JP2008537673A5 - - Google Patents
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- Publication number
- JP2008537673A5 JP2008537673A5 JP2007553371A JP2007553371A JP2008537673A5 JP 2008537673 A5 JP2008537673 A5 JP 2008537673A5 JP 2007553371 A JP2007553371 A JP 2007553371A JP 2007553371 A JP2007553371 A JP 2007553371A JP 2008537673 A5 JP2008537673 A5 JP 2008537673A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- ephb2
- seq
- hvr
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64854105P | 2005-01-31 | 2005-01-31 | |
| US75684406P | 2006-01-05 | 2006-01-05 | |
| PCT/US2006/003502 WO2006083936A2 (en) | 2005-01-31 | 2006-01-31 | Anti-ephb2 antibodies and methods using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008537673A JP2008537673A (ja) | 2008-09-25 |
| JP2008537673A5 true JP2008537673A5 (enExample) | 2009-02-26 |
Family
ID=36341431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007553371A Pending JP2008537673A (ja) | 2005-01-31 | 2006-01-31 | 抗ｅｐｈｂ２抗体とその使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7767205B2 (enExample) |
| EP (1) | EP1844076A2 (enExample) |
| JP (1) | JP2008537673A (enExample) |
| AU (1) | AU2006210837B2 (enExample) |
| CA (1) | CA2594636A1 (enExample) |
| NZ (1) | NZ556317A (enExample) |
| WO (1) | WO2006083936A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2369542T3 (es) | 2002-07-31 | 2011-12-01 | Seattle Genetics, Inc. | Conjugados de auristatina y su uso para tratar cáncer, una enfermedad autoinmune o una enfermedad infecciosa. |
| ES2605443T3 (es) | 2003-11-06 | 2017-03-14 | Seattle Genetics, Inc. | Conjugados de auristatina con anticuerpos anti-HER2 o anti-CD22 y su uso en terapia |
| JP2008519863A (ja) | 2004-11-12 | 2008-06-12 | シアトル ジェネティクス インコーポレイティッド | Ｎ末端にアミノ安息香酸単位を有するオーリスタチン |
| WO2006074392A2 (en) * | 2005-01-06 | 2006-07-13 | Genentech, Inc. | Cancer prognostic, diagnostic and treatment methods |
| WO2007008848A2 (en) | 2005-07-07 | 2007-01-18 | Seattle Genetics, Inc. | Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus |
| ES2708763T3 (es) | 2005-07-07 | 2019-04-11 | Seattle Genetics Inc | Compuestos de monometilvalina que tienen modificaciones de la cadena lateral de fenilalanina en el extremo C |
| US7750116B1 (en) | 2006-02-18 | 2010-07-06 | Seattle Genetics, Inc. | Antibody drug conjugate metabolites |
| JP2010501596A (ja) | 2006-08-31 | 2010-01-21 | エー・シー・エヌ・１３５ ４９３ ３９１・プロプライエタリー・リミテッド・アズ・トラスティー・フォー・コンカ・ユニット・トラスト | 抗体含有組成物を用いた非感染性の病状の処置および／または予防 |
| PE20140625A1 (es) | 2007-07-16 | 2014-05-29 | Genentech Inc | ANTICUERPOS ANTI-CD79b E INMUNOCONJUGADOS HUMANIZADOS |
| PT2474557E (pt) | 2007-07-16 | 2014-12-03 | Genentech Inc | Anticorpos e imunoconjugados anti-cd79b e métodos de utilização |
| US20090309617A1 (en) * | 2007-08-24 | 2009-12-17 | Ye Fang | Biosensor antibody functional mapping |
| DK2657253T3 (en) | 2008-01-31 | 2017-10-09 | Genentech Inc | Anti-CD79b antibodies and immune conjugates and methods of use |
| MX340078B (es) | 2009-11-07 | 2016-06-24 | Astute Medical Inc | Metodos y composiciones para el diagnostico y pronostico de daño renal y falla renal. |
| CN104640572B (zh) | 2012-05-15 | 2018-04-27 | 索伦托医疗有限公司 | 药物偶联物，偶联方法，及其用途 |
| PT3057585T (pt) | 2013-10-15 | 2020-10-21 | Seagen Inc | Fármaco-ligadores peguilados para farmacocinética melhorada de conjugados de fármaco-ligando |
| AU2014337317A1 (en) | 2013-10-15 | 2016-09-15 | Sorrento Therapeutics Inc. | Drug-conjugates with a targeting molecule and two different drugs |
| KR102301188B1 (ko) * | 2014-02-06 | 2021-09-13 | 엑스4 파마슈티컬스 (오스트리아) 게엠베하 | 이. 콜라이 특이성 항체 서열 |
| CA2979671C (en) | 2014-09-23 | 2020-03-10 | Genentech, Inc. | Methods of using anti-cd79b immunoconjugates |
| JP6871858B2 (ja) | 2015-01-28 | 2021-05-19 | ソレント・セラピューティクス・インコーポレイテッドＳｏｒｒｅｎｔｏ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | 抗体薬物コンジュゲート |
| WO2017089606A1 (en) * | 2015-11-26 | 2017-06-01 | Kotter Mark Reinhard | Therapy to increase remyelination |
| US11229708B2 (en) | 2015-12-04 | 2022-01-25 | Seagen Inc. | Conjugates of quaternized tubulysin compounds |
| US11793880B2 (en) | 2015-12-04 | 2023-10-24 | Seagen Inc. | Conjugates of quaternized tubulysin compounds |
| EP3433278A4 (en) | 2016-03-25 | 2019-11-06 | Seattle Genetics, Inc. | METHOD FOR THE PRODUCTION OF PEGYLATED ACTIVE LINKERS AND INTERMEDIATE PRODUCTS THEREOF |
| WO2017173091A1 (en) * | 2016-03-30 | 2017-10-05 | Musc Foundation For Research Development | Methods for treatment and diagnosis of cancer by targeting glycoprotein a repetitions predominant (garp) and for providing effective immunotherapy alone or in combination |
| JP7527787B2 (ja) | 2017-03-24 | 2024-08-05 | シージェン インコーポレイテッド | グルクロニド薬物－リンカーの調製のためのプロセスおよびその中間体 |
| EP4168019A4 (en) * | 2020-06-17 | 2024-07-31 | 4C Biomed Services Ltd. | ANTIBODIES AGAINST EPHB2 AND ITS USE IN COMBINATION THERAPY |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5622701A (en) * | 1994-06-14 | 1997-04-22 | Protein Design Labs, Inc. | Cross-reacting monoclonal antibodies specific for E- and P-selectin |
| DE60127291T2 (de) * | 2000-11-20 | 2007-12-20 | California Institute Of Technology, Pasadena | Für den glatten muskel von arterien und den glatten muskel von venen spezifische proteine und deren verwendung |
| EP1409549A4 (en) * | 2001-06-20 | 2007-10-24 | Genentech Inc | COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMORS |
| CN1678634A (zh) * | 2002-06-28 | 2005-10-05 | 多曼蒂斯有限公司 | 免疫球蛋白单个变体抗原结合区及其特异性构建体 |
| AU2003291736A1 (en) * | 2002-11-05 | 2004-06-03 | Cell Signaling Technology, Inc. | Methods and materials for examining pathways associated with glioblastoma progression |
| ES2605443T3 (es) * | 2003-11-06 | 2017-03-14 | Seattle Genetics, Inc. | Conjugados de auristatina con anticuerpos anti-HER2 o anti-CD22 y su uso en terapia |
| CA2559870A1 (en) * | 2004-04-07 | 2005-10-27 | Genetech,Inc. | Mass spectrometry of antibody conjugates |
| WO2006074392A2 (en) * | 2005-01-06 | 2006-07-13 | Genentech, Inc. | Cancer prognostic, diagnostic and treatment methods |
-
2006
- 2006-01-31 CA CA002594636A patent/CA2594636A1/en not_active Abandoned
- 2006-01-31 WO PCT/US2006/003502 patent/WO2006083936A2/en not_active Ceased
- 2006-01-31 EP EP06720045A patent/EP1844076A2/en not_active Ceased
- 2006-01-31 NZ NZ556317A patent/NZ556317A/en not_active IP Right Cessation
- 2006-01-31 AU AU2006210837A patent/AU2006210837B2/en not_active Ceased
- 2006-01-31 JP JP2007553371A patent/JP2008537673A/ja active Pending
-
2007
- 2007-07-31 US US11/831,787 patent/US7767205B2/en not_active Expired - Fee Related
-
2010
- 2010-06-08 US US12/796,496 patent/US20100278842A1/en not_active Abandoned
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