ゲゼルシャフト ミット ベシュレンクテル ハフツング | タンパク質フォールディング及びタンパク質分解の阻害による、ウィルス感染及び／又は腫瘍疾患の治療のための医薬組成物 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6872715B2 (en) * | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
| US20090197852A9 (en) * | 2001-08-06 | 2009-08-06 | Johnson Robert G Jr | Method of treating breast cancer using 17-AAG or 17-AG or a prodrug of either in combination with a HER2 inhibitor |
| US20050026893A1 (en) * | 2003-05-30 | 2005-02-03 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with immunosuppressants |
| US20050020534A1 (en) * | 2003-05-30 | 2005-01-27 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with antimetabolites |
| US20050020556A1 (en) * | 2003-05-30 | 2005-01-27 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with platinum coordination complexes |
| WO2006118953A2 (en) * | 2005-04-29 | 2006-11-09 | Kosan Biosciences Incorporated | Method of treating multiple myeloma using 17-aag of 17-ag of a prodrug of either |
| PE20081506A1 (es) * | 2006-12-12 | 2008-12-09 | Infinity Discovery Inc | Formulaciones de ansamicina |
| CA2680161A1 (en) * | 2007-03-05 | 2008-09-12 | Kyowa Hakko Kirin Co., Ltd. | Pharmaceutical composition |
| US7442830B1 (en) | 2007-08-06 | 2008-10-28 | Millenium Pharmaceuticals, Inc. | Proteasome inhibitors |
| US8754094B2 (en) * | 2007-08-15 | 2014-06-17 | The Research Foundation Of State University Of New York | Methods for heat shock protein dependent cancer treatment |
| US20110118274A1 (en) * | 2007-08-23 | 2011-05-19 | Cornell Research Foundation, Inc. | Proteasome inhibitors and their use in treating pathogen infection and cancer |
| US8672869B2 (en) * | 2007-10-30 | 2014-03-18 | Bellco S.R.L. | Kit, system and method of treating myeloma patients |
| WO2009143290A2 (en) * | 2008-05-20 | 2009-11-26 | Cleveland Biolabs, Inc | Inducing cell death by inhibiting adaptive heat shock response |
| ES2585114T3 (es) | 2008-06-17 | 2016-10-03 | Millennium Pharmaceuticals, Inc. | Compuestos de ésteres boronato y composiciones farmacéuticas de los mismos |
| WO2010054381A2 (en) * | 2008-11-10 | 2010-05-14 | Mount Sinai School Of Medicine Of New York University | Method of treating cancer with a combination of a proteasome inhibitor and salubrinal |
| AU2009347159B2 (en) * | 2009-05-27 | 2015-09-03 | Cephalon, Inc. | Combination therapy for the treatment of multiple myeloma |
| CA2949517A1 (en) | 2014-05-20 | 2015-11-26 | Millennium Pharmaceuticals, Inc. | Boron-containing proteasome inhibitors for use after primary cancer therapy |
| WO2016205538A1 (en) * | 2015-06-16 | 2016-12-22 | Mayo Foundation For Medical Education And Research | Methods and materials for assessing hydrogen peroxide accumulation in cells |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4261989A (en) * | 1979-02-19 | 1981-04-14 | Kaken Chemical Co. Ltd. | Geldanamycin derivatives and antitumor drug |
| CA2132711C (en) * | 1992-03-23 | 2005-02-08 | Aquilar Rahman | Liposome encapsulated paclitaxel and a method of using the same |
| US5387584A (en) * | 1993-04-07 | 1995-02-07 | Pfizer Inc. | Bicyclic ansamycins |
| WO1994026254A1 (en) * | 1993-05-17 | 1994-11-24 | The Liposome Company, Inc. | Incorporation of taxol into liposomes and gels |
| US5415869A (en) * | 1993-11-12 | 1995-05-16 | The Research Foundation Of State University Of New York | Taxol formulation |
| US5932566A (en) * | 1994-06-16 | 1999-08-03 | Pfizer Inc. | Ansamycin derivatives as antioncogene and anticancer agents |
| US6083903A (en) * | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
| US5662883A (en) * | 1995-01-10 | 1997-09-02 | Nanosystems L.L.C. | Microprecipitation of micro-nanoparticulate pharmaceutical agents |
| US5534270A (en) * | 1995-02-09 | 1996-07-09 | Nanosystems Llc | Method of preparing stable drug nanoparticles |
| US5510118A (en) * | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| US6682758B1 (en) * | 1998-12-22 | 2004-01-27 | The United States Of America As Represented By The Department Of Health And Human Services | Water-insoluble drug delivery system |
| AU2002243646B2 (en) * | 2001-01-25 | 2006-06-22 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Formulation of boronic acid compounds |
| US6890917B2 (en) * | 2001-03-30 | 2005-05-10 | The United States Of America As Represented By The Department Of Health And Human Services | Geldanamycin derivative and method of treating cancer using same |
| US20050043233A1 (en) * | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
| US6887993B1 (en) * | 2003-11-12 | 2005-05-03 | Kosan Biosciences, Inc. | 11-O-methylgeldanamycin compounds |
| US20050256097A1 (en) * | 2004-05-11 | 2005-11-17 | Kosan Biosciences, Inc. | Pharmaceutical solution formulations containing 17-AAG |
| US20060067953A1 (en) * | 2004-09-29 | 2006-03-30 | Conforma Therapeutics Corporation | Oral pharmaceutical formulations and methods for producing and using same |
| SG171690A1 (en) * | 2005-03-22 | 2011-06-29 | Harvard College | Treatment of protein degradation disorders |
-
2006
- 2006-04-26 AU AU2006242446A patent/AU2006242446A1/en not_active Abandoned
- 2006-04-26 EP EP06758739A patent/EP1874297A4/en not_active Withdrawn
- 2006-04-26 MX MX2007013499A patent/MX2007013499A/es not_active Application Discontinuation
- 2006-04-26 JP JP2008509175A patent/JP2008539273A/ja not_active Abandoned
- 2006-04-26 KR KR1020077027765A patent/KR20080007642A/ko not_active Withdrawn
- 2006-04-26 WO PCT/US2006/016283 patent/WO2006119032A1/en not_active Ceased
- 2006-04-26 US US11/412,299 patent/US20060252740A1/en not_active Abandoned
- 2006-04-26 CA CA002604424A patent/CA2604424A1/en not_active Abandoned
- 2006-04-26 BR BRPI0609861-4A patent/BRPI0609861A2/pt not_active IP Right Cessation
-
2007
- 2007-09-25 IL IL186293A patent/IL186293A0/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009538881A (ja) * | 2006-06-01 | 2009-11-12 | ヴィロローギク ゲゼルシャフト ミット ベシュレンクテル ハフツング | タンパク質フォールディング及びタンパク質分解の阻害による、ウィルス感染及び／又は腫瘍疾患の治療のための医薬組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| MX2007013499A (es) | 2008-01-24 |
| WO2006119032A1 (en) | 2006-11-09 |
| KR20080007642A (ko) | 2008-01-22 |
| US20060252740A1 (en) | 2006-11-09 |
| BRPI0609861A2 (pt) | 2010-05-11 |
| IL186293A0 (en) | 2008-01-20 |
| CA2604424A1 (en) | 2006-11-09 |
| EP1874297A1 (en) | 2008-01-09 |
| EP1874297A4 (en) | 2009-04-22 |
| AU2006242446A1 (en) | 2006-11-09 |
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