CA2604424A1 - Method of treating multiple myeloma using 17-aag or 17-ag or a prodrug of either in combination with a proteasome inhibitor - Google Patents
Method of treating multiple myeloma using 17-aag or 17-ag or a prodrug of either in combination with a proteasome inhibitor Download PDFInfo
- Publication number
- CA2604424A1 CA2604424A1 CA002604424A CA2604424A CA2604424A1 CA 2604424 A1 CA2604424 A1 CA 2604424A1 CA 002604424 A CA002604424 A CA 002604424A CA 2604424 A CA2604424 A CA 2604424A CA 2604424 A1 CA2604424 A1 CA 2604424A1
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- aag
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- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67655605P | 2005-04-29 | 2005-04-29 | |
| US60/676,556 | 2005-04-29 | ||
| US68623205P | 2005-05-31 | 2005-05-31 | |
| US60/686,232 | 2005-05-31 | ||
| US74919005P | 2005-12-09 | 2005-12-09 | |
| US60/749,190 | 2005-12-09 | ||
| PCT/US2006/016283 WO2006119032A1 (en) | 2005-04-29 | 2006-04-26 | Method of treating multiple myeloma using 17-aag or 17-ag or a prodrug of either in combination with a proteasome inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2604424A1 true CA2604424A1 (en) | 2006-11-09 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002604424A Abandoned CA2604424A1 (en) | 2005-04-29 | 2006-04-26 | Method of treating multiple myeloma using 17-aag or 17-ag or a prodrug of either in combination with a proteasome inhibitor |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20060252740A1 (enExample) |
| EP (1) | EP1874297A4 (enExample) |
| JP (1) | JP2008539273A (enExample) |
| KR (1) | KR20080007642A (enExample) |
| AU (1) | AU2006242446A1 (enExample) |
| BR (1) | BRPI0609861A2 (enExample) |
| CA (1) | CA2604424A1 (enExample) |
| IL (1) | IL186293A0 (enExample) |
| MX (1) | MX2007013499A (enExample) |
| WO (1) | WO2006119032A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090197852A9 (en) * | 2001-08-06 | 2009-08-06 | Johnson Robert G Jr | Method of treating breast cancer using 17-AAG or 17-AG or a prodrug of either in combination with a HER2 inhibitor |
| US6872715B2 (en) * | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
| US20050020534A1 (en) * | 2003-05-30 | 2005-01-27 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with antimetabolites |
| US20050026893A1 (en) * | 2003-05-30 | 2005-02-03 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with immunosuppressants |
| US20050020556A1 (en) * | 2003-05-30 | 2005-01-27 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with platinum coordination complexes |
| KR20080000682A (ko) * | 2005-04-29 | 2008-01-02 | 코산 바이오사이언시즈, 인코포레이티드 | 17-ａａｇ 또는 17-ａｇ, 또는 이들의 프로드럭을 사용한다발성 골수종의 치료 방법 |
| DE102006026464A1 (de) * | 2006-06-01 | 2007-12-06 | Virologik Gmbh Innovationszentrum Medizintechnik Und Pharma | Pharmazeutische Zusammensetzung zur Behandlung von Virusinfektionen und / oder Tumorerkrankungen durch Inhibition der Proteinfaltung und des Proteinabbaus |
| PE20081506A1 (es) * | 2006-12-12 | 2008-12-09 | Infinity Discovery Inc | Formulaciones de ansamicina |
| JPWO2008108386A1 (ja) * | 2007-03-05 | 2010-06-17 | 協和発酵キリン株式会社 | 医薬組成物 |
| US7442830B1 (en) | 2007-08-06 | 2008-10-28 | Millenium Pharmaceuticals, Inc. | Proteasome inhibitors |
| US8754094B2 (en) * | 2007-08-15 | 2014-06-17 | The Research Foundation Of State University Of New York | Methods for heat shock protein dependent cancer treatment |
| WO2009026579A1 (en) * | 2007-08-23 | 2009-02-26 | Cornell Research Foundation, Inc. | Proteasome inhibitors and their use in treating pathogen infection and cancer |
| US8672869B2 (en) * | 2007-10-30 | 2014-03-18 | Bellco S.R.L. | Kit, system and method of treating myeloma patients |
| US8486697B2 (en) * | 2008-05-20 | 2013-07-16 | Incuron, Llc | Inducing cell death by inhibiting adaptive heat shock response |
| GEP201706703B (en) | 2008-06-17 | 2017-07-25 | Millennium Pharmaceuticals Inc (A Delaware Corporation) | Boronate ester compounds and pharmaceutical compositions thereof |
| WO2010054381A2 (en) * | 2008-11-10 | 2010-05-14 | Mount Sinai School Of Medicine Of New York University | Method of treating cancer with a combination of a proteasome inhibitor and salubrinal |
| WO2010138141A1 (en) | 2009-05-27 | 2010-12-02 | Cephalon, Inc. | Combination therapy for the treatment of multiple myeloma |
| KR102509950B1 (ko) | 2014-05-20 | 2023-03-14 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | 일차 암 치료법 후 사용하기 위한 붕소-함유 프로테아좀 저해제 |
| WO2016205538A1 (en) * | 2015-06-16 | 2016-12-22 | Mayo Foundation For Medical Education And Research | Methods and materials for assessing hydrogen peroxide accumulation in cells |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4261989A (en) * | 1979-02-19 | 1981-04-14 | Kaken Chemical Co. Ltd. | Geldanamycin derivatives and antitumor drug |
| DK0706373T3 (da) * | 1992-03-23 | 2000-09-18 | Univ Georgetown | Liposomindkapslet taxol og en fremgangsmåde til anvendelse heraf |
| US5387584A (en) * | 1993-04-07 | 1995-02-07 | Pfizer Inc. | Bicyclic ansamycins |
| WO1994026254A1 (en) * | 1993-05-17 | 1994-11-24 | The Liposome Company, Inc. | Incorporation of taxol into liposomes and gels |
| US5415869A (en) * | 1993-11-12 | 1995-05-16 | The Research Foundation Of State University Of New York | Taxol formulation |
| US5932566A (en) * | 1994-06-16 | 1999-08-03 | Pfizer Inc. | Ansamycin derivatives as antioncogene and anticancer agents |
| US6083903A (en) * | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
| US5662883A (en) * | 1995-01-10 | 1997-09-02 | Nanosystems L.L.C. | Microprecipitation of micro-nanoparticulate pharmaceutical agents |
| US5534270A (en) * | 1995-02-09 | 1996-07-09 | Nanosystems Llc | Method of preparing stable drug nanoparticles |
| US5510118A (en) * | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| US6682758B1 (en) * | 1998-12-22 | 2004-01-27 | The United States Of America As Represented By The Department Of Health And Human Services | Water-insoluble drug delivery system |
| JP4162491B2 (ja) * | 2001-01-25 | 2008-10-08 | アメリカ合衆国 | ボロン酸化合物製剤 |
| WO2002079167A1 (en) * | 2001-03-30 | 2002-10-10 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Geldanamycin derivative and method of treating cancer using same |
| US20050043233A1 (en) * | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
| US6887993B1 (en) * | 2003-11-12 | 2005-05-03 | Kosan Biosciences, Inc. | 11-O-methylgeldanamycin compounds |
| US20050256097A1 (en) * | 2004-05-11 | 2005-11-17 | Kosan Biosciences, Inc. | Pharmaceutical solution formulations containing 17-AAG |
| US20060067953A1 (en) * | 2004-09-29 | 2006-03-30 | Conforma Therapeutics Corporation | Oral pharmaceutical formulations and methods for producing and using same |
| EP1861126A4 (en) * | 2005-03-22 | 2009-11-18 | Harvard College | TREATMENT OF PROTEIN REMOVAL TROUBLES |
-
2006
- 2006-04-26 EP EP06758739A patent/EP1874297A4/en not_active Withdrawn
- 2006-04-26 KR KR1020077027765A patent/KR20080007642A/ko not_active Withdrawn
- 2006-04-26 MX MX2007013499A patent/MX2007013499A/es not_active Application Discontinuation
- 2006-04-26 AU AU2006242446A patent/AU2006242446A1/en not_active Abandoned
- 2006-04-26 JP JP2008509175A patent/JP2008539273A/ja not_active Abandoned
- 2006-04-26 CA CA002604424A patent/CA2604424A1/en not_active Abandoned
- 2006-04-26 BR BRPI0609861-4A patent/BRPI0609861A2/pt not_active IP Right Cessation
- 2006-04-26 US US11/412,299 patent/US20060252740A1/en not_active Abandoned
- 2006-04-26 WO PCT/US2006/016283 patent/WO2006119032A1/en not_active Ceased
-
2007
- 2007-09-25 IL IL186293A patent/IL186293A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20060252740A1 (en) | 2006-11-09 |
| EP1874297A1 (en) | 2008-01-09 |
| BRPI0609861A2 (pt) | 2010-05-11 |
| IL186293A0 (en) | 2008-01-20 |
| WO2006119032A1 (en) | 2006-11-09 |
| JP2008539273A (ja) | 2008-11-13 |
| EP1874297A4 (en) | 2009-04-22 |
| AU2006242446A1 (en) | 2006-11-09 |
| KR20080007642A (ko) | 2008-01-22 |
| MX2007013499A (es) | 2008-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |