JP2008534091A5 - - Google Patents
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- Publication number
- JP2008534091A5 JP2008534091A5 JP2008503352A JP2008503352A JP2008534091A5 JP 2008534091 A5 JP2008534091 A5 JP 2008534091A5 JP 2008503352 A JP2008503352 A JP 2008503352A JP 2008503352 A JP2008503352 A JP 2008503352A JP 2008534091 A5 JP2008534091 A5 JP 2008534091A5
- Authority
- JP
- Japan
- Prior art keywords
- dry
- main body
- inner diameter
- powder
- loading inlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims description 71
- 229940079593 drug Drugs 0.000 claims description 62
- 239000000843 powder Substances 0.000 claims description 44
- 230000000149 penetrating effect Effects 0.000 claims description 6
- 238000012387 aerosolization Methods 0.000 claims description 5
- 210000000214 mouth Anatomy 0.000 description 17
- 238000010586 diagram Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 210000002345 respiratory system Anatomy 0.000 description 5
- 239000000443 aerosol Substances 0.000 description 4
- 239000008187 granular material Substances 0.000 description 3
- 230000009885 systemic effect Effects 0.000 description 3
- 230000000903 blocking effect Effects 0.000 description 2
- 229940112141 dry powder inhaler Drugs 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 210000003800 pharynx Anatomy 0.000 description 2
- 206010011409 Cross infection Diseases 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 208000018569 Respiratory Tract disease Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100386811A CN100431634C (zh) | 2005-04-04 | 2005-04-04 | 干粉气溶胶化吸入器 |
| CN200510038681.1 | 2005-04-04 | ||
| PCT/CN2006/000381 WO2006105709A1 (en) | 2005-04-04 | 2006-03-13 | Dry powder aerosolizing inhaler |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008534091A JP2008534091A (ja) | 2008-08-28 |
| JP2008534091A5 true JP2008534091A5 (enExample) | 2009-05-07 |
| JP5086988B2 JP5086988B2 (ja) | 2012-11-28 |
Family
ID=35038170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008503352A Expired - Fee Related JP5086988B2 (ja) | 2005-04-04 | 2006-03-13 | 乾粉エアロゾル化吸入器 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8978645B2 (enExample) |
| EP (1) | EP1872817B1 (enExample) |
| JP (1) | JP5086988B2 (enExample) |
| CN (1) | CN100431634C (enExample) |
| AT (1) | ATE539785T1 (enExample) |
| WO (1) | WO2006105709A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| ATE385193T1 (de) | 2002-03-20 | 2008-02-15 | Mannkind Corp | Inhalationsgerät |
| DK1786784T3 (da) | 2004-08-20 | 2011-02-14 | Mannkind Corp | Katalyse af diketopiperazinsyntese |
| BRPI0514293B1 (pt) | 2004-08-23 | 2022-07-19 | Mannkind Corporation | Sistema microparticulado para distribuição de droga |
| DK1928423T3 (en) | 2005-09-14 | 2016-02-29 | Mannkind Corp | A method for drug formulation based on increasing the affinity of the active substances to the crystalline microparticle surfaces |
| CA2643464C (en) | 2006-02-22 | 2018-09-04 | Mannkind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| WO2011163272A1 (en) | 2010-06-21 | 2011-12-29 | Mannkind Corporation | Dry powder drug delivery system and methods |
| DK2230934T3 (da) | 2007-12-14 | 2012-11-26 | Aerodesigns Inc | Afgivelse af aerosoliserbare næringsmiddelprodukter |
| CN106039494B (zh) | 2008-06-13 | 2019-12-24 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| BRPI0914308B8 (pt) | 2008-06-20 | 2021-06-22 | Mannkind Corp | sistema de inalação |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| WO2010105094A1 (en) | 2009-03-11 | 2010-09-16 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| MY186975A (en) | 2009-06-12 | 2021-08-26 | Mannkind Corp | Diketopiperazine microparticles with defined specific surface areas |
| WO2011013003A2 (en) | 2009-07-31 | 2011-02-03 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal granisetron and nasal applicator |
| EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
| CN102553040B (zh) * | 2010-12-17 | 2014-07-02 | 陈庆堂 | 滤出药粉吸入器 |
| CA2825541C (en) | 2011-01-31 | 2020-06-02 | Tatsuo Tsutsui | Intranasal delivery devices |
| MY180552A (en) | 2011-04-01 | 2020-12-02 | Mannkind Corp | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| JP6018640B2 (ja) | 2011-10-24 | 2016-11-02 | マンカインド コーポレイション | 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム |
| DK2872205T3 (en) | 2012-07-12 | 2017-02-27 | Mannkind Corp | DRY POWDER FORMAL ADMINISTRATION SYSTEM |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| KR102391750B1 (ko) | 2013-03-15 | 2022-04-28 | 맨카인드 코포레이션 | 미세결정성 디케토피페라진 조성물 및 방법 |
| EP3021834A1 (en) | 2013-07-18 | 2016-05-25 | MannKind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
| US11446127B2 (en) | 2013-08-05 | 2022-09-20 | Mannkind Corporation | Insufflation apparatus and methods |
| WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| CN106075677B (zh) * | 2016-08-08 | 2022-06-10 | 中山市美捷时包装制品有限公司 | 一种干粉吸入装置的促动机构 |
| US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
| CN109821118A (zh) * | 2017-11-23 | 2019-05-31 | 正大天晴药业集团股份有限公司 | 新型肺部药物输送系统 |
| CN111801026B (zh) * | 2018-03-26 | 2024-04-19 | 菲利普莫里斯生产公司 | 具有有孔的多孔支撑元件的吸入器 |
| CN115702961A (zh) * | 2021-08-03 | 2023-02-17 | 上海臣邦医药科技股份有限公司 | 一种单剂量可抛弃型粉雾剂装置 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI69963C (fi) * | 1984-10-04 | 1986-09-12 | Orion Yhtymae Oy | Doseringsanordning |
| US5201308A (en) * | 1990-02-14 | 1993-04-13 | Newhouse Michael T | Powder inhaler |
| GB9015522D0 (en) * | 1990-07-13 | 1990-08-29 | Braithwaite Philip W | Inhaler |
| DE4211475A1 (de) | 1991-12-14 | 1993-06-17 | Asta Medica Ag | Pulverinhalator |
| US5239993A (en) * | 1992-08-26 | 1993-08-31 | Glaxo Inc. | Dosage inhalator providing optimized compound inhalation trajectory |
| US5349947A (en) * | 1993-07-15 | 1994-09-27 | Newhouse Michael T | Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow |
| JPH10501519A (ja) * | 1994-03-07 | 1998-02-10 | インヘイル・セラピューティック・システムズ | インシュリンを肺に送給できる方法および組成物 |
| FR2718968B1 (fr) * | 1994-04-20 | 1996-07-26 | Valois Sa | Insert délimitant une chambre de dosage d'un inhalateur. |
| ATE193455T1 (de) * | 1995-12-07 | 2000-06-15 | Jago Pharma Ag | Inhalator zur mehrfachen dosisweisen abgabe eines pharmakologischen trockenpulvers |
| JP3328131B2 (ja) * | 1996-03-15 | 2002-09-24 | 株式会社ユニシアジェックス | 吸入式投薬器 |
| GB9626263D0 (en) * | 1996-12-18 | 1997-02-05 | Innovata Biomed Ltd | Powder inhaler |
| JP3530004B2 (ja) * | 1998-02-06 | 2004-05-24 | 株式会社日立ユニシアオートモティブ | 吸入式投薬器 |
| US6234169B1 (en) * | 1998-08-14 | 2001-05-22 | Arthur Slutsky | Inhaler |
| JP2000217917A (ja) * | 1999-01-27 | 2000-08-08 | Unisia Jecs Corp | 吸入式投薬器 |
| JP2000217919A (ja) * | 1999-01-28 | 2000-08-08 | Unisia Jecs Corp | 吸入式投薬器 |
| GB2353222B (en) * | 1999-06-23 | 2001-09-19 | Cambridge Consultants | Inhalers |
| US7464706B2 (en) * | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| CN2391625Y (zh) | 1999-11-07 | 2000-08-16 | 范崇盛 | 新型多用途雾化吸入器 |
| GB0015043D0 (en) | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Medicament dispenser |
| PE20020066A1 (es) * | 2000-06-23 | 2002-02-23 | Norton Healthcare Ltd | Deposito de dosis medidas previamente para inhalador de polvo seco accionado por la respiracion |
| DE10040528A1 (de) * | 2000-08-18 | 2002-02-28 | Pari Gmbh | Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke |
| EP1386630B1 (en) * | 2002-07-31 | 2006-05-17 | CHIESI FARMACEUTICI S.p.A. | Powder inhaler |
| DE10244795A1 (de) * | 2002-09-26 | 2004-04-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| JP3590848B1 (ja) * | 2003-05-09 | 2004-11-17 | 大塚製薬株式会社 | 粉末吸入器 |
| JP3616877B2 (ja) * | 2002-10-11 | 2005-02-02 | 大塚製薬株式会社 | 粉末吸入器 |
| CN2794531Y (zh) * | 2005-04-04 | 2006-07-12 | 陈庆堂 | 干粉气溶胶化吸入器 |
-
2005
- 2005-04-04 CN CNB2005100386811A patent/CN100431634C/zh not_active Expired - Fee Related
-
2006
- 2006-03-13 JP JP2008503352A patent/JP5086988B2/ja not_active Expired - Fee Related
- 2006-03-13 AT AT06722039T patent/ATE539785T1/de active
- 2006-03-13 WO PCT/CN2006/000381 patent/WO2006105709A1/zh not_active Ceased
- 2006-03-13 US US11/887,755 patent/US8978645B2/en not_active Expired - Fee Related
- 2006-03-13 EP EP06722039A patent/EP1872817B1/en not_active Revoked
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