JP2008534091A5 - - Google Patents
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- Publication number
- JP2008534091A5 JP2008534091A5 JP2008503352A JP2008503352A JP2008534091A5 JP 2008534091 A5 JP2008534091 A5 JP 2008534091A5 JP 2008503352 A JP2008503352 A JP 2008503352A JP 2008503352 A JP2008503352 A JP 2008503352A JP 2008534091 A5 JP2008534091 A5 JP 2008534091A5
- Authority
- JP
- Japan
- Prior art keywords
- dry
- main body
- inner diameter
- powder
- loading inlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims description 71
- 229940079593 drug Drugs 0.000 claims description 62
- 239000000843 powder Substances 0.000 claims description 44
- 230000000149 penetrating effect Effects 0.000 claims description 6
- 238000012387 aerosolization Methods 0.000 claims description 5
- 210000000214 mouth Anatomy 0.000 description 17
- 238000010586 diagram Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 210000002345 respiratory system Anatomy 0.000 description 5
- 239000000443 aerosol Substances 0.000 description 4
- 239000008187 granular material Substances 0.000 description 3
- 230000009885 systemic effect Effects 0.000 description 3
- 230000000903 blocking effect Effects 0.000 description 2
- 229940112141 dry powder inhaler Drugs 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 210000003800 pharynx Anatomy 0.000 description 2
- 206010011409 Cross infection Diseases 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 208000018569 Respiratory Tract disease Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100386811A CN100431634C (zh) | 2005-04-04 | 2005-04-04 | 干粉气溶胶化吸入器 |
| CN200510038681.1 | 2005-04-04 | ||
| PCT/CN2006/000381 WO2006105709A1 (en) | 2005-04-04 | 2006-03-13 | Dry powder aerosolizing inhaler |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008534091A JP2008534091A (ja) | 2008-08-28 |
| JP2008534091A5 true JP2008534091A5 (enExample) | 2009-05-07 |
| JP5086988B2 JP5086988B2 (ja) | 2012-11-28 |
Family
ID=35038170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008503352A Expired - Fee Related JP5086988B2 (ja) | 2005-04-04 | 2006-03-13 | 乾粉エアロゾル化吸入器 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8978645B2 (enExample) |
| EP (1) | EP1872817B1 (enExample) |
| JP (1) | JP5086988B2 (enExample) |
| CN (1) | CN100431634C (enExample) |
| AT (1) | ATE539785T1 (enExample) |
| WO (1) | WO2006105709A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| JP4681231B2 (ja) | 2002-03-20 | 2011-05-11 | マンカインド コーポレイション | 吸入装置 |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| HUE025151T2 (en) | 2004-08-23 | 2016-01-28 | Mannkind Corp | Diceto-piperazine salts for drug delivery |
| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
| CN104383546B (zh) | 2006-02-22 | 2021-03-02 | 曼金德公司 | 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法 |
| EP2534957B1 (en) | 2007-12-14 | 2015-05-27 | AeroDesigns, Inc | Delivering aerosolizable products |
| MY155524A (en) | 2008-06-13 | 2015-10-30 | Mannkind Corp | A dry powder inhaler and system for drug delivery |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| EP2609954B1 (en) * | 2008-06-20 | 2021-12-29 | MannKind Corporation | An interactive apparatus for real-time profiling of inhalation efforts |
| TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| US8538707B2 (en) | 2009-03-11 | 2013-09-17 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| AU2010259943C1 (en) | 2009-06-12 | 2016-03-03 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
| US8827946B2 (en) | 2009-07-31 | 2014-09-09 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal granisetron and nasal applicator |
| JP5784622B2 (ja) | 2009-11-03 | 2015-09-24 | マンカインド コーポレ−ション | 吸入活動をシミュレートするための装置及び方法 |
| RU2531455C2 (ru) | 2010-06-21 | 2014-10-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
| CN102553040B (zh) * | 2010-12-17 | 2014-07-02 | 陈庆堂 | 滤出药粉吸入器 |
| ES2659761T3 (es) | 2011-01-31 | 2018-03-19 | Shin Nippon Biomedical Laboratories, Ltd. | Dispositivos de administración intranasal |
| MX353285B (es) | 2011-04-01 | 2018-01-05 | Mannkind Corp | Paquete de blister para cartuchos farmaceuticos. |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| HK1201475A1 (en) | 2011-10-24 | 2015-09-04 | Mannkind Corporation | Methods and compositions for treating pain |
| AU2013289957B2 (en) | 2012-07-12 | 2017-02-23 | Mannkind Corporation | Dry powder drug delivery systems and methods |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| BR112015023168B1 (pt) | 2013-03-15 | 2021-08-10 | Mannkind Corporation | Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina |
| BR122019026637B1 (pt) | 2013-07-18 | 2023-09-26 | Mannkind Corporation | Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco |
| CA2920488C (en) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Insufflation apparatus and methods |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| CN106075677B (zh) * | 2016-08-08 | 2022-06-10 | 中山市美捷时包装制品有限公司 | 一种干粉吸入装置的促动机构 |
| US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
| CN109821118B (zh) * | 2017-11-23 | 2025-12-23 | 正大天晴药业集团股份有限公司 | 新型肺部药物输送系统 |
| KR102840146B1 (ko) * | 2018-03-26 | 2025-08-01 | 필립모리스 프로덕츠 에스.에이. | 천공형 다공성 지지 요소를 갖는 흡입기 |
| CN115702961B (zh) * | 2021-08-03 | 2026-05-19 | 上海臣邦医药科技股份有限公司 | 一种单剂量可抛弃型粉雾剂装置 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI69963C (fi) * | 1984-10-04 | 1986-09-12 | Orion Yhtymae Oy | Doseringsanordning |
| US5201308A (en) * | 1990-02-14 | 1993-04-13 | Newhouse Michael T | Powder inhaler |
| GB9015522D0 (en) * | 1990-07-13 | 1990-08-29 | Braithwaite Philip W | Inhaler |
| DE4211475A1 (de) * | 1991-12-14 | 1993-06-17 | Asta Medica Ag | Pulverinhalator |
| US5239993A (en) * | 1992-08-26 | 1993-08-31 | Glaxo Inc. | Dosage inhalator providing optimized compound inhalation trajectory |
| US5349947A (en) * | 1993-07-15 | 1994-09-27 | Newhouse Michael T | Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow |
| DE69535897D1 (de) * | 1994-03-07 | 2009-01-22 | Nektar Therapeutics | Verfahren und Zusammensetzung für die pulmonale Darreichung von Insulin |
| FR2718968B1 (fr) * | 1994-04-20 | 1996-07-26 | Valois Sa | Insert délimitant une chambre de dosage d'un inhalateur. |
| US6182655B1 (en) * | 1995-12-07 | 2001-02-06 | Jago Research Ag | Inhaler for multiple dosed administration of a pharmacological dry powder |
| JP3328131B2 (ja) * | 1996-03-15 | 2002-09-24 | 株式会社ユニシアジェックス | 吸入式投薬器 |
| GB9626263D0 (en) * | 1996-12-18 | 1997-02-05 | Innovata Biomed Ltd | Powder inhaler |
| JP3530004B2 (ja) * | 1998-02-06 | 2004-05-24 | 株式会社日立ユニシアオートモティブ | 吸入式投薬器 |
| US6234169B1 (en) * | 1998-08-14 | 2001-05-22 | Arthur Slutsky | Inhaler |
| JP2000217917A (ja) * | 1999-01-27 | 2000-08-08 | Unisia Jecs Corp | 吸入式投薬器 |
| JP2000217919A (ja) * | 1999-01-28 | 2000-08-08 | Unisia Jecs Corp | 吸入式投薬器 |
| GB2353222B (en) * | 1999-06-23 | 2001-09-19 | Cambridge Consultants | Inhalers |
| US7464706B2 (en) * | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| CN2391625Y (zh) | 1999-11-07 | 2000-08-16 | 范崇盛 | 新型多用途雾化吸入器 |
| GB0015043D0 (en) | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Medicament dispenser |
| PE20020066A1 (es) * | 2000-06-23 | 2002-02-23 | Norton Healthcare Ltd | Deposito de dosis medidas previamente para inhalador de polvo seco accionado por la respiracion |
| DE10040528A1 (de) * | 2000-08-18 | 2002-02-28 | Pari Gmbh | Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke |
| PT1386630E (pt) * | 2002-07-31 | 2006-09-29 | Chiesi Farma Spa | Inalador em po |
| DE10244795A1 (de) * | 2002-09-26 | 2004-04-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| JP3616877B2 (ja) * | 2002-10-11 | 2005-02-02 | 大塚製薬株式会社 | 粉末吸入器 |
| JP3590848B1 (ja) * | 2003-05-09 | 2004-11-17 | 大塚製薬株式会社 | 粉末吸入器 |
| CN2794531Y (zh) * | 2005-04-04 | 2006-07-12 | 陈庆堂 | 干粉气溶胶化吸入器 |
-
2005
- 2005-04-04 CN CNB2005100386811A patent/CN100431634C/zh not_active Expired - Fee Related
-
2006
- 2006-03-13 JP JP2008503352A patent/JP5086988B2/ja not_active Expired - Fee Related
- 2006-03-13 AT AT06722039T patent/ATE539785T1/de active
- 2006-03-13 US US11/887,755 patent/US8978645B2/en not_active Expired - Fee Related
- 2006-03-13 EP EP06722039A patent/EP1872817B1/en not_active Revoked
- 2006-03-13 WO PCT/CN2006/000381 patent/WO2006105709A1/zh not_active Ceased
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